{"reactions": [{"name": "L-Alanine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ala_L_LPAREN_e_RPAREN_"]}, "metabolites": {"ala__L_e": -1.0}, "id": "EX_ala__L_e", "gene_reaction_rule": ""}, {"name": "Allantoin exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_alltn_LPAREN_e_RPAREN_"]}, "metabolites": {"alltn_e": -1.0}, "id": "EX_alltn_e", "gene_reaction_rule": ""}, {"name": "Allantoate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_alltt_LPAREN_e_RPAREN_"]}, "metabolites": {"alltt_e": -1.0}, "id": "EX_alltt_e", "gene_reaction_rule": ""}, {"name": "S Adenosyl L methionine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_amet_LPAREN_e_RPAREN_"]}, "metabolites": {"amet_e": -1.0}, "id": "EX_amet_e", "gene_reaction_rule": ""}, {"name": "D Arabinose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_arab_D_LPAREN_e_RPAREN_"]}, "metabolites": {"arab__D_e": -1.0}, "id": "EX_arab__D_e", "gene_reaction_rule": ""}, {"name": "L-Arabinose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_arab_L_LPAREN_e_RPAREN_"]}, "metabolites": {"arab__L_e": -1.0}, "id": "EX_arab__L_e", "gene_reaction_rule": ""}, {"name": "L-Arginine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_arg_L_LPAREN_e_RPAREN_"]}, "metabolites": {"arg__L_e": -1.0}, "id": "EX_arg__L_e", "gene_reaction_rule": ""}, {"name": "L-Asparagine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_asn_L_LPAREN_e_RPAREN_"]}, "metabolites": {"asn__L_e": -1.0}, "id": "EX_asn__L_e", "gene_reaction_rule": ""}, {"name": "L-Aspartate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_asp_L_LPAREN_e_RPAREN_"]}, "metabolites": {"asp__L_e": -1.0}, "id": "EX_asp__L_e", "gene_reaction_rule": ""}, {"name": "Biotin exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_btn_LPAREN_e_RPAREN_"]}, "metabolites": {"btn_e": -1.0}, "id": "EX_btn_e", "gene_reaction_rule": ""}, {"name": "Choline exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_chol_LPAREN_e_RPAREN_"]}, "metabolites": {"chol_e": -1.0}, "id": "EX_chol_e", "gene_reaction_rule": ""}, {"name": "Citrate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_cit_LPAREN_e_RPAREN_"]}, "metabolites": {"cit_e": -1.0}, "id": "EX_cit_e", "gene_reaction_rule": ""}, {"name": "CO2 exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_co2_LPAREN_e_RPAREN_"]}, "metabolites": {"co2_e": -1.0}, "id": "EX_co2_e", "gene_reaction_rule": ""}, {"name": "L-Carnitine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_crn_LPAREN_e_RPAREN_"]}, "metabolites": {"crn_e": -1.0}, "id": "EX_crn_e", "gene_reaction_rule": ""}, {"name": "Cytosine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_csn_LPAREN_e_RPAREN_"]}, "metabolites": {"csn_e": -1.0}, "id": "EX_csn_e", "gene_reaction_rule": ""}, {"name": "L-Cysteine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_cys_L_LPAREN_e_RPAREN_"]}, "metabolites": {"cys__L_e": -1.0}, "id": "EX_cys__L_e", "gene_reaction_rule": ""}, {"name": "Cytidine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_cytd_LPAREN_e_RPAREN_"]}, "metabolites": {"cytd_e": -1.0}, "id": "EX_cytd_e", "gene_reaction_rule": ""}, {"name": "Deoxyadenosine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_dad_2_LPAREN_e_RPAREN_"]}, "metabolites": {"dad_2_e": -1.0}, "id": "EX_dad_2_e", "gene_reaction_rule": ""}, {"name": "7 8 Diaminononanoate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_dann_LPAREN_e_RPAREN_"]}, "metabolites": {"dann_e": -1.0}, "id": "EX_dann_e", "gene_reaction_rule": ""}, {"name": "Deoxycytidine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_dcyt_LPAREN_e_RPAREN_"]}, "metabolites": {"dcyt_e": -1.0}, "id": "EX_dcyt_e", "gene_reaction_rule": ""}, {"name": "Deoxyguanosine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_dgsn_LPAREN_e_RPAREN_"]}, "metabolites": {"dgsn_e": -1.0}, "id": "EX_dgsn_e", "gene_reaction_rule": ""}, {"name": "Deoxyinosine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_din_LPAREN_e_RPAREN_"]}, "metabolites": {"din_e": -1.0}, "id": "EX_din_e", "gene_reaction_rule": ""}, {"name": "DTTP exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_dttp_LPAREN_e_RPAREN_"]}, "metabolites": {"dttp_e": -1.0}, "id": "EX_dttp_e", "gene_reaction_rule": ""}, {"name": "Deoxyuridine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_duri_LPAREN_e_RPAREN_"]}, "metabolites": {"duri_e": -1.0}, "id": "EX_duri_e", "gene_reaction_rule": ""}, {"name": "Ergosterol exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ergst_LPAREN_e_RPAREN_"]}, "metabolites": {"ergst_e": -1.0}, "id": "EX_ergst_e", "gene_reaction_rule": ""}, {"name": "Ethanol exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_etoh_LPAREN_e_RPAREN_"]}, "metabolites": {"etoh_e": -1.0}, "id": "EX_etoh_e", "gene_reaction_rule": ""}, {"name": "FMN exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_fmn_LPAREN_e_RPAREN_"]}, "metabolites": {"fmn_e": -1.0}, "id": "EX_fmn_e", "gene_reaction_rule": ""}, {"name": "Formate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_for_LPAREN_e_RPAREN_"]}, "metabolites": {"for_e": -1.0}, "id": "EX_for_e", "gene_reaction_rule": ""}, {"name": "D-Fructose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_fru_LPAREN_e_RPAREN_"]}, "metabolites": {"fru_e": -1.0}, "id": "EX_fru_e", "gene_reaction_rule": ""}, {"name": "Fumarate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_fum_LPAREN_e_RPAREN_"]}, "metabolites": {"fum_e": -1.0}, "id": "EX_fum_e", "gene_reaction_rule": ""}, {"name": "D-Galactose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_gal_LPAREN_e_RPAREN_"]}, "metabolites": {"gal_e": -1.0}, "id": "EX_gal_e", "gene_reaction_rule": ""}, {"name": "D-Glucosamine 6-phosphate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_gam6p_LPAREN_e_RPAREN_"]}, "metabolites": {"gam6p_e": -1.0}, "id": "EX_gam6p_e", "gene_reaction_rule": ""}, {"name": "Glycolaldehyde exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_gcald_LPAREN_e_RPAREN_"]}, "metabolites": {"gcald_e": -1.0}, "id": "EX_gcald_e", "gene_reaction_rule": ""}, {"subsystem": "Extracellular exchange", "name": "D-Glucose exchange", "upper_bound": 999999.0, "lower_bound": -1.0, "notes": {"original_bigg_ids": ["EX_glc_LPAREN_e_RPAREN_"]}, "metabolites": {"glc__D_e": -1.0}, "id": "EX_glc__D_e", "gene_reaction_rule": ""}, {"name": "L-Glutamine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_gln_L_LPAREN_e_RPAREN_"]}, "metabolites": {"gln__L_e": -1.0}, "id": "EX_gln__L_e", "gene_reaction_rule": ""}, {"name": "L-Glutamate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_glu_L_LPAREN_e_RPAREN_"]}, "metabolites": {"glu__L_e": -1.0}, "id": "EX_glu__L_e", "gene_reaction_rule": ""}, {"name": "Glycine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_gly_LPAREN_e_RPAREN_"]}, "metabolites": {"gly_e": -1.0}, "id": "EX_gly_e", "gene_reaction_rule": ""}, {"name": "Glycerol exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_glyc_LPAREN_e_RPAREN_"]}, "metabolites": {"glyc_e": -1.0}, "id": "EX_glyc_e", "gene_reaction_rule": ""}, {"name": "Guanosine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_gsn_LPAREN_e_RPAREN_"]}, "metabolites": {"gsn_e": -1.0}, "id": "EX_gsn_e", "gene_reaction_rule": ""}, {"name": "Oxidized glutathione exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_gthox_LPAREN_e_RPAREN_"]}, "metabolites": {"gthox_e": -1.0}, "id": "EX_gthox_e", "gene_reaction_rule": ""}, {"name": "Guanine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_gua_LPAREN_e_RPAREN_"]}, "metabolites": {"gua_e": -1.0}, "id": "EX_gua_e", "gene_reaction_rule": ""}, {"name": "H2O exchange", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["EX_h2o_LPAREN_e_RPAREN_"]}, "metabolites": {"h2o_e": -1.0}, "id": "EX_h2o_e", "gene_reaction_rule": ""}, {"name": "H+ exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_h_LPAREN_e_RPAREN_"]}, "metabolites": {"h_e": -1.0}, "id": "EX_h_e", "gene_reaction_rule": ""}, {"name": "Hexadecanoate (n-C16:0) exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_hdca_LPAREN_e_RPAREN_"]}, "metabolites": {"hdca_e": -1.0}, "id": "EX_hdca_e", "gene_reaction_rule": ""}, {"name": "Hexadecenoate (n-C16:1) exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_hdcea_LPAREN_e_RPAREN_"]}, "metabolites": {"hdcea_e": -1.0}, "id": "EX_hdcea_e", "gene_reaction_rule": ""}, {"name": "L-Histidine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_his_L_LPAREN_e_RPAREN_"]}, "metabolites": {"his__L_e": -1.0}, "id": "EX_his__L_e", "gene_reaction_rule": ""}, {"name": "Hypoxanthine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_hxan_LPAREN_e_RPAREN_"]}, "metabolites": {"hxan_e": -1.0}, "id": "EX_hxan_e", "gene_reaction_rule": ""}, {"name": "L-Isoleucine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ile_L_LPAREN_e_RPAREN_"]}, "metabolites": {"ile__L_e": -1.0}, "id": "EX_ile__L_e", "gene_reaction_rule": ""}, {"name": "Myo-Inositol exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_inost_LPAREN_e_RPAREN_"]}, "metabolites": {"inost_e": -1.0}, "id": "EX_inost_e", "gene_reaction_rule": ""}, {"name": "Inosine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ins_LPAREN_e_RPAREN_"]}, "metabolites": {"ins_e": -1.0}, "id": "EX_ins_e", "gene_reaction_rule": ""}, {"name": "K+ exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_k_LPAREN_e_RPAREN_"]}, "metabolites": {"k_e": -1.0}, "id": "EX_k_e", "gene_reaction_rule": ""}, {"name": "L-Lactate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_lac_L_LPAREN_e_RPAREN_"]}, "metabolites": {"lac__L_e": -1.0}, "id": "EX_lac__L_e", "gene_reaction_rule": ""}, {"name": "L-Leucine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_leu_L_LPAREN_e_RPAREN_"]}, "metabolites": {"leu__L_e": -1.0}, "id": "EX_leu__L_e", "gene_reaction_rule": ""}, {"name": "L-Lysine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_lys_L_LPAREN_e_RPAREN_"]}, "metabolites": {"lys__L_e": -1.0}, "id": "EX_lys__L_e", "gene_reaction_rule": ""}, {"name": "L-Malate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_mal_L_LPAREN_e_RPAREN_"]}, "metabolites": {"mal__L_e": -1.0}, "id": "EX_mal__L_e", "gene_reaction_rule": ""}, {"name": "Maltose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_malt_LPAREN_e_RPAREN_"]}, "metabolites": {"malt_e": -1.0}, "id": "EX_malt_e", "gene_reaction_rule": ""}, {"name": "D-Mannose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_man_LPAREN_e_RPAREN_"]}, "metabolites": {"man_e": -1.0}, "id": "EX_man_e", "gene_reaction_rule": ""}, {"name": "Melibiose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_melib_LPAREN_e_RPAREN_"]}, "metabolites": {"melib_e": -1.0}, "id": "EX_melib_e", "gene_reaction_rule": ""}, {"name": "L-Methionine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_met_L_LPAREN_e_RPAREN_"]}, "metabolites": {"met__L_e": -1.0}, "id": "EX_met__L_e", "gene_reaction_rule": ""}, {"name": "S-Methyl-L-methionine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_mmet_LPAREN_e_RPAREN_"]}, "metabolites": {"mmet_e": -1.0}, "id": "EX_mmet_e", "gene_reaction_rule": ""}, {"name": "Sodium exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_na1_LPAREN_e_RPAREN_"]}, "metabolites": {"na1_e": -1.0}, "id": "EX_na1_e", "gene_reaction_rule": ""}, {"name": "Ammonia exchange", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["EX_nh4_LPAREN_e_RPAREN_"]}, "metabolites": {"nh4_e": -1.0}, "id": "EX_nh4_e", "gene_reaction_rule": ""}, {"name": "NMN exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_nmn_LPAREN_e_RPAREN_"]}, "metabolites": {"nmn_e": -1.0}, "id": "EX_nmn_e", "gene_reaction_rule": ""}, {"name": "O2 exchange", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["EX_o2_LPAREN_e_RPAREN_"]}, "metabolites": {"o2_e": -1.0}, "id": "EX_o2_e", "gene_reaction_rule": ""}, {"name": "Octadecanoate (n-C18:0) exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ocdca_LPAREN_e_RPAREN_"]}, "metabolites": {"ocdca_e": -1.0}, "id": "EX_ocdca_e", "gene_reaction_rule": ""}, {"name": "Octadecenoate (n-C18:1) exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ocdcea_LPAREN_e_RPAREN_"]}, "metabolites": {"ocdcea_e": -1.0}, "id": "EX_ocdcea_e", "gene_reaction_rule": ""}, {"name": "Octadecynoate n C182 exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ocdcya_LPAREN_e_RPAREN_"]}, "metabolites": {"ocdcya_e": -1.0}, "id": "EX_ocdcya_e", "gene_reaction_rule": ""}, {"name": "Ornithine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_orn_LPAREN_e_RPAREN_"]}, "metabolites": {"orn_e": -1.0}, "id": "EX_orn_e", "gene_reaction_rule": ""}, {"name": "Adenosine 3 5 bisphosphate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_pap_LPAREN_e_RPAREN_"]}, "metabolites": {"pap_e": -1.0}, "id": "EX_pap_e", "gene_reaction_rule": ""}, {"name": "Peptide exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_pepd_LPAREN_e_RPAREN_"]}, "metabolites": {"pepd_e": -1.0}, "id": "EX_pepd_e", "gene_reaction_rule": ""}, {"name": "L-Phenylalanine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_phe_L_LPAREN_e_RPAREN_"]}, "metabolites": {"phe__L_e": -1.0}, "id": "EX_phe__L_e", "gene_reaction_rule": ""}, {"name": "Phosphate exchange", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["EX_pi_LPAREN_e_RPAREN_"]}, "metabolites": {"pi_e": -1.0}, "id": "EX_pi_e", "gene_reaction_rule": ""}, {"name": "(R)-Pantothenate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_pnto_R_LPAREN_e_RPAREN_"]}, "metabolites": {"pnto__R_e": -1.0}, "id": "EX_pnto__R_e", "gene_reaction_rule": ""}, {"name": "L-Proline exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_pro_L_LPAREN_e_RPAREN_"]}, "metabolites": {"pro__L_e": -1.0}, "id": "EX_pro__L_e", "gene_reaction_rule": ""}, {"name": "Putrescine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ptrc_LPAREN_e_RPAREN_"]}, "metabolites": {"ptrc_e": -1.0}, "id": "EX_ptrc_e", "gene_reaction_rule": ""}, {"name": "Pyruvate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_pyr_LPAREN_e_RPAREN_"]}, "metabolites": {"pyr_e": -1.0}, "id": "EX_pyr_e", "gene_reaction_rule": ""}, {"name": "D-Ribose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_rib_D_LPAREN_e_RPAREN_"]}, "metabolites": {"rib__D_e": -1.0}, "id": "EX_rib__D_e", "gene_reaction_rule": ""}, {"name": "Riboflavin exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ribflv_LPAREN_e_RPAREN_"]}, "metabolites": {"ribflv_e": -1.0}, "id": "EX_ribflv_e", "gene_reaction_rule": ""}, {"name": "D-Sorbitol exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_sbt_D_LPAREN_e_RPAREN_"]}, "metabolites": {"sbt__D_e": -1.0}, "id": "EX_sbt__D_e", "gene_reaction_rule": ""}, {"name": "L Sorbitol exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_sbt_L_LPAREN_e_RPAREN_"]}, "metabolites": {"sbt__L_e": -1.0}, "id": "EX_sbt__L_e", "gene_reaction_rule": ""}, {"name": "L-Serine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ser_L_LPAREN_e_RPAREN_"]}, "metabolites": {"ser__L_e": -1.0}, "id": "EX_ser__L_e", "gene_reaction_rule": ""}, {"name": "Sulfate exchange", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["EX_so4_LPAREN_e_RPAREN_"]}, "metabolites": {"so4_e": -1.0}, "id": "EX_so4_e", "gene_reaction_rule": ""}, {"name": "Spermidine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_spmd_LPAREN_e_RPAREN_"]}, "metabolites": {"spmd_e": -1.0}, "id": "EX_spmd_e", "gene_reaction_rule": ""}, {"name": "Spermine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_sprm_LPAREN_e_RPAREN_"]}, "metabolites": {"sprm_e": -1.0}, "id": "EX_sprm_e", "gene_reaction_rule": ""}, {"name": "L Sorbose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_srb_L_LPAREN_e_RPAREN_"]}, "metabolites": {"srb__L_e": -1.0}, "id": "EX_srb__L_e", "gene_reaction_rule": ""}, {"name": "Succinate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_succ_LPAREN_e_RPAREN_"]}, "metabolites": {"succ_e": -1.0}, "id": "EX_succ_e", "gene_reaction_rule": ""}, {"name": "Sucrose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_sucr_LPAREN_e_RPAREN_"]}, "metabolites": {"sucr_e": -1.0}, "id": "EX_sucr_e", "gene_reaction_rule": ""}, {"name": "Thiamin exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_thm_LPAREN_e_RPAREN_"]}, "metabolites": {"thm_e": -1.0}, "id": "EX_thm_e", "gene_reaction_rule": ""}, {"name": "Thiamin monophosphate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_thmmp_LPAREN_e_RPAREN_"]}, "metabolites": {"thmmp_e": -1.0}, "id": "EX_thmmp_e", "gene_reaction_rule": ""}, {"name": "Thiamine diphosphate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_thmpp_LPAREN_e_RPAREN_"]}, "metabolites": {"thmpp_e": -1.0}, "id": "EX_thmpp_e", "gene_reaction_rule": ""}, {"name": "L-Threonine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_thr_L_LPAREN_e_RPAREN_"]}, "metabolites": {"thr__L_e": -1.0}, "id": "EX_thr__L_e", "gene_reaction_rule": ""}, {"name": "Thymine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_thym_LPAREN_e_RPAREN_"]}, "metabolites": {"thym_e": -1.0}, "id": "EX_thym_e", "gene_reaction_rule": ""}, {"name": "Thymidine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_thymd_LPAREN_e_RPAREN_"]}, "metabolites": {"thymd_e": -1.0}, "id": "EX_thymd_e", "gene_reaction_rule": ""}, {"name": "Trehalose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_tre_LPAREN_e_RPAREN_"]}, "metabolites": {"tre_e": -1.0}, "id": "EX_tre_e", "gene_reaction_rule": ""}, {"name": "L-Tryptophan exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_trp_L_LPAREN_e_RPAREN_"]}, "metabolites": {"trp__L_e": -1.0}, "id": "EX_trp__L_e", "gene_reaction_rule": ""}, {"name": "Tetradecanoate (n-C14:0) exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ttdca_LPAREN_e_RPAREN_"]}, "metabolites": {"ttdca_e": -1.0}, "id": "EX_ttdca_e", "gene_reaction_rule": ""}, {"name": "L-Tyrosine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_tyr_L_LPAREN_e_RPAREN_"]}, "metabolites": {"tyr__L_e": -1.0}, "id": "EX_tyr__L_e", "gene_reaction_rule": ""}, {"name": "Uracil exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ura_LPAREN_e_RPAREN_"]}, "metabolites": {"ura_e": -1.0}, "id": "EX_ura_e", "gene_reaction_rule": ""}, {"name": "Urea exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_urea_LPAREN_e_RPAREN_"]}, "metabolites": {"urea_e": -1.0}, "id": "EX_urea_e", "gene_reaction_rule": ""}, {"name": "Uridine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_uri_LPAREN_e_RPAREN_"]}, "metabolites": {"uri_e": -1.0}, "id": "EX_uri_e", "gene_reaction_rule": ""}, {"name": "L-Valine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_val_L_LPAREN_e_RPAREN_"]}, "metabolites": {"val__L_e": -1.0}, "id": "EX_val__L_e", "gene_reaction_rule": ""}, {"name": "Xanthine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_xan_LPAREN_e_RPAREN_"]}, "metabolites": {"xan_e": -1.0}, "id": "EX_xan_e", "gene_reaction_rule": ""}, {"name": "Xanthosine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_xtsn_LPAREN_e_RPAREN_"]}, "metabolites": {"xtsn_e": -1.0}, "id": "EX_xtsn_e", "gene_reaction_rule": ""}, {"name": "D-Xylose exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_xyl_D_LPAREN_e_RPAREN_"]}, "metabolites": {"xyl__D_e": -1.0}, "id": "EX_xyl__D_e", "gene_reaction_rule": ""}, {"name": "Xylitol exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_xylt_LPAREN_e_RPAREN_"]}, "metabolites": {"xylt_e": -1.0}, "id": "EX_xylt_e", "gene_reaction_rule": ""}, {"name": "Zymosterol exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_zymst_LPAREN_e_RPAREN_"]}, "metabolites": {"zymst_e": -1.0}, "id": "EX_zymst_e", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA100tp"]}, "metabolites": {"dca_x": 1.0, "dca_c": -1.0}, "id": "FA100tp", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty-acyl-ACP hydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FA120ACPH"]}, "metabolites": {"ddca_c": 1.0, "h2o_c": -1.0, "ACP_c": 1.0, "h_c": 1.0, "ddcaACP_c": -1.0}, "id": "FA120ACPHi", "gene_reaction_rule": "YKL182W and YPL231W"}, {"subsystem": "Transport, Mitochondrial", "name": "Fatty acyl ACP mitochondrial transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA120ACPtm"]}, "metabolites": {"ddcaACP_m": -1.0, "ddcaACP_c": 1.0}, "id": "FA120ACPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA120tp"]}, "metabolites": {"ddca_c": -1.0, "ddca_x": 1.0}, "id": "FA120tp", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty-acyl-ACP hydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FA140ACPH"]}, "metabolites": {"h2o_c": -1.0, "ACP_c": 1.0, "ttdca_c": 1.0, "myrsACP_c": -1.0, "h_c": 1.0}, "id": "FA140ACPHi", "gene_reaction_rule": "YKL182W and YPL231W"}, {"subsystem": "Transport, Mitochondrial", "name": "Fatty acyl ACP mitochondrial transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA140ACPtm"]}, "metabolites": {"myrsACP_m": -1.0, "myrsACP_c": 1.0}, "id": "FA140ACPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport via ABC system", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA140COAabcp"]}, "metabolites": {"pi_x": 1.0, "tdcoa_x": 1.0, "adp_x": 1.0, "h_x": 1.0, "h2o_x": -1.0, "atp_x": -1.0, "tdcoa_c": -1.0}, "id": "FA140COAabcp", "gene_reaction_rule": "YKL188C and YPL147W"}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA140tp"]}, "metabolites": {"ttdca_c": -1.0, "ttdca_x": 1.0}, "id": "FA140tp", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty-acyl-ACP hydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FA141ACPH"]}, "metabolites": {"tdeACP_c": -1.0, "h2o_c": -1.0, "ACP_c": 1.0, "h_c": 1.0, "ttdcea_c": 1.0}, "id": "FA141ACPHi", "gene_reaction_rule": "YKL182W and YPL231W"}, {"subsystem": "Transport, Mitochondrial", "name": "Fatty acyl ACP mitochondrial transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA141ACPtm"]}, "metabolites": {"tdeACP_c": 1.0, "tdeACP_m": -1.0}, "id": "FA141ACPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport via ABC system", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA141COAabcp"]}, "metabolites": {"pi_x": 1.0, "tdecoa_x": 1.0, "adp_x": 1.0, "h_x": 1.0, "h2o_x": -1.0, "atp_x": -1.0, "tdecoa_c": -1.0}, "id": "FA141COAabcp", "gene_reaction_rule": "YKL188C and YPL147W"}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA141tp"]}, "metabolites": {"ttdcea_x": 1.0, "ttdcea_c": -1.0}, "id": "FA141tp", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty-acyl-ACP hydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FA160ACPH"]}, "metabolites": {"h2o_c": -1.0, "ACP_c": 1.0, "hdca_c": 1.0, "h_c": 1.0, "palmACP_c": -1.0}, "id": "FA160ACPHi", "gene_reaction_rule": "YKL182W and YPL231W"}, {"subsystem": "Transport, Mitochondrial", "name": "Fatty acyl ACP mitochondrial transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA160ACPtm"]}, "metabolites": {"palmACP_m": -1.0, "palmACP_c": 1.0}, "id": "FA160ACPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acyl CoA peroxisomal transport via ABC system", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA160COAabcp"]}, "metabolites": {"pi_x": 1.0, "pmtcoa_x": 1.0, "adp_x": 1.0, "h_x": 1.0, "pmtcoa_c": -1.0, "h2o_x": -1.0, "atp_x": -1.0}, "id": "FA160COAabcp", "gene_reaction_rule": "YKL188C and YPL147W"}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA160tp"]}, "metabolites": {"hdca_c": -1.0, "hdca_x": 1.0}, "id": "FA160tp", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty-acyl-ACP hydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FA161ACPH"]}, "metabolites": {"hdcea_c": 1.0, "h2o_c": -1.0, "ACP_c": 1.0, "h_c": 1.0, "hdeACP_c": -1.0}, "id": "FA161ACPHi", "gene_reaction_rule": "YKL182W and YPL231W"}, {"subsystem": "Transport, Mitochondrial", "name": "Fatty acyl ACP mitochondrial transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA161ACPtm"]}, "metabolites": {"hdeACP_m": -1.0, "hdeACP_c": 1.0}, "id": "FA161ACPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acyl CoA peroxisomal transport via ABC system", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA161COAabcp"]}, "metabolites": {"pi_x": 1.0, "hdcoa_c": -1.0, "adp_x": 1.0, "h_x": 1.0, "hdcoa_x": 1.0, "h2o_x": -1.0, "atp_x": -1.0}, "id": "FA161COAabcp", "gene_reaction_rule": "YKL188C and YPL147W"}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA161tp"]}, "metabolites": {"hdcea_c": -1.0, "hdcea_x": 1.0}, "id": "FA161tp", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP hydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FA180ACPH"]}, "metabolites": {"ocdcaACP_c": -1.0, "ACP_c": 1.0, "h_c": 1.0, "h2o_c": -1.0, "ocdca_c": 1.0}, "id": "FA180ACPH", "gene_reaction_rule": "YKL182W and YPL231W"}, {"subsystem": "Transport, Mitochondrial", "name": "Fatty acyl ACP mitochondrial transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA180ACPtm"]}, "metabolites": {"ocdcaACP_c": 1.0, "ocdcaACP_m": -1.0}, "id": "FA180ACPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acyl CoA transport via ABC system", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA180COAabcp"]}, "metabolites": {"pi_x": 1.0, "stcoa_x": 1.0, "adp_x": 1.0, "h_x": 1.0, "stcoa_c": -1.0, "h2o_x": -1.0, "atp_x": -1.0}, "id": "FA180COAabcp", "gene_reaction_rule": "YKL188C and YPL147W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP hydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FA181ACPH"]}, "metabolites": {"octeACP_c": -1.0, "ocdcea_c": 1.0, "h2o_c": -1.0, "ACP_c": 1.0, "h_c": 1.0}, "id": "FA181ACPH", "gene_reaction_rule": "YKL182W and YPL231W"}, {"subsystem": "Transport, Mitochondrial", "name": "Fatty acyl ACP mitochondrial transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA181ACPtm"]}, "metabolites": {"octeACP_c": 1.0, "octeACP_m": -1.0}, "id": "FA181ACPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acyl CoA peroxisomal transport via ABC system", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA181COAabcp"]}, "metabolites": {"pi_x": 1.0, "odecoa_c": -1.0, "adp_x": 1.0, "h_x": 1.0, "odecoa_x": 1.0, "h2o_x": -1.0, "atp_x": -1.0}, "id": "FA181COAabcp", "gene_reaction_rule": "YKL188C and YPL147W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP hydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FA182ACPH"]}, "metabolites": {"ocdcyaACP_c": -1.0, "h2o_c": -1.0, "ACP_c": 1.0, "ocdcya_c": 1.0, "h_c": 1.0}, "id": "FA182ACPH", "gene_reaction_rule": "YKL182W and YPL231W"}, {"subsystem": "Transport, Mitochondrial", "name": "Fatty acyl ACP mitochondrial transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA182ACPtm"]}, "metabolites": {"ocdcyaACP_c": 1.0, "ocdcyaACP_m": -1.0}, "id": "FA182ACPtm", "gene_reaction_rule": ""}, {"subsystem": "Sterol Biosynthesis", "name": "Isopentenyl-diphosphate D-isomerase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["IPDDI"]}, "metabolites": {"dmpp_c": 1.0, "ipdp_c": -1.0}, "id": "IPDDI", "gene_reaction_rule": "YPL117C"}, {"subsystem": "Glutamate metabolism", "name": "Phosphoacetylglucosamine mutase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACGAMPM"]}, "metabolites": {"acgam6p_c": -1.0, "acgam1p_c": 1.0}, "id": "ACGAMPM", "gene_reaction_rule": "YEL058W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Acetylglutamate kinase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACGKm"]}, "metabolites": {"atp_m": -1.0, "adp_m": 1.0, "acglu_m": -1.0, "acg5p_m": 1.0}, "id": "ACGKm", "gene_reaction_rule": "YER069W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "N acteylglutamate synthase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACGSm"]}, "metabolites": {"accoa_m": -1.0, "coa_m": 1.0, "h_m": 1.0, "glu__L_m": -1.0, "acglu_m": 1.0}, "id": "ACGSm", "gene_reaction_rule": "YMR062C or YJL071W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "2 aceto 2 hydroxybutanoate synthase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACHBSm"]}, "metabolites": {"h_m": -1.0, "pyr_m": -1.0, "co2_m": 1.0, "2ahbut_m": 1.0, "2obut_m": -1.0}, "id": "ACHBSm", "gene_reaction_rule": "YCL009C and YMR108W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Acetolactate synthase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACLSm"]}, "metabolites": {"alac__S_m": 1.0, "h_m": -1.0, "pyr_m": -2.0, "co2_m": 1.0}, "id": "ACLSm", "gene_reaction_rule": "YCL009C and YMR108W"}, {"subsystem": "Pyruvate Metabolism", "name": "ACOAH", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACOAH"]}, "metabolites": {"ac_c": -1.0, "coa_c": -1.0, "h_c": -1.0, "h2o_c": 1.0, "accoa_c": 1.0}, "id": "ACOAH", "gene_reaction_rule": "YBL015W"}, {"subsystem": "Fatty Acid Degradation", "name": "Acyl CoA oxidase decanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACOAO4p"]}, "metabolites": {"o2_x": -1.0, "h2o2_x": 1.0, "dcacoa_x": -1.0, "dc2coa_x": 1.0}, "id": "ACOAO4p", "gene_reaction_rule": "YGL205W"}, {"subsystem": "Fatty Acid Degradation", "name": "Acyl CoA oxidase dodecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACOAO5p"]}, "metabolites": {"o2_x": -1.0, "ddcacoa_x": -1.0, "dd2coa_x": 1.0, "h2o2_x": 1.0}, "id": "ACOAO5p", "gene_reaction_rule": "YGL205W"}, {"subsystem": "Fatty Acid Degradation", "name": "Acyl CpA oxidase tetradecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACOAO6p"]}, "metabolites": {"o2_x": -1.0, "td2coa_x": 1.0, "h2o2_x": 1.0, "tdcoa_x": -1.0}, "id": "ACOAO6p", "gene_reaction_rule": "YGL205W"}, {"subsystem": "Fatty Acid Degradation", "name": "Acyl CoA oxidase hexadecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACOAO7p"]}, "metabolites": {"o2_x": -1.0, "h2o2_x": 1.0, "pmtcoa_x": -1.0, "hdd2coa_x": 1.0}, "id": "ACOAO7p", "gene_reaction_rule": "YGL205W"}, {"subsystem": "Fatty Acid Degradation", "name": "Acyl CoA oxidase octadecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACOAO8p"]}, "metabolites": {"od2coa_x": 1.0, "h2o2_x": 1.0, "o2_x": -1.0, "stcoa_x": -1.0}, "id": "ACOAO8p", "gene_reaction_rule": "YGL205W"}, {"subsystem": "Fatty Acid Degradation", "name": "Acyl CoA oxidase hexacanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACOAO9p"]}, "metabolites": {"o2_x": -1.0, "hxc2coa_x": 1.0, "h2o2_x": 1.0, "hexccoa_x": -1.0}, "id": "ACOAO9p", "gene_reaction_rule": "YGL205W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Acetyl-CoA ACP transacylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACOATA"]}, "metabolites": {"acACP_c": 1.0, "ACP_c": -1.0, "coa_c": 1.0, "accoa_c": -1.0}, "id": "ACOATA", "gene_reaction_rule": "YKL182W and YPL231W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Acetyl CoA ACP transacylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACOATAm"]}, "metabolites": {"accoa_m": -1.0, "coa_m": 1.0, "ACP_m": -1.0, "acACP_m": 1.0}, "id": "ACOATAm", "gene_reaction_rule": "YER061C"}, {"subsystem": "Citric Acid Cycle", "name": "Aconitase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACONT"]}, "metabolites": {"icit_c": 1.0, "cit_c": -1.0}, "id": "ACONT", "gene_reaction_rule": "YLR304C"}, {"subsystem": "Citric Acid Cycle", "name": "Aconitate hydratase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACONTm"]}, "metabolites": {"cit_m": -1.0, "icit_m": 1.0}, "id": "ACONTm", "gene_reaction_rule": "YLR304C or YJL200C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Acteylornithine transaminase irreversible mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACOTAim"]}, "metabolites": {"acg5sa_m": -1.0, "acorn_m": 1.0, "glu__L_m": -1.0, "akg_m": 1.0}, "id": "ACOTAim", "gene_reaction_rule": "YOL140W"}, {"subsystem": "Riboflavin Metabolism", "name": "Acid phosphatase extracellular secreted ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACP1e"]}, "metabolites": {"ribflv_e": 1.0, "fmn_e": -1.0, "h2o_e": -1.0, "pi_e": 1.0}, "id": "ACP1e", "gene_reaction_rule": "YAR071W"}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Acyl carrier protein synthase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACPSm"]}, "metabolites": {"coa_m": -1.0, "h_m": 2.0, "h2o_m": -1.0, "pap_m": 1.0, "pan4p_m": 1.0}, "id": "ACPSm", "gene_reaction_rule": "YPL148C"}, {"subsystem": "Transport, Mitochondrial", "name": "O acetylcarnintine transport into mitochondria via diffusion", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACRNtm"]}, "metabolites": {"acrn_c": -1.0, "acrn_m": 1.0}, "id": "ACRNtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Acetylcarnitine transport out of peroxisome", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACRNtp"]}, "metabolites": {"acrn_c": 1.0, "acrn_x": -1.0}, "id": "ACRNtp", "gene_reaction_rule": ""}, {"subsystem": "Pyruvate Metabolism", "name": "Acetyl-CoA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACS"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "accoa_c": 1.0, "ac_c": -1.0}, "id": "ACS", "gene_reaction_rule": "YLR153C"}, {"subsystem": "Pyruvate Metabolism", "name": "Acetyl CoA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACSm"]}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "ac_m": -1.0, "accoa_m": 1.0, "coa_m": -1.0, "amp_m": 1.0}, "id": "ACSm", "gene_reaction_rule": "YAL054C"}, {"subsystem": "Pyruvate Metabolism", "name": "Acetyl CoA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACSp"]}, "metabolites": {"ac_x": -1.0, "accoa_x": 1.0, "amp_x": 1.0, "coa_x": -1.0, "ppi_x": 1.0, "atp_x": -1.0}, "id": "ACSp", "gene_reaction_rule": "YAL054C"}, {"subsystem": "Transport, Extracellular", "name": "Acetate reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACt2r"]}, "metabolites": {"ac_c": 1.0, "h_e": -1.0, "ac_e": -1.0, "h_c": 1.0}, "id": "ACt2r", "gene_reaction_rule": "YCR032W"}, {"subsystem": "Transport, Mitochondrial", "name": "Acetate transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACtm"]}, "metabolites": {"ac_c": -1.0, "ac_m": 1.0}, "id": "ACtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Acetate transport peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACtp"]}, "metabolites": {"ac_x": 1.0, "ac_c": -1.0}, "id": "ACtp", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adenosine deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADA"]}, "metabolites": {"h2o_c": -1.0, "ins_c": 1.0, "adn_c": -1.0, "h_c": -1.0, "nh4_c": 1.0}, "id": "ADA", "gene_reaction_rule": "YNL141W"}, {"subsystem": "Folate Metabolism", "name": "4-aminobenzoate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADCL"]}, "metabolites": {"pyr_c": 1.0, "4adcho_c": -1.0, "h_c": 1.0, "4abz_c": 1.0}, "id": "ADCL", "gene_reaction_rule": ""}, {"subsystem": "Folate Metabolism", "name": "4-amino-4-deoxychorismate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADCS"]}, "metabolites": {"glu__L_c": 1.0, "4adcho_c": 1.0, "chor_c": -1.0, "gln__L_c": -1.0}, "id": "ADCS", "gene_reaction_rule": "YNR033W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adenine deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADD"]}, "metabolites": {"nh4_c": 1.0, "ade_c": -1.0, "h_c": -1.0, "h2o_c": -1.0, "hxan_c": 1.0}, "id": "ADD", "gene_reaction_rule": "YNL141W"}, {"subsystem": "Transport, Extracellular", "name": "Adenine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADEt2"]}, "metabolites": {"ade_c": 1.0, "h_e": -1.0, "h_c": 1.0, "ade_e": -1.0}, "id": "ADEt2", "gene_reaction_rule": "YER060W_A or YER056C or YGL186C or YER060W"}, {"subsystem": "Transport, Mitochondrial", "name": "Adenine reversible transport mitochondria", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ADEtm"]}, "metabolites": {"ade_c": -1.0, "ade_m": 1.0}, "id": "ADEtm", "gene_reaction_rule": ""}, {"subsystem": "Phospholipid Biosynthesis", "name": "Acyldihydroxyacetonephosphate reductase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADHAPR_SC"]}, "metabolites": {"nadph_c": -1.0, "nadp_c": 1.0, "1agly3p_SC_c": -0.01, "h_c": -1.0, "1ag3p_SC_c": 0.01}, "id": "ADHAPR_SC", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adenylate kinase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ADK1"]}, "metabolites": {"atp_c": -1.0, "adp_c": 2.0, "amp_c": -1.0}, "id": "ADK1", "gene_reaction_rule": "YDR226W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adenylate kinase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ADK1m"]}, "metabolites": {"atp_m": -1.0, "adp_m": 2.0, "amp_m": -1.0}, "id": "ADK1m", "gene_reaction_rule": "YER170W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adentylate kinase (GTP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ADK3"]}, "metabolites": {"gtp_c": -1.0, "gdp_c": 1.0, "amp_c": -1.0, "adp_c": 1.0}, "id": "ADK3", "gene_reaction_rule": "YDR226W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adentylate kinase GTP ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ADK3m"]}, "metabolites": {"adp_m": 1.0, "gdp_m": 1.0, "amp_m": -1.0, "gtp_m": -1.0}, "id": "ADK3m", "gene_reaction_rule": "YER170W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adentylate kinase (ITP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ADK4"]}, "metabolites": {"itp_c": -1.0, "adp_c": 1.0, "idp_c": 1.0, "amp_c": -1.0}, "id": "ADK4", "gene_reaction_rule": "YDR226W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adentylate kinase ITP mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ADK4m"]}, "metabolites": {"adp_m": 1.0, "itp_m": -1.0, "amp_m": -1.0, "idp_m": 1.0}, "id": "ADK4m", "gene_reaction_rule": "YER170W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Adenosylmethionine decarboxylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADMDC"]}, "metabolites": {"amet_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "ametam_c": 1.0}, "id": "ADMDC", "gene_reaction_rule": "YOL052C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Adenylate cyclase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADNCYC"]}, "metabolites": {"ppi_c": 1.0, "camp_c": 1.0, "atp_c": -1.0}, "id": "ADNCYC", "gene_reaction_rule": "YJL005W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adenosine kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADNK1"]}, "metabolites": {"adp_c": 1.0, "adn_c": -1.0, "h_c": 1.0, "atp_c": -1.0, "amp_c": 1.0}, "id": "ADNK1", "gene_reaction_rule": "YJR105W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adenosine hydrolase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADNUC"]}, "metabolites": {"h2o_c": -1.0, "ade_c": 1.0, "adn_c": -1.0, "rib__D_c": 1.0}, "id": "ADNUC", "gene_reaction_rule": "YDR400W"}, {"subsystem": "Transport, Extracellular", "name": "Adenosine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADNt2"]}, "metabolites": {"adn_e": -1.0, "h_e": -1.0, "adn_c": 1.0, "h_c": 1.0}, "id": "ADNt2", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Adenine phosphoribosyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADPT"]}, "metabolites": {"ppi_c": 1.0, "ade_c": -1.0, "amp_c": 1.0, "prpp_c": -1.0}, "id": "ADPT", "gene_reaction_rule": "YML022W or YDR441C"}, {"subsystem": "Cysteine Metabolism", "name": "Adenylyl-sulfate kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADSK"]}, "metabolites": {"h_c": 1.0, "paps_c": 1.0, "atp_c": -1.0, "adp_c": 1.0, "aps_c": -1.0}, "id": "ADSK", "gene_reaction_rule": "YKL001C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Adenylsuccinate lyase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ADSL1r"]}, "metabolites": {"fum_c": 1.0, "amp_c": 1.0, "dcamp_c": -1.0}, "id": "ADSL1r", "gene_reaction_rule": "YLR359W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Adenylosuccinate lyase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ADSL2r"]}, "metabolites": {"25aics_c": -1.0, "fum_c": 1.0, "aicar_c": 1.0}, "id": "ADSL2r", "gene_reaction_rule": "YLR359W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Adenylosuccinate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ADSS"]}, "metabolites": {"gdp_c": 1.0, "asp__L_c": -1.0, "gtp_c": -1.0, "h_c": 2.0, "pi_c": 1.0, "imp_c": -1.0, "dcamp_c": 1.0}, "id": "ADSS", "gene_reaction_rule": "YNL220W"}, {"subsystem": "Histidine Metabolism", "name": "ATP phosphoribosyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPPRT"]}, "metabolites": {"ppi_c": 1.0, "prpp_c": -1.0, "atp_c": -1.0, "prbatp_c": 1.0}, "id": "ATPPRT", "gene_reaction_rule": "YER055C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "AMP nucleosidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AMPN"]}, "metabolites": {"r5p_c": 1.0, "ade_c": 1.0, "amp_c": -1.0, "h2o_c": -1.0}, "id": "AMPN", "gene_reaction_rule": "YBR284W or YJL070C or YML035C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Anthranilate phosphoribosyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ANPRT"]}, "metabolites": {"anth_c": -1.0, "ppi_c": 1.0, "prpp_c": -1.0, "pran_c": 1.0}, "id": "ANPRT", "gene_reaction_rule": "YDR354W"}, {"subsystem": "Glutamine Metabolism", "name": "Anthranilate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ANS"]}, "metabolites": {"anth_c": 1.0, "glu__L_c": 1.0, "chor_c": -1.0, "h_c": 1.0, "pyr_c": 1.0, "gln__L_c": -1.0}, "id": "ANS", "gene_reaction_rule": "YER090W or YKL211C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Ap4A hydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AP4AHr"]}, "metabolites": {"ap4a_c": -1.0, "h2o_c": -1.0, "adp_c": 2.0, "h_c": 2.0}, "id": "AP4AH", "gene_reaction_rule": "YDR305C"}, {"subsystem": "Riboflavin Metabolism", "name": "5-amino-6-(5-phosphoribosylamino)uracil reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["APRAUR"]}, "metabolites": {"5apru_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "5aprbu_c": 1.0}, "id": "APRAUR", "gene_reaction_rule": "YBR153W"}, {"subsystem": "Other Amino Acid Metabolism", "name": "N acetylputrescine oxygen oxireductase deaminating ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["APRTO2"]}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "n4abutn_c": 1.0, "h2o2_c": 1.0, "aprut_c": -1.0, "nh4_c": 1.0}, "id": "APRTO2", "gene_reaction_rule": ""}, {"subsystem": "Arabinose Metabolism", "name": "ARAB1D1", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ARAB1D1"]}, "metabolites": {"Dara14lac_c": 1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "arab__D_c": -1.0}, "id": "ARAB1D1", "gene_reaction_rule": "YBR149W"}, {"subsystem": "Arabinose Metabolism", "name": "D arabinose 1 dehydrogenase NADP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ARAB1D2"]}, "metabolites": {"Dara14lac_c": 1.0, "nadp_c": -1.0, "nadph_c": 1.0, "arab__D_c": -1.0, "h_c": 1.0}, "id": "ARAB1D2", "gene_reaction_rule": "YBR149W"}, {"subsystem": "Arabinose Metabolism", "name": "Arabinose reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ARABR"]}, "metabolites": {"abt_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "arab__L_c": -1.0, "h_c": -1.0}, "id": "ARABR", "gene_reaction_rule": "YHR104W"}, {"subsystem": "Transport, Extracellular", "name": "D arabinose reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ARAB_Dt"]}, "metabolites": {"arab__D_e": -1.0, "arab__D_c": 1.0}, "id": "ARAB_Dt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L arabinoase extracellular transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ARAB_Lt"]}, "metabolites": {"arab__L_e": -1.0, "arab__L_c": 1.0}, "id": "ARAB_Lt", "gene_reaction_rule": ""}, {"subsystem": "Arginine and Proline Metabolism", "name": "Arginase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ARGN"]}, "metabolites": {"arg__L_c": -1.0, "h2o_c": -1.0, "urea_c": 1.0, "orn_c": 1.0}, "id": "ARGN", "gene_reaction_rule": "YPL111W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Argininosuccinate lyase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ARGSL"]}, "metabolites": {"argsuc_c": -1.0, "fum_c": 1.0, "arg__L_c": 1.0}, "id": "ARGSL", "gene_reaction_rule": "YHR018C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Argininosuccinate synthase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ARGSSr"]}, "metabolites": {"atp_c": -1.0, "asp__L_c": -1.0, "ppi_c": 1.0, "argsuc_c": 1.0, "amp_c": 1.0, "citr__L_c": -1.0, "h_c": 1.0}, "id": "ARGSS", "gene_reaction_rule": "YOL058W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Arginyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ARGTRS"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "argtrna_c": 1.0, "trnaarg_c": -1.0, "amp_c": 1.0, "arg__L_c": -1.0}, "id": "ARGTRS", "gene_reaction_rule": "YDR341C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Arginyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ARGTRSm"]}, "metabolites": {"argtrna_m": 1.0, "ppi_m": 1.0, "atp_m": -1.0, "trnaarg_m": -1.0, "amp_m": 1.0, "arg__L_m": -1.0}, "id": "ARGTRSm", "gene_reaction_rule": "YHR091C"}, {"subsystem": "Transport, Mitochondrial", "name": "Arginine mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ARGt2m"]}, "metabolites": {"arg__L_m": 1.0, "h_m": 1.0, "arg__L_c": -1.0, "h_c": -1.0}, "id": "ARGt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L arganine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ARGt2r"]}, "metabolites": {"arg__L_e": -1.0, "h_e": -1.0, "arg__L_c": 1.0, "h_c": 1.0}, "id": "ARGt2r", "gene_reaction_rule": "YKR039W or YNL270C or YEL063C"}, {"subsystem": "Histidine Metabolism", "name": "HnRNP arginine N methyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ARMT"]}, "metabolites": {"his__L_c": -1.0, "ahcys_c": 1.0, "NPmehis_c": 1.0, "h_c": 1.0, "amet_c": -1.0}, "id": "ARMT", "gene_reaction_rule": "YBR034C"}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Aspartate semialdehyde dehydrogenase irreversible", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASADi"]}, "metabolites": {"aspsa_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "pi_c": 1.0, "4pasp_c": -1.0}, "id": "ASADi", "gene_reaction_rule": "YDR158W"}, {"subsystem": "Asparagine metabolism", "name": "L-asparaginase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASNN"]}, "metabolites": {"asp__L_c": 1.0, "asn__L_c": -1.0, "h2o_c": -1.0, "nh4_c": 1.0}, "id": "ASNN", "gene_reaction_rule": "YDR321W"}, {"subsystem": "Asparagine metabolism", "name": "L asparaginase extracellular", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASNNe"]}, "metabolites": {"h2o_e": -1.0, "nh4_e": 1.0, "asn__L_e": -1.0, "asp__L_e": 1.0}, "id": "ASNNe", "gene_reaction_rule": "YLR157C or YLR160C or YLR155C or YLR158C"}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Asparagine synthase (glutamine-hydrolysing)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASNS1"]}, "metabolites": {"asn__L_c": 1.0, "atp_c": -1.0, "asp__L_c": -1.0, "ppi_c": 1.0, "h2o_c": -1.0, "h_c": 1.0, "amp_c": 1.0, "glu__L_c": 1.0, "gln__L_c": -1.0}, "id": "ASNS1", "gene_reaction_rule": "YML096W or YGR124W or YPR145W"}, {"subsystem": "Asparagine metabolism", "name": "Asparaginyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASNTRS"]}, "metabolites": {"trnaasn_c": -1.0, "atp_c": -1.0, "asn__L_c": -1.0, "amp_c": 1.0, "asntrna_c": 1.0, "ppi_c": 1.0}, "id": "ASNTRS", "gene_reaction_rule": "YHR019C"}, {"subsystem": "Asparagine metabolism", "name": "Asparaginyl tRNA synthetase miotchondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASNTRSm"]}, "metabolites": {"asn__L_m": -1.0, "atp_m": -1.0, "trnaasn_m": -1.0, "asntrna_m": 1.0, "ppi_m": 1.0, "amp_m": 1.0}, "id": "ASNTRSm", "gene_reaction_rule": "YCR024C"}, {"subsystem": "Transport, Mitochondrial", "name": "Asparagine mitochondrial transport via proton transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ASNt2m"]}, "metabolites": {"asn__L_c": -1.0, "h_m": 1.0, "asn__L_m": 1.0, "h_c": -1.0}, "id": "ASNt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L asparagine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ASNt2r"]}, "metabolites": {"asn__L_c": 1.0, "h_e": -1.0, "asn__L_e": -1.0, "h_c": 1.0}, "id": "ASNt2r", "gene_reaction_rule": "YPL265W or YKR039W or YDR508C or YCL025C"}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Aspartate 1-decarboxylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASP1DC"]}, "metabolites": {"asp__L_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "ala_B_c": 1.0}, "id": "ASP1DC", "gene_reaction_rule": ""}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "ASPCTn", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASPCTn"]}, "metabolites": {"h_n": 1.0, "cbp_n": -1.0, "cbasp_n": 1.0, "pi_n": 1.0, "asp__L_n": -1.0}, "id": "ASPCTn", "gene_reaction_rule": "YJL130C"}, {"subsystem": "Transport, Peroxisomal", "name": "Aspartate glutamate peroxisomal shuttle", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ASPGLUtp"]}, "metabolites": {"asp__L_c": -1.0, "glu__L_x": -1.0, "glu__L_c": 1.0, "asp__L_x": 1.0}, "id": "ASPGLUtp", "gene_reaction_rule": ""}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Aspartate kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASPKi"]}, "metabolites": {"asp__L_c": -1.0, "4pasp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "ASPK", "gene_reaction_rule": "YER052C"}, {"subsystem": "Folate Metabolism", "name": "ASPOcm", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASPOcm"]}, "metabolites": {"asp__L_c": -1.0, "fad_m": -1.0, "iasp_c": 1.0, "fadh2_m": 1.0}, "id": "ASPOcm_1", "gene_reaction_rule": ""}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Aspartate transaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ASPTA"]}, "metabolites": {"asp__L_c": -1.0, "akg_c": -1.0, "glu__L_c": 1.0, "oaa_c": 1.0}, "id": "ASPTA", "gene_reaction_rule": "YLR027C"}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Aspartate transaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ASPTAm"]}, "metabolites": {"oaa_m": 1.0, "glu__L_m": 1.0, "asp__L_m": -1.0, "akg_m": -1.0}, "id": "ASPTAm", "gene_reaction_rule": "YKL106W"}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Aspartate transaminase peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ASPTAp"]}, "metabolites": {"glu__L_x": 1.0, "akg_x": -1.0, "oaa_x": 1.0, "asp__L_x": -1.0}, "id": "ASPTAp", "gene_reaction_rule": "YLR027C"}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Aspartyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASPTRS"]}, "metabolites": {"asptrna_c": 1.0, "atp_c": -1.0, "asp__L_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "trnaasp_c": -1.0}, "id": "ASPTRS", "gene_reaction_rule": "YLL018C"}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Aspartyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ASPTRSm"]}, "metabolites": {"ppi_m": 1.0, "asp__L_m": -1.0, "atp_m": -1.0, "asptrna_m": 1.0, "trnaasp_m": -1.0, "amp_m": 1.0}, "id": "ASPTRSm", "gene_reaction_rule": "YPL104W"}, {"subsystem": "Transport, Mitochondrial", "name": "Aspartate mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ASPt2m"]}, "metabolites": {"asp__L_c": -1.0, "h_m": 1.0, "h_c": -1.0, "asp__L_m": 1.0}, "id": "ASPt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "Aspartate nuclear transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ASPt2n"]}, "metabolites": {"asp__L_c": -1.0, "h_n": 1.0, "h_c": -1.0, "asp__L_n": 1.0}, "id": "ASPt2n", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L aspartate reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ASPt2r"]}, "metabolites": {"asp__L_c": 1.0, "h_e": -1.0, "h_c": 1.0, "asp__L_e": -1.0}, "id": "ASPt2r", "gene_reaction_rule": "YFL055W or YPL265W or YKR039W"}, {"subsystem": "Transport, Peroxisomal", "name": "AMPATP transporter peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATP2tp_H"]}, "metabolites": {"atp_c": -1.0, "amp_x": -1.0, "h_x": -1.0, "h_c": 1.0, "atp_x": 1.0, "amp_c": 1.0}, "id": "ATP2tp_H", "gene_reaction_rule": "YPR128C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "ATP adenylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPATF1"]}, "metabolites": {"ap4a_c": 1.0, "pi_c": 1.0, "h_c": -1.0, "adp_c": -1.0, "atp_c": -1.0}, "id": "ATPATF1", "gene_reaction_rule": "YDR530C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "ATP adenylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPATF2"]}, "metabolites": {"ap4g_c": 1.0, "pi_c": 1.0, "gtp_c": -1.0, "h_c": -1.0, "adp_c": -1.0}, "id": "ATPATF2", "gene_reaction_rule": "YCL050C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "ATP adenylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPATF3"]}, "metabolites": {"gdp_c": -1.0, "gp4g_c": 1.0, "pi_c": 1.0, "gtp_c": -1.0, "h_c": -1.0}, "id": "ATPATF3", "gene_reaction_rule": "YCL050C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "ATP maintenance requirement", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPM"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "ATPM", "gene_reaction_rule": ""}, {"subsystem": "Starch and Sucrose Metabolism", "name": "Endo 1 3 beta glucan glucohydrase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["13BGH"]}, "metabolites": {"13BDglcn_c": -1.0, "glc__D_c": 1.0, "h2o_c": -1.0}, "id": "13BGH", "gene_reaction_rule": "YGR282C"}, {"subsystem": "Starch and Sucrose Metabolism", "name": "Exo 1 3 beta glucan glucohydrase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["13BGHe"]}, "metabolites": {"h2o_e": -1.0, "13BDglcn_e": -1.0, "glc__D_e": 1.0}, "id": "13BGHe", "gene_reaction_rule": "YOR190W or YDR261C or YLR300W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "1 3 beta glucan synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["13GS"]}, "metabolites": {"13BDglcn_c": 1.0, "udp_c": 1.0, "udpg_c": -1.0, "h_c": 1.0}, "id": "13GS", "gene_reaction_rule": "(YCR034W and YGR032W) or (YCR034W and YLR342W) or (YCR034W and YMR306W)"}, {"subsystem": "Transport, Mitochondrial", "name": "2 Dehydro 3 deoxy D arabino heptonate7 phohsphate mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["2DDA7Ptm"]}, "metabolites": {"2dda7p_m": 1.0, "2dda7p_c": -1.0}, "id": "2DDA7Ptm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "2 Dehydropantoate mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["2DHPtm"]}, "metabolites": {"2dhp_m": 1.0, "2dhp_c": -1.0}, "id": "2DHPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "2MCITtm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["2MCITtm"]}, "metabolites": {"2mcit_c": -1.0, "2mcit_m": 1.0}, "id": "2MCITtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "2OHPH 5tn", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["2OHPH_5tn"]}, "metabolites": {"2ohph_5_n": 1.0, "2ohph_5_c": -1.0}, "id": "2OHPH_5tn", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "2OMPH 5tm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["2OMPH_5tm"]}, "metabolites": {"2omph_5_c": -1.0, "2omph_5_m": 1.0}, "id": "2OMPH_5tm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "2OMPH 5tn", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["2OMPH_5tn"]}, "metabolites": {"2omph_5_c": -1.0, "2omph_5_n": 1.0}, "id": "2OMPH_5tn", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "2 oxoadipate transport out of mitochondria via diffusion", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["2OXOADPtim"]}, "metabolites": {"2oxoadp_m": -1.0, "2oxoadp_c": 1.0}, "id": "2OXOADPtim", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "4 Hydroxyphenylpyruvateoxygen oxidoreductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["34HPPOR"]}, "metabolites": {"o2_c": -1.0, "34hpp_c": -1.0, "co2_c": 1.0, "hgentis_c": 1.0}, "id": "34HPPOR", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "3 4 hydroxyphenyl pyruvate mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["34HPPt2m"]}, "metabolites": {"34hpp_c": -1.0, "h_m": 1.0, "34hpp_m": 1.0, "h_c": -1.0}, "id": "34HPPt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "3 4 hydroxyphenyl pyruvate peroxisomal transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["34HPPt2p"]}, "metabolites": {"34hpp_x": 1.0, "34hpp_c": -1.0, "h_c": -1.0, "h_x": 1.0}, "id": "34HPPt2p", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "2 Isopropylmalate transport diffusion mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["3C3HMPtm"]}, "metabolites": {"3c3hmp_m": 1.0, "3c3hmp_c": -1.0}, "id": "3C3HMPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "3 Carboxy 4 methyl 2 oxopentanoate transport diffusion mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["3C4MOPtm"]}, "metabolites": {"3c4mop_c": -1.0, "3c4mop_m": 1.0}, "id": "3C4MOPtm", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid Metabolism", "name": "3 Dehydrosphinganine reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["3DSPHR"]}, "metabolites": {"3dsphgn_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "sphgn_c": 1.0}, "id": "3DSPHR", "gene_reaction_rule": "YBR265W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "3 hydroxyanthranilate 3 4 dioxygenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["3HAO"]}, "metabolites": {"3hanthrn_c": -1.0, "o2_c": -1.0, "cmusa_c": 1.0, "h_c": 1.0}, "id": "3HAO", "gene_reaction_rule": "YJR025C"}, {"subsystem": "Transport, Mitochondrial", "name": "3 methyl 2 oxobutanoate transport diffusion mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["3MOBtm"]}, "metabolites": {"3mob_m": 1.0, "3mob_c": -1.0}, "id": "3MOBtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "3 Methyl 2 oxopentanoate transport diffusion mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["3MOPtm"]}, "metabolites": {"3mop_c": -1.0, "3mop_m": 1.0}, "id": "3MOPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "3 Octaprenyl 4 hydroxybenzoate mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["3OPHB_5tm"]}, "metabolites": {"3ophb_5_m": 1.0, "3ophb_5_c": -1.0}, "id": "3OPHB_5tm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "4 aminobutanal mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["4ABUTNtm"]}, "metabolites": {"4abutn_m": 1.0, "4abutn_c": -1.0}, "id": "4ABUTNtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "4 aminobutanoate mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["4ABUTtm"]}, "metabolites": {"4abut_m": 1.0, "4abut_c": -1.0}, "id": "4ABUTtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "4 Aminobenzoate mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["4ABZtm"]}, "metabolites": {"4abz_m": 1.0, "4abz_c": -1.0}, "id": "4ABZtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "4 hydroxy 2 oxoglutarate mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["4H2OGLTtm"]}, "metabolites": {"4h2oglt_m": 1.0, "4h2oglt_c": -1.0}, "id": "4H2OGLTtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "4 hydroxy 2 oxoglutarate peroxisomal transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["4H2OGLTtp"]}, "metabolites": {"4h2oglt_x": 1.0, "4h2oglt_c": -1.0}, "id": "4H2OGLTtp", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "4 Hydroxybenzoate mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["4HBZtm"]}, "metabolites": {"4hbz_c": -1.0, "4hbz_m": 1.0}, "id": "4HBZtm", "gene_reaction_rule": ""}, {"subsystem": "Arginine and Proline Metabolism", "name": "L 4 hydroxyglutamate semialdehyde dehydrogenase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["4HGLSDm"]}, "metabolites": {"4hglusa_m": -1.0, "h2o_m": -1.0, "e4hglu_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0}, "id": "4HGLSDm", "gene_reaction_rule": "YHR037W"}, {"subsystem": "Transport, Mitochondrial", "name": "Trans 4 hydroxy L proline mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["4HPRO_LTtm"]}, "metabolites": {"4hpro_LT_m": 1.0, "4hpro_LT_c": -1.0}, "id": "4HPRO_LTtm", "gene_reaction_rule": ""}, {"subsystem": "Threonine and Lysine Metabolism", "name": "4-Hydroxy-L-threonine synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["4HTHRS"]}, "metabolites": {"h2o_c": -1.0, "phthr_c": -1.0, "pi_c": 1.0, "4hthr_c": 1.0}, "id": "4HTHRS", "gene_reaction_rule": "YCR053W"}, {"subsystem": "Transport, Extracellular", "name": "5 Aminolevulinate transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["5AOPt2"]}, "metabolites": {"5aop_c": 1.0, "h_e": -1.0, "5aop_e": -1.0, "h_c": 1.0}, "id": "5AOPt2", "gene_reaction_rule": "YDL210W"}, {"subsystem": "Transport, Mitochondrial", "name": "5 Aminolevulinate mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["5AOPtm"]}, "metabolites": {"5aop_c": -1.0, "5aop_m": 1.0}, "id": "5AOPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "5MTHFtm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["5MTHFtm"]}, "metabolites": {"5mthf_m": 1.0, "5mthf_c": -1.0}, "id": "5MTHFtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Endoplasmic Reticular", "name": "6 phospho D glucono 1 5 lactone endoplasmic reticular transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["6PGLter"]}, "metabolites": {"6pgl_r": 1.0, "6pgl_c": -1.0}, "id": "6PGLter", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "8 Amino 7 oxononanoate reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["8AONNt2"]}, "metabolites": {"8aonn_c": 1.0, "h_e": -1.0, "h_c": 1.0, "8aonn_e": -1.0}, "id": "8AONNt2", "gene_reaction_rule": ""}, {"subsystem": "Other Amino Acid Metabolism", "name": "4 acetamidobutyrate deacetylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AABTN"]}, "metabolites": {"ac_c": 1.0, "4aabutn_c": -1.0, "h2o_c": -1.0, "4abut_c": 1.0}, "id": "AABTN", "gene_reaction_rule": ""}, {"subsystem": "Threonine and Lysine Metabolism", "name": "L aminoadipate semialdehyde dehydrogenase NADPH ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AASAD1"]}, "metabolites": {"nadp_c": 1.0, "nadph_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "L2aadp_c": -1.0, "amp_c": 1.0, "L2aadp6sa_c": 1.0, "h_c": -1.0}, "id": "AASAD1", "gene_reaction_rule": "YBR115C and YGL154C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "L aminoadipate semialdehyde dehydrogenase NADH ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AASAD2"]}, "metabolites": {"L2aadp6sa_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "L2aadp_c": -1.0, "h_c": -1.0, "nad_c": 1.0, "nadh_c": -1.0, "amp_c": 1.0}, "id": "AASAD2", "gene_reaction_rule": "YBR115C and YGL154C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "2 aminoadipate transaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AATA"]}, "metabolites": {"akg_c": 1.0, "L2aadp_c": 1.0, "2oxoadp_c": -1.0, "glu__L_c": -1.0}, "id": "AATA", "gene_reaction_rule": ""}, {"subsystem": "Glutamate metabolism", "name": "4-aminobutyrate transaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ABTA"]}, "metabolites": {"akg_c": -1.0, "glu__L_c": 1.0, "sucsal_c": 1.0, "4abut_c": -1.0}, "id": "ABTA", "gene_reaction_rule": "YGR019W"}, {"subsystem": "Transport, Extracellular", "name": "L arabinitol transport via passive diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ABTt"]}, "metabolites": {"abt_c": 1.0, "abt_e": -1.0}, "id": "ABTt", "gene_reaction_rule": ""}, {"subsystem": "Other Amino Acid Metabolism", "name": "Aminobutyraldehyde dehydrogenase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ABUTDm"]}, "metabolites": {"4abutn_m": -1.0, "4abut_m": 1.0, "h2o_m": -1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0}, "id": "ABUTDm", "gene_reaction_rule": "YOR374W or YER073W"}, {"subsystem": "Transport, Extracellular", "name": "4 aminobutyrate reversible transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ABUTt2"]}, "metabolites": {"4abut_e": -1.0, "h_e": -1.0, "h_c": 1.0, "4abut_c": 1.0}, "id": "ABUTt2r", "gene_reaction_rule": "YOR348C or YDL210W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Acetyl-CoA C-acetyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACACT1"]}, "metabolites": {"aacoa_c": 1.0, "coa_c": 1.0, "accoa_c": -2.0}, "id": "ACACT1r", "gene_reaction_rule": "YPL028W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Acetyl CoA C acetyltransferase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACACT1m"]}, "metabolites": {"accoa_m": -2.0, "coa_m": 1.0, "aacoa_m": 1.0}, "id": "ACACT1m", "gene_reaction_rule": "YPL028W"}, {"subsystem": "Fatty Acid Degradation", "name": "Acetyl CoA C acetyltransferase octanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACACT4p"]}, "metabolites": {"3odcoa_x": -1.0, "occoa_x": 1.0, "accoa_x": 1.0, "coa_x": -1.0}, "id": "ACACT4p", "gene_reaction_rule": "YIL160C"}, {"subsystem": "Fatty Acid Degradation", "name": "Acetyl CoA C acyltransferase decanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACACT5p"]}, "metabolites": {"3oddcoa_x": -1.0, "accoa_x": 1.0, "dcacoa_x": 1.0, "coa_x": -1.0}, "id": "ACACT5p", "gene_reaction_rule": "YIL160C"}, {"subsystem": "Fatty Acid Degradation", "name": "Acetyl CoA C acetyltransferase dodecanoyl peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACACT6p"]}, "metabolites": {"3otdcoa_x": -1.0, "ddcacoa_x": 1.0, "accoa_x": 1.0, "coa_x": -1.0}, "id": "ACACT6p", "gene_reaction_rule": "YIL160C"}, {"subsystem": "Fatty Acid Degradation", "name": "Acetyl CoA acyltransferase tetradecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACACT7p"]}, "metabolites": {"accoa_x": 1.0, "tdcoa_x": 1.0, "3ohdcoa_x": -1.0, "coa_x": -1.0}, "id": "ACACT7p", "gene_reaction_rule": "YIL160C"}, {"subsystem": "Fatty Acid Degradation", "name": "Acetyl CoA acyltransferase hexadecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACACT8p"]}, "metabolites": {"accoa_x": 1.0, "pmtcoa_x": 1.0, "3ohodcoa_x": -1.0, "coa_x": -1.0}, "id": "ACACT8p", "gene_reaction_rule": "YIL160C"}, {"subsystem": "Fatty Acid Degradation", "name": "Acetyl CoA acyltransferase tetracosanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ACACT9p"]}, "metabolites": {"3ohxccoa_x": -1.0, "ttccoa_x": 1.0, "accoa_x": 1.0, "coa_x": -1.0}, "id": "ACACT9p", "gene_reaction_rule": "YIL160C"}, {"subsystem": "Transport, Extracellular", "name": "Acetaldehyde reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACALDt"]}, "metabolites": {"acald_c": 1.0, "acald_e": -1.0}, "id": "ACALDt", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Acetyl-CoA carboxylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACCOACr"]}, "metabolites": {"malcoa_c": 1.0, "accoa_c": -1.0, "atp_c": -1.0, "hco3_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "ACCOAC", "gene_reaction_rule": "YNR016C"}, {"subsystem": "Glutamate metabolism", "name": "N acetylglucosamine 6 phosphate synthase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ACGAM6PS"]}, "metabolites": {"acgam6p_c": 1.0, "gam6p_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "accoa_c": -1.0}, "id": "ACGAM6PS", "gene_reaction_rule": "YFL017C"}, {"name": "Adenine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ade_LPAREN_e_RPAREN_"]}, "metabolites": {"ade_e": -1.0}, "id": "EX_ade_e", "gene_reaction_rule": ""}, {"subsystem": "Phospholipid Biosynthesis", "name": "1 Acyl glycerol 3 phosphate acyltransferase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AGAT_SC"]}, "metabolites": {"hdcoa_c": -0.17, "pa_SC_c": 0.01, "ddcacoa_c": -0.06, "pmtcoa_c": -0.27, "stcoa_c": -0.05, "odecoa_c": -0.24, "coa_c": 1.0, "1ag3p_SC_c": -0.01, "ocdycacoa_c": -0.09, "dcacoa_c": -0.02, "tdcoa_c": -0.1}, "id": "AGAT_SC", "gene_reaction_rule": "YDL052C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "N acetyl g glutamyl phosphate reductase irreversible mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AGPRim"]}, "metabolites": {"acg5sa_m": 1.0, "acg5p_m": -1.0, "nadph_m": -1.0, "nadp_m": 1.0, "pi_m": 1.0, "h_m": -1.0}, "id": "AGPRim", "gene_reaction_rule": "YER069W"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Alanine glyoxylate aminotransferase irreversible ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AGT"]}, "metabolites": {"glx_c": -1.0, "pyr_c": 1.0, "ala__L_c": -1.0, "gly_c": 1.0}, "id": "AGTi", "gene_reaction_rule": "YFL030W"}, {"subsystem": "Transport, Mitochondrial", "name": "S adenosyl L homocysteine reversible transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AHCYStm"]}, "metabolites": {"ahcys_c": -1.0, "ahcys_m": 1.0}, "id": "AHCYStm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "AHCYStn", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AHCYStn"]}, "metabolites": {"ahcys_c": -1.0, "ahcys_n": 1.0}, "id": "AHCYStn", "gene_reaction_rule": ""}, {"subsystem": "Methionine Metabolism", "name": "Adenosylhomocysteinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AHCi"]}, "metabolites": {"hcys__L_c": 1.0, "h2o_c": -1.0, "ahcys_c": -1.0, "adn_c": 1.0}, "id": "AHCi", "gene_reaction_rule": "YER043C"}, {"subsystem": "Thiamine Metabolism", "name": "4 amino 5 hydroxymethyl 2 methylpyrimidine synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AHMMPS"]}, "metabolites": {"4ahmmp_c": 1.0, "pi_c": 1.0, "h_c": -2.0, "gcald_c": 1.0, "air_c": -1.0}, "id": "AHMMPS", "gene_reaction_rule": ""}, {"subsystem": "Methionine Metabolism", "name": "O acetylhomoserine thiol lyase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AHSERL"]}, "metabolites": {"ch4s_c": -1.0, "ac_c": 1.0, "h_c": 1.0, "met__L_c": 1.0, "achms_c": -1.0}, "id": "AHSERL", "gene_reaction_rule": "YLR303W"}, {"subsystem": "Methionine Metabolism", "name": "O acetylhomoserine thiol lyase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AHSERL2"]}, "metabolites": {"hcys__L_c": 1.0, "ac_c": 1.0, "h_c": 1.0, "h2s_c": -1.0, "achms_c": -1.0}, "id": "AHSERL2", "gene_reaction_rule": "YLR303W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Phosphoribosylaminoimidazolecarboxamide formyltransferase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AICART"]}, "metabolites": {"aicar_c": -1.0, "fprica_c": 1.0, "thf_c": 1.0, "10fthf_c": -1.0}, "id": "AICART", "gene_reaction_rule": "YLR028C or YMR120C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Phosphoribosylaminoimidazole carboxylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AIRCr"]}, "metabolites": {"co2_c": -1.0, "5aizc_c": 1.0, "h_c": 1.0, "air_c": -1.0}, "id": "AIRCr", "gene_reaction_rule": "YOR128C"}, {"subsystem": "Citric Acid Cycle", "name": "Oxoglutarate dehydrogenase lipoamide ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AKGDam"]}, "metabolites": {"lpam_m": -1.0, "h_m": -1.0, "co2_m": 1.0, "akg_m": -1.0, "sdhlam_m": 1.0}, "id": "AKGDam", "gene_reaction_rule": "YIL125W and YFL018C and YDR148C"}, {"subsystem": "Citric Acid Cycle", "name": "Oxoglutarate dehydrogenase dihydrolipoamide S succinyltransferase ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AKGDbm"]}, "metabolites": {"coa_m": -1.0, "succoa_m": 1.0, "dhlam_m": 1.0, "sdhlam_m": -1.0}, "id": "AKGDbm", "gene_reaction_rule": "YIL125W and YFL018C and YDR148C"}, {"subsystem": "Transport, Extracellular", "name": "Alpha ketoglutaratemalate transporter", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AKGMAL"]}, "metabolites": {"akg_c": -1.0, "mal__L_c": 1.0, "mal__L_e": -1.0, "akg_e": 1.0}, "id": "AKGMAL", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "2 oxoglutarate nuclear transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AKGt2n"]}, "metabolites": {"h_n": 1.0, "akg_c": -1.0, "h_c": -1.0, "akg_n": 1.0}, "id": "AKGt2n", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "2 oxoglutarate reversible transport via symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AKGt2r"]}, "metabolites": {"akg_c": 1.0, "h_e": -1.0, "h_c": 1.0, "akg_e": -1.0}, "id": "AKGt2r", "gene_reaction_rule": ""}, {"subsystem": "Folate Metabolism", "name": "Alkaline phosphatase Dihydroneopterin ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AKP1"]}, "metabolites": {"dhnpt_c": 1.0, "h2o_c": -3.0, "pi_c": 3.0, "h_c": 2.0, "ahdt_c": -1.0}, "id": "AKP1", "gene_reaction_rule": "YDR481C"}, {"subsystem": "Porphyrin and Chlorophyll Metabolism", "name": "5 aminolevulinate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALASm"]}, "metabolites": {"succoa_m": -1.0, "gly_m": -1.0, "co2_m": 1.0, "coa_m": 1.0, "h_m": -1.0, "5aop_m": 1.0}, "id": "ALASm", "gene_reaction_rule": "YDR232W"}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "L-alanine transaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ALATA_L"]}, "metabolites": {"akg_c": -1.0, "pyr_c": 1.0, "ala__L_c": -1.0, "glu__L_c": 1.0}, "id": "ALATA_L", "gene_reaction_rule": "YDR111C"}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "L alanine transaminase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ALATA_Lm"]}, "metabolites": {"glu__L_m": 1.0, "ala__L_m": -1.0, "pyr_m": 1.0, "akg_m": -1.0}, "id": "ALATA_Lm", "gene_reaction_rule": "YLR089C"}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Alanyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALATRS"]}, "metabolites": {"trnaala_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "ala__L_c": -1.0, "amp_c": 1.0, "alatrna_c": 1.0}, "id": "ALATRS", "gene_reaction_rule": "YOR335C"}, {"subsystem": "Transport, Extracellular", "name": "L alanine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ALAt2r"]}, "metabolites": {"ala__L_e": -1.0, "h_e": -1.0, "ala__L_c": 1.0, "h_c": 1.0}, "id": "ALAt2r", "gene_reaction_rule": "YOL020W or YKR039W or YCL025C or YPL265W or YOR348C"}, {"subsystem": "Glycerolipid Metabolism", "name": "Alcohol dehydrogenase glycerol NADP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALCD19y"]}, "metabolites": {"glyc_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "glyald_c": -1.0}, "id": "ALCD19y", "gene_reaction_rule": "YHR104W"}, {"subsystem": "Glycerolipid Metabolism", "name": "ALCD2m", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ALCD2m"]}, "metabolites": {"nad_m": -1.0, "etoh_m": -1.0, "h_m": 1.0, "nadh_m": 1.0, "acald_m": 1.0}, "id": "ALCD2m", "gene_reaction_rule": "YMR083W"}, {"subsystem": "Pyruvate Metabolism", "name": "Alcohol dehydrogenase (ethanol)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ALCD2x"]}, "metabolites": {"acald_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0, "h_c": 1.0, "etoh_c": -1.0}, "id": "ALCD2x", "gene_reaction_rule": "YDL168W or YBR145W or YMR303C or YOL086C or YGL256W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Aldehyde dehydrogenase (phenylacetaldehyde, NAD)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALDD19x"]}, "metabolites": {"h2o_c": -1.0, "pac_c": 1.0, "h_c": 2.0, "nad_c": -1.0, "pacald_c": -1.0, "nadh_c": 1.0}, "id": "ALDD19xr", "gene_reaction_rule": "YMR170C or YMR169C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Aldehyde dehydrogenase indole 3 acetaldehyde NAD mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALDD20xm"]}, "metabolites": {"h2o_m": -1.0, "id3acald_m": -1.0, "ind3ac_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0}, "id": "ALDD20xm", "gene_reaction_rule": "YOR374W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Aldehyde dehydrogenase indole 3 acetaldehyde NADP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALDD20y"]}, "metabolites": {"h2o_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "h_c": 2.0, "ind3ac_c": 1.0, "id3acald_c": -1.0}, "id": "ALDD20y", "gene_reaction_rule": "YPL061W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Aldehyde dehydrogenase indole 3 acetaldehyde NADP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALDD20ym"]}, "metabolites": {"nadph_m": 1.0, "h2o_m": -1.0, "nadp_m": -1.0, "id3acald_m": -1.0, "ind3ac_m": 1.0, "h_m": 2.0}, "id": "ALDD20ym", "gene_reaction_rule": "YER073W or YOR374W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Aldehyde dehydrogenase acetylaldehyde NAD mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALDD2xm"]}, "metabolites": {"acald_m": -1.0, "h2o_m": -1.0, "ac_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0}, "id": "ALDD2xm", "gene_reaction_rule": "YOR374W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Aldehyde dehydrogenase (acetaldehyde, NADP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALDD2y"]}, "metabolites": {"h2o_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "acald_c": -1.0, "h_c": 2.0, "ac_c": 1.0}, "id": "ALDD2y", "gene_reaction_rule": "YPL061W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Aldehyde dehydrogenase acetylaldehyde NADP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALDD2ym"]}, "metabolites": {"acald_m": -1.0, "nadph_m": 1.0, "h2o_m": -1.0, "nadp_m": -1.0, "ac_m": 1.0, "h_m": 2.0}, "id": "ALDD2ym", "gene_reaction_rule": "YOR374W"}, {"subsystem": "Histidine Metabolism", "name": "Allantoate amidinohydrolase reversible", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ALLTAHr"]}, "metabolites": {"alltt_c": -1.0, "urdglyc_c": 1.0, "h2o_c": -1.0, "urea_c": 1.0}, "id": "ALLTAHr", "gene_reaction_rule": "YIR029W"}, {"subsystem": "Histidine Metabolism", "name": "Allantoinase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ALLTNr"]}, "metabolites": {"alltt_c": 1.0, "h2o_c": -1.0, "h_c": 1.0, "alltn_c": -1.0}, "id": "ALLTN", "gene_reaction_rule": "YIR027C"}, {"subsystem": "Transport, Extracellular", "name": "Allantoin irreversible uniport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALLTNti"]}, "metabolites": {"alltn_e": -1.0, "alltn_c": 1.0}, "id": "ALLTNti", "gene_reaction_rule": "YIR028W"}, {"subsystem": "Transport, Extracellular", "name": "Allantoate irreversible uniport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALLTTti"]}, "metabolites": {"alltt_c": 1.0, "alltt_e": -1.0}, "id": "ALLTTti", "gene_reaction_rule": "YJR152W"}, {"subsystem": "Nitrogen Metabolism", "name": "Allophanate hydrolase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ALPHNH"]}, "metabolites": {"h2o_c": -1.0, "allphn_c": -1.0, "co2_c": 2.0, "h_c": -3.0, "nh4_c": 2.0}, "id": "ALPHNH", "gene_reaction_rule": "YBR208C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "AM6SAD", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AM6SAD"]}, "metabolites": {"h2o_c": -1.0, "amuco_c": 1.0, "am6sa_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "AM6SAD", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Adenosylmethionine-8-amino-7-oxononanoate transaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AMAOTr"]}, "metabolites": {"8aonn_c": -1.0, "amet_c": -1.0, "dann_c": 1.0, "amob_c": 1.0}, "id": "AMAOTr", "gene_reaction_rule": "YNR058W"}, {"subsystem": "Transport, Extracellular", "name": "S adenosyl L methionine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AMETt2"]}, "metabolites": {"amet_c": 1.0, "h_e": -1.0, "h_c": 1.0, "amet_e": -1.0}, "id": "AMETt2", "gene_reaction_rule": "YPL274W"}, {"subsystem": "Transport, Mitochondrial", "name": "S Adenosyl L methionine reversible transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AMETtm"]}, "metabolites": {"amet_c": -1.0, "amet_m": 1.0}, "id": "AMETtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "AMETtn", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["AMETtn"]}, "metabolites": {"amet_c": -1.0, "amet_n": 1.0}, "id": "AMETtn", "gene_reaction_rule": ""}, {"subsystem": "Arginine and Proline Metabolism", "name": "Amidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AMID"]}, "metabolites": {"4gudbd_c": -1.0, "h2o_c": -1.0, "nh4_c": 1.0, "4gudbutn_c": 1.0}, "id": "AMID", "gene_reaction_rule": "YDR242W or YMR293C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Amidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AMID2"]}, "metabolites": {"pad_c": -1.0, "h2o_c": -1.0, "pac_c": 1.0, "nh4_c": 1.0}, "id": "AMID2", "gene_reaction_rule": "YDR242W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Amidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AMID3"]}, "metabolites": {"h2o_c": -1.0, "ind3ac_c": 1.0, "iad_c": -1.0, "nh4_c": 1.0}, "id": "AMID3", "gene_reaction_rule": "YDR242W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Adenosine monophosphate deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["AMPDA"]}, "metabolites": {"h2o_c": -1.0, "nh4_c": 1.0, "h_c": -1.0, "imp_c": 1.0, "amp_c": -1.0}, "id": "AMPDA", "gene_reaction_rule": "YML035C"}, {"name": "Adenosine exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_adn_LPAREN_e_RPAREN_"]}, "metabolites": {"adn_e": -1.0}, "id": "EX_adn_e", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "ATPase cytosolic", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPS"]}, "metabolites": {"h2o_c": -1.0, "h_e": 1.0, "adp_c": 1.0, "atp_c": -1.0, "pi_c": 1.0}, "id": "ATPS", "gene_reaction_rule": "(YPL036W and YCR024C_A and YEL017C_A) or (YGL008C and YCR024C_A and YEL017C_A)"}, {"subsystem": "Oxidative Phosphorylation", "name": "ATP synthase Golgi Apparatus", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPS3g"]}, "metabolites": {"atp_g": 1.0, "h2o_g": 1.0, "h_g": 2.0, "adp_g": -1.0, "h_c": -3.0, "pi_g": -1.0}, "id": "ATPS3g", "gene_reaction_rule": "YBR127C and YPL234C and YDL185W and YOR332W and YLR447C and YEL051W and YKL080W and YHR039C_A and YHR026W and YMR054W and YEL027W and YPR036W and YGR020C"}, {"subsystem": "Oxidative Phosphorylation", "name": "ATP synthase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPS3m"]}, "metabolites": {"atp_m": 1.0, "h2o_m": 1.0, "pi_m": -1.0, "adp_m": -1.0, "h_m": 2.0, "h_c": -3.0}, "id": "ATPS3m", "gene_reaction_rule": "(YDL004W and YKL016C and Q0085 and YPL078C and Q0130 and YDR377W and YPL271W and YML081C_A and YLR295C and YBR039W and YJR121W and YDR298C and Q0080 and YDL181W and YBL099W) or (YDL004W and YML081C_A and YLR295C and YJR121W and YOL077W_A and YPR020W and YDR298C and YDR322C_A and YKL016C and Q0085 and YPL271W and YDR377W and Q0130 and YPL078C and YBR039W and YDL181W and Q0080 and YBL099W)"}, {"subsystem": "Oxidative Phosphorylation", "name": "ATP synthase vacuole", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPS3v"]}, "metabolites": {"h_v": 2.0, "adp_v": -1.0, "pi_v": -1.0, "atp_v": 1.0, "h_c": -3.0, "h2o_v": 1.0}, "id": "ATPS3v", "gene_reaction_rule": "YBR127C and YPL234C and YDL185W and YOR270C and YOR332W and YLR447C and YEL051W and YKL080W and YHR039C_A and YHR026W and YEL027W and YPR036W and YGR020C"}, {"subsystem": "Transport, Mitochondrial", "name": "ADPATP transporter mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPtm_H"]}, "metabolites": {"atp_c": 1.0, "atp_m": -1.0, "h_c": -1.0, "adp_c": -1.0, "adp_m": 1.0, "h_m": 1.0}, "id": "ATPtm_H", "gene_reaction_rule": "YBR085W or YMR056C or YBL030C"}, {"subsystem": "Transport, Peroxisomal", "name": "ADPATP transporter peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ATPtp_H"]}, "metabolites": {"atp_c": -1.0, "adp_x": -1.0, "h_x": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_x": 1.0}, "id": "ATPtp_H", "gene_reaction_rule": "YPR128C"}, {"subsystem": "Cysteine Metabolism", "name": "3',5'-bisphosphate nucleotidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["BPNT"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pap_c": -1.0, "amp_c": 1.0}, "id": "BPNT", "gene_reaction_rule": "YOL064C"}, {"subsystem": "Transport, Extracellular", "name": "Biotin uptake", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["BTNt2i"]}, "metabolites": {"btn_c": 1.0, "h_e": -1.0, "h_c": 1.0, "btn_e": -1.0}, "id": "BTNt2i", "gene_reaction_rule": "YGR065C or YNR056C"}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Biotin synthase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["BTSr"]}, "metabolites": {"s_c": -1.0, "btn_c": 1.0, "h_c": 2.0, "dtbt_c": -1.0}, "id": "BTSr", "gene_reaction_rule": "YGR286C"}, {"subsystem": "Sterol Biosynthesis", "name": "C 14 sterol reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C14STR"]}, "metabolites": {"44mctr_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "44mzym_c": 1.0}, "id": "C14STR", "gene_reaction_rule": "YNL280C"}, {"subsystem": "Sterol Biosynthesis", "name": "C 22 sterol desaturase NADP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C22STDS"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "ergtrol_c": -1.0, "ergtetrol_c": 1.0}, "id": "C22STDS", "gene_reaction_rule": "YMR015C"}, {"subsystem": "Sterol Biosynthesis", "name": "C s24 sterol reductase endoplamic reticular", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C24STRer"]}, "metabolites": {"nadph_r": -1.0, "nadp_r": 1.0, "h_r": -1.0, "ergtetrol_r": -1.0, "ergst_r": 1.0}, "id": "C24STRer", "gene_reaction_rule": "YGL012W"}, {"subsystem": "Sterol Biosynthesis", "name": "C 3 sterol dehydrogenase 4 methylzymosterol ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C3STDH1"]}, "metabolites": {"co2_c": 1.0, "4mzym_int1_c": -1.0, "4mzym_int2_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "C3STDH1", "gene_reaction_rule": "YGL001C"}, {"subsystem": "Sterol Biosynthesis", "name": "C 3 sterol dehydrogenase zymosterol ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C3STDH2"]}, "metabolites": {"co2_c": 1.0, "zym_int2_c": 1.0, "zym_int1_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "C3STDH2", "gene_reaction_rule": "YGL001C"}, {"subsystem": "Sterol Biosynthesis", "name": "C 3 sterol keto reductase 4 methylzymosterol ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C3STKR1"]}, "metabolites": {"4mzym_int2_c": -1.0, "nadph_c": -1.0, "h_c": -1.0, "4mzym_c": 1.0, "nadp_c": 1.0}, "id": "C3STKR1", "gene_reaction_rule": "YLR100W"}, {"subsystem": "Sterol Biosynthesis", "name": "C 3 sterol keto reductase zymosterol ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C3STKR2"]}, "metabolites": {"zym_int2_c": -1.0, "zymst_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0}, "id": "C3STKR2", "gene_reaction_rule": "YLR100W"}, {"subsystem": "Sterol Biosynthesis", "name": "C 4 sterol methyl oxidase 4 4 dimethylzymosterol ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C4STMO1"]}, "metabolites": {"o2_c": -3.0, "h2o_c": 4.0, "nadp_c": 3.0, "nadph_c": -3.0, "h_c": -3.0, "4mzym_int1_c": 1.0, "44mzym_c": -1.0}, "id": "C4STMO1", "gene_reaction_rule": "YGR060W"}, {"subsystem": "Sterol Biosynthesis", "name": "C 4 sterol methyl oxidase 4 methylzymosterol ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C4STMO2"]}, "metabolites": {"o2_c": -3.0, "h2o_c": 4.0, "nadp_c": 3.0, "nadph_c": -3.0, "zym_int1_c": 1.0, "h_c": -3.0, "4mzym_c": -1.0}, "id": "C4STMO2", "gene_reaction_rule": "YGR060W"}, {"subsystem": "Sterol Biosynthesis", "name": "C 5 sterol desaturase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C5STDS"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "nadp_c": 1.0, "nadph_c": -1.0, "epist_c": -1.0, "h_c": -1.0, "ergtrol_c": 1.0}, "id": "C5STDS", "gene_reaction_rule": "YLR056W"}, {"subsystem": "Sterol Biosynthesis", "name": "C 8 sterol isomerase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["C8STI"]}, "metabolites": {"epist_c": 1.0, "fecost_c": -1.0}, "id": "C8STI", "gene_reaction_rule": "YMR202W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Catalase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CAT"]}, "metabolites": {"h2o2_c": -2.0, "h2o_c": 2.0, "o2_c": 1.0}, "id": "CAT", "gene_reaction_rule": "YGR088W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Catalase A peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CATp"]}, "metabolites": {"h2o_x": 2.0, "h2o2_x": -2.0, "o2_x": 1.0}, "id": "CATp", "gene_reaction_rule": "YDR256C"}, {"subsystem": "Transport, Nuclear", "name": "N carbomoyl L aspartate transport diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CBASPtn"]}, "metabolites": {"cbasp_c": 1.0, "cbasp_n": -1.0}, "id": "CBASPtn", "gene_reaction_rule": ""}, {"subsystem": "Arginine and Proline Metabolism", "name": "Carbamoyl-phosphate synthase (glutamine-hydrolysing)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CBPS"]}, "metabolites": {"cbp_c": 1.0, "atp_c": -2.0, "hco3_c": -1.0, "glu__L_c": 1.0, "h2o_c": -1.0, "h_c": 2.0, "adp_c": 2.0, "pi_c": 1.0, "gln__L_c": -1.0}, "id": "CBPS", "gene_reaction_rule": "YOR303W and YJR109C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "CBPSn", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CBPSn"]}, "metabolites": {"adp_n": 2.0, "hco3_n": -1.0, "glu__L_n": 1.0, "atp_n": -2.0, "h2o_n": -1.0, "gln__L_n": -1.0, "pi_n": 1.0, "h_n": 2.0, "cbp_n": 1.0}, "id": "CBPSn", "gene_reaction_rule": "YJL130C"}, {"subsystem": "Transport, Nuclear", "name": "Carbamoyl phosphate nuclear transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CBPtn"]}, "metabolites": {"cbp_c": -1.0, "cbp_n": 1.0}, "id": "CBPtn", "gene_reaction_rule": ""}, {"subsystem": "Phospholipid Biosynthesis", "name": "CDP diacylglycerol serine O phosphatidyltransferae yeast specific mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CDPDGPm_SC"]}, "metabolites": {"cdpdag_SC_m": -0.01, "h_m": 1.0, "glyc3p_m": -1.0, "pgp_SC_m": 0.01, "cmp_m": 1.0}, "id": "CDPDGPm_SC", "gene_reaction_rule": "YCL004W"}, {"subsystem": "Transport, Nuclear", "name": "CDP nuclear transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CDPtn"]}, "metabolites": {"cdp_c": -1.0, "cdp_n": 1.0}, "id": "CDPtn", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid Metabolism", "name": "Ceramide 1 hydroxylase 24C ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CERH124", "CERS2_APOS_24"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "cer1_24_c": -1.0, "nadph_c": -1.0, "cer2_24_c": 1.0, "nadp_c": 1.0, "h_c": -1.0}, "id": "CERH124_copy1", "gene_reaction_rule": "YDR297W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Ceramide 1 hydroxylase 26C ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CERH126", "CERS2_APOS_26"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "cer2_26_c": 1.0, "h_c": -1.0, "cer1_26_c": -1.0}, "id": "CERH126_copy1", "gene_reaction_rule": "YDR297W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Ceramide 1 synthase 24C ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CERS124"]}, "metabolites": {"ttccoa_c": -1.0, "cer1_24_c": 1.0, "coa_c": 1.0, "h_c": 1.0, "sphgn_c": -1.0}, "id": "CERS124", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid Metabolism", "name": "Ceramide 1 synthase 26C ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CERS126"]}, "metabolites": {"cer1_26_c": 1.0, "hexccoa_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "sphgn_c": -1.0}, "id": "CERS126", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid Metabolism", "name": "Ceramide 2 synthase 24C ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CERS224"]}, "metabolites": {"ttccoa_c": -1.0, "psphings_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "cer2_24_c": 1.0}, "id": "CERS224", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid Metabolism", "name": "Ceramide 2 synthase 26C ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CERS226"]}, "metabolites": {"psphings_c": -1.0, "cer2_26_c": 1.0, "hexccoa_c": -1.0, "coa_c": 1.0, "h_c": 1.0}, "id": "CERS226", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid Metabolism", "name": "Ceramide 1 hydroxylase 24C ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CERH124", "CERS2_APOS_24"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "cer1_24_c": -1.0, "nadph_c": -1.0, "cer2_24_c": 1.0, "nadp_c": 1.0, "h_c": -1.0}, "id": "CERH124_copy2", "gene_reaction_rule": "YMR272C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Ceramide 1 hydroxylase 26C ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CERH126", "CERS2_APOS_26"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "cer2_26_c": 1.0, "h_c": -1.0, "cer1_26_c": -1.0}, "id": "CERH126_copy2", "gene_reaction_rule": "YMR272C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Ceramide 3 synthase 24C ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CERS324"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "cer2_24_c": -1.0, "h_c": -1.0, "cer3_24_c": 1.0}, "id": "CERS324", "gene_reaction_rule": "YMR272C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Ceramide 3 synthase 26C ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CERS326"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "cer3_26_c": 1.0, "nadph_c": -1.0, "cer2_26_c": -1.0, "nadp_c": 1.0, "h_c": -1.0}, "id": "CERS326", "gene_reaction_rule": "YMR272C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Choline phosphate cytididyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHLPCTD"]}, "metabolites": {"ctp_c": -1.0, "cholp_c": -1.0, "ppi_c": 1.0, "cdpchol_c": 1.0, "h_c": -1.0}, "id": "CHLPCTD", "gene_reaction_rule": "YGR202C"}, {"subsystem": "Sterol Biosynthesis", "name": "Cholestenol delta isomerase lumped reaction", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHLSTI"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "ahcys_c": 1.0, "zymst_c": -1.0, "h_c": 1.0, "amet_c": -1.0, "ergtetrol_c": 1.0}, "id": "CHLSTI", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Choline transport via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHLt2"]}, "metabolites": {"chol_c": 1.0, "h_e": -1.0, "h_c": 1.0, "chol_e": -1.0}, "id": "CHLt2", "gene_reaction_rule": "YGL077C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Choline kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHOLK"]}, "metabolites": {"chol_c": -1.0, "cholp_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "CHOLK", "gene_reaction_rule": "YLR133W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Chorismate mutase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHORM"]}, "metabolites": {"chor_c": -1.0, "pphn_c": 1.0}, "id": "CHORM", "gene_reaction_rule": "YPR060C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Chorismate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHORS"]}, "metabolites": {"chor_c": 1.0, "pi_c": 1.0, "3psme_c": -1.0}, "id": "CHORS", "gene_reaction_rule": "YGL148W"}, {"subsystem": "Quinone Biosynthesis", "name": "Chorismate pyruvate lyase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHRPL"]}, "metabolites": {"4hbz_c": 1.0, "pyr_c": 1.0, "chor_c": -1.0}, "id": "CHRPL", "gene_reaction_rule": "YKL211C or YER090W"}, {"subsystem": "Aminosugar Metabolism", "name": "Chitin deacetylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHTNDA"]}, "metabolites": {"chitos_c": 1.0, "chitin_c": -1.0, "ac_c": 1.0, "h_c": 1.0, "h2o_c": -1.0}, "id": "CHTNDA", "gene_reaction_rule": "YLR308W or YLR307W"}, {"subsystem": "Glutamate metabolism", "name": "Chitin synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHTNS"]}, "metabolites": {"chitin_c": 1.0, "udp_c": 1.0, "h_c": 1.0, "udpacgal_c": -1.0}, "id": "CHTNS", "gene_reaction_rule": "YNL192W or YBR023C or YBR038W"}, {"subsystem": "Transport, Extracellular", "name": "Citrate reversible transport via symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CITt2r"]}, "metabolites": {"cit_e": -1.0, "h_e": -1.0, "h_c": 1.0, "cit_c": 1.0}, "id": "CITt2r", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Citrate transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CITtam"]}, "metabolites": {"cit_m": 1.0, "mal__L_c": 1.0, "mal__L_m": -1.0, "cit_c": -1.0}, "id": "CITtam", "gene_reaction_rule": "YBR291C"}, {"subsystem": "Transport, Peroxisomal", "name": "Citratemalate antiport into peroxisome", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CITtap"]}, "metabolites": {"mal__L_x": 1.0, "mal__L_c": -1.0, "cit_x": -1.0, "cit_c": 1.0}, "id": "CITtap", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Citrate transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CITtbm"]}, "metabolites": {"pep_c": 1.0, "cit_m": 1.0, "pep_m": -1.0, "cit_c": -1.0}, "id": "CITtbm", "gene_reaction_rule": "YBR291C"}, {"subsystem": "Transport, Mitochondrial", "name": "Citrate transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CITtcm"]}, "metabolites": {"cit_m": 1.0, "icit_c": 1.0, "icit_m": -1.0, "cit_c": -1.0}, "id": "CITtcm", "gene_reaction_rule": "YBR291C"}, {"subsystem": "Transport, Peroxisomal", "name": "Citrateisocitrate antiport into peroxisome", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CITtcp"]}, "metabolites": {"icit_x": -1.0, "icit_c": 1.0, "cit_x": 1.0, "cit_c": -1.0}, "id": "CITtcp", "gene_reaction_rule": ""}, {"subsystem": "Phospholipid Biosynthesis", "name": "Cardiolipin synthase yeast specific mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CLPNSm_SC"]}, "metabolites": {"cmp_m": 1.0, "h_m": 1.0, "pg_SC_m": -0.01, "cdpdag_SC_m": -0.01, "clpn_SC_m": 0.01}, "id": "CLPNSm_SC", "gene_reaction_rule": "YDL142C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "CMP nucleosidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CMPN"]}, "metabolites": {"h2o_c": -1.0, "csn_c": 1.0, "r5p_c": 1.0, "cmp_c": -1.0}, "id": "CMPN", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "CMPtm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CMPtm"]}, "metabolites": {"cmp_m": 1.0, "cmp_c": -1.0}, "id": "CMPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "CO2 transporter via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CO2t"]}, "metabolites": {"co2_c": 1.0, "co2_e": -1.0}, "id": "CO2t", "gene_reaction_rule": ""}, {"subsystem": "Transport, Golgi Apparatus", "name": "CO2 Golgi transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CO2tg"]}, "metabolites": {"co2_c": -1.0, "co2_g": 1.0}, "id": "CO2tg", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "CO2 transport diffusion mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CO2tm"]}, "metabolites": {"co2_c": -1.0, "co2_m": 1.0}, "id": "CO2tm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "CO2 nuclear transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CO2tn"]}, "metabolites": {"co2_c": 1.0, "co2_n": -1.0}, "id": "CO2tn", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "CO2 peroxisomal transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CO2tp"]}, "metabolites": {"co2_x": 1.0, "co2_c": -1.0}, "id": "CO2tp", "gene_reaction_rule": ""}, {"subsystem": "Transport, Vacuolar", "name": "CO2 vacuolar transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CO2tv"]}, "metabolites": {"co2_c": -1.0, "co2_v": 1.0}, "id": "CO2tv", "gene_reaction_rule": ""}, {"subsystem": "Porphyrin and Chlorophyll Metabolism", "name": "Coproporphyrinogen oxidase (O2 required)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CPPPGO"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "pppg9_c": 1.0, "cpppg3_c": -1.0, "h_c": -2.0, "co2_c": 2.0}, "id": "CPPPGO", "gene_reaction_rule": "YDR044W"}, {"subsystem": "Transport, Mitochondrial", "name": "Carnithine acetylcarnithine carrier mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CRNCARtm"]}, "metabolites": {"acrn_c": -1.0, "crn_c": 1.0, "acrn_m": 1.0, "crn_m": -1.0}, "id": "CRNCARtm", "gene_reaction_rule": "YOR100C"}, {"subsystem": "Transport, Peroxisomal", "name": "Carnitine acetylcarnitine carrier peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CRNCARtp"]}, "metabolites": {"acrn_c": 1.0, "crn_c": -1.0, "crn_x": 1.0, "acrn_x": -1.0}, "id": "CRNCARtp", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L carnitine reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CRNt"]}, "metabolites": {"crn_c": 1.0, "crn_e": -1.0}, "id": "CRNt", "gene_reaction_rule": "YBR132C"}, {"subsystem": "Transport, Mitochondrial", "name": "L carnitine transport out of mitochondria via diffusion", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CRNtim"]}, "metabolites": {"crn_c": 1.0, "crn_m": -1.0}, "id": "CRNtim", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Carnitine transport into peroxsiome", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CRNtp"]}, "metabolites": {"crn_c": -1.0, "crn_x": 1.0}, "id": "CRNtp", "gene_reaction_rule": ""}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Carnitine O acetyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CSNAT"]}, "metabolites": {"acrn_c": 1.0, "crn_c": -1.0, "coa_c": 1.0, "accoa_c": -1.0}, "id": "CSNATr", "gene_reaction_rule": ""}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Carnitine O aceyltransferase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CSNATifm"]}, "metabolites": {"accoa_m": 1.0, "coa_m": -1.0, "crn_m": 1.0, "acrn_m": -1.0}, "id": "CSNATm", "gene_reaction_rule": "YAR035W"}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "CSNATirm", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CSNATirm"]}, "metabolites": {"accoa_m": -1.0, "coa_m": 1.0, "acrn_m": 1.0, "crn_m": -1.0}, "id": "CSNATirm", "gene_reaction_rule": "YML042W"}, {"subsystem": "Glutamate metabolism", "name": "Carnitine O acetyltransferase reverse direction peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CSNATirp"]}, "metabolites": {"acrn_x": 1.0, "accoa_x": -1.0, "crn_x": -1.0, "coa_x": 1.0}, "id": "CSNATp", "gene_reaction_rule": "YML042W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Cytosine deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CSND"]}, "metabolites": {"ura_c": 1.0, "h2o_c": -1.0, "csn_c": -1.0, "h_c": -1.0, "nh4_c": 1.0}, "id": "CSND", "gene_reaction_rule": "YPR062W"}, {"subsystem": "Transport, Extracellular", "name": "Cytosine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CSNt2"]}, "metabolites": {"csn_c": 1.0, "h_e": -1.0, "h_c": 1.0, "csn_e": -1.0}, "id": "CSNt2", "gene_reaction_rule": "YGL186C or YER060W_A or YER060W or YER056C"}, {"subsystem": "Citric Acid Cycle", "name": "Citrate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CSm"]}, "metabolites": {"cit_m": 1.0, "h2o_m": -1.0, "oaa_m": -1.0, "accoa_m": -1.0, "coa_m": 1.0, "h_m": 1.0}, "id": "CSm", "gene_reaction_rule": "YNR001C or YPR001W"}, {"subsystem": "Citric Acid Cycle", "name": "Citrate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CSp"]}, "metabolites": {"oaa_x": -1.0, "h_x": 1.0, "accoa_x": -1.0, "cit_x": 1.0, "h2o_x": -1.0, "coa_x": 1.0}, "id": "CSp", "gene_reaction_rule": "YCR005C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "CTP synthase NH3 ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CTPS1"]}, "metabolites": {"utp_c": -1.0, "atp_c": -1.0, "h_c": 2.0, "adp_c": 1.0, "ctp_c": 1.0, "pi_c": 1.0, "nh4_c": -1.0}, "id": "CTPS1", "gene_reaction_rule": "YBL039C or YJR103W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "CTP synthase (glutamine)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CTPS2"]}, "metabolites": {"utp_c": -1.0, "atp_c": -1.0, "glu__L_c": 1.0, "h2o_c": -1.0, "h_c": 2.0, "adp_c": 1.0, "ctp_c": 1.0, "pi_c": 1.0, "gln__L_c": -1.0}, "id": "CTPS2", "gene_reaction_rule": "YBL039C or YJR103W"}, {"subsystem": "Oxidative Phosphorylation", "name": "Cytochrome c oxidase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYOOm"]}, "metabolites": {"h2o_m": 2.0, "o2_m": -1.0, "ficytc_m": 4.0, "h_c": 6.0, "h_m": -6.0, "focytc_m": -4.0}, "id": "CYOOm", "gene_reaction_rule": "(YGL191W and YDL067C and Q0275 and YLR038C and YGL187C and Q0250 and Q0045 and YMR256C and YNL052W and YHR051W and YLR395C) or (YGL191W and YDL067C and Q0275 and YLR038C and YGL187C and Q0250 and Q0045 and YMR256C and YHR051W and YIL111W and YLR395C)"}, {"subsystem": "Oxidative Phosphorylation", "name": "Ubiquinol 6 cytochrome c reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYOR_u6m"]}, "metabolites": {"ficytc_m": -2.0, "q6h2_m": -1.0, "q6_m": 1.0, "h_m": -1.5, "focytc_m": 2.0, "h_c": 1.5}, "id": "CYOR_u6m", "gene_reaction_rule": "YHR001W_A and YJL166W and YGR183C and YBL045C and YFR033C and YEL024W and Q0105 and YDR529C and YOR065W and YPR191W"}, {"subsystem": "Cysteine Metabolism", "name": "Cysteine synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYSS"]}, "metabolites": {"cys__L_c": 1.0, "ac_c": 1.0, "acser_c": -1.0, "h_c": 1.0, "h2s_c": -1.0}, "id": "CYSS", "gene_reaction_rule": "YGR012W"}, {"subsystem": "Methionine Metabolism", "name": "Cystathionine g lyase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYSTGL"]}, "metabolites": {"cys__L_c": 1.0, "h2o_c": -1.0, "2obut_c": 1.0, "nh4_c": 1.0, "cyst__L_c": -1.0}, "id": "CYSTGL", "gene_reaction_rule": "YAL012W"}, {"subsystem": "Methionine Metabolism", "name": "Cystathionine b-lyase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYSTL"]}, "metabolites": {"hcys__L_c": 1.0, "pyr_c": 1.0, "h2o_c": -1.0, "cyst__L_c": -1.0, "nh4_c": 1.0}, "id": "CYSTL", "gene_reaction_rule": "YFR055W"}, {"subsystem": "Methionine Metabolism", "name": "Cystathione b lyase peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYSTLp"]}, "metabolites": {"h2o_x": -1.0, "hcys__L_x": 1.0, "cyst__L_x": -1.0, "nh4_x": 1.0, "pyr_x": 1.0}, "id": "CYSTLp", "gene_reaction_rule": "YGL184C"}, {"subsystem": "Cysteine Metabolism", "name": "Cysteinyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYSTRS"]}, "metabolites": {"cys__L_c": -1.0, "atp_c": -1.0, "cystrna_c": 1.0, "ppi_c": 1.0, "amp_c": 1.0, "trnacys_c": -1.0}, "id": "CYSTRS", "gene_reaction_rule": "YNL247W"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Cystathionine beta synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYSTS"]}, "metabolites": {"hcys__L_c": -1.0, "h2o_c": 1.0, "ser__L_c": -1.0, "cyst__L_c": 1.0}, "id": "CYSTS", "gene_reaction_rule": "YGR155W"}, {"subsystem": "Transport, Peroxisomal", "name": "Cystathione peroxisomal transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CYSTtp"]}, "metabolites": {"cyst__L_x": 1.0, "cyst__L_c": -1.0}, "id": "CYSTtp", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L cysteine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CYSt2r"]}, "metabolites": {"cys__L_c": 1.0, "h_e": -1.0, "h_c": 1.0, "cys__L_e": -1.0}, "id": "CYSt2r", "gene_reaction_rule": "YOL020W or YDR046C or YKR039W or YBR068C or YDR508C or YBR069C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Cytidine deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYTD"]}, "metabolites": {"cytd_c": -1.0, "uri_c": 1.0, "h2o_c": -1.0, "h_c": -1.0, "nh4_c": 1.0}, "id": "CYTD", "gene_reaction_rule": "YLR245C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Cytidine kinase (GTP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYTDK2"]}, "metabolites": {"cytd_c": -1.0, "gdp_c": 1.0, "gtp_c": -1.0, "h_c": 1.0, "cmp_c": 1.0}, "id": "CYTDK2", "gene_reaction_rule": "YNR012W"}, {"subsystem": "Transport, Extracellular", "name": "Cytidine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CYTDt2"]}, "metabolites": {"cytd_c": 1.0, "h_e": -1.0, "h_c": 1.0, "cytd_e": -1.0}, "id": "CYTDt2", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Cytidylate kinase (CMP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CYTK1"]}, "metabolites": {"cdp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "cmp_c": -1.0}, "id": "CYTK1", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Cytidylate kinase (dCMP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["CYTK2"]}, "metabolites": {"dcmp_c": -1.0, "atp_c": -1.0, "adp_c": 1.0, "dcdp_c": 1.0}, "id": "CYTK2", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Deoxyadenosine deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DADA"]}, "metabolites": {"dad_2_c": -1.0, "din_c": 1.0, "h_c": -1.0, "h2o_c": -1.0, "nh4_c": 1.0}, "id": "DADA", "gene_reaction_rule": "YNL141W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Deoxyadenylate kinase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DADK"]}, "metabolites": {"dadp_c": 1.0, "damp_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "DADK", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Deoxyadenosine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DADNt2"]}, "metabolites": {"dad_2_c": 1.0, "h_e": -1.0, "h_c": 1.0, "dad_2_e": -1.0}, "id": "DADNt2", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "DADP nuclear transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DADPtn"]}, "metabolites": {"dadp_c": -1.0, "dadp_n": 1.0}, "id": "DADPtn", "gene_reaction_rule": ""}, {"subsystem": "Phospholipid Biosynthesis", "name": "Diacylglycerol cholinephosphotransferase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DAGCPT_SC"]}, "metabolites": {"h_c": 1.0, "12dgr_SC_c": -0.01, "pc_SC_c": 0.01, "cdpchol_c": -1.0, "cmp_c": 1.0}, "id": "DAGCPT_SC", "gene_reaction_rule": "YNL130C or YHR123W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Diacylglycerol pyrophosphate phosphatase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DAGPYP_SC"]}, "metabolites": {"12dgr_SC_c": 0.01, "h2o_c": -1.0, "pa_SC_c": -0.01, "pi_c": 1.0}, "id": "DAGPYP_SC", "gene_reaction_rule": "YDR503C or YDR284C"}, {"subsystem": "Transport, Extracellular", "name": "7 8 Diaminononanoate reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DANNt2"]}, "metabolites": {"dann_e": -1.0, "h_e": -1.0, "h_c": 1.0, "dann_c": 1.0}, "id": "DANNt2", "gene_reaction_rule": ""}, {"subsystem": "Phospholipid Biosynthesis", "name": "CDP Diacylglycerol synthetase yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DASYN_SC"]}, "metabolites": {"ctp_c": -1.0, "ppi_c": 1.0, "pa_SC_c": -0.01, "h_c": -1.0, "cdpdag_SC_c": 0.01}, "id": "DASYN_SC", "gene_reaction_rule": "YBR029C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "CDP Diacylglycerol synthetase yeast specific mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DASYNm_SC"]}, "metabolites": {"cdpdag_SC_m": 0.01, "h_m": -1.0, "ppi_m": 1.0, "pa_SC_m": -0.01, "ctp_m": -1.0}, "id": "DASYNm_SC", "gene_reaction_rule": "YBR029C"}, {"subsystem": "Riboflavin Metabolism", "name": "3,4-Dihydroxy-2-butanone-4-phosphate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DB4PS"]}, "metabolites": {"for_c": 1.0, "ru5p__D_c": -1.0, "db4p_c": 1.0, "h_c": 1.0}, "id": "DB4PS", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Dethiobiotin synthase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DBTSr"]}, "metabolites": {"co2_c": -1.0, "atp_c": -1.0, "dtbt_c": 1.0, "h_c": 3.0, "adp_c": 1.0, "pi_c": 1.0, "dann_c": -1.0}, "id": "DBTS", "gene_reaction_rule": "YNR057C"}, {"subsystem": "Transport, Nuclear", "name": "DCDP nuclear transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DCDPtn"]}, "metabolites": {"dcdp_n": 1.0, "dcdp_c": -1.0}, "id": "DCDPtn", "gene_reaction_rule": ""}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "DCMP deaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DCMPDA"]}, "metabolites": {"dcmp_c": -1.0, "h2o_c": -1.0, "h_c": -1.0, "dump_c": 1.0, "nh4_c": 1.0}, "id": "DCMPDA", "gene_reaction_rule": "YHR144C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "DCTP deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DCTPD"]}, "metabolites": {"dctp_c": -1.0, "h2o_c": -1.0, "nh4_c": 1.0, "h_c": -1.0, "dutp_c": 1.0}, "id": "DCTPD", "gene_reaction_rule": "YHR144C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Deoxycytidine deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DCYTD"]}, "metabolites": {"dcyt_c": -1.0, "h2o_c": -1.0, "h_c": -1.0, "duri_c": 1.0, "nh4_c": 1.0}, "id": "DCYTD", "gene_reaction_rule": "YLR245C"}, {"subsystem": "Transport, Extracellular", "name": "Deoxycytidine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DCYTt2"]}, "metabolites": {"dcyt_c": 1.0, "h_e": -1.0, "h_c": 1.0, "dcyt_e": -1.0}, "id": "DCYTt2", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DDPA"]}, "metabolites": {"pep_c": -1.0, "e4p_c": -1.0, "pi_c": 1.0, "2dda7p_c": 1.0, "h2o_c": -1.0}, "id": "DDPA", "gene_reaction_rule": "YBR249C or YDR035W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "2 deoxy D arabino heptulosonate 7 phosphate synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DDPAm"]}, "metabolites": {"e4p_m": -1.0, "2dda7p_m": 1.0, "h2o_m": -1.0, "pi_m": 1.0, "pep_m": -1.0}, "id": "DDPAm", "gene_reaction_rule": "YDR035W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Myristicoyl CoA desaturase n C140CoA n C141CoA ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DESAT14"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "nadp_c": 1.0, "nadph_c": -1.0, "tdecoa_c": 1.0, "tdcoa_c": -1.0, "h_c": -1.0}, "id": "DESAT14", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Palmitoyl CoA desaturase n C160CoA n C161CoA ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DESAT16"]}, "metabolites": {"o2_c": -1.0, "hdcoa_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h2o_c": 2.0, "pmtcoa_c": -1.0, "h_c": -1.0}, "id": "DESAT16", "gene_reaction_rule": "YGL055W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Stearoyl CoA desaturase n C180CoA n C181CoA ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DESAT18"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "odecoa_c": 1.0, "nadph_c": -1.0, "stcoa_c": -1.0, "nadp_c": 1.0, "h_c": -1.0}, "id": "DESAT18", "gene_reaction_rule": "YGL055W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Oleoyl CoA desaturase n C181CoA n C182CoA ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DESAT18_2"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "odecoa_c": -1.0, "nadph_c": -1.0, "nadp_c": 1.0, "h_c": -1.0, "ocdycacoa_c": 1.0}, "id": "DESAT18_2", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "DGDP nuclear transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DGDPtn"]}, "metabolites": {"dgdp_c": -1.0, "dgdp_n": 1.0}, "id": "DGDPtn", "gene_reaction_rule": ""}, {"subsystem": "Galactose metabolism", "name": "Alpha D glucoside glucohydrase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DGGH"]}, "metabolites": {"glc__D_c": 1.0, "h2o_c": -1.0, "gal_c": 1.0, "6dg_c": -1.0}, "id": "DGGH", "gene_reaction_rule": "YJL221C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Deoxyguanylate kinase (dGMP:ATP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DGK1"]}, "metabolites": {"dgdp_c": 1.0, "dgmp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "DGK1", "gene_reaction_rule": "YDR454C"}, {"subsystem": "Transport, Extracellular", "name": "Deoxyguanosine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DGSNt2"]}, "metabolites": {"dgsn_c": 1.0, "h_e": -1.0, "h_c": 1.0, "dgsn_e": -1.0}, "id": "DGSNt2", "gene_reaction_rule": ""}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Dihydroxy acid dehydratase 2 3 dihydroxy 3 methylbutanoate mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHAD1m"]}, "metabolites": {"23dhmb_m": -1.0, "3mob_m": 1.0, "h2o_m": 1.0}, "id": "DHAD1m", "gene_reaction_rule": "YJR016C"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Dihydroxy acid dehydratase 2 3 dihydroxy 3 methylpentanoate mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHAD2m"]}, "metabolites": {"h2o_m": 1.0, "23dhmp_m": -1.0, "3mop_m": 1.0}, "id": "DHAD2m", "gene_reaction_rule": "YJR016C"}, {"subsystem": "Glycerolipid Metabolism", "name": "Dihydroxyacetone kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHAK"]}, "metabolites": {"dhap_c": 1.0, "dha_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "DHAK", "gene_reaction_rule": "YML070W or YFL053W"}, {"subsystem": "Transport, Mitochondrial", "name": "Dihydroxyacetone phosphate transport mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHAPtm"]}, "metabolites": {"dhap_c": 1.0, "dhap_m": -1.0}, "id": "DHAPtm", "gene_reaction_rule": ""}, {"subsystem": "Folate Metabolism", "name": "Dihydrofolate reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHFRi"]}, "metabolites": {"h_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "thf_c": 1.0, "dhf_c": -1.0}, "id": "DHFR", "gene_reaction_rule": "YOR236W"}, {"subsystem": "Folate Metabolism", "name": "Dihydrofolate reductase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHFRim"]}, "metabolites": {"thf_m": 1.0, "nadph_m": -1.0, "h_m": -1.0, "nadp_m": 1.0, "dhf_m": -1.0}, "id": "DHFRim", "gene_reaction_rule": "YOR236W"}, {"subsystem": "Folate Metabolism", "name": "DHFS", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHFS"]}, "metabolites": {"dhf_c": 1.0, "atp_c": -1.0, "glu__L_c": -1.0, "adp_c": 1.0, "dhpt_c": -1.0, "pi_c": 1.0}, "id": "DHFS_1", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Dihydrofolate reversible mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DHFtm"]}, "metabolites": {"dhf_m": 1.0, "dhf_c": -1.0}, "id": "DHFtm", "gene_reaction_rule": ""}, {"subsystem": "Folate Metabolism", "name": "Dihydroneopterin aldolase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHNPAm"]}, "metabolites": {"2ahhmp_m": 1.0, "gcald_m": 1.0, "h_m": 1.0, "dhnpt_m": -1.0}, "id": "DHNPAm", "gene_reaction_rule": "YNL256W"}, {"subsystem": "Transport, Mitochondrial", "name": "Dhnpt mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DHNPTtm"]}, "metabolites": {"dhnpt_c": -1.0, "dhnpt_m": 1.0}, "id": "DHNPTtm", "gene_reaction_rule": ""}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Dihydoorotic acid dehydrogenase irreversible ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DHORD"]}, "metabolites": {"o2_c": -1.0, "dhor__S_c": -1.0, "orot_c": 1.0, "h2o2_c": 1.0}, "id": "DHORDi", "gene_reaction_rule": "YKL216W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Dihydoorotic acid ubiquinone 6 irreversible", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DHORD4"]}, "metabolites": {"q6_m": -1.0, "dhor__S_c": -1.0, "q6h2_m": 1.0, "orot_c": 1.0}, "id": "DHORD4i", "gene_reaction_rule": "YKL216W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Dihydroorotase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DHORTS"]}, "metabolites": {"cbasp_c": 1.0, "h2o_c": -1.0, "dhor__S_c": -1.0, "h_c": 1.0}, "id": "DHORTS", "gene_reaction_rule": "YLR420W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "DHORTSn", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DHORTSn"]}, "metabolites": {"h_n": 1.0, "cbasp_n": 1.0, "dhor__S_n": -1.0, "h2o_n": -1.0}, "id": "DHORTSn", "gene_reaction_rule": "YJL130C"}, {"subsystem": "Transport, Nuclear", "name": "DHORtn", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DHORtn"]}, "metabolites": {"dhor__S_c": -1.0, "dhor__S_n": 1.0}, "id": "DHORtn", "gene_reaction_rule": ""}, {"subsystem": "Riboflavin Metabolism", "name": "Diaminohydroxyphosphoribosylaminopyrimidine deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHPPDA"]}, "metabolites": {"5apru_c": 1.0, "h2o_c": -1.0, "h_c": -1.0, "25dhpp_c": -1.0, "nh4_c": 1.0}, "id": "DHPPDA", "gene_reaction_rule": "YBR153W"}, {"subsystem": "Folate Metabolism", "name": "Dihydropteroate synthase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHPSm"]}, "metabolites": {"2ahhmp_m": -1.0, "4abz_m": -1.0, "h2o_m": 1.0, "dhpt_m": 1.0}, "id": "DHPSm", "gene_reaction_rule": "YNL256W"}, {"subsystem": "Transport, Mitochondrial", "name": "Dihydropteroate mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DHPTtm"]}, "metabolites": {"dhpt_c": -1.0, "dhpt_m": 1.0}, "id": "DHPTtm", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "3-dehydroquinate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHQS"]}, "metabolites": {"2dda7p_c": -1.0, "pi_c": 1.0, "3dhq_c": 1.0}, "id": "DHQS", "gene_reaction_rule": "YDR127W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "3-dehydroquinate dehydratase, irreversible", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DHQTi"]}, "metabolites": {"3dhsk_c": 1.0, "h2o_c": 1.0, "3dhq_c": -1.0}, "id": "DHQTi", "gene_reaction_rule": "YDR127W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Diamine transaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DIAT"]}, "metabolites": {"sprm_c": -1.0, "N1sprm_c": 1.0, "coa_c": 1.0, "h_c": 1.0, "accoa_c": -1.0}, "id": "DIAT", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "DICtm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DICtm"]}, "metabolites": {"mal__L_m": 1.0, "mal__L_c": -1.0, "succ_m": -1.0, "succ_c": 1.0}, "id": "DICtm", "gene_reaction_rule": "YLR348C"}, {"subsystem": "Transport, Extracellular", "name": "Deoxyinosine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DINSt2"]}, "metabolites": {"din_c": 1.0, "h_e": -1.0, "din_e": -1.0, "h_c": 1.0}, "id": "DINSt2", "gene_reaction_rule": ""}, {"name": "2-Oxoglutarate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_akg_LPAREN_e_RPAREN_"]}, "metabolites": {"akg_e": -1.0}, "id": "EX_akg_e", "gene_reaction_rule": ""}, {"subsystem": "Methionine Metabolism", "name": "Diphthine synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DIPS"]}, "metabolites": {"cmaphis_c": 1.0, "ahcys_c": 1.0, "h_c": 1.0, "caphis_c": -1.0, "amet_c": -1.0}, "id": "DIPS", "gene_reaction_rule": "YLR172C"}, {"subsystem": "Sterol Biosynthesis", "name": "Dimethylallyltranstransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DMATT"]}, "metabolites": {"dmpp_c": -1.0, "ppi_c": 1.0, "ipdp_c": -1.0, "grdp_c": 1.0}, "id": "DMATT", "gene_reaction_rule": "YJL167W"}, {"subsystem": "Quinone Biosynthesis", "name": "DMQMT6m", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DMQMT6m"]}, "metabolites": {"ahcys_m": 1.0, "h_m": 1.0, "q6h2_m": 1.0, "2omhmbl_5_m": -1.0, "amet_m": -1.0}, "id": "DMQMT6m", "gene_reaction_rule": "YOL096C"}, {"subsystem": "Folate Metabolism", "name": "Dihydroneopterin monophosphate dephosphorylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DNMPPA"]}, "metabolites": {"h2o_c": -1.0, "dhnpt_c": 1.0, "pi_c": 1.0, "dhpmp_c": -1.0}, "id": "DNMPPA", "gene_reaction_rule": "YDL100C"}, {"subsystem": "Folate Metabolism", "name": "Dihydroneopterin triphosphate pyrophosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DNTPPA"]}, "metabolites": {"h_c": 1.0, "h2o_c": -1.0, "ppi_c": 1.0, "dhpmp_c": 1.0, "ahdt_c": -1.0}, "id": "DNTPPA", "gene_reaction_rule": ""}, {"subsystem": "Glycoprotein Metabolism", "name": "Dolichol kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DOLK"]}, "metabolites": {"cdp_c": 1.0, "ctp_c": -1.0, "dolp_c": 1.0, "h_c": 1.0, "dolichol_c": -1.0}, "id": "DOLK", "gene_reaction_rule": "YMR013C"}, {"subsystem": "Glycoprotein Metabolism", "name": "Dolichyl phosphate mannose protein mannosyltransferase endoplasmic reticular", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DOLPMMer"]}, "metabolites": {"mannan_r": 1.0, "dolp_r": 1.0, "h_r": 1.0, "dolmanp_r": -1.0}, "id": "DOLPMMer", "gene_reaction_rule": "YDL093W or (YAL023C and YDL095W) or YJR143C or YOR321W or YGR199W"}, {"subsystem": "Glycoprotein Metabolism", "name": "Dolichyl phosphate D mannosyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DOLPMTcer"]}, "metabolites": {"gdpmann_c": -1.0, "dolp_c": -1.0, "gdp_c": 1.0, "dolmanp_r": 1.0}, "id": "DOLPMTcer", "gene_reaction_rule": "YPR183W"}, {"subsystem": "Transport, Endoplasmic Reticular", "name": "Dolichol phosphate endoplasmic reticular transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DOLPt2er"]}, "metabolites": {"dolp_r": 1.0, "dolp_c": -1.0, "h_r": 1.0, "h_c": -1.0}, "id": "DOLPt2er", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Dephospho-CoA kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DPCOAK"]}, "metabolites": {"dpcoa_c": -1.0, "coa_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "DPCOAK", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Dephospho CoA kinase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DPCOAKm"]}, "metabolites": {"adp_m": 1.0, "atp_m": -1.0, "coa_m": 1.0, "h_m": 1.0, "dpcoa_m": -1.0}, "id": "DPCOAKm", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Diphosphoglyceromutase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DPGM"]}, "metabolites": {"23dpg_c": 1.0, "13dpg_c": -1.0, "h_c": 1.0}, "id": "DPGM", "gene_reaction_rule": "YKL152C"}, {"subsystem": "Sterol Biosynthesis", "name": "Diphosphomevalonate decarboxylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DPMVD"]}, "metabolites": {"5dpmev_c": -1.0, "ipdp_c": 1.0, "co2_c": 1.0, "atp_c": -1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "DPMVD", "gene_reaction_rule": "YNR043W"}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "2-dehydropantoate 2-reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DPR"]}, "metabolites": {"pant__R_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "2dhp_c": -1.0}, "id": "DPR", "gene_reaction_rule": "YHR063C"}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "2 dehydropantoate 2 reductase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DPRm"]}, "metabolites": {"2dhp_m": -1.0, "nadph_m": -1.0, "h_m": -1.0, "pant__R_m": 1.0, "nadp_m": 1.0}, "id": "DPRm", "gene_reaction_rule": "YLR355C"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Deoxyribokinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DRBK"]}, "metabolites": {"adp_c": 1.0, "2dr5p_c": 1.0, "h_c": 1.0, "atp_c": -1.0, "drib_c": -1.0}, "id": "DRBK", "gene_reaction_rule": "YCR036W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "DTMP kinase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DTMPK"]}, "metabolites": {"dtmp_c": -1.0, "dtdp_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "DTMPK", "gene_reaction_rule": "YJR057W"}, {"subsystem": "Transport, Extracellular", "name": "DTTP reversible uniport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DTTPt"]}, "metabolites": {"dttp_e": -1.0, "dttp_c": 1.0}, "id": "DTTPt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "DUMP nuclear transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DUMPtn"]}, "metabolites": {"dump_n": 1.0, "dump_c": -1.0}, "id": "DUMPtn", "gene_reaction_rule": ""}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Deoxyuridine kinase (ATP:Deoxyuridine)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DURIK1"]}, "metabolites": {"dump_c": 1.0, "duri_c": -1.0, "h_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "DURIK1", "gene_reaction_rule": ""}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Deoxyuridine phosphorylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["DURIPP"]}, "metabolites": {"ura_c": 1.0, "2dr1p_c": 1.0, "pi_c": -1.0, "duri_c": -1.0}, "id": "DURIPP", "gene_reaction_rule": "YLR209C"}, {"subsystem": "Transport, Extracellular", "name": "Deoxyuridine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DURIt2"]}, "metabolites": {"duri_e": -1.0, "h_e": -1.0, "h_c": 1.0, "duri_c": 1.0}, "id": "DURIt2", "gene_reaction_rule": ""}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "DUTP diphosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DUTPDP"]}, "metabolites": {"h2o_c": -1.0, "ppi_c": 1.0, "dutp_c": -1.0, "dump_c": 1.0, "h_c": 1.0}, "id": "DUTPDP", "gene_reaction_rule": "YBR252W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Deoxyhypusine synthase cytosolicmitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DXHPScm"]}, "metabolites": {"h2o_c": -1.0, "4abutn_c": 1.0, "spmd_c": -1.0, "q6h2_m": 1.0, "q6_m": -1.0, "13dampp_c": 1.0}, "id": "DXHPScm", "gene_reaction_rule": "YHR068W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "D lactate dehydrogenase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["D_LACDm"]}, "metabolites": {"ficytc_m": -2.0, "lac__D_m": -1.0, "pyr_m": 1.0, "focytc_m": 2.0}, "id": "D_LACDm", "gene_reaction_rule": "YDL174C"}, {"subsystem": "Transport, Mitochondrial", "name": "D lactate transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["D_LACtm"]}, "metabolites": {"lac__D_m": 1.0, "h_m": 1.0, "lac__D_c": -1.0, "h_c": -1.0}, "id": "D_LACtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "L erythro 4 hydroxyglutamate mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["E4HGLUtm"]}, "metabolites": {"e4hglu_c": -1.0, "e4hglu_m": 1.0}, "id": "E4HGLUtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "L erythro 4 hydroxyglutamate peroxisomal transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["E4HGLUtp"]}, "metabolites": {"e4hglu_x": 1.0, "e4hglu_c": -1.0}, "id": "E4HGLUtp", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "D erythrose 4 phosphate mtiochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["E4Ptm"]}, "metabolites": {"e4p_c": -1.0, "e4p_m": 1.0}, "id": "E4Ptm", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydratase 3 hydroxyhexacosyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ECOAH11p"]}, "metabolites": {"h2o_x": -1.0, "hxc2coa_x": -1.0, "3hxccoa_x": 1.0}, "id": "ECOAH11p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydratase 3 hydroxydecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ECOAH4p"]}, "metabolites": {"h2o_x": 1.0, "3hdcoa_x": -1.0, "dc2coa_x": 1.0}, "id": "ECOAH4p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydratase 3 hydroxydodecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ECOAH5p"]}, "metabolites": {"3hddcoa_x": -1.0, "h2o_x": 1.0, "dd2coa_x": 1.0}, "id": "ECOAH5p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydratase 3 hydroxytetradecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ECOAH6p"]}, "metabolites": {"3htdcoa_x": -1.0, "h2o_x": 1.0, "td2coa_x": 1.0}, "id": "ECOAH6p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydratase 3 hydroxyhexadecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ECOAH7p"]}, "metabolites": {"h2o_x": 1.0, "3hhdcoa_x": -1.0, "hdd2coa_x": 1.0}, "id": "ECOAH7p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydratase 3 hydroxyoctadecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ECOAH8p"]}, "metabolites": {"h2o_x": 1.0, "3hodcoa_x": -1.0, "od2coa_x": 1.0}, "id": "ECOAH8p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "L erythro 4 Hydroxyglutamate2 oxoglutarate aminotransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EHGLAT"]}, "metabolites": {"akg_c": -1.0, "glu__L_c": 1.0, "e4hglu_c": -1.0, "4h2oglt_c": 1.0}, "id": "EHGLAT", "gene_reaction_rule": "YLR027C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "L erythro 4 Hydroxyglutamate2 oxoglutarate aminotransferase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EHGLATm"]}, "metabolites": {"4h2oglt_m": 1.0, "glu__L_m": 1.0, "e4hglu_m": -1.0, "akg_m": -1.0}, "id": "EHGLATm", "gene_reaction_rule": "YKL106W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "L erythro 4 Hydroxyglutamate2 oxoglutarate aminotransferase peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EHGLATp"]}, "metabolites": {"e4hglu_x": -1.0, "glu__L_x": 1.0, "akg_x": -1.0, "4h2oglt_x": 1.0}, "id": "EHGLATp", "gene_reaction_rule": "YLR027C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Enolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ENO"]}, "metabolites": {"pep_c": 1.0, "h2o_c": 1.0, "2pg_c": -1.0}, "id": "ENO", "gene_reaction_rule": "YOR393W or YPL281C or YHR174W or YGR254W or YMR323W"}, {"subsystem": "Galactose metabolism", "name": "Epimelibiose galactohydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["EPMGH"]}, "metabolites": {"h2o_c": -1.0, "epm_c": -1.0, "gal_c": 1.0, "man_c": 1.0}, "id": "EPMGH", "gene_reaction_rule": "YBR184W"}, {"subsystem": "Transport, Extracellular", "name": "Ergosterol reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ERGSTt"]}, "metabolites": {"ergst_e": -1.0, "ergst_c": 1.0}, "id": "ERGSTt", "gene_reaction_rule": "YOR011W"}, {"subsystem": "Transport, Endoplasmic Reticular", "name": "Ergosterol endoplasmic reticular transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ERGSTter"]}, "metabolites": {"ergst_c": 1.0, "ergst_r": -1.0}, "id": "ERGSTter", "gene_reaction_rule": ""}, {"subsystem": "Transport, Endoplasmic Reticular", "name": "Ergosta 5 6 22 24 28 tetraen 3beta ol endoplamic reticular transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ERGTETROLter"]}, "metabolites": {"ergtetrol_r": 1.0, "ergtetrol_c": -1.0}, "id": "ERGTETROLter", "gene_reaction_rule": ""}, {"subsystem": "Phospholipid Biosynthesis", "name": "Ethanolamine kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ETHAK"]}, "metabolites": {"h_c": 1.0, "ethamp_c": 1.0, "etha_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "ETHAK", "gene_reaction_rule": "YDR147W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Ethanolaminephosphotransferase yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ETHAPT_SC"]}, "metabolites": {"cdpea_c": -1.0, "12dgr_SC_c": -0.01, "pe_SC_c": 0.01, "h_c": 1.0, "cmp_c": 1.0}, "id": "ETHAPT_SC", "gene_reaction_rule": "YHR123W"}, {"subsystem": "Transport, Extracellular", "name": "Ethanol reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ETOHt"]}, "metabolites": {"etoh_e": -1.0, "etoh_c": 1.0}, "id": "ETOHt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Ethanol transport to mitochondria diffusion ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ETOHtm"]}, "metabolites": {"etoh_m": 1.0, "etoh_c": -1.0}, "id": "ETOHtm", "gene_reaction_rule": ""}, {"name": "1 3 beta D Glucan exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_13BDglcn_LPAREN_e_RPAREN_"]}, "metabolites": {"13BDglcn_e": -1.0}, "id": "EX_13BDglcn_e", "gene_reaction_rule": ""}, {"name": "4-Aminobutanoate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_4abut_LPAREN_e_RPAREN_"]}, "metabolites": {"4abut_e": -1.0}, "id": "EX_4abut_e", "gene_reaction_rule": ""}, {"name": "5 Amino 4 oxopentanoate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_5aop_LPAREN_e_RPAREN_"]}, "metabolites": {"5aop_e": -1.0}, "id": "EX_5aop_e", "gene_reaction_rule": ""}, {"name": "8 Amino 7 oxononanoate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_8aonn_LPAREN_e_RPAREN_"]}, "metabolites": {"8aonn_e": -1.0}, "id": "EX_8aonn_e", "gene_reaction_rule": ""}, {"name": "L Arabinitol exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_abt_LPAREN_e_RPAREN_"]}, "metabolites": {"abt_e": -1.0}, "id": "EX_abt_e", "gene_reaction_rule": ""}, {"name": "Acetate exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_ac_LPAREN_e_RPAREN_"]}, "metabolites": {"ac_e": -1.0}, "id": "EX_ac_e", "gene_reaction_rule": ""}, {"name": "Acetaldehyde exchange", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["EX_acald_LPAREN_e_RPAREN_"]}, "metabolites": {"acald_e": -1.0}, "id": "EX_acald_e", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acyl CoA peroxisomal transport via ABC system", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA182COAabcp"]}, "metabolites": {"pi_x": 1.0, "ocdycacoa_x": 1.0, "adp_x": 1.0, "h_x": 1.0, "ocdycacoa_c": -1.0, "h2o_x": -1.0, "atp_x": -1.0}, "id": "FA182COAabcp", "gene_reaction_rule": "YKL188C and YPL147W"}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA240tp"]}, "metabolites": {"ttc_c": -1.0, "ttc_x": 1.0}, "id": "FA240tp", "gene_reaction_rule": "YBR041W"}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA260tp"]}, "metabolites": {"hexc_x": 1.0, "hexc_c": -1.0}, "id": "FA260tp", "gene_reaction_rule": "YBR041W"}, {"subsystem": "Transport, Peroxisomal", "name": "Fatty acid peroxisomal transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FA80tp"]}, "metabolites": {"octa_x": 1.0, "octa_c": -1.0}, "id": "FA80tp", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase decanoate peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL100p"]}, "metabolites": {"dcacoa_x": 1.0, "dca_x": -1.0, "amp_x": 1.0, "coa_x": -1.0, "ppi_x": 1.0, "atp_x": -1.0}, "id": "FACOAL100p", "gene_reaction_rule": "YER015W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase dodecanoate peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL120p"]}, "metabolites": {"amp_x": 1.0, "coa_x": -1.0, "ppi_x": 1.0, "ddcacoa_x": 1.0, "atp_x": -1.0, "ddca_x": -1.0}, "id": "FACOAL120p", "gene_reaction_rule": "YER015W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase tetradecanoate ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL140"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "ttdca_c": -1.0, "tdcoa_c": 1.0}, "id": "FACOAL140", "gene_reaction_rule": "YOR317W or YMR246W or YIL009W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase tetradecanoate peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL140p"]}, "metabolites": {"tdcoa_x": 1.0, "ttdca_x": -1.0, "amp_x": 1.0, "coa_x": -1.0, "ppi_x": 1.0, "atp_x": -1.0}, "id": "FACOAL140p", "gene_reaction_rule": "YER015W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase tetradecenoate ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL141"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "tdecoa_c": 1.0, "ttdcea_c": -1.0}, "id": "FACOAL141", "gene_reaction_rule": "YOR317W or YMR246W or YIL009W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase tetradecenoate peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL141p"]}, "metabolites": {"ttdcea_x": -1.0, "tdecoa_x": 1.0, "amp_x": 1.0, "coa_x": -1.0, "ppi_x": 1.0, "atp_x": -1.0}, "id": "FACOAL141p", "gene_reaction_rule": "YER015W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase hexadecanoate ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL160"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "pmtcoa_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "hdca_c": -1.0}, "id": "FACOAL160", "gene_reaction_rule": "YOR317W or YMR246W or YIL009W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase hexadecanoate peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL160p"]}, "metabolites": {"hdca_x": -1.0, "pmtcoa_x": 1.0, "amp_x": 1.0, "coa_x": -1.0, "ppi_x": 1.0, "atp_x": -1.0}, "id": "FACOAL160p", "gene_reaction_rule": "YER015W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase hexadecenoate ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL161"]}, "metabolites": {"hdcoa_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "hdcea_c": -1.0, "coa_c": -1.0, "amp_c": 1.0}, "id": "FACOAL161", "gene_reaction_rule": "YOR317W or YMR246W or YIL009W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase hexadecenoate peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL161p"]}, "metabolites": {"hdcea_x": -1.0, "amp_x": 1.0, "coa_x": -1.0, "ppi_x": 1.0, "hdcoa_x": 1.0, "atp_x": -1.0}, "id": "FACOAL161p", "gene_reaction_rule": "YER015W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase octadecanoate ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL180"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "stcoa_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "ocdca_c": -1.0}, "id": "FACOAL180", "gene_reaction_rule": "YOR317W or YMR246W or YIL009W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase octadecenoate ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL181"]}, "metabolites": {"ocdcea_c": -1.0, "odecoa_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0}, "id": "FACOAL181", "gene_reaction_rule": "YOR317W or YMR246W or YIL009W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase octadecynoate ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL182"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "ocdycacoa_c": 1.0, "ocdcya_c": -1.0}, "id": "FACOAL182", "gene_reaction_rule": "YMR246W or YIL009W or YOR317W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase n C240 peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL240p"]}, "metabolites": {"amp_x": 1.0, "coa_x": -1.0, "ppi_x": 1.0, "ttccoa_x": 1.0, "ttc_x": -1.0, "atp_x": -1.0}, "id": "FACOAL240p", "gene_reaction_rule": "YBR041W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase n C260 peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL260p"]}, "metabolites": {"hexc_x": -1.0, "hexccoa_x": 1.0, "amp_x": 1.0, "coa_x": -1.0, "ppi_x": 1.0, "atp_x": -1.0}, "id": "FACOAL260p", "gene_reaction_rule": "YBR041W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid CoA ligase octanoate peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FACOAL80p"]}, "metabolites": {"occoa_x": 1.0, "amp_x": 1.0, "coa_x": -1.0, "ppi_x": 1.0, "octa_x": -1.0, "atp_x": -1.0}, "id": "FACOAL80p", "gene_reaction_rule": "YER015W"}, {"subsystem": "Transport, Mitochondrial", "name": "FADFMN antiport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FADFMNtm"]}, "metabolites": {"fad_m": 1.0, "fmn_m": -1.0, "fmn_c": 1.0, "fad_c": -1.0}, "id": "FADFMNtm", "gene_reaction_rule": "YIL134W"}, {"subsystem": "Pyruvate Metabolism", "name": "Formaldehyde dehydrogenase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FALDH"]}, "metabolites": {"Sfglutth_c": 1.0, "fald_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0, "gthrd_c": -1.0}, "id": "FALDH", "gene_reaction_rule": "YDL168W"}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO141p_even"]}, "metabolites": {"nadh_x": 6.0, "tdecoa_x": -1.0, "h2o2_x": 6.0, "accoa_x": 7.0, "h_x": 5.0, "nad_x": -6.0, "nadp_x": 1.0, "h2o_x": -6.0, "o2_x": -6.0, "coa_x": -6.0, "nadph_x": -1.0}, "id": "FAO141p_even", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO141p_odd"]}, "metabolites": {"nadh_x": 6.0, "tdecoa_x": -1.0, "h2o2_x": 5.0, "accoa_x": 7.0, "h_x": 6.0, "nad_x": -6.0, "h2o_x": -6.0, "o2_x": -5.0, "coa_x": -6.0}, "id": "FAO141p_odd", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO161p_even"]}, "metabolites": {"nadh_x": 7.0, "nad_x": -7.0, "h2o2_x": 7.0, "accoa_x": 8.0, "h_x": 6.0, "coa_x": -7.0, "h2o_x": -7.0, "nadp_x": 1.0, "hdcoa_x": -1.0, "o2_x": -7.0, "nadph_x": -1.0}, "id": "FAO161p_even", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO161p_odd"]}, "metabolites": {"nadh_x": 7.0, "nad_x": -7.0, "h2o2_x": 6.0, "accoa_x": 8.0, "h_x": 7.0, "coa_x": -7.0, "h2o_x": -7.0, "hdcoa_x": -1.0, "o2_x": -6.0}, "id": "FAO161p_odd", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO181p_even"]}, "metabolites": {"nadh_x": 8.0, "h2o2_x": 8.0, "accoa_x": 9.0, "h_x": 7.0, "nad_x": -8.0, "nadp_x": 1.0, "odecoa_x": -1.0, "h2o_x": -8.0, "o2_x": -8.0, "coa_x": -8.0, "nadph_x": -1.0}, "id": "FAO181p_even", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO181p_odd"]}, "metabolites": {"nadh_x": 8.0, "nad_x": -8.0, "h2o2_x": 7.0, "accoa_x": 9.0, "h_x": 8.0, "coa_x": -8.0, "odecoa_x": -1.0, "h2o_x": -8.0, "o2_x": -7.0}, "id": "FAO181p_odd", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO182p_even_FSLASH_even"]}, "metabolites": {"nadh_x": 8.0, "nad_x": -8.0, "h2o2_x": 8.0, "ocdycacoa_x": -1.0, "accoa_x": 9.0, "h_x": 6.0, "coa_x": -8.0, "nadp_x": 2.0, "h2o_x": -8.0, "o2_x": -8.0, "nadph_x": -2.0}, "id": "FAO182p_eveneven", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO182p_even_FSLASH_odd"]}, "metabolites": {"nadh_x": 8.0, "h2o2_x": 7.0, "ocdycacoa_x": -1.0, "nad_x": -8.0, "h_x": 7.0, "coa_x": -8.0, "accoa_x": 9.0, "nadp_x": 1.0, "h2o_x": -8.0, "o2_x": -7.0, "nadph_x": -1.0}, "id": "FAO182p_evenodd", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO182p_odd_FSLASH_odd"]}, "metabolites": {"nadh_x": 8.0, "h2o2_x": 6.0, "ocdycacoa_x": -1.0, "accoa_x": 9.0, "h_x": 8.0, "nad_x": -8.0, "h2o_x": -8.0, "o2_x": -6.0, "coa_x": -8.0}, "id": "FAO182p_oddodd", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation tetradecansoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO240p"]}, "metabolites": {"nadh_x": 3.0, "nad_x": -3.0, "stcoa_x": 1.0, "accoa_x": 3.0, "h_x": 3.0, "coa_x": -3.0, "ttccoa_x": -1.0, "h2o_x": -3.0, "o2_x": -3.0, "h2o2_x": 3.0}, "id": "FAO240p", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "Fatty acid oxidation octanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAO80p"]}, "metabolites": {"nadh_x": 3.0, "nad_x": -3.0, "occoa_x": -1.0, "h2o2_x": 3.0, "accoa_x": 4.0, "h_x": 3.0, "coa_x": -3.0, "h2o_x": -3.0, "o2_x": -3.0}, "id": "FAO80p", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid synthase n C100 ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS100"]}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "octa_c": -1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "dca_c": 1.0, "co2_c": 1.0}, "id": "FAS100", "gene_reaction_rule": "YGR037C and YNR016C and (YKL182W and YPL231W)"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP synthase n C100ACP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS100ACPm"]}, "metabolites": {"malACP_m": -1.0, "ACP_m": 1.0, "h2o_m": 1.0, "nadph_m": -2.0, "dcaACP_m": 1.0, "nadp_m": 2.0, "co2_m": 1.0, "h_m": -3.0, "ocACP_m": -1.0}, "id": "FAS100ACPm", "gene_reaction_rule": "YKL192C and YER061C and YKL055C and YOR221C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl CoA synthase n C100CoA ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS100COA"]}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "co2_c": 1.0, "occoa_c": -1.0, "dcacoa_c": 1.0}, "id": "FAS100COA", "gene_reaction_rule": "YGR037C and (YKL182W and YPL231W) and YNR016C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid synthase n C120 ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS120"]}, "metabolites": {"h2o_c": 1.0, "nadp_c": 2.0, "nadph_c": -2.0, "ddca_c": 1.0, "malcoa_c": -1.0, "coa_c": 1.0, "h_c": -3.0, "dca_c": -1.0, "co2_c": 1.0}, "id": "FAS120", "gene_reaction_rule": "YGR037C and YNR016C and (YKL182W and YPL231W)"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP synthase n C120ACP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS120ACPm"]}, "metabolites": {"malACP_m": -1.0, "ACP_m": 1.0, "dcaACP_m": -1.0, "nadph_m": -2.0, "h2o_m": 1.0, "nadp_m": 2.0, "co2_m": 1.0, "ddcaACP_m": 1.0, "h_m": -3.0}, "id": "FAS120ACPm", "gene_reaction_rule": "YKL192C and YER061C and YKL055C and YOR221C"}, {"subsystem": "Folate Metabolism", "name": "5 formethyltetrahydrofolate cyclo ligase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FTHFCL"]}, "metabolites": {"5fthf_c": -1.0, "pi_c": 1.0, "atp_c": -1.0, "adp_c": 1.0, "methf_c": 1.0}, "id": "FTHFCL", "gene_reaction_rule": "YER183C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl CoA synthase n C120CoA ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS120COA"]}, "metabolites": {"h2o_c": 1.0, "nadp_c": 2.0, "nadph_c": -2.0, "ddcacoa_c": 1.0, "malcoa_c": -1.0, "coa_c": 1.0, "h_c": -3.0, "co2_c": 1.0, "dcacoa_c": -1.0}, "id": "FAS120COA", "gene_reaction_rule": "YGR037C and YNR016C and (YKL182W and YPL231W)"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid synthase n C140 ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS140"]}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "ddca_c": -1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "co2_c": 1.0, "ttdca_c": 1.0}, "id": "FAS140", "gene_reaction_rule": "YGR037C and (YKL182W and YPL231W) and YNR016C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP synthase n C140ACP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS140ACPm"]}, "metabolites": {"malACP_m": -1.0, "ACP_m": 1.0, "nadph_m": -2.0, "h2o_m": 1.0, "nadp_m": 2.0, "co2_m": 1.0, "myrsACP_m": 1.0, "ddcaACP_m": -1.0, "h_m": -3.0}, "id": "FAS140ACPm", "gene_reaction_rule": "YKL192C and YER061C and YKL055C and YOR221C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl CoA synthase n C140CoA ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS140COA"]}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "ddcacoa_c": -1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "co2_c": 1.0, "tdcoa_c": 1.0}, "id": "FAS140COA", "gene_reaction_rule": "YGR037C and YNR016C and (YKL182W and YPL231W)"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP synthase n C141ACP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS141ACPm"]}, "metabolites": {"malACP_m": -1.0, "ACP_m": 1.0, "tdeACP_m": 1.0, "nadph_m": -3.0, "h2o_m": 3.0, "nadp_m": 3.0, "o2_m": -1.0, "co2_m": 1.0, "ddcaACP_m": -1.0, "h_m": -4.0}, "id": "FAS141ACPm", "gene_reaction_rule": "YKL192C and YER061C and YKL055C and YOR221C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid synthase n C160 ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS160"]}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "co2_c": 1.0, "hdca_c": 1.0, "ttdca_c": -1.0}, "id": "FAS160", "gene_reaction_rule": "YGR037C and (YKL182W and YPL231W) and YNR016C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP synthase n C160ACP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS160ACPm"]}, "metabolites": {"malACP_m": -1.0, "ACP_m": 1.0, "nadph_m": -2.0, "h2o_m": 1.0, "nadp_m": 2.0, "co2_m": 1.0, "myrsACP_m": -1.0, "palmACP_m": 1.0, "h_m": -3.0}, "id": "FAS160ACPm", "gene_reaction_rule": "YKL192C and YKL055C and YER061C and YOR221C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl CoA synthase n C160CoA ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS160COA"]}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "pmtcoa_c": 1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "co2_c": 1.0, "tdcoa_c": -1.0}, "id": "FAS160COA", "gene_reaction_rule": "YGR037C and (YKL182W and YPL231W) and YNR016C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP synthase n C161ACP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS161ACPm"]}, "metabolites": {"malACP_m": -1.0, "ACP_m": 1.0, "nadph_m": -3.0, "h2o_m": 3.0, "nadp_m": 3.0, "o2_m": -1.0, "hdeACP_m": 1.0, "co2_m": 1.0, "myrsACP_m": -1.0, "h_m": -4.0}, "id": "FAS161ACPm", "gene_reaction_rule": "YKL192C and YKL055C and YER061C and YOR221C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid synthase n C180 ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS180"]}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "ocdca_c": 1.0, "co2_c": 1.0, "hdca_c": -1.0}, "id": "FAS180", "gene_reaction_rule": "YGR037C and YNR016C and (YKL182W and YPL231W)"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP synthase n C180ACP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS180ACPm"]}, "metabolites": {"malACP_m": -1.0, "ACP_m": 1.0, "nadph_m": -2.0, "h2o_m": 1.0, "nadp_m": 2.0, "ocdcaACP_m": 1.0, "co2_m": 1.0, "palmACP_m": -1.0, "h_m": -3.0}, "id": "FAS180ACPm", "gene_reaction_rule": "YKL192C and YER061C and YKL055C and YOR221C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl CoA synthase n C180CoA ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS180COA"]}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "pmtcoa_c": -1.0, "stcoa_c": 1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "co2_c": 1.0}, "id": "FAS180COA", "gene_reaction_rule": "YGR037C and YNR016C and (YKL182W and YPL231W)"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP synthase n C181ACP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS181ACPm"]}, "metabolites": {"malACP_m": -1.0, "octeACP_m": 1.0, "ACP_m": 1.0, "nadph_m": -3.0, "h2o_m": 3.0, "nadp_m": 3.0, "o2_m": -1.0, "co2_m": 1.0, "palmACP_m": -1.0, "h_m": -4.0}, "id": "FAS181ACPm", "gene_reaction_rule": "YKL192C and YKL055C and YER061C and YOR221C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP synthase n C182ACP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS182ACPm"]}, "metabolites": {"malACP_m": -1.0, "ACP_m": 1.0, "nadph_m": -4.0, "h2o_m": 5.0, "nadp_m": 4.0, "ocdcyaACP_m": 1.0, "o2_m": -2.0, "co2_m": 1.0, "palmACP_m": -1.0, "h_m": -5.0}, "id": "FAS182ACPm", "gene_reaction_rule": "YKL192C and YKL055C and YER061C and YOR221C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid synthase n C240 lumped reaction", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS240_L"]}, "metabolites": {"h2o_c": 3.0, "malcoa_c": -3.0, "nadph_c": -6.0, "ttc_c": 1.0, "nadp_c": 6.0, "coa_c": 3.0, "h_c": -9.0, "ocdca_c": -1.0, "co2_c": 3.0}, "id": "FAS240_L", "gene_reaction_rule": "YCR034W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid synthase n C260 ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS260"]}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "ttc_c": -1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "hexc_c": 1.0, "co2_c": 1.0}, "id": "FAS260", "gene_reaction_rule": "YLR372W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl ACP synthase n C80ACP mitochondrial lumped reaction", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS80ACPm_L"]}, "metabolites": {"malACP_m": -3.0, "ACP_m": 3.0, "acACP_m": -1.0, "nadph_m": -6.0, "h2o_m": 3.0, "nadp_m": 6.0, "co2_m": 3.0, "h_m": -9.0, "ocACP_m": 1.0}, "id": "FAS80ACPm_L", "gene_reaction_rule": "YKL192C and YER061C and YKL055C and YOR221C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acyl CoA synthase n C80CoA lumped reaction", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS80COA_L"]}, "metabolites": {"h2o_c": 3.0, "nadp_c": 6.0, "nadph_c": -6.0, "malcoa_c": -3.0, "coa_c": 3.0, "h_c": -9.0, "accoa_c": -1.0, "co2_c": 3.0, "occoa_c": 1.0}, "id": "FAS80COA_L", "gene_reaction_rule": "YGR037C and (YKL182W and YPL231W) and YNR016C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Fatty acid synthase n C80 lumped reaction", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FAS80_L"]}, "metabolites": {"h2o_c": 2.0, "malcoa_c": -3.0, "nadph_c": -6.0, "octa_c": 1.0, "nadp_c": 6.0, "coa_c": 4.0, "h_c": -8.0, "accoa_c": -1.0, "co2_c": 3.0}, "id": "FAS80_L", "gene_reaction_rule": "YGR037C and YNR016C and (YKL182W and YPL231W)"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Fructose-bisphosphate aldolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FBA"]}, "metabolites": {"dhap_c": 1.0, "g3p_c": 1.0, "fdp_c": -1.0}, "id": "FBA", "gene_reaction_rule": "YKL060C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "D Fructose 1 phosphate D glyceraldehyde 3 phosphate lyase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FBA2"]}, "metabolites": {"f1p_c": -1.0, "dhap_c": 1.0, "glyald_c": 1.0}, "id": "FBA2", "gene_reaction_rule": "YKL060C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Sedoheptulose 1,7-bisphosphate D-glyceraldehyde-3-phosphate-lyase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FBA3"]}, "metabolites": {"e4p_c": 1.0, "dhap_c": 1.0, "s17bp_c": -1.0}, "id": "FBA3", "gene_reaction_rule": "YKL060C"}, {"subsystem": "Anaplerotic reactions", "name": "Fructose-bisphosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FBP"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "fdp_c": -1.0, "f6p_c": 1.0}, "id": "FBP", "gene_reaction_rule": "YLR377C"}, {"subsystem": "Fructose and Mannose Metabolism", "name": "Fructose 2 6 bisphosphate 2 phosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FBP26"]}, "metabolites": {"f26bp_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "f6p_c": 1.0}, "id": "FBP26", "gene_reaction_rule": "YJL155C"}, {"subsystem": "Porphyrin and Chlorophyll Metabolism", "name": "Ferrochelatase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FCLTm"]}, "metabolites": {"pheme_m": 1.0, "h_m": 2.0, "fe2_m": -1.0, "ppp9_m": -1.0}, "id": "FCLTm", "gene_reaction_rule": "YOR176W"}, {"subsystem": "Methane Metabolism", "name": "Formate dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FDH"]}, "metabolites": {"co2_c": 1.0, "nadh_c": 1.0, "for_c": -1.0, "nad_c": -1.0}, "id": "FDH", "gene_reaction_rule": "YPL275W or YPL276W or YOR388C"}, {"subsystem": "Oxidative Phosphorylation", "name": "Formate dehydrogenase cytosolicmitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FDNG"]}, "metabolites": {"q6_m": -1.0, "co2_c": 1.0, "h_c": -1.0, "for_c": -1.0, "q6h2_m": 1.0}, "id": "FDNG", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "N Formyl L kynurenine amidohydrolase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FKYNH"]}, "metabolites": {"Lfmkynr_c": -1.0, "h2o_c": -1.0, "h_c": 1.0, "for_c": 1.0, "Lkynr_c": 1.0}, "id": "FKYNH", "gene_reaction_rule": ""}, {"subsystem": "Folate Metabolism", "name": "Methionyl tRNA formyltransferase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FMETTRSm"]}, "metabolites": {"mettrna_m": -1.0, "fmettrna_m": 1.0, "h_m": 1.0, "thf_m": 1.0, "10fthf_m": -1.0}, "id": "FMETTRSm", "gene_reaction_rule": "YBL013W"}, {"subsystem": "Riboflavin Metabolism", "name": "FMN adenylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FMNAT"]}, "metabolites": {"ppi_c": 1.0, "fmn_c": -1.0, "fad_c": 1.0, "atp_c": -1.0, "h_c": -1.0}, "id": "FMNAT", "gene_reaction_rule": "YDL045C"}, {"subsystem": "Riboflavin Metabolism", "name": "FMN adenylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FMNATm"]}, "metabolites": {"atp_m": -1.0, "fad_m": 1.0, "fmn_m": -1.0, "h_m": -1.0, "ppi_m": 1.0}, "id": "FMNATm", "gene_reaction_rule": ""}, {"subsystem": "Folate Metabolism", "name": "Dihydropteroate synthase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FOLD3m"]}, "metabolites": {"ppi_m": 1.0, "4abz_m": -1.0, "2ahhmd_m": -1.0, "dhpt_m": 1.0}, "id": "FOLD3m", "gene_reaction_rule": "YNL256W"}, {"subsystem": "Transport, Extracellular", "name": "Formate transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FORt"]}, "metabolites": {"for_e": -1.0, "for_c": 1.0}, "id": "FORt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Formate mitochondrial transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FORtm"]}, "metabolites": {"for_m": -1.0, "for_c": 1.0}, "id": "FORtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Fumarate reductase cytosolicmitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FRDcm"]}, "metabolites": {"fad_m": 1.0, "succ_c": 1.0, "fum_c": -1.0, "fadh2_m": -1.0}, "id": "FRDcm", "gene_reaction_rule": "YEL047C"}, {"subsystem": "Oxidative Phosphorylation", "name": "Fumarate reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FRDm"]}, "metabolites": {"fad_m": 1.0, "succ_m": 1.0, "fadh2_m": -1.0, "fum_m": -1.0}, "id": "FRDm", "gene_reaction_rule": "YJR051W"}, {"subsystem": "Fructose and Mannose Metabolism", "name": "Fructose-1-phosphate kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FRUK"]}, "metabolites": {"adp_c": 1.0, "f1p_c": -1.0, "h_c": 1.0, "atp_c": -1.0, "fdp_c": 1.0}, "id": "FRUK", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "D fructose transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FRUt2"]}, "metabolites": {"fru_e": -1.0, "h_e": -1.0, "h_c": 1.0, "fru_c": 1.0}, "id": "FRUt2", "gene_reaction_rule": "YJR158W or YHR096C or YOL156W or YNR072W or YDR345C or YDR343C or YFL011W or YJL219W or YJL214W or YMR011W or YHR094C or YEL069C or YDR342C or YHR092C or YDL245C"}, {"subsystem": "Folate Metabolism", "name": "5 formethyltetrahydrofolate cyclo ligase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FTHFCLm"]}, "metabolites": {"atp_m": -1.0, "adp_m": 1.0, "methf_m": 1.0, "pi_m": 1.0, "5fthf_m": -1.0}, "id": "FTHFCLm", "gene_reaction_rule": ""}, {"subsystem": "Folate Metabolism", "name": "FTHFI", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FTHFI"]}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "adp_c": 1.0, "5fthf_c": -1.0, "pi_c": 1.0, "10fthf_c": 1.0}, "id": "FTHFI_1", "gene_reaction_rule": ""}, {"subsystem": "Folate Metabolism", "name": "Formate-tetrahydrofolate ligase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FTHFL"]}, "metabolites": {"for_c": -1.0, "atp_c": -1.0, "thf_c": -1.0, "adp_c": 1.0, "pi_c": 1.0, "10fthf_c": 1.0}, "id": "FTHFLi", "gene_reaction_rule": "YGR204W"}, {"subsystem": "Folate Metabolism", "name": "Formate tetrahydrofolate ligase mitochondrial irreversible", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FTHFLm"]}, "metabolites": {"atp_m": -1.0, "adp_m": 1.0, "10fthf_m": 1.0, "pi_m": 1.0, "for_m": -1.0, "thf_m": -1.0}, "id": "FTHFLmi", "gene_reaction_rule": "YBR084W"}, {"subsystem": "Oxidative Phosphorylation", "name": "Fumarase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FUM"]}, "metabolites": {"h2o_c": -1.0, "fum_c": -1.0, "mal__L_c": 1.0}, "id": "FUM", "gene_reaction_rule": "YPL262W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Fumarylacetoacetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FUMAC"]}, "metabolites": {"acac_c": 1.0, "4fumacac_c": -1.0, "h2o_c": -1.0, "fum_c": 1.0, "h_c": 1.0}, "id": "FUMAC", "gene_reaction_rule": ""}, {"subsystem": "Oxidative Phosphorylation", "name": "Fumarase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FUMm"]}, "metabolites": {"mal__L_m": 1.0, "h2o_m": -1.0, "fum_m": -1.0}, "id": "FUMm", "gene_reaction_rule": "YPL262W"}, {"subsystem": "Transport, Extracellular", "name": "Fumarate reversible transport via symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["FUMt2r"]}, "metabolites": {"fum_c": 1.0, "h_e": -1.0, "h_c": 1.0, "fum_e": -1.0}, "id": "FUMt2r", "gene_reaction_rule": ""}, {"subsystem": "Glycoprotein Metabolism", "name": "Glycolipid 1 2 alpha D mannosyltransferase Golgi apparatus", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G12MT1g"]}, "metabolites": {"gdp_g": 1.0, "h_g": 1.0, "m2macchitppdol_g": -1.0, "m3macchitppdol_g": 1.0, "gdpmann_g": -1.0}, "id": "G12MT1g", "gene_reaction_rule": "YNL029C or YKR061W or YPL053C or YOR099W or YJL139C or YDR483W or YBR205W or YBR199W"}, {"subsystem": "Glycoprotein Metabolism", "name": "Glycolipid 1 2 alpha D mannosyltransferase Golgi apparatus", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G12MT2g"]}, "metabolites": {"gdp_g": 1.0, "h_g": 1.0, "m4macchitppdol_g": 1.0, "gdpmann_g": -1.0, "m3macchitppdol_g": -1.0}, "id": "G12MT2g", "gene_reaction_rule": "YNL029C or YKR061W or YPL053C or YOR099W or YJL139C or YDR483W or YBR205W or YBR199W"}, {"subsystem": "Glycoprotein Metabolism", "name": "Glycolipid 1 3 alpha D mannosyltransferase Golgi apparatus", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G13MTg"]}, "metabolites": {"gdp_g": 1.0, "h_g": 1.0, "m1macchitppdol_g": 1.0, "macchitppdol_g": -1.0, "gdpmann_g": -1.0}, "id": "G13MTg", "gene_reaction_rule": ""}, {"subsystem": "Glycoprotein Metabolism", "name": "Glycolipid 1 6 alpha D mannosyltransferase Golgi apparatus", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G16MTg"]}, "metabolites": {"gdp_g": 1.0, "h_g": 1.0, "m2macchitppdol_g": 1.0, "m1macchitppdol_g": -1.0, "gdpmann_g": -1.0}, "id": "G16MTg", "gene_reaction_rule": ""}, {"subsystem": "Glycerolipid Metabolism", "name": "Glycerol 3 phosphate dehydrogenase NAD ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G3PD1ir"]}, "metabolites": {"glyc3p_c": 1.0, "dhap_c": -1.0, "nadh_c": -1.0, "h_c": -1.0, "nad_c": 1.0}, "id": "G3PD1ir", "gene_reaction_rule": "YDL022W"}, {"subsystem": "Glycerolipid Metabolism", "name": "Glycerol 3 phosphate dehydrogenase NAD mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G3PD1irm"]}, "metabolites": {"nad_m": 1.0, "h_m": -1.0, "glyc3p_m": 1.0, "dhap_m": -1.0, "nadh_m": -1.0}, "id": "G3PD1irm", "gene_reaction_rule": "YOL059W"}, {"subsystem": "Glycerolipid Metabolism", "name": "Glycerol 3 phosphate dehydrogenase FAD mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G3PDm"]}, "metabolites": {"fad_m": -1.0, "glyc3p_m": -1.0, "fadh2_m": 1.0, "dhap_m": 1.0}, "id": "G3PDm", "gene_reaction_rule": "YIL155C"}, {"subsystem": "Glycerolipid Metabolism", "name": "Glycerol-3-phosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G3PT"]}, "metabolites": {"glyc3p_c": -1.0, "pi_c": 1.0, "glyc_c": 1.0, "h2o_c": -1.0}, "id": "G3PT", "gene_reaction_rule": "YIL053W or YER062C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "L-glutamate 5-semialdehyde dehydratase (spontaneous)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["G5SADr"]}, "metabolites": {"1pyr5c_c": 1.0, "glu5sa_c": -1.0, "h2o_c": 1.0, "h_c": 1.0}, "id": "G5SADs", "gene_reaction_rule": ""}, {"subsystem": "Arginine and Proline Metabolism", "name": "L glutamate 5 semialdehyde dehydratase reversible mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["G5SADrm"]}, "metabolites": {"h_m": 1.0, "h2o_m": 1.0, "1pyr5c_m": 1.0, "glu5sa_m": -1.0}, "id": "G5SADrm", "gene_reaction_rule": ""}, {"subsystem": "Arginine and Proline Metabolism", "name": "Glutamate-5-semialdehyde dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G5SD"]}, "metabolites": {"glu5sa_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "pi_c": 1.0, "glu5p_c": -1.0}, "id": "G5SD", "gene_reaction_rule": "YOR323C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Glutamate 5 semialdehyde dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G5SD2"]}, "metabolites": {"glu5sa_c": 1.0, "nadh_c": -1.0, "h_c": -1.0, "nad_c": 1.0, "pi_c": 1.0, "glu5p_c": -1.0}, "id": "G5SD2", "gene_reaction_rule": "YOR323C"}, {"subsystem": "Glucosamine Metabolism", "name": "Glucosamine-6-phosphate deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G6PDA"]}, "metabolites": {"gam6p_c": -1.0, "nh4_c": 1.0, "h2o_c": -1.0, "f6p_c": 1.0}, "id": "G6PDA", "gene_reaction_rule": ""}, {"subsystem": "Pentose Phosphate Pathway", "name": "Glucose 6-phosphate dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G6PDH2"]}, "metabolites": {"6pgl_c": 1.0, "g6p_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "h_c": 1.0}, "id": "G6PDH2r", "gene_reaction_rule": "YNL241C"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Glucose 6 phosphate dehydrogenase endoplasmic reticulum", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G6PDH2er"]}, "metabolites": {"6pgl_r": 1.0, "g6p_r": -1.0, "h_r": 1.0, "nadp_r": -1.0, "nadph_r": 1.0}, "id": "G6PDH2er", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Glucose 6 phosphate isomerase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["G6PI"]}, "metabolites": {"g6p_c": -1.0, "g6p_B_c": 1.0}, "id": "G6PI", "gene_reaction_rule": "YBR196C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "G6PI2", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["G6PI2"]}, "metabolites": {"g6p_B_c": -1.0, "f6p_B_c": 1.0}, "id": "G6PI2", "gene_reaction_rule": "YBR196C"}, {"subsystem": "Transport, Endoplasmic Reticular", "name": "Glucose 6 phosphate endoplasmic reticular transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["G6Pter"]}, "metabolites": {"g6p_c": -1.0, "g6p_r": 1.0}, "id": "G6Pter", "gene_reaction_rule": ""}, {"subsystem": "Galactose metabolism", "name": "1 alpha D Galactosyl myo inositol galactohydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GALIGH"]}, "metabolites": {"1Dgali_c": -1.0, "h2o_c": -1.0, "gal_c": 1.0, "inost_c": 1.0}, "id": "GALIGH", "gene_reaction_rule": "YBR184W"}, {"subsystem": "Galactose metabolism", "name": "Galactokinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GALK"]}, "metabolites": {"h_c": 1.0, "gal_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "gal1p_c": 1.0}, "id": "GALKr", "gene_reaction_rule": "YBR020W"}, {"subsystem": "Galactose metabolism", "name": "A-galactosidase (melibiose)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GALS3"]}, "metabolites": {"glc__D_c": 1.0, "melib_c": -1.0, "gal_c": 1.0, "h2o_c": -1.0}, "id": "GALS3", "gene_reaction_rule": "YBR184W"}, {"subsystem": "Galactose metabolism", "name": "Galactose 1 phosphate uridylyltransferase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GALT"]}, "metabolites": {"udpgal_c": 1.0, "utp_c": -1.0, "ppi_c": 1.0, "gal1p_c": -1.0, "h_c": -1.0}, "id": "GALT", "gene_reaction_rule": "YBR018C"}, {"subsystem": "Galactose metabolism", "name": "UTP-glucose-1-phosphate uridylyltransferase (irreversible)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GALU"]}, "metabolites": {"utp_c": -1.0, "ppi_c": 1.0, "udpg_c": 1.0, "h_c": -1.0, "g1p_c": -1.0}, "id": "GALUi", "gene_reaction_rule": "YKL035W or YHL012W"}, {"subsystem": "Transport, Extracellular", "name": "D galactose transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GALt2"]}, "metabolites": {"gal_c": 1.0, "h_e": -1.0, "h_c": 1.0, "gal_e": -1.0}, "id": "GALt2", "gene_reaction_rule": "YDR536W or YNL318C or YLR081W or YOL156W or YFL011W or YJL219W"}, {"subsystem": "Transport, Extracellular", "name": "D glucosamine 6 phosphate reversible uniport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GAM6Pt"]}, "metabolites": {"gam6p_c": 1.0, "gam6p_e": -1.0}, "id": "GAM6Pt", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GAPD"]}, "metabolites": {"nadh_c": 1.0, "13dpg_c": 1.0, "g3p_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "pi_c": -1.0}, "id": "GAPD", "gene_reaction_rule": "YJL052W or YGR192C or YJR009C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Phosphoribosylglycinamide formyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GARFTi"]}, "metabolites": {"gar_c": -1.0, "10fthf_c": -1.0, "fgam_c": 1.0, "h_c": 1.0, "thf_c": 1.0}, "id": "GARFT", "gene_reaction_rule": "YDR408C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Glycerol 3 phosphate acyltransferase glycerol 3 phosphate yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GAT1_SC"]}, "metabolites": {"glyc3p_c": -1.0, "odecoa_c": -0.24, "ddcacoa_c": -0.06, "hdcoa_c": -0.17, "pmtcoa_c": -0.27, "stcoa_c": -0.05, "coa_c": 1.0, "1ag3p_SC_c": 0.01, "ocdycacoa_c": -0.09, "dcacoa_c": -0.02, "tdcoa_c": -0.1}, "id": "GAT1_SC", "gene_reaction_rule": ""}, {"subsystem": "Phospholipid Biosynthesis", "name": "Glycerol 3 phosphate acyltransferase glycerone phosphate yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GAT2_SC"]}, "metabolites": {"hdcoa_c": -0.17, "odecoa_c": -0.24, "ddcacoa_c": -0.06, "dhap_c": -1.0, "pmtcoa_c": -0.27, "stcoa_c": -0.05, "coa_c": 1.0, "ocdycacoa_c": -0.09, "1agly3p_SC_c": 0.01, "dcacoa_c": -0.02, "tdcoa_c": -0.1}, "id": "GAT2_SC", "gene_reaction_rule": ""}, {"subsystem": "Alternate Carbon Metabolism", "name": "1 4 alpha glucan branching enzyme", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GBEZ"]}, "metabolites": {"h2o_c": 1.0, "14glun_c": -1.0, "glycogen_c": 1.0}, "id": "GBEZ", "gene_reaction_rule": "YEL011W"}, {"subsystem": "Transport, Extracellular", "name": "Glycoaldehydye reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GCALDt"]}, "metabolites": {"gcald_e": -1.0, "gcald_c": 1.0}, "id": "GCALDt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Glycoaldehyde mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GCALDtm"]}, "metabolites": {"gcald_m": 1.0, "gcald_c": -1.0}, "id": "GCALDtm", "gene_reaction_rule": ""}, {"subsystem": "Glycine and Serine Metabolism", "name": "Glycine cleavage complex lipoamide mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GCC2am"]}, "metabolites": {"lpam_m": -1.0, "alpam_m": 1.0, "gly_m": -1.0, "h_m": -1.0, "co2_m": 1.0}, "id": "GCC2am", "gene_reaction_rule": "YDR019C and YMR189W and YFL018C and YAL044C"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Glycine cleavage system lipoamide irreversible mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GCC2bim"]}, "metabolites": {"mlthf_m": 1.0, "thf_m": -1.0, "nh4_m": 1.0, "alpam_m": -1.0, "dhlam_m": 1.0}, "id": "GCC2bim", "gene_reaction_rule": "YDR019C and YMR189W and YFL018C and YAL044C"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Glycine cleavage complex lipoamide mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GCC2cm", "PDHcm"]}, "metabolites": {"lpam_m": 1.0, "nad_m": -1.0, "h_m": 1.0, "nadh_m": 1.0, "dhlam_m": -1.0}, "id": "GCC2cm_copy1", "gene_reaction_rule": "YMR189W and YDR019C and YFL018C and YAL044C"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Glycine cleavage complex lipoylprotein mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GCCam"]}, "metabolites": {"gly_m": -1.0, "h_m": -1.0, "co2_m": 1.0, "lpro_m": -1.0, "alpro_m": 1.0}, "id": "GCCam", "gene_reaction_rule": "YMR189W and YDR019C and YFL018C and YAL044C"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Glycine cleavage complex lipoylprotein irreversible mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GCCbim"]}, "metabolites": {"mlthf_m": 1.0, "dhlpro_m": 1.0, "nh4_m": 1.0, "thf_m": -1.0, "alpro_m": -1.0}, "id": "GCCbim", "gene_reaction_rule": "YDR019C and YMR189W and YFL018C and YAL044C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Gnnuc", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GNNUC"]}, "metabolites": {"gua_c": 1.0, "h2o_c": -1.0, "rib__D_c": 1.0, "gsn_c": -1.0}, "id": "GNNUC", "gene_reaction_rule": "YDR400W"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Glycine cleavage complex lipoylprotein mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GCCcm"]}, "metabolites": {"nad_m": -1.0, "dhlpro_m": -1.0, "h_m": 1.0, "lpro_m": 1.0, "nadh_m": 1.0}, "id": "GCCcm", "gene_reaction_rule": "YMR189W and YDR019C and YFL018C and YAL044C"}, {"subsystem": "Transport, Golgi Apparatus", "name": "GDP Golgi transport via proton anitport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GDPt3g"]}, "metabolites": {"gdp_g": -1.0, "h_g": 1.0, "gdp_c": 1.0, "h_c": -1.0}, "id": "GDPt3g", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "GDP nuclear transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GDPtn"]}, "metabolites": {"gdp_n": 1.0, "gdp_c": -1.0}, "id": "GDPtn", "gene_reaction_rule": ""}, {"subsystem": "Glutamine Metabolism", "name": "Glutamine-fructose-6-phosphate transaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GF6PTA"]}, "metabolites": {"gam6p_c": 1.0, "gln__L_c": -1.0, "glu__L_c": 1.0, "f6p_c": -1.0}, "id": "GF6PTA", "gene_reaction_rule": "YKL104C or YMR085W or YMR084W"}, {"subsystem": "Galactose metabolism", "name": "Galactosylglycerol galactohydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GGLGH"]}, "metabolites": {"h2o_c": -1.0, "gal_c": 1.0, "ggl_c": -1.0, "glyc_c": 1.0}, "id": "GGLGH", "gene_reaction_rule": "YBR184W"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Glycine hydroxymethyltransferase, reversible", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GHMT2r"]}, "metabolites": {"h2o_c": 1.0, "ser__L_c": -1.0, "gly_c": 1.0, "mlthf_c": 1.0, "thf_c": -1.0}, "id": "GHMT2r", "gene_reaction_rule": "YLR058C"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Glycine hydroxymethyltransferase reversible mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GHMT2rm"]}, "metabolites": {"mlthf_m": 1.0, "h2o_m": 1.0, "thf_m": -1.0, "ser__L_m": -1.0, "gly_m": 1.0}, "id": "GHMT2rm", "gene_reaction_rule": "YBR263W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Guanylate kinase (GMP:ATP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GK1"]}, "metabolites": {"gmp_c": -1.0, "gdp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "GK1", "gene_reaction_rule": "YDR454C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Guanylate kinase GMPdATP ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GK2"]}, "metabolites": {"dadp_c": 1.0, "gmp_c": -1.0, "gdp_c": 1.0, "datp_c": -1.0}, "id": "GK2", "gene_reaction_rule": "YDR454C"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Glycogen phosphorylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLCP"]}, "metabolites": {"pi_c": -1.0, "glycogen_c": -1.0, "g1p_c": 1.0}, "id": "GLCP", "gene_reaction_rule": "YPR160W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Glycogen synthase UDPGlc ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLCS2"]}, "metabolites": {"udp_c": 1.0, "udpg_c": -1.0, "h_c": 1.0, "glycogen_c": 1.0}, "id": "GLCS2", "gene_reaction_rule": "YLR258W or YFR015C"}, {"subsystem": "Transport, Extracellular", "name": "Glucose transport uniport ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLCt1"]}, "metabolites": {"glc__D_c": 1.0, "glc__D_e": -1.0}, "id": "GLCt1", "gene_reaction_rule": "YMR011W or YDL245C or YJL219W or YLR081W or YHR092C or YJL214W or YHR096C or YEL069C or YOL156W or YFL011W or YDR345C or YDR343C or YDR342C or YJR158W or YDR536W or YNR072W or YHR094C"}, {"subsystem": "Transport, Vacuolar", "name": "Glucose transport vacuolar", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLCtv"]}, "metabolites": {"glc__D_c": -1.0, "glc__D_v": 1.0}, "id": "GLCtv", "gene_reaction_rule": ""}, {"subsystem": "Glutamine Metabolism", "name": "Glutamine synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLNS"]}, "metabolites": {"atp_c": -1.0, "glu__L_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0, "nh4_c": -1.0, "gln__L_c": 1.0}, "id": "GLNS", "gene_reaction_rule": "YPR035W"}, {"subsystem": "Glutamine Metabolism", "name": "Glutaminyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLNTRS"]}, "metabolites": {"glntrna_c": 1.0, "atp_c": -1.0, "trnagln_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "gln__L_c": -1.0}, "id": "GLNTRS", "gene_reaction_rule": "YOR168W"}, {"subsystem": "Transport, Nuclear", "name": "Glutamine nuclear transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLNt2n"]}, "metabolites": {"h_n": 1.0, "gln__L_n": 1.0, "h_c": -1.0, "gln__L_c": -1.0}, "id": "GLNt2n", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L glutamine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLNt2r"]}, "metabolites": {"gln__L_e": -1.0, "h_e": -1.0, "h_c": 1.0, "gln__L_c": 1.0}, "id": "GLNt2r", "gene_reaction_rule": "YDR508C or YCL025C or YKR039W or YPL265W"}, {"subsystem": "Other Amino Acid Metabolism", "name": "Glycylpeptide N tetradecanoyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLPT"]}, "metabolites": {"glp_c": -1.0, "tglp_c": 1.0, "coa_c": 1.0, "tdcoa_c": -1.0}, "id": "GLPT", "gene_reaction_rule": "YLR195C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Glutamate 5-kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLU5K"]}, "metabolites": {"glu__L_c": -1.0, "glu5p_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "GLU5K", "gene_reaction_rule": "YDR300C"}, {"subsystem": "Other Amino Acid Metabolism", "name": "Gamma-glutamylcysteine synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUCYS"]}, "metabolites": {"cys__L_c": -1.0, "glucys_c": 1.0, "atp_c": -1.0, "glu__L_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "GLUCYS", "gene_reaction_rule": "YJL101C"}, {"subsystem": "Glutamate metabolism", "name": "Glutamate Decarboxylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUDC"]}, "metabolites": {"glu__L_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "4abut_c": 1.0}, "id": "GLUDC", "gene_reaction_rule": "YMR250W"}, {"subsystem": "Glutamate metabolism", "name": "Glutamate dehydrogenase NAD ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUDxi"]}, "metabolites": {"akg_c": 1.0, "h2o_c": -1.0, "glu__L_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0, "nh4_c": 1.0}, "id": "GLUDxi", "gene_reaction_rule": "YDL215C"}, {"subsystem": "Glutamate metabolism", "name": "Glutamate dehydrogenase (NADP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLUDy"]}, "metabolites": {"akg_c": 1.0, "h2o_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "glu__L_c": -1.0, "h_c": 1.0, "nh4_c": 1.0}, "id": "GLUDy", "gene_reaction_rule": "YAL062W or YOR375C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Glucokinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUK"]}, "metabolites": {"glc__D_c": -1.0, "g6p_B_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "GLUK", "gene_reaction_rule": "YCL040W"}, {"subsystem": "Glutamine Metabolism", "name": "Glutaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUN"]}, "metabolites": {"glu__L_c": 1.0, "nh4_c": 1.0, "h2o_c": -1.0, "gln__L_c": -1.0}, "id": "GLUN", "gene_reaction_rule": ""}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Glutamine phosphoribosyldiphosphate amidotransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUPRT"]}, "metabolites": {"pram_c": 1.0, "h2o_c": -1.0, "ppi_c": 1.0, "glu__L_c": 1.0, "prpp_c": -1.0, "gln__L_c": -1.0}, "id": "GLUPRT", "gene_reaction_rule": "YMR300C"}, {"subsystem": "Glutamate metabolism", "name": "Glutamate synthase NADH2 ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUSx"]}, "metabolites": {"akg_c": -1.0, "glu__L_c": 2.0, "h_c": -1.0, "nad_c": 1.0, "nadh_c": -1.0, "gln__L_c": -1.0}, "id": "GLUSx", "gene_reaction_rule": "YDL171C"}, {"subsystem": "Glutamine Metabolism", "name": "Glutamyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUTRS"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "trnaglu_c": -1.0, "amp_c": 1.0, "glutrna_c": 1.0, "glu__L_c": -1.0}, "id": "GLUTRS", "gene_reaction_rule": "YGL245W"}, {"subsystem": "Glutamine Metabolism", "name": "Glutamyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUTRSm"]}, "metabolites": {"trnaglu_m": -1.0, "ppi_m": 1.0, "atp_m": -1.0, "glutrna_m": 1.0, "glu__L_m": -1.0, "amp_m": 1.0}, "id": "GLUTRSm", "gene_reaction_rule": "YOL033W"}, {"subsystem": "Transport, Mitochondrial", "name": "GLUt2m", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLUt2m"]}, "metabolites": {"glu__L_c": -1.0, "h_m": 1.0, "glu__L_m": 1.0, "h_c": -1.0}, "id": "GLUt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "Glutamate nuclear transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLUt2n"]}, "metabolites": {"h_n": 1.0, "glu__L_c": -1.0, "h_c": -1.0, "glu__L_n": 1.0}, "id": "GLUt2n", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L glutamate transport via proton symport reversible", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLUt2r"]}, "metabolites": {"glu__L_c": 1.0, "h_e": -1.0, "glu__L_e": -1.0, "h_c": 1.0}, "id": "GLUt2r", "gene_reaction_rule": "YCL025C or YFL055W or YKR039W or YDR536W or YPL265W"}, {"subsystem": "Transport, Mitochondrial", "name": "L glutamate transport into mitochondria via hydroxide ion antiport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUt5m"]}, "metabolites": {"oh1_c": 1.0, "glu__L_c": -1.0, "glu__L_m": 1.0, "oh1_m": -1.0}, "id": "GLUt5m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Glyoxylate transport peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLXtp"]}, "metabolites": {"glx_c": -1.0, "glx_x": 1.0}, "id": "GLXtp", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Glycerol 3 phosphate shuttle", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLYC3Ptm"]}, "metabolites": {"glyc3p_c": -1.0, "glyc3p_m": 1.0}, "id": "GLYC3Ptm", "gene_reaction_rule": ""}, {"subsystem": "Glycine and Serine Metabolism", "name": "Glycine cleavage system mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLYCLm"]}, "metabolites": {"mlthf_m": 1.0, "gly_m": -1.0, "nadh_m": 1.0, "nh4_m": 1.0, "nad_m": -1.0, "thf_m": -1.0, "co2_m": 1.0}, "id": "GLYCLm", "gene_reaction_rule": "YMR189W and YFL018C and YDR019C and YAL044C"}, {"subsystem": "Transport, Extracellular", "name": "Glycerol transport via channel", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLYCt"]}, "metabolites": {"glyc_e": 1.0, "glyc_c": -1.0}, "id": "GLYCt", "gene_reaction_rule": "YLL043W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Glycogen starch synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLYGS"]}, "metabolites": {"udp_c": 1.0, "udpg_c": -1.0, "h_c": 1.0, "h2o_c": -1.0, "14glun_c": 1.0}, "id": "GLYGS", "gene_reaction_rule": "YFR015C or YLR258W"}, {"subsystem": "Glycerolipid Metabolism", "name": "Glycerol kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLYK"]}, "metabolites": {"adp_c": 1.0, "glyc3p_c": 1.0, "h_c": 1.0, "atp_c": -1.0, "glyc_c": -1.0}, "id": "GLYK", "gene_reaction_rule": "YHL032C"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Hydroxyacylglutathione hydrolase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLYOX"]}, "metabolites": {"lgt__S_c": -1.0, "gthrd_c": 1.0, "lac__D_c": 1.0, "h_c": 1.0, "h2o_c": -1.0}, "id": "GLYOX", "gene_reaction_rule": "YDR272W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Hydroxyacylglutathione hydrolase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLYOXm"]}, "metabolites": {"gthrd_m": 1.0, "h_m": 1.0, "h2o_m": -1.0, "lgt__S_m": -1.0, "lac__D_m": 1.0}, "id": "GLYOXm", "gene_reaction_rule": "YOR040W"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Glycyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLYTRS"]}, "metabolites": {"glytrna_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "trnagly_c": -1.0, "amp_c": 1.0, "gly_c": -1.0}, "id": "GLYTRS", "gene_reaction_rule": "YPR081C or YBR121C"}, {"subsystem": "Transport, Mitochondrial", "name": "Glycine mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLYt2m"]}, "metabolites": {"gly_m": 1.0, "h_m": 1.0, "h_c": -1.0, "gly_c": -1.0}, "id": "GLYt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Glycine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GLYt2r"]}, "metabolites": {"gly_e": -1.0, "h_e": -1.0, "h_c": 1.0, "gly_c": 1.0}, "id": "GLYt2r", "gene_reaction_rule": "YPL265W or YKR039W or YOR348C or YOL020W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "GMP synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GMPS2"]}, "metabolites": {"xmp_c": -1.0, "h2o_c": -1.0, "gmp_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "gln__L_c": -1.0, "glu__L_c": 1.0, "h_c": 2.0}, "id": "GMPS2", "gene_reaction_rule": "YMR217W"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Phosphogluconate dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GND"]}, "metabolites": {"6pgc_c": -1.0, "co2_c": 1.0, "nadph_c": 1.0, "nadp_c": -1.0, "ru5p__D_c": 1.0}, "id": "GND", "gene_reaction_rule": "YGR256W or YHR183W"}, {"subsystem": "Sterol Biosynthesis", "name": "Geranyltranstransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GRTT"]}, "metabolites": {"ppi_c": 1.0, "ipdp_c": -1.0, "frdp_c": 1.0, "grdp_c": -1.0}, "id": "GRTT", "gene_reaction_rule": "YJL167W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Guanosine kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GSNK"]}, "metabolites": {"h_c": 1.0, "gmp_c": 1.0, "atp_c": -1.0, "adp_c": 1.0, "gsn_c": -1.0}, "id": "GSNK", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Guanosine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GSNt2"]}, "metabolites": {"gsn_e": -1.0, "h_e": -1.0, "h_c": 1.0, "gsn_c": 1.0}, "id": "GSNt2", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Guanosine mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GSNt2m"]}, "metabolites": {"gsn_m": 1.0, "h_m": 1.0, "h_c": -1.0, "gsn_c": -1.0}, "id": "GSNt2m", "gene_reaction_rule": ""}, {"subsystem": "Other Amino Acid Metabolism", "name": "Glutathione oxidoreductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GTHO"]}, "metabolites": {"nadph_c": -1.0, "nadp_c": 1.0, "gthrd_c": 2.0, "h_c": -1.0, "gthox_c": -1.0}, "id": "GTHOr", "gene_reaction_rule": "YPL091W"}, {"subsystem": "Transport, Extracellular", "name": "Oxidized glutathione irreversible uniport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GTHOXti"]}, "metabolites": {"gthox_e": -1.0, "gthox_c": 1.0}, "id": "GTHOXti", "gene_reaction_rule": ""}, {"subsystem": "Other Amino Acid Metabolism", "name": "Glutathione peridoxase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GTHP"]}, "metabolites": {"h2o2_c": -1.0, "h2o_c": 2.0, "gthrd_c": -2.0, "gthox_c": 1.0}, "id": "GTHPi", "gene_reaction_rule": "YBR244W or YKL026C or YIR037W"}, {"subsystem": "Other Amino Acid Metabolism", "name": "Glutathione synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GTHS"]}, "metabolites": {"pi_c": 1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "glucys_c": -1.0, "gthrd_c": 1.0, "gly_c": -1.0}, "id": "GTHS", "gene_reaction_rule": "YOL049W"}, {"subsystem": "Other Amino Acid Metabolism", "name": "G glutamyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GTMLT"]}, "metabolites": {"ala__L_c": -1.0, "gthrd_c": -1.0, "gluala_c": 1.0, "cgly_c": 1.0}, "id": "GTMLT", "gene_reaction_rule": "YLR299W"}, {"subsystem": "Folate Metabolism", "name": "GTPCI", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GTPCI"]}, "metabolites": {"h2o_c": -1.0, "gtp_c": -1.0, "for_c": 1.0, "ahdt_c": 1.0}, "id": "GTPCI_1", "gene_reaction_rule": "YGR267C"}, {"subsystem": "Riboflavin Metabolism", "name": "GTP cyclohydrolase II", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GTPCII"]}, "metabolites": {"h2o_c": -3.0, "ppi_c": 1.0, "gtp_c": -1.0, "25dhpp_c": 1.0, "for_c": 1.0, "h_c": 2.0}, "id": "GTPCII", "gene_reaction_rule": "YBL033C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Guanine phosphoribosyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GUAPRT"]}, "metabolites": {"gua_c": -1.0, "gmp_c": 1.0, "ppi_c": 1.0, "prpp_c": -1.0}, "id": "GUAPRT", "gene_reaction_rule": "YDR399W"}, {"subsystem": "Transport, Extracellular", "name": "Guanine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GUAt2r"]}, "metabolites": {"gua_c": 1.0, "h_e": -1.0, "gua_e": -1.0, "h_c": 1.0}, "id": "GUAt2r", "gene_reaction_rule": "YGL186C or YER056C or YER060W or YER060W_A"}, {"subsystem": "Transport, Mitochondrial", "name": "Guanine mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["GUAtm"]}, "metabolites": {"gua_c": -1.0, "gua_m": 1.0}, "id": "GUAtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "H2O transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["H2Ot"]}, "metabolites": {"h2o_c": 1.0, "h2o_e": -1.0}, "id": "H2Ot", "gene_reaction_rule": ""}, {"subsystem": "Transport, Endoplasmic Reticular", "name": "H2O endoplasmic reticulum transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["H2Oter"]}, "metabolites": {"h2o_c": -1.0, "h2o_r": 1.0}, "id": "H2Oter", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "H2O transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["H2Otm"]}, "metabolites": {"h2o_c": -1.0, "h2o_m": 1.0}, "id": "H2Otm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "H2O transport nuclear", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["H2Otn"]}, "metabolites": {"h2o_c": 1.0, "h2o_n": -1.0}, "id": "H2Otn", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "H2O transport peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["H2Otp"]}, "metabolites": {"h2o_x": 1.0, "h2o_c": -1.0}, "id": "H2Otp", "gene_reaction_rule": ""}, {"subsystem": "Transport, Vacuolar", "name": "H2O transport vacuolar", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["H2Otv"]}, "metabolites": {"h2o_c": -1.0, "h2o_v": 1.0}, "id": "H2Otv", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydrogenase 3 oxohexacosyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HACD10p"]}, "metabolites": {"nadh_x": 1.0, "3ohxccoa_x": 1.0, "3hxccoa_x": -1.0, "h_x": 1.0, "nad_x": -1.0}, "id": "HACD10p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydrogenase 3 oxodecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HACD4p"]}, "metabolites": {"3odcoa_x": -1.0, "nadh_x": -1.0, "nad_x": 1.0, "h_x": -1.0, "3hdcoa_x": 1.0}, "id": "HACD4p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydrogenase 3 oxodecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HACD5p"]}, "metabolites": {"3hddcoa_x": 1.0, "3oddcoa_x": -1.0, "nadh_x": -1.0, "nad_x": 1.0, "h_x": -1.0}, "id": "HACD5p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Degradation", "name": "3 Hydroxyacyl CoA dehydrogenase 3 oxotetradecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HACD6p"]}, "metabolites": {"3htdcoa_x": 1.0, "nadh_x": -1.0, "nad_x": 1.0, "h_x": -1.0, "3otdcoa_x": -1.0}, "id": "HACD6p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydrogenase 3 oxohexadecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HACD7p"]}, "metabolites": {"nadh_x": -1.0, "3hhdcoa_x": 1.0, "3ohdcoa_x": -1.0, "h_x": -1.0, "nad_x": 1.0}, "id": "HACD7p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Degradation", "name": "3 hydroxyacyl CoA dehydrogenase 3 oxooctadecanoyl CoA peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HACD8p"]}, "metabolites": {"nadh_x": -1.0, "3hodcoa_x": 1.0, "3ohodcoa_x": -1.0, "h_x": -1.0, "nad_x": 1.0}, "id": "HACD8p", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "HACDp", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HACDp"]}, "metabolites": {"nadh_x": 1.0, "3oacoa_x": 1.0, "3hacoa_x": -1.0, "nad_x": -1.0, "h_x": 1.0}, "id": "HACDp", "gene_reaction_rule": "YKR009C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "Homoacontinate hydratase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HACNHm"]}, "metabolites": {"hicit_m": 1.0, "b124tc_m": -1.0, "h2o_m": -1.0}, "id": "HACNHm", "gene_reaction_rule": "YDR234W"}, {"subsystem": "Quinone Biosynthesis", "name": "HBZOPT6", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HBZOPT6"]}, "metabolites": {"4hbz_c": -1.0, "ppi_c": 1.0, "octdp_5_c": -1.0, "3ophb_5_c": 1.0}, "id": "HBZOPT6", "gene_reaction_rule": "(YDL090C and YKL019W) or (YGL155W and YKL019W) or YMR101C or (YJL031C and YPR176C) or YBR002C"}, {"subsystem": "Quinone Biosynthesis", "name": "HBZOPT6m", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HBZOPT6m"]}, "metabolites": {"3ophb_5_m": 1.0, "octdp_5_m": -1.0, "ppi_m": 1.0, "4hbz_m": -1.0}, "id": "HBZOPT6m_1", "gene_reaction_rule": "YPL172C or YBR003W or YNR041C"}, {"subsystem": "Pyruvate Metabolism", "name": "Homocitrate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HCITSm"]}, "metabolites": {"hcit_m": 1.0, "h2o_m": -1.0, "akg_m": -1.0, "accoa_m": -1.0, "coa_m": 1.0, "h_m": 1.0}, "id": "HCITSm", "gene_reaction_rule": ""}, {"subsystem": "Pyruvate Metabolism", "name": "Homocitrate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HCITSn"]}, "metabolites": {"hcit_n": 1.0, "akg_n": -1.0, "h2o_n": -1.0, "h_n": 1.0, "coa_n": 1.0, "accoa_n": -1.0}, "id": "HCITSn", "gene_reaction_rule": "YDL182W or YDL131W"}, {"subsystem": "--", "name": "HCO3 equilibration reaction", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HCO3E"]}, "metabolites": {"hco3_c": 1.0, "h2o_c": -1.0, "co2_c": -1.0, "h_c": 1.0}, "id": "HCO3E", "gene_reaction_rule": ""}, {"subsystem": "--", "name": "HCO3 equilibration reaction", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HCO3Em"]}, "metabolites": {"h_m": 1.0, "h2o_m": -1.0, "co2_m": -1.0, "hco3_m": 1.0}, "id": "HCO3Em", "gene_reaction_rule": ""}, {"subsystem": "--", "name": "HCO3 equilibrium reaction nuclear", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HCO3En"]}, "metabolites": {"h_n": 1.0, "hco3_n": 1.0, "co2_n": -1.0, "h2o_n": -1.0}, "id": "HCO3En", "gene_reaction_rule": ""}, {"subsystem": "Alanine and Aspartate Metabolism", "name": "Homocysteine S-methyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HCYSMT"]}, "metabolites": {"hcys__L_c": -1.0, "amet_c": -1.0, "ahcys_c": 1.0, "h_c": 1.0, "met__L_c": 1.0}, "id": "HCYSMT", "gene_reaction_rule": "YLL062C or YPL273W"}, {"subsystem": "Transport, Peroxisomal", "name": "Homocysteine peroxisomal transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HCYSt2p"]}, "metabolites": {"hcys__L_c": -1.0, "hcys__L_x": 1.0, "h_c": -1.0, "h_x": 1.0}, "id": "HCYSt2p", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Hexadecanoate n C160 transport in via uniport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HDCAt"]}, "metabolites": {"hdca_e": -1.0, "hdca_c": 1.0}, "id": "HDCAt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Hexadecenoate n C161 transport in via uniport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HDCEAt"]}, "metabolites": {"hdcea_c": 1.0, "hdcea_e": -1.0}, "id": "HDCEAt", "gene_reaction_rule": ""}, {"subsystem": "Thiamine Metabolism", "name": "Hydroxyethylthiazole kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HETZK"]}, "metabolites": {"4mhetz_c": -1.0, "4mpetz_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "HETZK", "gene_reaction_rule": "YPL214C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Hexokinase (D-glucose:ATP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HEX1"]}, "metabolites": {"glc__D_c": -1.0, "g6p_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "HEX1", "gene_reaction_rule": "YFR053C or YCL040W or YGL253W"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Hexokinase (D-mannose:ATP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HEX4"]}, "metabolites": {"h_c": 1.0, "man6p_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "man_c": -1.0}, "id": "HEX4", "gene_reaction_rule": "YFR053C or YGL253W"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Hexokinase (D-fructose:ATP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HEX7"]}, "metabolites": {"h_c": 1.0, "fru_c": -1.0, "atp_c": -1.0, "adp_c": 1.0, "f6p_c": 1.0}, "id": "HEX7", "gene_reaction_rule": "YGL253W or YFR053C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Homogentisateoxygen 1 2 oxidoreductase decyclizing ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HGNTOR"]}, "metabolites": {"o2_c": -1.0, "4mlacac_c": 1.0, "h_c": 1.0, "hgentis_c": -1.0}, "id": "HGNTOR", "gene_reaction_rule": ""}, {"subsystem": "Threonine and Lysine Metabolism", "name": "Homoisocitrate dehydrogenase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HICITDm"]}, "metabolites": {"nad_m": -1.0, "oxag_m": 1.0, "hicit_m": -1.0, "nadh_m": 1.0, "h_m": 1.0}, "id": "HICITDm", "gene_reaction_rule": "YIL094C"}, {"subsystem": "Histidine Metabolism", "name": "Histidinol dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HISTD"]}, "metabolites": {"histd_c": -1.0, "h2o_c": -1.0, "his__L_c": 1.0, "h_c": 3.0, "nad_c": -2.0, "nadh_c": 2.0}, "id": "HISTD", "gene_reaction_rule": "YCL030C"}, {"subsystem": "Histidine Metabolism", "name": "Histidinol-phosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HISTP"]}, "metabolites": {"hisp_c": -1.0, "histd_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0}, "id": "HISTP", "gene_reaction_rule": "YFR025C"}, {"subsystem": "Histidine Metabolism", "name": "Histidyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HISTRS"]}, "metabolites": {"histrna_c": 1.0, "atp_c": -1.0, "his__L_c": -1.0, "ppi_c": 1.0, "trnahis_c": -1.0, "amp_c": 1.0}, "id": "HISTRS", "gene_reaction_rule": "YPR033C"}, {"subsystem": "Histidine Metabolism", "name": "Histidyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HISTRSm"]}, "metabolites": {"trnahis_m": -1.0, "ppi_m": 1.0, "his__L_m": -1.0, "atp_m": -1.0, "histrna_m": 1.0, "amp_m": 1.0}, "id": "HISTRSm", "gene_reaction_rule": "YPR033C"}, {"subsystem": "Transport, Mitochondrial", "name": "Histidine mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HISt2m"]}, "metabolites": {"his__L_c": 1.0, "h_m": -1.0, "h_c": 1.0, "his__L_m": -1.0}, "id": "HISt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L histidine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HISt2r"]}, "metabolites": {"his__L_c": 1.0, "h_e": -1.0, "h_c": 1.0, "his__L_e": -1.0}, "id": "HISt2r", "gene_reaction_rule": "YCL025C or YKR039W or YGR191W or YBR069C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "3 Hydroxy L kynurenine hydrolase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HKYNH"]}, "metabolites": {"3hanthrn_c": 1.0, "hLkynr_c": -1.0, "ala__L_c": 1.0, "h2o_c": -1.0}, "id": "HKYNH", "gene_reaction_rule": "YLR231C"}, {"subsystem": "Porphyrin and Chlorophyll Metabolism", "name": "Hydroxymethylbilane synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HMBS"]}, "metabolites": {"ppbng_c": -4.0, "hmbil_c": 1.0, "h2o_c": -1.0, "nh4_c": 4.0}, "id": "HMBS", "gene_reaction_rule": "YDL205C"}, {"subsystem": "Sterol Biosynthesis", "name": "Hydroxymethylglutaryl CoA reductase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HMGCOAR"]}, "metabolites": {"nadp_c": -2.0, "nadph_c": 2.0, "hmgcoa_c": 1.0, "mev__R_c": -1.0, "coa_c": -1.0, "h_c": 2.0}, "id": "HMGCOAR", "gene_reaction_rule": "YLR450W or YML075C"}, {"subsystem": "Sterol Biosynthesis", "name": "Hydroxymethylglutaryl CoA synthase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HMGCOAS"]}, "metabolites": {"h2o_c": 1.0, "aacoa_c": 1.0, "hmgcoa_c": -1.0, "coa_c": -1.0, "h_c": -1.0, "accoa_c": 1.0}, "id": "HMGCOAS", "gene_reaction_rule": "YML126C"}, {"subsystem": "Sterol Biosynthesis", "name": "Hydroxymethylglutaryl CoA synthase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HMGCOASm"]}, "metabolites": {"h2o_m": 1.0, "accoa_m": 1.0, "coa_m": -1.0, "h_m": -1.0, "aacoa_m": 1.0, "hmgcoa_m": -1.0}, "id": "HMGCOASm", "gene_reaction_rule": "YML126C"}, {"subsystem": "Transport, Mitochondrial", "name": "Hydroxymethylglutaryl CoA reversible mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HMGCOAtm"]}, "metabolites": {"hmgcoa_c": -1.0, "hmgcoa_m": 1.0}, "id": "HMGCOAtm", "gene_reaction_rule": ""}, {"subsystem": "Thiamine Metabolism", "name": "Hydroxymethylpyrimidine kinase (ATP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HMPK1"]}, "metabolites": {"4ampm_c": 1.0, "4ahmmp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "HMPK1", "gene_reaction_rule": "YOL055C or YPL258C or YPR121W"}, {"subsystem": "Folate Metabolism", "name": "2 amino 4 hydroxy 6 hydroxymethyldihydropteridine diphosphokinase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HPPKm"]}, "metabolites": {"atp_m": -1.0, "2ahhmp_m": -1.0, "amp_m": 1.0, "h_m": 1.0, "2ahhmd_m": 1.0}, "id": "HPPKm", "gene_reaction_rule": "YNL256W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "L hydroxyproline reductase NAD ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HPROa"]}, "metabolites": {"4hpro_LT_c": 1.0, "nadh_c": -1.0, "1p3h5c_c": -1.0, "h_c": -2.0, "nad_c": 1.0}, "id": "HPROa", "gene_reaction_rule": "YER023W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "L hydroxyproline reductase NADP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HPROb"]}, "metabolites": {"nadph_c": -1.0, "nadp_c": 1.0, "1p3h5c_c": -1.0, "h_c": -2.0, "4hpro_LT_c": 1.0}, "id": "HPROb", "gene_reaction_rule": "YER023W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "L hydroxyproline dehydrogenase NAD mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HPROxm"]}, "metabolites": {"nad_m": -1.0, "4hpro_LT_m": -1.0, "h_m": 2.0, "nadh_m": 1.0, "1p3h5c_m": 1.0}, "id": "HPROxm", "gene_reaction_rule": "YHR037W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "L hydroxyproline dehydrogenase NADP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HPROym"]}, "metabolites": {"nadph_m": 1.0, "h_m": 2.0, "4hpro_LT_m": -1.0, "nadp_m": -1.0, "1p3h5c_m": 1.0}, "id": "HPROym", "gene_reaction_rule": "YHR037W"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Homoserine dehydrogenase NADH irreversible", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HSDxi"]}, "metabolites": {"hom__L_c": 1.0, "aspsa_c": -1.0, "nadh_c": -1.0, "h_c": -1.0, "nad_c": 1.0}, "id": "HSDxi", "gene_reaction_rule": "YJR139C"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Homoserine dehydrogenase NADP irreversible", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HSDyi"]}, "metabolites": {"hom__L_c": 1.0, "aspsa_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0}, "id": "HSDyi", "gene_reaction_rule": "YJR139C"}, {"subsystem": "Methionine Metabolism", "name": "Homoserine O trans acetylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HSERTA"]}, "metabolites": {"hom__L_c": -1.0, "coa_c": 1.0, "achms_c": 1.0, "accoa_c": -1.0}, "id": "HSERTA", "gene_reaction_rule": "YNL277W"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Homoserine kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HSK"]}, "metabolites": {"phom_c": 1.0, "hom__L_c": -1.0, "h_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "HSK", "gene_reaction_rule": "YHR025W"}, {"subsystem": "Histidine Metabolism", "name": "Histidinol-phosphate transaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HSTPT"]}, "metabolites": {"akg_c": 1.0, "hisp_c": 1.0, "glu__L_c": -1.0, "imacp_c": -1.0}, "id": "HSTPT", "gene_reaction_rule": "YIL116W"}, {"subsystem": "Transport, Extracellular", "name": "Hypoxanthine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["HXANt2r"]}, "metabolites": {"hxan_e": -1.0, "h_e": -1.0, "h_c": 1.0, "hxan_c": 1.0}, "id": "HXANt2r", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Hypoxanthine phosphoribosyltransferase (Hypoxanthine)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HXPRT"]}, "metabolites": {"ppi_c": 1.0, "hxan_c": -1.0, "prpp_c": -1.0, "imp_c": 1.0}, "id": "HXPRT", "gene_reaction_rule": "YDR399W"}, {"subsystem": "Pyridoxine Metabolism", "name": "Hypothetical enyme", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["HYPOE"]}, "metabolites": {"pydam_c": 1.0, "pyam5p_c": -1.0, "pi_c": 1.0, "h2o_c": -1.0}, "id": "HYPOE", "gene_reaction_rule": ""}, {"subsystem": "Citric Acid Cycle", "name": "Isocitrate dehydrogenase NAD ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ICDHxm"]}, "metabolites": {"nad_m": -1.0, "co2_m": 1.0, "icit_m": -1.0, "akg_m": 1.0, "nadh_m": 1.0}, "id": "ICDHxm", "gene_reaction_rule": "YOR136W and YNL037C"}, {"subsystem": "Citric Acid Cycle", "name": "Isocitrate dehydrogenase (NADP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ICDHy"]}, "metabolites": {"akg_c": 1.0, "co2_c": 1.0, "icit_c": -1.0, "nadph_c": 1.0, "nadp_c": -1.0}, "id": "ICDHyr", "gene_reaction_rule": "YLR174W"}, {"subsystem": "Citric Acid Cycle", "name": "Isocitrate dehydrogenase NADP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ICDHym"]}, "metabolites": {"co2_m": 1.0, "nadph_m": 1.0, "nadp_m": -1.0, "akg_m": 1.0, "icit_m": -1.0}, "id": "ICDHym", "gene_reaction_rule": "YDL066W"}, {"subsystem": "Citric Acid Cycle", "name": "Isocitrate dehydrogenase NADP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ICDHyp"]}, "metabolites": {"co2_x": 1.0, "nadp_x": -1.0, "icit_x": -1.0, "akg_x": 1.0, "nadph_x": 1.0}, "id": "ICDHyp", "gene_reaction_rule": "YNL009W"}, {"subsystem": "Anaplerotic reactions", "name": "Isocitrate lyase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ICL"]}, "metabolites": {"succ_c": 1.0, "icit_c": -1.0, "glx_c": 1.0}, "id": "ICL", "gene_reaction_rule": "YER065C"}, {"subsystem": "Transport, Mitochondrial", "name": "Indole 3 acetaldehyde mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ID3ACALDtm"]}, "metabolites": {"id3acald_m": 1.0, "id3acald_c": -1.0}, "id": "ID3ACALDtm", "gene_reaction_rule": ""}, {"subsystem": "Histidine Metabolism", "name": "Imidazole-glycerol-3-phosphate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IG3PS"]}, "metabolites": {"aicar_c": 1.0, "glu__L_c": 1.0, "eig3p_c": 1.0, "h_c": 1.0, "prlp_c": -1.0, "gln__L_c": -1.0}, "id": "IG3PS", "gene_reaction_rule": "YBR248C"}, {"subsystem": "Histidine Metabolism", "name": "Imidazoleglycerol-phosphate dehydratase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IGPDH"]}, "metabolites": {"h2o_c": 1.0, "imacp_c": 1.0, "eig3p_c": -1.0}, "id": "IGPDH", "gene_reaction_rule": "YOR202W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Indole-3-glycerol-phosphate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IGPS"]}, "metabolites": {"h2o_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "2cpr5p_c": -1.0, "3ig3p_c": 1.0}, "id": "IGPS", "gene_reaction_rule": "YKL211C"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Isoleucine transaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ILETA"]}, "metabolites": {"akg_c": -1.0, "3mop_c": 1.0, "glu__L_c": 1.0, "ile__L_c": -1.0}, "id": "ILETA", "gene_reaction_rule": "YJR148W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Isoleucine transaminase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ILETAm"]}, "metabolites": {"glu__L_m": 1.0, "akg_m": -1.0, "ile__L_m": -1.0, "3mop_m": 1.0}, "id": "ILETAm", "gene_reaction_rule": "YHR208W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Isoleucyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ILETRS"]}, "metabolites": {"iletrna_c": 1.0, "trnaile_c": -1.0, "atp_c": -1.0, "ile__L_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0}, "id": "ILETRS", "gene_reaction_rule": "YBL076C"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Isoleucyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ILETRSm"]}, "metabolites": {"ppi_m": 1.0, "ile__L_m": -1.0, "atp_m": -1.0, "trnaile_m": -1.0, "iletrna_m": 1.0, "amp_m": 1.0}, "id": "ILETRSm", "gene_reaction_rule": "YPL040C"}, {"subsystem": "Transport, Extracellular", "name": "L isoleucine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ILEt2r"]}, "metabolites": {"ile__L_c": 1.0, "h_e": -1.0, "h_c": 1.0, "ile__L_e": -1.0}, "id": "ILEt2r", "gene_reaction_rule": "YCL025C or YKR039W or YBR069C or YBR068C or YDR046C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "IMP cyclohydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["IMPC"]}, "metabolites": {"h2o_c": -1.0, "fprica_c": 1.0, "imp_c": -1.0}, "id": "IMPC", "gene_reaction_rule": "YLR028C or YMR120C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "IMP dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IMPD"]}, "metabolites": {"xmp_c": 1.0, "h2o_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0, "imp_c": -1.0}, "id": "IMPD", "gene_reaction_rule": "YAR073W or YML056C or YLR432W or YHR216W or YAR075W"}, {"subsystem": "Transport, Mitochondrial", "name": "Indole 3 acetate mitochondrial transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["IND3ACtm"]}, "metabolites": {"ind3ac_m": 1.0, "ind3ac_c": -1.0}, "id": "IND3ACtm", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Indole 3 pyruvate decarboxylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["INDPYRD"]}, "metabolites": {"indpyr_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "id3acald_c": 1.0}, "id": "INDPYRD", "gene_reaction_rule": "YDR380W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Insosine kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["INSK"]}, "metabolites": {"imp_c": 1.0, "ins_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "INSK", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Inositol transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["INSTt2"]}, "metabolites": {"inost_e": -1.0, "h_e": -1.0, "inost_c": 1.0, "h_c": 1.0}, "id": "INSTt2", "gene_reaction_rule": "YDR497C or YOL103W"}, {"subsystem": "Transport, Extracellular", "name": "Inosine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["INSt2"]}, "metabolites": {"ins_e": -1.0, "h_e": -1.0, "h_c": 1.0, "ins_c": 1.0}, "id": "INSt2", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid Metabolism", "name": "Inositol phosphorylceramide synthase ceramide 1 24C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IPCS124_SC"]}, "metabolites": {"12dgr_SC_c": 0.01, "cer1_24_c": -1.0, "ptd1ino_SC_c": -0.01, "ipc124_SC_c": 0.01}, "id": "IPCS124_SC", "gene_reaction_rule": "YKL004W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Inositol phosphorylceramide synthase ceramide 1 26C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IPCS126_SC"]}, "metabolites": {"12dgr_SC_c": 0.01, "cer1_26_c": -1.0, "ptd1ino_SC_c": -0.01, "ipc126_SC_c": 0.01}, "id": "IPCS126_SC", "gene_reaction_rule": "YKL004W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Inositol phosphorylceramide synthase ceramide 2 24C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IPCS224_SC"]}, "metabolites": {"12dgr_SC_c": 0.01, "cer2_24_c": -1.0, "ptd1ino_SC_c": -0.01, "ipc224_SC_c": 0.01}, "id": "IPCS224_SC", "gene_reaction_rule": "YKL004W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Inositol phosphoryceramide synthase ceramide 2 26C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IPCS226_SC"]}, "metabolites": {"ipc226_SC_c": 0.01, "cer2_26_c": -1.0, "ptd1ino_SC_c": -0.01, "12dgr_SC_c": 0.01}, "id": "IPCS226_SC", "gene_reaction_rule": "YKL004W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Inositol phosphorylceramide synthase ceramide 3 24C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IPCS324_SC"]}, "metabolites": {"12dgr_SC_c": 0.01, "cer3_24_c": -1.0, "ptd1ino_SC_c": -0.01, "ipc324_SC_c": 0.01}, "id": "IPCS324_SC", "gene_reaction_rule": "YKL004W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Inositol phosphorylceramide synthase ceramide 3 26C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IPCS326_SC"]}, "metabolites": {"12dgr_SC_c": 0.01, "cer3_26_c": -1.0, "ptd1ino_SC_c": -0.01, "ipc326_SC_c": 0.01}, "id": "IPCS326_SC", "gene_reaction_rule": "YKL004W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "3-isopropylmalate dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IPMD"]}, "metabolites": {"3c4mop_c": 1.0, "3c2hmp_c": -1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0}, "id": "IPMD", "gene_reaction_rule": "YCL018W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "3-isopropylmalate dehydratase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["IPPMIa"]}, "metabolites": {"3c2hmp_c": -1.0, "h2o_c": 1.0, "2ippm_c": 1.0}, "id": "IPPMIa", "gene_reaction_rule": "YGL009C"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "2-isopropylmalate hydratase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["IPPMIb"]}, "metabolites": {"2ippm_c": -1.0, "h2o_c": -1.0, "3c3hmp_c": 1.0}, "id": "IPPMIb", "gene_reaction_rule": "YGL009C"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "2-isopropylmalate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IPPS"]}, "metabolites": {"h2o_c": -1.0, "3c3hmp_c": 1.0, "3mob_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "accoa_c": -1.0}, "id": "IPPS", "gene_reaction_rule": "YOR108W or YNL104C"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "2 isopropylmalate synthase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["IPPSm"]}, "metabolites": {"3mob_m": -1.0, "h2o_m": -1.0, "accoa_m": -1.0, "3c3hmp_m": 1.0, "coa_m": 1.0, "h_m": 1.0}, "id": "IPPSm", "gene_reaction_rule": "YNL104C"}, {"subsystem": "Citric Acid Cycle", "name": "Itaconate CoA ligase ADP forming mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ITCOALm"]}, "metabolites": {"itaccoa_m": 1.0, "atp_m": -1.0, "adp_m": 1.0, "pi_m": 1.0, "itacon_m": -1.0, "coa_m": -1.0}, "id": "ITCOALm", "gene_reaction_rule": "YOR142W and YGR244C"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Acetohydroxy acid isomeroreductase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["KARA1im"]}, "metabolites": {"23dhmb_m": 1.0, "alac__S_m": -1.0, "nadph_m": -1.0, "h_m": -1.0, "nadp_m": 1.0}, "id": "KARA1im", "gene_reaction_rule": "YLR355C"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Ketol acid reductoisomerase 2 Aceto 2 hydroxybutanoate mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["KARA2im"]}, "metabolites": {"nadph_m": -1.0, "2ahbut_m": -1.0, "h_m": -1.0, "nadp_m": 1.0, "23dhmp_m": 1.0}, "id": "KARA2im", "gene_reaction_rule": "YLR355C"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "KATp", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["KATp"]}, "metabolites": {"3oacoa_x": -1.0, "coa_x": -1.0, "accoa_x": 1.0, "acoa_x": 1.0}, "id": "KATp", "gene_reaction_rule": "YIL160C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Kynureninase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["KYN"]}, "metabolites": {"anth_c": 1.0, "h2o_c": -1.0, "ala__L_c": 1.0, "h_c": 1.0, "Lkynr_c": -1.0}, "id": "KYN", "gene_reaction_rule": "YLR231C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Kynurenine 3 monooxygenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["KYN3OX"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "hLkynr_c": 1.0, "h_c": -1.0, "Lkynr_c": -1.0}, "id": "KYN3OX", "gene_reaction_rule": "YBL098W"}, {"subsystem": "Transport, Extracellular", "name": "Potassium reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["Kt2r"]}, "metabolites": {"k_c": 1.0, "h_e": -1.0, "k_e": -1.0, "h_c": 1.0}, "id": "Kt2r", "gene_reaction_rule": ""}, {"subsystem": "Other Amino Acid Metabolism", "name": "LCADm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["LCADm"]}, "metabolites": {"lac__L_m": 1.0, "lald__L_m": -1.0, "h2o_m": -1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0}, "id": "LCADm", "gene_reaction_rule": "YER073W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Leucine transaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["LEUTA"]}, "metabolites": {"akg_c": -1.0, "glu__L_c": 1.0, "4mop_c": 1.0, "leu__L_c": -1.0}, "id": "LEUTA", "gene_reaction_rule": "YJR148W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Leucine transaminase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["LEUTAm"]}, "metabolites": {"leu__L_m": -1.0, "4mop_m": 1.0, "glu__L_m": 1.0, "akg_m": -1.0}, "id": "LEUTAm", "gene_reaction_rule": "YHR208W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Leucyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LEUTRS"]}, "metabolites": {"leutrna_c": 1.0, "leu__L_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "trnaleu_c": -1.0}, "id": "LEUTRS", "gene_reaction_rule": "YPL160W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Leucyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LEUTRSm"]}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "leu__L_m": -1.0, "leutrna_m": 1.0, "trnaleu_m": -1.0, "amp_m": 1.0}, "id": "LEUTRSm", "gene_reaction_rule": "YLR382C"}, {"subsystem": "Transport, Extracellular", "name": "L leucine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["LEUt2r"]}, "metabolites": {"leu__L_c": 1.0, "h_e": -1.0, "leu__L_e": -1.0, "h_c": 1.0}, "id": "LEUt2r", "gene_reaction_rule": "YDR046C or YDR508C or YBR069C or YBR068C or YCL025C or YKR039W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Lactoylglutathione lyase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LGTHL"]}, "metabolites": {"gthrd_c": -1.0, "lgt__S_c": 1.0, "mthgxl_c": -1.0}, "id": "LGTHL", "gene_reaction_rule": "YML004C"}, {"subsystem": "Sterol Biosynthesis", "name": "Cytochrome P450 lanosterol 14 alpha demethylase NADP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LNS14DM"]}, "metabolites": {"o2_c": -3.0, "h2o_c": 4.0, "nadp_c": 3.0, "nadph_c": -3.0, "lanost_c": -1.0, "44mctr_c": 1.0, "h_c": -2.0, "for_c": 1.0}, "id": "LNS14DM", "gene_reaction_rule": "YHR007C"}, {"subsystem": "Sterol Biosynthesis", "name": "Lanosterol synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LNSTLS"]}, "metabolites": {"lanost_c": 1.0, "Ssq23epx_c": -1.0}, "id": "LNSTLS", "gene_reaction_rule": "YHR072W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Lipid phosphate phosphatase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LPP_SC"]}, "metabolites": {"h2o_c": -1.0, "pa_SC_c": 0.01, "h_c": 1.0, "dagpy_SC_c": -0.01, "pi_c": 1.0}, "id": "LPP_SC", "gene_reaction_rule": "YDR284C or YDR503C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "Lysyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LYSTRS"]}, "metabolites": {"trnalys_c": -1.0, "lys__L_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "lystrna_c": 1.0}, "id": "LYSTRS", "gene_reaction_rule": "YDR037W"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "Lysyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LYSTRSm"]}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "lys__L_m": -1.0, "trnalys_m": -1.0, "lystrna_m": 1.0, "amp_m": 1.0}, "id": "LYSTRSm", "gene_reaction_rule": "YNL073W"}, {"subsystem": "Transport, Mitochondrial", "name": "Lysine mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["LYSt2m"]}, "metabolites": {"lys__L_m": 1.0, "h_m": 1.0, "lys__L_c": -1.0, "h_c": -1.0}, "id": "LYSt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L lysine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["LYSt2r"]}, "metabolites": {"lys__L_e": -1.0, "h_e": -1.0, "lys__L_c": 1.0, "h_c": 1.0}, "id": "LYSt2r", "gene_reaction_rule": "YKR039W or YNL268W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "L LACDm", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["L_LACDm"]}, "metabolites": {"ficytc_m": -2.0, "lac__L_m": -1.0, "pyr_m": 1.0, "focytc_m": 2.0}, "id": "L_LACDm", "gene_reaction_rule": "YML054C"}, {"subsystem": "Transport, Extracellular", "name": "L lactate reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["L_LACt2r"]}, "metabolites": {"lac__L_e": -1.0, "h_e": -1.0, "lac__L_c": 1.0, "h_c": 1.0}, "id": "L_LACt2r", "gene_reaction_rule": "YKL217W"}, {"subsystem": "Mannitol Metabolism", "name": "Mannitol-1-phosphate 5-dehydrogenase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["M1PD"]}, "metabolites": {"nad_c": -1.0, "f6p_c": 1.0, "h_c": 1.0, "nadh_c": 1.0, "mnl1p_c": -1.0}, "id": "M1PD", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Maleylacetoacetate isomerase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MACACI"]}, "metabolites": {"4fumacac_c": 1.0, "4mlacac_c": -1.0}, "id": "MACACI", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Malateoxaloacetate shuttle", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MALOAAtp"]}, "metabolites": {"mal__L_x": -1.0, "mal__L_c": 1.0, "oaa_x": 1.0, "oaa_c": -1.0}, "id": "MALOAAtp", "gene_reaction_rule": ""}, {"subsystem": "Anaplerotic reactions", "name": "Malate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MALSp"]}, "metabolites": {"accoa_x": -1.0, "h_x": 1.0, "coa_x": 1.0, "mal__L_x": 1.0, "h2o_x": -1.0, "glx_x": -1.0}, "id": "MALSp", "gene_reaction_rule": "YIR031C or YNL117W"}, {"subsystem": "Galactose metabolism", "name": "Alpha glucosidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MALT"]}, "metabolites": {"glc__D_c": 2.0, "h2o_c": -1.0, "malt_c": -1.0}, "id": "MALT", "gene_reaction_rule": "YJL216C or YGR287C or YBR299W or YJL221C or YGR292W or YIL172C"}, {"subsystem": "Transport, Extracellular", "name": "Maltose transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MALTt2"]}, "metabolites": {"malt_c": 1.0, "h_e": -1.0, "malt_e": -1.0, "h_c": 1.0}, "id": "MALTt2", "gene_reaction_rule": "YBR298C or YDL247W or YJR160C or YGR289C"}, {"subsystem": "Transport, Extracellular", "name": "L malate reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MALt2r"]}, "metabolites": {"mal__L_c": 1.0, "h_e": -1.0, "mal__L_e": -1.0, "h_c": 1.0}, "id": "MALt2r", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Malate transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MALtm"]}, "metabolites": {"mal__L_c": -1.0, "pi_c": 1.0, "mal__L_m": 1.0, "pi_m": -1.0}, "id": "MALtm", "gene_reaction_rule": "YLR348C"}, {"subsystem": "Fructose and Mannose Metabolism", "name": "Mannose 1 phosphate guanylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MAN1PT"]}, "metabolites": {"man1p_c": -1.0, "ppi_c": 1.0, "gtp_c": -1.0, "h_c": -1.0, "gdpmann_c": 1.0}, "id": "MAN1PT", "gene_reaction_rule": "YDL055C"}, {"subsystem": "Fructose and Mannose Metabolism", "name": "Mannose-6-phosphate isomerase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MAN6PI"]}, "metabolites": {"man6p_c": -1.0, "f6p_c": 1.0}, "id": "MAN6PI", "gene_reaction_rule": "YER003C"}, {"subsystem": "Transport, Endoplasmic Reticular", "name": "Mannan endoplasmic reticulum transport via diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MANNANter"]}, "metabolites": {"mannan_r": 1.0, "mannan_c": -1.0}, "id": "MANNANter", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "D mannose transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MANt2"]}, "metabolites": {"man_e": -1.0, "h_e": -1.0, "h_c": 1.0, "man_c": 1.0}, "id": "MANt2", "gene_reaction_rule": "YJR158W or YHR096C or YOL156W or YNR072W or YDR345C or YDR343C or YFL011W or YJL219W or YJL214W or YMR011W or YHR094C or YEL069C or YDR342C or YHR092C or YDL245C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "2 methylcitrate dehydratase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MCITDm"]}, "metabolites": {"b124tc_m": 1.0, "h2o_m": 1.0, "hcit_m": -1.0}, "id": "MCITDm", "gene_reaction_rule": ""}, {"subsystem": "Anaplerotic reactions", "name": "MCITLm", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MCITLm"]}, "metabolites": {"pyr_m": 1.0, "succ_m": 1.0, "2mcit_m": -1.0}, "id": "MCITLm", "gene_reaction_rule": "YPR006C"}, {"subsystem": "Anaplerotic reactions", "name": "2-methylcitrate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MCITS"]}, "metabolites": {"h2o_c": -1.0, "oaa_c": -1.0, "2mcit_c": 1.0, "coa_c": 1.0, "h_c": 1.0, "ppcoa_c": -1.0}, "id": "MCITS", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Malonyl-CoA-ACP transacylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MCOATA"]}, "metabolites": {"malACP_c": 1.0, "malcoa_c": -1.0, "coa_c": 1.0, "ACP_c": -1.0}, "id": "MCOATA", "gene_reaction_rule": "YKL182W and YPL231W"}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Malonyl CoA ACP transacylase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MCOATAm"]}, "metabolites": {"malcoa_m": -1.0, "coa_m": 1.0, "malACP_m": 1.0, "ACP_m": -1.0}, "id": "MCOATAm", "gene_reaction_rule": "YOR221C"}, {"subsystem": "Oxidative Phosphorylation", "name": "Malate dehydrogenase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MDH"]}, "metabolites": {"nad_c": -1.0, "nadh_c": 1.0, "h_c": 1.0, "oaa_c": 1.0, "mal__L_c": -1.0}, "id": "MDH", "gene_reaction_rule": "YOL126C"}, {"subsystem": "Oxidative Phosphorylation", "name": "Malate dehydrogenase mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MDHm"]}, "metabolites": {"nad_m": -1.0, "oaa_m": 1.0, "h_m": 1.0, "mal__L_m": -1.0, "nadh_m": 1.0}, "id": "MDHm", "gene_reaction_rule": "YKL085W"}, {"subsystem": "Oxidative Phosphorylation", "name": "Malate dehydrogenase peroxisomal", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MDHp"]}, "metabolites": {"nadh_x": 1.0, "mal__L_x": -1.0, "nad_x": -1.0, "h_x": 1.0, "oaa_x": 1.0}, "id": "MDHp", "gene_reaction_rule": "YDL078C"}, {"subsystem": "Anaplerotic reactions", "name": "Malic enzyme NAD mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ME1m"]}, "metabolites": {"nad_m": -1.0, "pyr_m": 1.0, "mal__L_m": -1.0, "co2_m": 1.0, "nadh_m": 1.0}, "id": "ME1m", "gene_reaction_rule": "YKL029C"}, {"subsystem": "Anaplerotic reactions", "name": "Malic enzyme NADP mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ME2m"]}, "metabolites": {"pyr_m": 1.0, "nadph_m": 1.0, "mal__L_m": -1.0, "co2_m": 1.0, "nadp_m": -1.0}, "id": "ME2m", "gene_reaction_rule": "YKL029C"}, {"subsystem": "Transport, Extracellular", "name": "Melibiose transport in via symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MELIBt2"]}, "metabolites": {"melib_c": 1.0, "h_e": -1.0, "melib_e": -1.0, "h_c": 1.0}, "id": "MELIBt2", "gene_reaction_rule": ""}, {"subsystem": "Galactose metabolism", "name": "Melibiitol galactohydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MELTGH"]}, "metabolites": {"h2o_c": -1.0, "gal_c": 1.0, "melt_c": -1.0, "sbt__D_c": 1.0}, "id": "MELTGH", "gene_reaction_rule": "YBR184W"}, {"subsystem": "Methionine Metabolism", "name": "Methionine adenosyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["METAT"]}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "met__L_c": -1.0, "amet_c": 1.0, "pi_c": 1.0}, "id": "METAT", "gene_reaction_rule": "YLR180W or YDR502C"}, {"subsystem": "Methionine Metabolism", "name": "Metb1", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["METB1"]}, "metabolites": {"cys__L_c": -1.0, "ac_c": 1.0, "h_c": 1.0, "cyst__L_c": 1.0, "achms_c": -1.0}, "id": "METB1", "gene_reaction_rule": "YJR130C"}, {"subsystem": "Methionine Metabolism", "name": "METS", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["METS"]}, "metabolites": {"hcys__L_c": -1.0, "thf_c": 1.0, "met__L_c": 1.0, "5mthf_c": -1.0}, "id": "METS_1", "gene_reaction_rule": "YER091C"}, {"subsystem": "Methionine Metabolism", "name": "Methionyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["METTRS"]}, "metabolites": {"mettrna_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "met__L_c": -1.0, "trnamet_c": -1.0}, "id": "METTRS", "gene_reaction_rule": "YGR264C"}, {"subsystem": "Methionine Metabolism", "name": "Methionyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["METTRSm"]}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "mettrna_m": 1.0, "trnamet_m": -1.0, "met__L_m": -1.0, "amp_m": 1.0}, "id": "METTRSm", "gene_reaction_rule": "YGR171C"}, {"subsystem": "Transport, Mitochondrial", "name": "Methionine mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["METt2m"]}, "metabolites": {"met__L_m": -1.0, "h_m": -1.0, "h_c": 1.0, "met__L_c": 1.0}, "id": "METt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L methionine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["METt2r"]}, "metabolites": {"met__L_e": -1.0, "h_e": -1.0, "h_c": 1.0, "met__L_c": 1.0}, "id": "METt2r", "gene_reaction_rule": "YDR046C or YKR039W or YCL025C or YGR055W or YHL036W or YBR068C or YDR508C"}, {"subsystem": "Sterol Biosynthesis", "name": "Mevalonate kinase atp ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MEVK1"]}, "metabolites": {"5pmev_c": 1.0, "mev__R_c": -1.0, "h_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "MEVK1", "gene_reaction_rule": "YMR208W"}, {"subsystem": "Sterol Biosynthesis", "name": "Mevalonate kinase ctp ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MEVK2"]}, "metabolites": {"5pmev_c": 1.0, "cdp_c": 1.0, "mev__R_c": -1.0, "h_c": 1.0, "ctp_c": -1.0}, "id": "MEVK2", "gene_reaction_rule": "YMR208W"}, {"subsystem": "Sterol Biosynthesis", "name": "Mevalonate kinase gtp ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MEVK3"]}, "metabolites": {"5pmev_c": 1.0, "gtp_c": -1.0, "mev__R_c": -1.0, "gdp_c": 1.0, "h_c": 1.0}, "id": "MEVK3", "gene_reaction_rule": "YMR208W"}, {"subsystem": "Sterol Biosynthesis", "name": "Mevalonate kinase utp ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MEVK4"]}, "metabolites": {"5pmev_c": 1.0, "mev__R_c": -1.0, "utp_c": -1.0, "udp_c": 1.0, "h_c": 1.0}, "id": "MEVK4", "gene_reaction_rule": "YMR208W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Methylene fatty acyl phospholipid synthase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MFAPS_SC"]}, "metabolites": {"ptdmeeta_SC_c": -0.01, "amet_c": -1.0, "ahcys_c": 1.0, "ptd2meeta_SC_c": 0.01, "h_c": 1.0}, "id": "MFAPS_SC", "gene_reaction_rule": "YJR073C"}, {"subsystem": "Methionine Metabolism", "name": "5 methyltetrahydropteroyltriglutamate homocysteine S methyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MHPGLUT"]}, "metabolites": {"hcys__L_c": -1.0, "hpglu_c": 1.0, "met__L_c": 1.0, "mhpglu_c": -1.0}, "id": "MHPGLUT", "gene_reaction_rule": "YER091C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Myo-inositol 1-phosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MI1PP"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "inost_c": 1.0, "mi1p__D_c": -1.0}, "id": "MI1PP", "gene_reaction_rule": "YHR046C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Myo Inositol 1 phosphate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MI1PS"]}, "metabolites": {"g6p_c": -1.0, "mi1p__D_c": 1.0}, "id": "MI1PS", "gene_reaction_rule": "YJL153C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol P 2 ceramide synthase ceramide 1 24C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIP2CS124_SC"]}, "metabolites": {"mip2c124_SC_c": 0.01, "12dgr_SC_c": 0.01, "ptd1ino_SC_c": -0.01, "mipc124_SC_c": -0.01}, "id": "MIP2CS124_SC", "gene_reaction_rule": "YDR072C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol P 2 ceramide synthase ceramide 1 26C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIP2CS126_SC"]}, "metabolites": {"12dgr_SC_c": 0.01, "ptd1ino_SC_c": -0.01, "mip2c126_SC_c": 0.01, "mipc126_SC_c": -0.01}, "id": "MIP2CS126_SC", "gene_reaction_rule": "YDR072C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol P 2 ceramide synthase ceramide 2 26C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIP2CS224_SC"]}, "metabolites": {"mip2c224_SC_c": 0.01, "mipc224_SC_c": -0.01, "ptd1ino_SC_c": -0.01, "12dgr_SC_c": 0.01}, "id": "MIP2CS224_SC", "gene_reaction_rule": "YDR072C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol P 2 ceramide synthase ceramide 2 24C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIP2CS226_SC"]}, "metabolites": {"mipc226_SC_c": -0.01, "12dgr_SC_c": 0.01, "mip2c226_SC_c": 0.01, "ptd1ino_SC_c": -0.01}, "id": "MIP2CS226_SC", "gene_reaction_rule": "YDR072C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol P 2 ceramide synthase ceramide 3 24C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIP2CS324_SC"]}, "metabolites": {"mipc324_SC_c": -0.01, "ptd1ino_SC_c": -0.01, "mip2c324_SC_c": 0.01, "12dgr_SC_c": 0.01}, "id": "MIP2CS324_SC", "gene_reaction_rule": "YDR072C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol P 2 ceramide synthase ceramide 3 26C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIP2CS326_SC"]}, "metabolites": {"mip2c326_SC_c": 0.01, "12dgr_SC_c": 0.01, "ptd1ino_SC_c": -0.01, "mipc326_SC_c": -0.01}, "id": "MIP2CS326_SC", "gene_reaction_rule": "YDR072C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositiol phophorylceramide synthase ceramide 1 24C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIPCS124_SC"]}, "metabolites": {"gdpmann_c": -1.0, "ipc124_SC_c": -0.01, "gdp_c": 1.0, "h_c": 1.0, "mipc124_SC_c": 0.01}, "id": "MIPCS124_SC", "gene_reaction_rule": "YBR036C or YPL057C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol phosphorylceramide synthase ceramide 1 26C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIPCS126_SC"]}, "metabolites": {"mipc126_SC_c": 0.01, "gdpmann_c": -1.0, "gdp_c": 1.0, "h_c": 1.0, "ipc126_SC_c": -0.01}, "id": "MIPCS126_SC", "gene_reaction_rule": "YPL057C or YBR036C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol phosphorylceramide synthase ceramide 2 24C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIPCS224_SC"]}, "metabolites": {"mipc224_SC_c": 0.01, "gdpmann_c": -1.0, "gdp_c": 1.0, "h_c": 1.0, "ipc224_SC_c": -0.01}, "id": "MIPCS224_SC", "gene_reaction_rule": "YBR036C or YPL057C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol phosphorylceramide synthase ceramide 2 26C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIPCS226_SC"]}, "metabolites": {"ipc226_SC_c": -0.01, "mipc226_SC_c": 0.01, "gdpmann_c": -1.0, "gdp_c": 1.0, "h_c": 1.0}, "id": "MIPCS226_SC", "gene_reaction_rule": "YPL057C or YBR036C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol phosphorylceramide synthase ceramide 3 24C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIPCS324_SC"]}, "metabolites": {"mipc324_SC_c": 0.01, "gdpmann_c": -1.0, "gdp_c": 1.0, "h_c": 1.0, "ipc324_SC_c": -0.01}, "id": "MIPCS324_SC", "gene_reaction_rule": "YBR036C or YPL057C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Mannose inositol phosphorylceramide synthase ceramide 3 26C yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MIPCS326_SC"]}, "metabolites": {"gdpmann_c": -1.0, "mipc326_SC_c": 0.01, "gdp_c": 1.0, "h_c": 1.0, "ipc326_SC_c": -0.01}, "id": "MIPCS326_SC", "gene_reaction_rule": "YBR036C or YPL057C"}, {"subsystem": "Transport, Mitochondrial", "name": "MLTHFtm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MLTHFtm"]}, "metabolites": {"mlthf_m": 1.0, "mlthf_c": -1.0}, "id": "MLTHFtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "S methylmethionine permease", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MMETt2"]}, "metabolites": {"mmet_e": -1.0, "h_e": -1.0, "h_c": 1.0, "mmet_c": 1.0}, "id": "MMETt2", "gene_reaction_rule": "YLL061W"}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "3-methyl-2-oxobutanoate hydroxymethyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MOHMT"]}, "metabolites": {"mlthf_c": -1.0, "h2o_c": -1.0, "thf_c": 1.0, "2dhp_c": 1.0, "3mob_c": -1.0}, "id": "MOHMT", "gene_reaction_rule": "YBR176W"}, {"subsystem": "Folate Metabolism", "name": "MTHFC", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MTHFC"]}, "metabolites": {"h2o_c": -1.0, "10fthf_c": 1.0, "methf_c": -1.0}, "id": "MTHFC_1", "gene_reaction_rule": "YGR204W"}, {"subsystem": "Folate Metabolism", "name": "MTHFCm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MTHFCm"]}, "metabolites": {"10fthf_m": 1.0, "h2o_m": -1.0, "methf_m": -1.0}, "id": "MTHFCm_1", "gene_reaction_rule": "YBR084W"}, {"subsystem": "Folate Metabolism", "name": "MTHFD", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MTHFD"]}, "metabolites": {"nadp_c": -1.0, "nadph_c": 1.0, "h_c": 1.0, "mlthf_c": -1.0, "methf_c": 1.0}, "id": "MTHFD_1", "gene_reaction_rule": "YGR204W"}, {"subsystem": "Folate Metabolism", "name": "MTHFD2", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MTHFD2"]}, "metabolites": {"mlthf_c": -1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "methf_c": 1.0}, "id": "MTHFD2", "gene_reaction_rule": "YKR080W"}, {"subsystem": "Folate Metabolism", "name": "MTHFDm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["MTHFDm"]}, "metabolites": {"mlthf_m": -1.0, "nadph_m": 1.0, "methf_m": 1.0, "h_m": 1.0, "nadp_m": -1.0}, "id": "MTHFDm_1", "gene_reaction_rule": "YBR084W"}, {"subsystem": "Folate Metabolism", "name": "MTHFR3", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["MTHFR3"]}, "metabolites": {"nadp_c": 1.0, "nadph_c": -1.0, "5mthf_c": 1.0, "mlthf_c": -1.0, "h_c": -1.0}, "id": "MTHFR3_1", "gene_reaction_rule": "YPL023C or YGL125W"}, {"subsystem": "Other Amino Acid Metabolism", "name": "N4 AcetylaminobutanalNAD oxidoreductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NABTNO"]}, "metabolites": {"h2o_c": -1.0, "n4abutn_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "nadh_c": 1.0, "4aabutn_c": 1.0}, "id": "NABTNO", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "NAD diphosphatase peroxisomal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADDPp"]}, "metabolites": {"amp_x": 1.0, "h2o_x": -1.0, "nad_x": -1.0, "h_x": 2.0, "nmn_x": 1.0}, "id": "NADDPp", "gene_reaction_rule": "YGL067W"}, {"subsystem": "Oxidative Phosphorylation", "name": "NADH dehydrogenase cytosolicmitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADH2_u6cm"]}, "metabolites": {"q6_m": -1.0, "nadh_c": -1.0, "q6h2_m": 1.0, "nad_c": 1.0, "h_c": -1.0}, "id": "NADH2_u6cm", "gene_reaction_rule": "YMR145C or YDL085W"}, {"subsystem": "Oxidative Phosphorylation", "name": "NADH dehydrogenase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADH2_u6m"]}, "metabolites": {"nad_m": 1.0, "q6_m": -1.0, "h_m": -1.0, "q6h2_m": 1.0, "nadh_m": -1.0}, "id": "NADH2_u6m", "gene_reaction_rule": "YML120C or YKL192C"}, {"subsystem": "NAD Biosynthesis", "name": "NAD kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADK"]}, "metabolites": {"nad_c": -1.0, "nadp_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "NADK", "gene_reaction_rule": "YJR049C or YEL041W or YPL188W"}, {"subsystem": "NAD Biosynthesis", "name": "NAD kinase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADKm"]}, "metabolites": {"adp_m": 1.0, "nad_m": -1.0, "atp_m": -1.0, "h_m": 1.0, "nadp_m": 1.0}, "id": "NADKm", "gene_reaction_rule": "YEL041W or YPL188W or YJR049C"}, {"subsystem": "NAD Biosynthesis", "name": "NAD nucleosidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADN"]}, "metabolites": {"h2o_c": -1.0, "nad_c": -1.0, "h_c": 1.0, "adprib_c": 1.0, "ncam_c": 1.0}, "id": "NADN", "gene_reaction_rule": ""}, {"subsystem": "NAD Biosynthesis", "name": "NAD nucleosidase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADNm"]}, "metabolites": {"adprib_m": 1.0, "ncam_m": 1.0, "h_m": 1.0, "h2o_m": -1.0, "nad_m": -1.0}, "id": "NADNm", "gene_reaction_rule": ""}, {"subsystem": "NAD Biosynthesis", "name": "NADP phosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADPPPS"]}, "metabolites": {"h2o_c": -1.0, "nadp_c": -1.0, "pi_c": 1.0, "nad_c": 1.0}, "id": "NADPPPS", "gene_reaction_rule": ""}, {"subsystem": "NAD Biosynthesis", "name": "NADP phosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADPPPSm"]}, "metabolites": {"nad_m": 1.0, "h2o_m": -1.0, "nadp_m": -1.0, "pi_m": 1.0}, "id": "NADPPPSm", "gene_reaction_rule": ""}, {"subsystem": "NAD Biosynthesis", "name": "NAD synthase (nh3)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADS1"]}, "metabolites": {"dnad_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "h_c": 1.0, "nad_c": 1.0, "nh4_c": -1.0, "amp_c": 1.0}, "id": "NADS1", "gene_reaction_rule": "YHR074W"}, {"subsystem": "NAD Biosynthesis", "name": "NADS1m", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NADS1m"]}, "metabolites": {"h_m": 1.0, "ppi_m": 1.0, "atp_m": -1.0, "dnad_m": -1.0, "nh4_m": -1.0, "nad_m": 1.0, "amp_m": 1.0}, "id": "NADS1m", "gene_reaction_rule": "YHR074W"}, {"subsystem": "NAD Biosynthesis", "name": "NAPRTase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NAPRT"]}, "metabolites": {"nicrnt_c": 1.0, "ppi_c": 1.0, "nac_c": -1.0, "prpp_c": -1.0, "h_c": -1.0}, "id": "NAPRT", "gene_reaction_rule": "YOR209C"}, {"subsystem": "NAD Biosynthesis", "name": "NAPRTase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NAPRTm"]}, "metabolites": {"prpp_m": -1.0, "h_m": -1.0, "ppi_m": 1.0, "nac_m": -1.0, "nicrnt_m": 1.0}, "id": "NAPRTm", "gene_reaction_rule": "YOR209C"}, {"subsystem": "Transport, Extracellular", "name": "Sodium proton antiporter HNA is 11 ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NAt3_1"]}, "metabolites": {"na1_c": -1.0, "h_e": -1.0, "h_c": 1.0, "na1_e": 1.0}, "id": "NAt3_1", "gene_reaction_rule": "YLR138W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside diphosphatase GDP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NDP3"]}, "metabolites": {"h2o_c": -1.0, "gmp_c": 1.0, "gdp_c": -1.0, "h_c": 1.0, "pi_c": 1.0}, "id": "NDP3", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside diphosphatase GDP Golgi", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NDP3g"]}, "metabolites": {"gdp_g": -1.0, "h_g": 1.0, "gmp_g": 1.0, "h2o_g": -1.0, "pi_g": 1.0}, "id": "NDP3g", "gene_reaction_rule": "YEL042W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside diphosphatase dGDP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NDP4"]}, "metabolites": {"h2o_c": -1.0, "dgdp_c": -1.0, "dgmp_c": 1.0, "h_c": 1.0, "pi_c": 1.0}, "id": "NDP4", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside-diphosphate kinase (ATP:GDP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NDPK1"]}, "metabolites": {"gtp_c": 1.0, "gdp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "NDPK1", "gene_reaction_rule": "YKL067W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside-diphosphate kinase (ATP:UDP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NDPK2"]}, "metabolites": {"udp_c": -1.0, "utp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "NDPK2", "gene_reaction_rule": "YKL067W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside-diphosphate kinase (ATP:CDP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NDPK3"]}, "metabolites": {"ctp_c": 1.0, "cdp_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "NDPK3", "gene_reaction_rule": "YKL067W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside-diphosphate kinase (ATP:dTDP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NDPK4"]}, "metabolites": {"dtdp_c": -1.0, "dttp_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "NDPK4", "gene_reaction_rule": "YKL067W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside-diphosphate kinase (ATP:dGDP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NDPK5"]}, "metabolites": {"dgdp_c": -1.0, "dgtp_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "NDPK5", "gene_reaction_rule": "YKL067W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside-diphosphate kinase (ATP:dUDP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NDPK6"]}, "metabolites": {"adp_c": 1.0, "dudp_c": -1.0, "atp_c": -1.0, "dutp_c": 1.0}, "id": "NDPK6", "gene_reaction_rule": "YKL067W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside-diphosphate kinase (ATP:dCDP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NDPK7"]}, "metabolites": {"dctp_c": 1.0, "atp_c": -1.0, "adp_c": 1.0, "dcdp_c": -1.0}, "id": "NDPK7", "gene_reaction_rule": "YKL067W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside-diphosphate kinase (ATP:dADP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NDPK8"]}, "metabolites": {"dadp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "datp_c": 1.0}, "id": "NDPK8", "gene_reaction_rule": "YKL067W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside diphosphate kinase ATPIDP ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NDPK9"]}, "metabolites": {"itp_c": 1.0, "idp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "NDPK9", "gene_reaction_rule": "YKL067W"}, {"subsystem": "Transport, Extracellular", "name": "Ammonia reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NH4t"]}, "metabolites": {"nh4_e": -1.0, "nh4_c": 1.0}, "id": "NH4t", "gene_reaction_rule": "YNL142W or YPR138C or YGR121C"}, {"subsystem": "Transport, Mitochondrial", "name": "NH3 mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NH4tm"]}, "metabolites": {"nh4_m": 1.0, "nh4_c": -1.0}, "id": "NH4tm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Ammonia peroxisomal transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NH4tp"]}, "metabolites": {"nh4_c": -1.0, "nh4_x": 1.0}, "id": "NH4tp", "gene_reaction_rule": ""}, {"subsystem": "Fatty Acid Biosynthesis", "name": "Nicotinamide-nucleotide adenylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NMNAT"]}, "metabolites": {"ppi_c": 1.0, "nmn_c": -1.0, "nad_c": 1.0, "atp_c": -1.0, "h_c": -1.0}, "id": "NMNAT", "gene_reaction_rule": "YGR010W"}, {"subsystem": "NAD Biosynthesis", "name": "Nicotinamide nucleotide adenylyltransferase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NMNATm"]}, "metabolites": {"atp_m": -1.0, "nad_m": 1.0, "nmn_m": -1.0, "h_m": -1.0, "ppi_m": 1.0}, "id": "NMNATm", "gene_reaction_rule": "YLR328W"}, {"subsystem": "Transport, Extracellular", "name": "Nmntp", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NMNTP"]}, "metabolites": {"nmn_e": -1.0, "h_e": -1.0, "nmn_c": 1.0, "h_c": 1.0}, "id": "NMNTP", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "NMN mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NMNt2m"]}, "metabolites": {"nmn_m": 1.0, "h_m": 1.0, "nmn_c": -1.0, "h_c": -1.0}, "id": "NMNt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "NMN peroxisomal transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NMNt2p"]}, "metabolites": {"nmn_c": -1.0, "h_c": -1.0, "h_x": 1.0, "nmn_x": 1.0}, "id": "NMNt2p", "gene_reaction_rule": ""}, {"subsystem": "NAD Biosynthesis", "name": "Nicotinamidase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NNAMr"]}, "metabolites": {"h2o_c": -1.0, "ncam_c": -1.0, "nac_c": 1.0, "nh4_c": 1.0}, "id": "NNAM", "gene_reaction_rule": "YGL037C"}, {"subsystem": "NAD Biosynthesis", "name": "Nicotinamidase reversible mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["NNAMrm"]}, "metabolites": {"ncam_m": -1.0, "nh4_m": 1.0, "h2o_m": -1.0, "nac_m": 1.0}, "id": "NNAMrm", "gene_reaction_rule": "YGL037C"}, {"subsystem": "NAD Biosynthesis", "name": "Nicotinate-nucleotide adenylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NNAT"]}, "metabolites": {"nicrnt_c": -1.0, "dnad_c": 1.0, "ppi_c": 1.0, "h_c": -1.0, "atp_c": -1.0}, "id": "NNATr", "gene_reaction_rule": "YLR328W"}, {"subsystem": "NAD Biosynthesis", "name": "Nicotinate nucleotide adenylyltransferase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NNATm"]}, "metabolites": {"atp_m": -1.0, "h_m": -1.0, "ppi_m": 1.0, "nicrnt_m": -1.0, "dnad_m": 1.0}, "id": "NNATm", "gene_reaction_rule": "YLR328W"}, {"subsystem": "NAD Biosynthesis", "name": "Nicotinate-nucleotide diphosphorylase (carboxylating)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NNDPR"]}, "metabolites": {"nicrnt_c": 1.0, "ppi_c": 1.0, "quln_c": -1.0, "h_c": -2.0, "co2_c": 1.0, "prpp_c": -1.0}, "id": "NNDPR", "gene_reaction_rule": "YFR047C"}, {"subsystem": "NAD Biosynthesis", "name": "Nicotinate nucleotide diphosphorylase carboxylating mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NNDPRm"]}, "metabolites": {"quln_m": -1.0, "ppi_m": 1.0, "nicrnt_m": 1.0, "prpp_m": -1.0, "co2_m": 1.0, "h_m": -2.0}, "id": "NNDPRm", "gene_reaction_rule": "YFR047C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (dUMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD1"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "dump_c": -1.0, "duri_c": 1.0}, "id": "NTD1", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (XMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD10"]}, "metabolites": {"xmp_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "xtsn_c": 1.0}, "id": "NTD10", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (IMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD11"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "imp_c": -1.0, "ins_c": 1.0}, "id": "NTD11", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (UMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD2"]}, "metabolites": {"ump_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "uri_c": 1.0}, "id": "NTD2", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (dCMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD3"]}, "metabolites": {"dcmp_c": -1.0, "dcyt_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0}, "id": "NTD3", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (CMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD4"]}, "metabolites": {"cytd_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "cmp_c": -1.0}, "id": "NTD4", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (dTMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD5"]}, "metabolites": {"dtmp_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "thymd_c": 1.0}, "id": "NTD5", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (dAMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD6"]}, "metabolites": {"dad_2_c": 1.0, "damp_c": -1.0, "pi_c": 1.0, "h2o_c": -1.0}, "id": "NTD6", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (AMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD7"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "adn_c": 1.0, "amp_c": -1.0}, "id": "NTD7", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (dGMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD8"]}, "metabolites": {"dgsn_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "dgmp_c": -1.0}, "id": "NTD8", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "5'-nucleotidase (GMP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD9"]}, "metabolites": {"h2o_c": -1.0, "gmp_c": -1.0, "pi_c": 1.0, "gsn_c": 1.0}, "id": "NTD9", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside-triphosphatase (GTP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTP3"]}, "metabolites": {"gdp_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "gtp_c": -1.0, "h_c": 1.0}, "id": "NTP3", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Nucleoside triphosphatase dGTP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTP4"]}, "metabolites": {"dgdp_c": 1.0, "pi_c": 1.0, "dgtp_c": -1.0, "h2o_c": -1.0, "h_c": 1.0}, "id": "NTP4", "gene_reaction_rule": ""}, {"subsystem": "Nitrogen Metabolism", "name": "Nitrilase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTRLASE"]}, "metabolites": {"ind3ac_c": 1.0, "h2o_c": -2.0, "ind3acnl_c": -1.0, "nh4_c": 1.0}, "id": "NTRLASE", "gene_reaction_rule": "YLR351C or YJL126W"}, {"subsystem": "Other Amino Acid Metabolism", "name": "Nitrilase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTRLASE2"]}, "metabolites": {"h2o_c": -2.0, "ala__L_c": 1.0, "nh4_c": 1.0, "aprop_c": -1.0}, "id": "NTRLASE2", "gene_reaction_rule": "YJL126W or YLR351C"}, {"subsystem": "Other Amino Acid Metabolism", "name": "Nitrilase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTRLASE3"]}, "metabolites": {"glu__L_c": 1.0, "acybut_c": -1.0, "nh4_c": 1.0, "h2o_c": -2.0}, "id": "NTRLASE3", "gene_reaction_rule": "YLR351C or YJL126W"}, {"subsystem": "Transport, Extracellular", "name": "O2 transport diffusion ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["O2t"]}, "metabolites": {"o2_c": 1.0, "o2_e": -1.0}, "id": "O2t", "gene_reaction_rule": ""}, {"subsystem": "Transport, Endoplasmic Reticular", "name": "O2 transport endoplasmic reticulum", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["O2ter"]}, "metabolites": {"o2_r": 1.0, "o2_c": -1.0}, "id": "O2ter", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "O2 transport diffusion ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["O2tm"]}, "metabolites": {"o2_c": -1.0, "o2_m": 1.0}, "id": "O2tm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Oxaloacetate transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["OAAt2m"]}, "metabolites": {"oaa_m": 1.0, "h_m": 1.0, "h_c": -1.0, "oaa_c": -1.0}, "id": "OAAt2m", "gene_reaction_rule": "YKL120W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Ornithine carbamoyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OCBTi"]}, "metabolites": {"cbp_c": -1.0, "citr__L_c": 1.0, "orn_c": -1.0, "h_c": 1.0, "pi_c": 1.0}, "id": "OCBT", "gene_reaction_rule": "YJL088W"}, {"subsystem": "Transport, Extracellular", "name": "Octadecanoate n C180 transport in via uniport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OCDCAt"]}, "metabolites": {"ocdca_e": -1.0, "ocdca_c": 1.0}, "id": "OCDCAt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Octadecenoate n C181 transport in via uniport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OCDCEAt"]}, "metabolites": {"ocdcea_c": 1.0, "ocdcea_e": -1.0}, "id": "OCDCEAt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Octadecynoate n C182 transport in via uniport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OCDCYAt"]}, "metabolites": {"ocdcya_e": -1.0, "ocdcya_c": 1.0}, "id": "OCDCYAt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "OCTDP 5tm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["OCTDP_5tm"]}, "metabolites": {"octdp_5_m": 1.0, "octdp_5_c": -1.0}, "id": "OCTDP_5tm", "gene_reaction_rule": ""}, {"subsystem": "Pyridoxine Metabolism", "name": "O-Phospho-4-hydroxy-L-threonine:2-oxoglutarate aminotransferase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["OHPBAT"]}, "metabolites": {"akg_c": 1.0, "phthr_c": 1.0, "glu__L_c": -1.0, "ohpb_c": -1.0}, "id": "OHPBAT", "gene_reaction_rule": "YOR184W"}, {"subsystem": "Quinone Biosynthesis", "name": "OHPHM6n", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OHPHM6n"]}, "metabolites": {"h_n": 1.0, "amet_n": -1.0, "2omph_5_n": 1.0, "ahcys_n": 1.0, "2ohph_5_n": -1.0}, "id": "OHPHM6n", "gene_reaction_rule": "YPL266W"}, {"subsystem": "Quinone Biosynthesis", "name": "OMBZLM6m", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OMBZLM6m"]}, "metabolites": {"2ombzl_5_m": -1.0, "2ommbl_5_m": 1.0, "h_m": 1.0, "ahcys_m": 1.0, "amet_m": -1.0}, "id": "OMBZLM6m", "gene_reaction_rule": "YML110C"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "2-Oxo-4-methyl-3-carboxypentanoate decarboxylation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OMCDC"]}, "metabolites": {"3c4mop_c": -1.0, "co2_c": 1.0, "4mop_c": 1.0, "h_c": -1.0}, "id": "OMCDC", "gene_reaction_rule": "YJR148W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "2 oxo 4 methyl 3 carboxypentanoate decarboxylation", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OMCDCm"]}, "metabolites": {"4mop_m": 1.0, "h_m": -1.0, "co2_m": 1.0, "3c4mop_m": -1.0}, "id": "OMCDCm", "gene_reaction_rule": "YHR208W"}, {"subsystem": "Quinone Biosynthesis", "name": "OMMBLHX6m", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OMMBLHX6m"]}, "metabolites": {"2ommbl_5_m": -1.0, "2omhmbl_5_m": 1.0, "o2_m": -0.5}, "id": "OMMBLHX6m", "gene_reaction_rule": "YGR255C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Orotidine-5'-phosphate decarboxylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OMPDC"]}, "metabolites": {"ump_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "orot5p_c": -1.0}, "id": "OMPDC", "gene_reaction_rule": "YEL021W"}, {"subsystem": "Quinone Biosynthesis", "name": "OMPHHX6m", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OMPHHX6m"]}, "metabolites": {"2ombzl_5_m": 1.0, "2omph_5_m": -1.0, "o2_m": -0.5}, "id": "OMPHHX6m", "gene_reaction_rule": ""}, {"subsystem": "Quinone Biosynthesis", "name": "OPHBDC6", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OPHBDC6"]}, "metabolites": {"2oph_5_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "3ophb_5_c": -1.0}, "id": "OPHBDC6", "gene_reaction_rule": "YDR538W"}, {"subsystem": "Quinone Biosynthesis", "name": "OPHHX6", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OPHHX6"]}, "metabolites": {"o2_c": -0.5, "2ohph_5_c": 1.0, "2oph_5_c": -1.0}, "id": "OPHHX6", "gene_reaction_rule": ""}, {"subsystem": "Arginine and Proline Metabolism", "name": "Ornithine Decarboxylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ORNDC"]}, "metabolites": {"ptrc_c": 1.0, "co2_c": 1.0, "orn_c": -1.0, "h_c": -1.0}, "id": "ORNDC", "gene_reaction_rule": "YKL184W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Ornithine transaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ORNTA"]}, "metabolites": {"akg_c": -1.0, "glu5sa_c": 1.0, "glu__L_c": 1.0, "orn_c": -1.0}, "id": "ORNTA", "gene_reaction_rule": "YLR438W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Ornithine transacetylase irreversible mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ORNTACim"]}, "metabolites": {"acorn_m": -1.0, "orn_m": 1.0, "glu__L_m": -1.0, "acglu_m": 1.0}, "id": "ORNTACim", "gene_reaction_rule": "YMR062C"}, {"subsystem": "Transport, Extracellular", "name": "Orntithine reversible transport in via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ORNt2r"]}, "metabolites": {"orn_e": -1.0, "h_e": -1.0, "orn_c": 1.0, "h_c": 1.0}, "id": "ORNt2r", "gene_reaction_rule": "YKR039W or YEL063C"}, {"subsystem": "Transport, Mitochondrial", "name": "Ornithine mitochondrial transport via proton antiport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ORNt3m"]}, "metabolites": {"orn_m": -1.0, "h_m": 1.0, "orn_c": 1.0, "h_c": -1.0}, "id": "ORNt3m", "gene_reaction_rule": "YOR130C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Orotate phosphoribosyltransferase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ORPT"]}, "metabolites": {"ppi_c": -1.0, "orot_c": 1.0, "prpp_c": 1.0, "orot5p_c": -1.0}, "id": "ORPT", "gene_reaction_rule": "YML106W or YMR271C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "Non enzymatic reaction", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["OXAGm"]}, "metabolites": {"2oxoadp_m": 1.0, "oxag_m": -1.0, "h_m": -1.0, "co2_m": 1.0}, "id": "OXAGm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "2 oxodicarboylate transporter mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["OXO2Ctm"]}, "metabolites": {"akg_c": 1.0, "oxag_m": 1.0, "oxag_c": -1.0, "akg_m": -1.0}, "id": "OXO2Ctm", "gene_reaction_rule": "YPL134C or YOR222W"}, {"subsystem": "Glutamate metabolism", "name": "1 pyrroline 5 carboxylate dehydrogenase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["P5CDm"]}, "metabolites": {"glu__L_m": 1.0, "h2o_m": -2.0, "nadh_m": 1.0, "1pyr5c_m": -1.0, "nad_m": -1.0, "h_m": 1.0}, "id": "P5CDm", "gene_reaction_rule": ""}, {"subsystem": "Arginine and Proline Metabolism", "name": "Pyrroline-5-carboxylate reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["P5CR"]}, "metabolites": {"1pyr5c_c": -1.0, "pro__L_c": 1.0, "nadph_c": -1.0, "h_c": -2.0, "nadp_c": 1.0}, "id": "P5CR", "gene_reaction_rule": "YER023W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidate kinase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PAK_SC"]}, "metabolites": {"pa_SC_c": -0.01, "dagpy_SC_c": 0.01, "adp_c": 1.0, "atp_c": -1.0}, "id": "PAK_SC", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Panthetheine 4 phosphate reversible mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PAN4Ptm"]}, "metabolites": {"pan4p_c": -1.0, "pan4p_m": 1.0}, "id": "PAN4Ptm", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Pantothenate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PANTS"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "pnto__R_c": 1.0, "amp_c": 1.0, "ala_B_c": -1.0, "pant__R_c": -1.0, "h_c": 1.0}, "id": "PANTS", "gene_reaction_rule": "YIL145C"}, {"subsystem": "Transport, Mitochondrial", "name": "Pantothenate mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PANTtm"]}, "metabolites": {"pant__R_c": -1.0, "pant__R_m": 1.0}, "id": "PANTtm", "gene_reaction_rule": ""}, {"subsystem": "Cysteine Metabolism", "name": "Phosphoadenylyl-sulfate reductase (thioredoxin)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PAPSR"]}, "metabolites": {"so3_c": 1.0, "pap_c": 1.0, "trdox_c": 1.0, "h_c": 2.0, "paps_c": -1.0, "trdrd_c": -1.0}, "id": "PAPSR", "gene_reaction_rule": "YPR167C"}, {"subsystem": "Transport, Extracellular", "name": "PAP reversible uniport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PAPt"]}, "metabolites": {"pap_e": -1.0, "pap_c": 1.0}, "id": "PAPt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Adenosine 3 5 bisphosphate mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PAPtm"]}, "metabolites": {"pap_m": 1.0, "pap_c": -1.0}, "id": "PAPtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Phosphatidate reversible transport mitochondrial yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PAtm_SC"]}, "metabolites": {"pa_SC_c": -1.0, "pa_SC_m": 1.0}, "id": "PAtm_SC", "gene_reaction_rule": ""}, {"subsystem": "Anaplerotic reactions", "name": "Pyruvate carboxylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PC"]}, "metabolites": {"oaa_c": 1.0, "atp_c": -1.0, "hco3_c": -1.0, "pyr_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "PC", "gene_reaction_rule": "YGL062W or YBR218C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "PCLAD", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PCLAD"]}, "metabolites": {"cmusa_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "am6sa_c": 1.0}, "id": "PCLAD", "gene_reaction_rule": ""}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "3',5'-cyclic-nucleotide phosphodiesterase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PDE1"]}, "metabolites": {"h2o_c": -1.0, "camp_c": -1.0, "h_c": 1.0, "amp_c": 1.0}, "id": "PDE1", "gene_reaction_rule": "YOR360C or YGL248W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "3 5 cyclic nucleotide phosphodiesterase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PDE2"]}, "metabolites": {"h2o_c": -1.0, "damp_c": 1.0, "h_c": 1.0, "35cdamp_c": -1.0}, "id": "PDE2", "gene_reaction_rule": "YOR360C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "3 5 cyclic nucleotide phosphodiesterase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PDE3"]}, "metabolites": {"35cimp_c": -1.0, "h2o_c": -1.0, "h_c": 1.0, "imp_c": 1.0}, "id": "PDE3", "gene_reaction_rule": "YOR360C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "3',5'-cyclic-nucleotide phosphodiesterase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PDE4"]}, "metabolites": {"h2o_c": -1.0, "gmp_c": 1.0, "h_c": 1.0, "35cgmp_c": -1.0}, "id": "PDE4", "gene_reaction_rule": "YOR360C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "3 5 cyclic nucleotide phosphodiesterase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PDE5"]}, "metabolites": {"h2o_c": -1.0, "35ccmp_c": -1.0, "h_c": 1.0, "cmp_c": 1.0}, "id": "PDE5", "gene_reaction_rule": "YOR360C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Glycine cleavage complex lipoamide mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GCC2cm", "PDHcm"]}, "metabolites": {"lpam_m": 1.0, "nad_m": -1.0, "h_m": 1.0, "nadh_m": 1.0, "dhlam_m": -1.0}, "id": "GCC2cm_copy2", "gene_reaction_rule": "YIL125W and YFL018C and YDR148C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Pyruvate dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PDHm"]}, "metabolites": {"pyr_m": -1.0, "accoa_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "co2_m": 1.0}, "id": "PDHm", "gene_reaction_rule": "YNL071W and YFL018C and (YBR221C and YER178W)"}, {"subsystem": "Pyridoxine Metabolism", "name": "Pyridoxine 5'-phosphate oxidase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PDX5PO"]}, "metabolites": {"o2_c": -1.0, "pydx5p_c": 1.0, "pdx5p_c": -1.0, "h2o2_c": 1.0}, "id": "PDX5POi", "gene_reaction_rule": "YBR035C"}, {"subsystem": "Other Amino Acid Metabolism", "name": "Peptide alpha N acetyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PEPAT"]}, "metabolites": {"pepd_c": -1.0, "coa_c": 1.0, "apep_c": 1.0, "h_c": 1.0, "accoa_c": -1.0}, "id": "PEPAT", "gene_reaction_rule": "YDL040C or YGR147C"}, {"subsystem": "Transport, Extracellular", "name": "Peptide transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PEPDt3"]}, "metabolites": {"pepd_c": 1.0, "h_e": -1.0, "h_c": 1.0, "pepd_e": -1.0}, "id": "PEPDt3", "gene_reaction_rule": "YKR093W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphoethanolamine cytidyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PETHCT"]}, "metabolites": {"cdpea_c": 1.0, "ctp_c": -1.0, "ppi_c": 1.0, "h_c": -1.0, "ethamp_c": -1.0}, "id": "PETHCT", "gene_reaction_rule": "YGR007W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylethanolamine N methyltransferase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PETOHM_SC"]}, "metabolites": {"ptdmeeta_SC_c": 0.01, "amet_c": -1.0, "ahcys_c": 1.0, "h_c": 1.0, "pe_SC_c": -0.01}, "id": "PETOHM_SC", "gene_reaction_rule": "YGR157W"}, {"subsystem": "Transport, Golgi Apparatus", "name": "Phosphatidylethanolamine Golgi transport yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PEtg_SC"]}, "metabolites": {"pe_SC_g": 1.0, "pe_SC_c": -1.0}, "id": "PEtg_SC", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Phosphatidylethanolamine mitochondrial transport yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PEtm_SC"]}, "metabolites": {"pe_SC_m": 1.0, "pe_SC_c": -1.0}, "id": "PEtm_SC", "gene_reaction_rule": ""}, {"subsystem": "Transport, Vacuolar", "name": "Phosphatidylethanolamine vacuolar transport yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PEtv_SC"]}, "metabolites": {"pe_SC_v": 1.0, "pe_SC_c": -1.0}, "id": "PEtv_SC", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Phosphofructokinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PFK"]}, "metabolites": {"f6p_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "fdp_c": 1.0}, "id": "PFK", "gene_reaction_rule": "YMR205C and YGR240C"}, {"subsystem": "Fructose and Mannose Metabolism", "name": "6 phosphofructo 2 kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PFK26"]}, "metabolites": {"f26bp_c": 1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "f6p_c": -1.0}, "id": "PFK26", "gene_reaction_rule": "YIL107C or YOL136C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Phosphofructokinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PFK_2"]}, "metabolites": {"h_c": 1.0, "tag6p__D_c": -1.0, "atp_c": -1.0, "tagdp__D_c": 1.0, "adp_c": 1.0}, "id": "PFK_2", "gene_reaction_rule": "YMR205C and YGR240C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Phosphofructokinase (s7p)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PFK_3"]}, "metabolites": {"atp_c": -1.0, "s17bp_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "s7p_c": -1.0}, "id": "PFK_3", "gene_reaction_rule": "YMR205C and YGR240C"}, {"subsystem": "Glutamate metabolism", "name": "Phosphoglucosamine mutase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PGAMT"]}, "metabolites": {"gam6p_c": 1.0, "gam1p_c": -1.0}, "id": "PGAMT", "gene_reaction_rule": "YEL058W"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Phosphoglycerate dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PGCD"]}, "metabolites": {"3php_c": 1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "3pg_c": -1.0}, "id": "PGCD", "gene_reaction_rule": "YER081W or YIL074C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Glucose-6-phosphate isomerase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PGI"]}, "metabolites": {"g6p_c": -1.0, "f6p_c": 1.0}, "id": "PGI", "gene_reaction_rule": "YBR196C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Phosphoglycerate kinase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PGK"]}, "metabolites": {"adp_c": 1.0, "atp_c": -1.0, "13dpg_c": 1.0, "3pg_c": -1.0}, "id": "PGK", "gene_reaction_rule": "YCR012W"}, {"subsystem": "Pentose Phosphate Pathway", "name": "6-phosphogluconolactonase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PGL"]}, "metabolites": {"6pgc_c": 1.0, "h2o_c": -1.0, "6pgl_c": -1.0, "h_c": 1.0}, "id": "PGL", "gene_reaction_rule": "YCR073W_A or YNR034W or YGR248W or YHR163W"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Phosphoglycerate mutase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PGM"]}, "metabolites": {"2pg_c": -1.0, "3pg_c": 1.0}, "id": "PGM", "gene_reaction_rule": "YKL152C or YOL056W or YDL021W"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Phosphoglucomutase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PGMT"]}, "metabolites": {"g6p_c": 1.0, "g1p_c": -1.0}, "id": "PGMT", "gene_reaction_rule": "YKL127W or YMR105C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylglycerol phosphate phosphatase A yeast specific mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PGPPAm_SC"]}, "metabolites": {"pg_SC_m": 0.01, "h2o_m": -1.0, "pi_m": 1.0, "pgp_SC_m": -0.01}, "id": "PGPPAm_SC", "gene_reaction_rule": ""}, {"subsystem": "Arginine and Proline Metabolism", "name": "L 1 pyrroline 3 hydroxy 5 carboxylate dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PHCDm"]}, "metabolites": {"h2o_m": -2.0, "e4hglu_m": 1.0, "1p3h5c_m": -1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 1.0}, "id": "PHCDm", "gene_reaction_rule": "YHR037W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "L 1 Pyrroline 3 hydroxy 5 carboxylate spontaneous conversion to L 4 Hydroxyglutamate semialdehyde mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PHCHGSm"]}, "metabolites": {"1p3h5c_m": -1.0, "h_m": -1.0, "h2o_m": -1.0, "4hglusa_m": 1.0}, "id": "PHCHGSm", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Phenylalanine transaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PHETA1"]}, "metabolites": {"akg_c": -1.0, "phpyr_c": 1.0, "glu__L_c": 1.0, "phe__L_c": -1.0}, "id": "PHETA1", "gene_reaction_rule": "YHR137W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Phenylalanyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PHETRS"]}, "metabolites": {"trnaphe_c": -1.0, "atp_c": -1.0, "phe__L_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "phetrna_c": 1.0}, "id": "PHETRS", "gene_reaction_rule": "YLR060W and YFL022C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Phenylalanyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PHETRSm"]}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "phe__L_m": -1.0, "trnaphe_m": -1.0, "phetrna_m": 1.0, "amp_m": 1.0}, "id": "PHETRSm", "gene_reaction_rule": "YPR047W"}, {"subsystem": "Transport, Mitochondrial", "name": "Phenylalanine mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PHEt2m"]}, "metabolites": {"phe__L_m": -1.0, "h_m": -1.0, "h_c": 1.0, "phe__L_c": 1.0}, "id": "PHEt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L phenylalanine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PHEt2r"]}, "metabolites": {"phe__L_e": -1.0, "h_e": -1.0, "h_c": 1.0, "phe__L_c": 1.0}, "id": "PHEt2r", "gene_reaction_rule": "YCL025C or YKR039W or YDR046C or YOL020W or YBR068C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylinositol 3 phosphate 4 kinase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PI3P4K_SC"]}, "metabolites": {"ptd3ino_SC_c": -0.01, "ptd134bp_SC_c": 0.01, "atp_c": -1.0, "adp_c": 1.0, "h_c": 1.0}, "id": "PI3P4K_SC", "gene_reaction_rule": ""}, {"subsystem": "Phospholipid Biosynthesis", "name": "1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PI45BPP_SC"]}, "metabolites": {"ptd145bp_SC_c": -0.01, "12dgr_SC_c": 0.01, "h2o_c": -1.0, "mi145p_c": 1.0, "h_c": 1.0}, "id": "PI45BPP_SC", "gene_reaction_rule": "YPL268W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylinositol 4 phosphate 5 kinase yeast specfic", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PI4P5K_SC"]}, "metabolites": {"ptd145bp_SC_c": 0.01, "adp_c": 1.0, "h_c": 1.0, "atp_c": -1.0, "ptd4ino_SC_c": -0.01}, "id": "PI4P5K_SC", "gene_reaction_rule": "YDR208W or YFR019W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "1 phosphatidylinositol 3 kinase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PIN3K_SC"]}, "metabolites": {"ptd1ino_SC_c": -0.01, "ptd3ino_SC_c": 0.01, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "PIN3K_SC", "gene_reaction_rule": "YLR240W or YJR066W or YKL203C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylinositol 4 kinase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PIN4K_SC"]}, "metabolites": {"h_c": 1.0, "ptd1ino_SC_c": -0.01, "atp_c": -1.0, "adp_c": 1.0, "ptd4ino_SC_c": 0.01}, "id": "PIN4K_SC", "gene_reaction_rule": "YNL267W or YLR305C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylinositol 4 kinase nuclear yeast specifc", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PIN4Kn_SC"]}, "metabolites": {"h_n": 1.0, "ptd4ino_SC_n": 0.01, "adp_n": 1.0, "ptd1ino_SC_n": -0.01, "atp_n": -1.0}, "id": "PIN4Kn_SC", "gene_reaction_rule": "YNL267W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylinositol synthase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PINOS_SC"]}, "metabolites": {"cmp_c": 1.0, "inost_c": -1.0, "h_c": 1.0, "ptd1ino_SC_c": 0.01, "cdpdag_SC_c": -0.01}, "id": "PINOS_SC", "gene_reaction_rule": "YPR113W"}, {"subsystem": "Transport, Mitochondrial", "name": "Phosphate transporter mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PIt2m"]}, "metabolites": {"pi_c": -1.0, "h_m": 1.0, "pi_m": 1.0, "h_c": -1.0}, "id": "PIt2m", "gene_reaction_rule": "YJR077C"}, {"subsystem": "Transport, Nuclear", "name": "Phosphate nuclear transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PIt2n"]}, "metabolites": {"h_n": 1.0, "pi_c": -1.0, "h_c": -1.0, "pi_n": 1.0}, "id": "PIt2n", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Phosphate peroxisomal transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PIt2p"]}, "metabolites": {"pi_x": 1.0, "pi_c": -1.0, "h_c": -1.0, "h_x": 1.0}, "id": "PIt2p", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Phosphate reversible transport via symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PIt2r"]}, "metabolites": {"pi_c": 1.0, "h_e": -1.0, "pi_e": -1.0, "h_c": 1.0}, "id": "PIt2r", "gene_reaction_rule": "YCR098C or YCR037C or YBR296C or YML123C or YNR013C or YJL198W"}, {"subsystem": "Transport, Vacuolar", "name": "Phosphate vacuolar transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PIt2v"]}, "metabolites": {"h_v": 1.0, "pi_c": -1.0, "h_c": -1.0, "pi_v": 1.0}, "id": "PIt2v", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Phosphate transport via hydroxide ion symport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PIt5m"]}, "metabolites": {"oh1_c": 1.0, "pi_c": -1.0, "pi_m": 1.0, "oh1_m": -1.0}, "id": "PIt5m", "gene_reaction_rule": "YER053C"}, {"subsystem": "Fructose and Mannose Metabolism", "name": "Phosphomannomutase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PMANM"]}, "metabolites": {"man1p_c": -1.0, "man6p_c": 1.0}, "id": "PMANM", "gene_reaction_rule": "YFL045C"}, {"subsystem": "Riboflavin Metabolism", "name": "Pyrimidine phosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PMDPHT"]}, "metabolites": {"4r5au_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "5aprbu_c": -1.0}, "id": "PMDPHT", "gene_reaction_rule": ""}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidyl N methylethanolamine N methyltransferase yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PMETM_SC"]}, "metabolites": {"amet_c": -1.0, "ptd2meeta_SC_c": -0.01, "ahcys_c": 1.0, "h_c": 1.0, "pc_SC_c": 0.01}, "id": "PMETM_SC", "gene_reaction_rule": "YJR073C"}, {"subsystem": "Sterol Biosynthesis", "name": "Phosphomevalonate kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PMEVK"]}, "metabolites": {"5pmev_c": -1.0, "5dpmev_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "PMEVK", "gene_reaction_rule": "YMR220W"}, {"subsystem": "Thiamine Metabolism", "name": "Phosphomethylpyrimidine kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PMPK"]}, "metabolites": {"4ampm_c": -1.0, "2mahmp_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "PMPK", "gene_reaction_rule": "YPL258C or YOL055C"}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Pantothenate kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PNTK"]}, "metabolites": {"4ppan_c": 1.0, "pnto__R_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "PNTK", "gene_reaction_rule": "YDR531W"}, {"subsystem": "Transport, Extracellular", "name": "Pantothenate reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PNTOt2"]}, "metabolites": {"pnto__R_e": -1.0, "h_e": -1.0, "pnto__R_c": 1.0, "h_c": 1.0}, "id": "PNTOt2", "gene_reaction_rule": "YCR028C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Polyamine oxidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["POLYAO"]}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "aprut_c": 1.0, "h2o2_c": 1.0, "N1aspmd_c": -1.0, "aproa_c": 1.0}, "id": "POLYAO", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Poylamine oxidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["POLYAO2"]}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "h2o2_c": 1.0, "N1sprm_c": -1.0, "N1aspmd_c": 1.0, "aproa_c": 1.0}, "id": "POLYAO2", "gene_reaction_rule": ""}, {"subsystem": "Oxidative Phosphorylation", "name": "Inorganic diphosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PPA"]}, "metabolites": {"ppi_c": -1.0, "h2o_c": -1.0, "pi_c": 2.0, "h_c": 1.0}, "id": "PPA", "gene_reaction_rule": "YBR011C"}, {"subsystem": "Oxidative Phosphorylation", "name": "Inorganic diphosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PPAm"]}, "metabolites": {"h2o_m": -1.0, "h_m": 1.0, "ppi_m": -1.0, "pi_m": 2.0}, "id": "PPAm", "gene_reaction_rule": "YMR267W"}, {"subsystem": "Porphyrin and Chlorophyll Metabolism", "name": "Porphobilinogen synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PPBNGS"]}, "metabolites": {"ppbng_c": 1.0, "5aop_c": -2.0, "h_c": 1.0, "h2o_c": 2.0}, "id": "PPBNGS", "gene_reaction_rule": "YGL040C"}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Phosphopantothenoylcysteine decarboxylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PPCDC"]}, "metabolites": {"pan4p_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "4ppcys_c": -1.0}, "id": "PPCDC", "gene_reaction_rule": ""}, {"subsystem": "Anaplerotic reactions", "name": "Phosphoenolpyruvate carboxykinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PPCK"]}, "metabolites": {"pep_c": 1.0, "co2_c": 1.0, "oaa_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "PPCK", "gene_reaction_rule": "YKR097W"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Phosphopentomutase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PPM"]}, "metabolites": {"r5p_c": 1.0, "r1p_c": -1.0}, "id": "PPM", "gene_reaction_rule": "YMR105C or YKL127W"}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Phosphopantothenate-cysteine ligase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PPNCL2"]}, "metabolites": {"cys__L_c": -1.0, "cmp_c": 1.0, "ppi_c": 1.0, "4ppcys_c": 1.0, "4ppan_c": -1.0, "h_c": 1.0, "ctp_c": -1.0}, "id": "PPNCL2", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Prephenate dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PPND"]}, "metabolites": {"34hpp_c": 1.0, "nadh_c": 1.0, "co2_c": 1.0, "pphn_c": -1.0, "nad_c": -1.0}, "id": "PPND", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Prephenate dehydrogenase NADP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PPND2"]}, "metabolites": {"nadph_c": 1.0, "pphn_c": -1.0, "nadp_c": -1.0, "co2_c": 1.0, "34hpp_c": 1.0}, "id": "PPND2", "gene_reaction_rule": "YBR166C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Prephenate dehydratase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PPNDH"]}, "metabolites": {"phpyr_c": 1.0, "pphn_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "h2o_c": 1.0}, "id": "PPNDH", "gene_reaction_rule": "YNL316C"}, {"subsystem": "Transport, Mitochondrial", "name": "Protoporphyrinogen IX mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PPPG9tm"]}, "metabolites": {"pppg9_m": 1.0, "pppg9_c": -1.0}, "id": "PPPG9tm", "gene_reaction_rule": ""}, {"subsystem": "Porphyrin and Chlorophyll Metabolism", "name": "Protoporphyrinogen oxidase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PPPGOm"]}, "metabolites": {"ppp9_m": 2.0, "pppg9_m": -2.0, "h2o_m": 6.0, "o2_m": -3.0}, "id": "PPPGOm", "gene_reaction_rule": "YER014W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Phosphoribosylglycinamide synthase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PRAGSr"]}, "metabolites": {"pram_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "gar_c": 1.0, "pi_c": 1.0, "gly_c": -1.0}, "id": "PRAGSr", "gene_reaction_rule": "YGL234W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Phosphoribosylaminoimidazole synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PRAIS"]}, "metabolites": {"atp_c": -1.0, "air_c": 1.0, "h_c": 2.0, "adp_c": 1.0, "fpram_c": -1.0, "pi_c": 1.0}, "id": "PRAIS", "gene_reaction_rule": "YGL234W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Phosphoribosylanthranilate isomerase (irreversible)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PRAIi"]}, "metabolites": {"2cpr5p_c": 1.0, "pran_c": -1.0}, "id": "PRAIi", "gene_reaction_rule": "YDR007W"}, {"subsystem": "Histidine Metabolism", "name": "Phosphoribosyl-AMP cyclohydrolase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PRAMPC"]}, "metabolites": {"prfp_c": 1.0, "h2o_c": -1.0, "prbamp_c": -1.0}, "id": "PRAMPC", "gene_reaction_rule": "YCL030C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Phosphoribosylaminoimidazolesuccinocarboxamide synthase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PRASCS"]}, "metabolites": {"atp_c": -1.0, "5aizc_c": -1.0, "asp__L_c": -1.0, "25aics_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "PRASCSi", "gene_reaction_rule": "YAR015W"}, {"subsystem": "Histidine Metabolism", "name": "Phosphoribosyl-ATP pyrophosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PRATPP"]}, "metabolites": {"h2o_c": -1.0, "ppi_c": 1.0, "prbamp_c": 1.0, "h_c": 1.0, "prbatp_c": -1.0}, "id": "PRATPP", "gene_reaction_rule": "YCL030C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Phosphoribosylformylglycinamidine synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PRFGS"]}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "glu__L_c": 1.0, "fgam_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "fpram_c": 1.0, "pi_c": 1.0, "gln__L_c": -1.0}, "id": "PRFGS", "gene_reaction_rule": "YGR061C"}, {"subsystem": "Histidine Metabolism", "name": "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PRMICIi"]}, "metabolites": {"prfp_c": -1.0, "prlp_c": 1.0}, "id": "PRMICI", "gene_reaction_rule": "YIL020C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Proline oxidase NAD mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PRO1xm"]}, "metabolites": {"nad_m": -1.0, "h_m": 2.0, "nadh_m": 1.0, "1pyr5c_m": 1.0, "pro__L_m": -1.0}, "id": "PRO1xm", "gene_reaction_rule": "YLR142W"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Prolyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PROTRS"]}, "metabolites": {"atp_c": -1.0, "trnapro_c": -1.0, "ppi_c": 1.0, "pro__L_c": -1.0, "protrna_c": 1.0, "amp_c": 1.0}, "id": "PROTRS", "gene_reaction_rule": "YER087W or YHR020W"}, {"subsystem": "Transport, Extracellular", "name": "L proline reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PROt2r"]}, "metabolites": {"pro__L_c": 1.0, "h_e": -1.0, "h_c": 1.0, "pro__L_e": -1.0}, "id": "PROt2r", "gene_reaction_rule": "YOR348C or YKR039W"}, {"subsystem": "Transport, Mitochondrial", "name": "L proline transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PROtm"]}, "metabolites": {"pro__L_c": -1.0, "pro__L_m": 1.0}, "id": "PROtm", "gene_reaction_rule": ""}, {"subsystem": "Histidine Metabolism", "name": "Phosphoribosylpyrophosphate synthetase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PRPPS"]}, "metabolites": {"prpp_c": 1.0, "r5p_c": -1.0, "h_c": 1.0, "atp_c": -1.0, "amp_c": 1.0}, "id": "PRPPS", "gene_reaction_rule": "YKL181W or YER099C or YHL011C or YBL068W or YOL061W"}, {"subsystem": "Transport, Mitochondrial", "name": "PRPP reversible transport mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PRPPtm"]}, "metabolites": {"prpp_m": 1.0, "prpp_c": -1.0}, "id": "PRPPtm", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "3-phosphoshikimate 1-carboxyvinyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PSCVTi"]}, "metabolites": {"pep_c": -1.0, "pi_c": 1.0, "skm5p_c": -1.0, "3psme_c": 1.0}, "id": "PSCVT", "gene_reaction_rule": "YDR127W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylserine decarboxylase yeast specific Golgi", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PSERDg_SC"]}, "metabolites": {"h_g": -1.0, "pe_SC_g": 0.01, "ps_SC_g": -0.01, "co2_g": 1.0}, "id": "PSERDg_SC", "gene_reaction_rule": "YGR170W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylserine decarboxylase yeast specific mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PSERDm_SC"]}, "metabolites": {"pe_SC_m": 0.01, "h_m": -1.0, "co2_m": 1.0, "ps_SC_m": -0.01}, "id": "PSERDm_SC", "gene_reaction_rule": "YNL169C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylserine decarboxylase yeast specific vacuolar", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PSERDv_SC"]}, "metabolites": {"h_v": -1.0, "pe_SC_v": 0.01, "ps_SC_v": -0.01, "co2_v": 1.0}, "id": "PSERDv_SC", "gene_reaction_rule": "YGR170W"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylserine synthase yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PSERS_SC"]}, "metabolites": {"ps_SC_c": 0.01, "ser__L_c": -1.0, "cdpdag_SC_c": -0.01, "h_c": 1.0, "cmp_c": 1.0}, "id": "PSERS_SC", "gene_reaction_rule": "YER026C"}, {"subsystem": "Phospholipid Biosynthesis", "name": "Phosphatidylserine synthase yeast specific mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PSERSm_SC"]}, "metabolites": {"cdpdag_SC_m": -0.01, "h_m": 1.0, "ser__L_m": -1.0, "ps_SC_m": 0.01, "cmp_m": 1.0}, "id": "PSERSm_SC", "gene_reaction_rule": "YER026C"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Phosphoserine transaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PSERT"]}, "metabolites": {"akg_c": 1.0, "3php_c": -1.0, "glu__L_c": -1.0, "pser__L_c": 1.0}, "id": "PSERT", "gene_reaction_rule": "YOR184W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Phytosphingosine phosphate lyase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PSPHPL"]}, "metabolites": {"2hhxdal_c": 1.0, "psph1p_c": -1.0, "ethamp_c": 1.0}, "id": "PSPHPL", "gene_reaction_rule": "YDR294C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Phytosphingosine synthesis", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PSPHS"]}, "metabolites": {"psphings_c": 1.0, "o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "sphgn_c": -1.0, "h_c": -1.0}, "id": "PSPHS", "gene_reaction_rule": "YDR297W"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Phosphoserine phosphatase (L-serine)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PSP_L"]}, "metabolites": {"h2o_c": -1.0, "pser__L_c": -1.0, "ser__L_c": 1.0, "pi_c": 1.0}, "id": "PSP_L", "gene_reaction_rule": "YGR208W"}, {"subsystem": "Transport, Golgi Apparatus", "name": "Phosphatidylserine Golgi transport yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PStg_SC"]}, "metabolites": {"ps_SC_c": -1.0, "ps_SC_g": 1.0}, "id": "PStg_SC", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Phosphatidylserine mitochondrial transport yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PStm_SC"]}, "metabolites": {"ps_SC_c": -1.0, "ps_SC_m": 1.0}, "id": "PStm_SC", "gene_reaction_rule": ""}, {"subsystem": "Transport, Vacuolar", "name": "Phosphatidylserine vacuolar transport yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PStv_SC"]}, "metabolites": {"ps_SC_c": -1.0, "ps_SC_v": 1.0}, "id": "PStv_SC", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "Phosphatidyl 1D myo insoitol nuclear transport yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PTD1INOtn_SC"]}, "metabolites": {"ptd1ino_SC_n": 1.0, "ptd1ino_SC_c": -1.0}, "id": "PTD1INOtn_SC", "gene_reaction_rule": ""}, {"subsystem": "Transport, Nuclear", "name": "Phosphatidyl 1D myo 4 inositol nuclear transport yeast specific", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PTD4INOtn_SC"]}, "metabolites": {"ptd4ino_SC_n": 1.0, "ptd4ino_SC_c": -1.0}, "id": "PTD4INOtn_SC", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Pantetheine-phosphate adenylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PTPATi"]}, "metabolites": {"pan4p_c": -1.0, "dpcoa_c": 1.0, "ppi_c": 1.0, "h_c": -1.0, "atp_c": -1.0}, "id": "PTPATi", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA Biosynthesis", "name": "Panthetheine phosphate adenylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PTPATim"]}, "metabolites": {"atp_m": -1.0, "ppi_m": 1.0, "h_m": -1.0, "dpcoa_m": 1.0, "pan4p_m": -1.0}, "id": "PTPATim", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "PTRCt2", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PTRCt2"]}, "metabolites": {"ptrc_c": 1.0, "h_e": -1.0, "h_c": 1.0, "ptrc_e": -1.0}, "id": "PTRCt2", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Purine-nucleoside phosphorylase (Adenosine)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PUNP1"]}, "metabolites": {"ade_c": 1.0, "pi_c": -1.0, "adn_c": -1.0, "r1p_c": 1.0}, "id": "PUNP1", "gene_reaction_rule": "YLR209C"}, {"subsystem": "NAD Biosynthesis", "name": "Purine nucleoside phosphorylase Adenosine mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PUNP1m"]}, "metabolites": {"r1p_m": 1.0, "adn_m": -1.0, "ade_m": 1.0, "pi_m": -1.0}, "id": "PUNP1m", "gene_reaction_rule": "YLR209C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Purine-nucleoside phosphorylase (Deoxyadenosine)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PUNP2"]}, "metabolites": {"dad_2_c": -1.0, "ade_c": 1.0, "pi_c": -1.0, "2dr1p_c": 1.0}, "id": "PUNP2", "gene_reaction_rule": "YLR209C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Purine-nucleoside phosphorylase (Guanosine)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PUNP3"]}, "metabolites": {"gua_c": 1.0, "pi_c": -1.0, "r1p_c": 1.0, "gsn_c": -1.0}, "id": "PUNP3", "gene_reaction_rule": "YLR209C"}, {"subsystem": "NAD Biosynthesis", "name": "Purine nucleoside phosphorylase Guanosine mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PUNP3m"]}, "metabolites": {"r1p_m": 1.0, "gsn_m": -1.0, "gua_m": 1.0, "pi_m": -1.0}, "id": "PUNP3m", "gene_reaction_rule": "YLR209C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Purine-nucleoside phosphorylase (Deoxyguanosine)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PUNP4"]}, "metabolites": {"dgsn_c": -1.0, "gua_c": 1.0, "pi_c": -1.0, "2dr1p_c": 1.0}, "id": "PUNP4", "gene_reaction_rule": "YLR209C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Purine-nucleoside phosphorylase (Inosine)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PUNP5"]}, "metabolites": {"pi_c": -1.0, "hxan_c": 1.0, "r1p_c": 1.0, "ins_c": -1.0}, "id": "PUNP5", "gene_reaction_rule": "YLR209C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Purine-nucleoside phosphorylase (Deoxyinosine)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PUNP6"]}, "metabolites": {"din_c": -1.0, "pi_c": -1.0, "2dr1p_c": 1.0, "hxan_c": 1.0}, "id": "PUNP6", "gene_reaction_rule": "YLR209C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Purine-nucleoside phosphorylase (Xanthosine)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PUNP7"]}, "metabolites": {"pi_c": -1.0, "xan_c": 1.0, "r1p_c": 1.0, "xtsn_c": -1.0}, "id": "PUNP7", "gene_reaction_rule": "YLR209C"}, {"subsystem": "Pyridoxine Metabolism", "name": "Pyridoxamine 5'-phosphate oxidase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PYAM5PO"]}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "pydx5p_c": 1.0, "h2o2_c": 1.0, "pyam5p_c": -1.0, "nh4_c": 1.0}, "id": "PYAM5PO", "gene_reaction_rule": "YBR035C"}, {"subsystem": "Pyridoxine Metabolism", "name": "Pyridoxamine kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PYDAMK"]}, "metabolites": {"pydam_c": -1.0, "pyam5p_c": 1.0, "h_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "PYDAMK", "gene_reaction_rule": ""}, {"subsystem": "Pyridoxine Metabolism", "name": "Pyridoxal kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PYDXK"]}, "metabolites": {"atp_c": -1.0, "pydx5p_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "pydx_c": -1.0}, "id": "PYDXK", "gene_reaction_rule": ""}, {"subsystem": "Pyridoxine Metabolism", "name": "Pyridoxine kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PYDXNK"]}, "metabolites": {"pydxn_c": -1.0, "h_c": 1.0, "pdx5p_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "PYDXNK", "gene_reaction_rule": ""}, {"subsystem": "Pyridoxine Metabolism", "name": "Pyridoxine oxidase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PYDXNO"]}, "metabolites": {"pydxn_c": -1.0, "o2_c": -1.0, "pydx_c": 1.0, "h2o2_c": 1.0}, "id": "PYDXNO", "gene_reaction_rule": "YBR035C"}, {"subsystem": "Pyridoxine Metabolism", "name": "Pyridoxal oxidase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PYDXO"]}, "metabolites": {"o2_c": -0.5, "h2o_c": -2.0, "h2o2_c": 2.0, "pydx_c": -1.0, "pydam_c": 1.0, "nh4_c": -1.0}, "id": "PYDXO", "gene_reaction_rule": "YBR035C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Pyruvate kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PYK"]}, "metabolites": {"pep_c": -1.0, "pyr_c": 1.0, "h_c": -1.0, "adp_c": -1.0, "atp_c": 1.0}, "id": "PYK", "gene_reaction_rule": "YAL038W or YOR347C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Pyrimidine-nucleoside phosphorylase (uracil)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PYNP2r"]}, "metabolites": {"uri_c": -1.0, "pi_c": -1.0, "r1p_c": 1.0, "ura_c": 1.0}, "id": "PYNP2r", "gene_reaction_rule": ""}, {"subsystem": "Glutamate metabolism", "name": "D1 pyrroline 5 carboxylate dehydrogenase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PYR5CDm"]}, "metabolites": {"glu__L_m": 1.0, "nadph_m": 1.0, "h2o_m": -1.0, "nadp_m": -1.0, "glu5sa_m": -1.0, "h_m": 2.0}, "id": "PYR5CDm", "gene_reaction_rule": "YHR037W"}, {"subsystem": "Pyruvate Metabolism", "name": "Pyruvate decarboxylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PYRDC"]}, "metabolites": {"acald_c": 1.0, "pyr_c": -1.0, "co2_c": 1.0, "h_c": -1.0}, "id": "PYRDC", "gene_reaction_rule": "YLR134W or YGR087C or YLR044C"}, {"subsystem": "Transport, Extracellular", "name": "Pyruvate transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PYRt2"]}, "metabolites": {"pyr_c": 1.0, "h_e": -1.0, "pyr_e": -1.0, "h_c": 1.0}, "id": "PYRt2", "gene_reaction_rule": "YKL217W"}, {"subsystem": "Transport, Mitochondrial", "name": "Pyruvate mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PYRt2m"]}, "metabolites": {"pyr_c": -1.0, "h_m": 1.0, "pyr_m": 1.0, "h_c": -1.0}, "id": "PYRt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Pyruvate peroxisomal transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["PYRt2p"]}, "metabolites": {"pyr_x": 1.0, "pyr_c": -1.0, "h_c": -1.0, "h_x": 1.0}, "id": "PYRt2p", "gene_reaction_rule": ""}, {"subsystem": "Folate Metabolism", "name": "QULNS", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["QULNS"]}, "metabolites": {"h2o_c": 2.0, "iasp_c": -1.0, "dhap_c": -1.0, "quln_c": 1.0, "h_c": 1.0, "pi_c": 1.0}, "id": "QULNS_1", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Quinolinate reversible mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["QULNtm"]}, "metabolites": {"quln_m": 1.0, "quln_c": -1.0}, "id": "QULNtm", "gene_reaction_rule": ""}, {"subsystem": "Galactose metabolism", "name": "Raffinose galactohydrolase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RAFGH"]}, "metabolites": {"raffin_c": -1.0, "h2o_c": -1.0, "sucr_c": 1.0, "gal_c": 1.0}, "id": "RAFGH", "gene_reaction_rule": "YBR184W"}, {"subsystem": "Riboflavin Metabolism", "name": "Riboflavin kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RBFK"]}, "metabolites": {"atp_c": -1.0, "fmn_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "ribflv_c": -1.0}, "id": "RBFK", "gene_reaction_rule": "YDR236C"}, {"subsystem": "Riboflavin Metabolism", "name": "Riboflavin kinase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RBFKm"]}, "metabolites": {"atp_m": -1.0, "adp_m": 1.0, "fmn_m": 1.0, "h_m": 1.0, "ribflv_m": -1.0}, "id": "RBFKm", "gene_reaction_rule": "YDR236C"}, {"subsystem": "Riboflavin Metabolism", "name": "Riboflavin synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RBFSa"]}, "metabolites": {"4r5au_c": -1.0, "h2o_c": 2.0, "pi_c": 1.0, "dmlz_c": 1.0, "db4p_c": -1.0}, "id": "RBFSa", "gene_reaction_rule": "YOL143C"}, {"subsystem": "Riboflavin Metabolism", "name": "Riboflavin synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RBFSb"]}, "metabolites": {"4r5au_c": 1.0, "dmlz_c": -2.0, "ribflv_c": 1.0}, "id": "RBFSb", "gene_reaction_rule": "YBR256C"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Ribokinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RBK"]}, "metabolites": {"r5p_c": 1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "rib__D_c": -1.0}, "id": "RBK", "gene_reaction_rule": "YCR036W"}, {"subsystem": "Transport, Extracellular", "name": "Riboflavin transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RIBFLVt2"]}, "metabolites": {"ribflv_e": -1.0, "h_e": -1.0, "h_c": 1.0, "ribflv_c": 1.0}, "id": "RIBFLVt2", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Riboflavin reversible mitochondrial transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["RIBFLVtm"]}, "metabolites": {"ribflv_m": 1.0, "ribflv_c": -1.0}, "id": "RIBFLVtm", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Ribose transport in via proton symporter", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RIBt2"]}, "metabolites": {"rib__D_e": -1.0, "h_e": -1.0, "h_c": 1.0, "rib__D_c": 1.0}, "id": "RIBt2", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside-diphosphate reductase (ADP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNDR1"]}, "metabolites": {"dadp_c": 1.0, "trdox_c": 1.0, "trdrd_c": -1.0, "adp_c": -1.0, "h2o_c": 1.0}, "id": "RNDR1", "gene_reaction_rule": "(YIL066C and YJL026W) or (YER070W and YJL026W)"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside diphosphate reductase nuclear", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNDR1n"]}, "metabolites": {"trdrd_n": -1.0, "trdox_n": 1.0, "adp_n": -1.0, "dadp_n": 1.0, "h2o_n": 1.0}, "id": "RNDR1n", "gene_reaction_rule": "(YER070W and YGR180C) or (YGR180C and YIL066C)"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside-diphosphate reductase (GDP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNDR2"]}, "metabolites": {"trdox_c": 1.0, "dgdp_c": 1.0, "gdp_c": -1.0, "h2o_c": 1.0, "trdrd_c": -1.0}, "id": "RNDR2", "gene_reaction_rule": "YER070W and YJL026W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside diphosphate reductase GDP nuclear", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNDR2n"]}, "metabolites": {"trdrd_n": -1.0, "gdp_n": -1.0, "h2o_n": 1.0, "dgdp_n": 1.0, "trdox_n": 1.0}, "id": "RNDR2n", "gene_reaction_rule": "YER070W and YGR180C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside-diphosphate reductase (CDP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNDR3"]}, "metabolites": {"cdp_c": -1.0, "trdox_c": 1.0, "trdrd_c": -1.0, "h2o_c": 1.0, "dcdp_c": 1.0}, "id": "RNDR3", "gene_reaction_rule": "YER070W and YJL026W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside diphosphate reductase CDP nuclear", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNDR3n"]}, "metabolites": {"trdrd_n": -1.0, "dcdp_n": 1.0, "trdox_n": 1.0, "cdp_n": -1.0, "h2o_n": 1.0}, "id": "RNDR3n", "gene_reaction_rule": "YER070W and YGR180C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside-diphosphate reductase (UDP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNDR4"]}, "metabolites": {"udp_c": -1.0, "trdox_c": 1.0, "dudp_c": 1.0, "h2o_c": 1.0, "trdrd_c": -1.0}, "id": "RNDR4", "gene_reaction_rule": "YER070W and YJL026W"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside diphosphate reductase UDP nuclear", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNDR4n"]}, "metabolites": {"trdrd_n": -1.0, "dudp_n": 1.0, "udp_n": -1.0, "h2o_n": 1.0, "trdox_n": 1.0}, "id": "RNDR4n", "gene_reaction_rule": "YER070W and YGR180C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside triphosphate reductase ATP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNTR1"]}, "metabolites": {"datp_c": 1.0, "trdox_c": 1.0, "trdrd_c": -1.0, "atp_c": -1.0, "h2o_c": 1.0}, "id": "RNTR1", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside triphosphate reductase GTP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNTR2"]}, "metabolites": {"trdox_c": 1.0, "h2o_c": 1.0, "dgtp_c": 1.0, "gtp_c": -1.0, "trdrd_c": -1.0}, "id": "RNTR2", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside triphosphate reductase CTP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNTR3"]}, "metabolites": {"ctp_c": -1.0, "h2o_c": 1.0, "trdox_c": 1.0, "trdrd_c": -1.0, "dctp_c": 1.0}, "id": "RNTR3", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Ribonucleoside triphosphate reductase UTP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["RNTR4"]}, "metabolites": {"utp_c": -1.0, "trdox_c": 1.0, "dutp_c": 1.0, "h2o_c": 1.0, "trdrd_c": -1.0}, "id": "RNTR4", "gene_reaction_rule": ""}, {"subsystem": "Pentose Phosphate Pathway", "name": "Ribulose 5-phosphate 3-epimerase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["RPE"]}, "metabolites": {"xu5p__D_c": 1.0, "ru5p__D_c": -1.0}, "id": "RPE", "gene_reaction_rule": "YJL121C"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Ribose-5-phosphate isomerase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["RPI"]}, "metabolites": {"r5p_c": -1.0, "ru5p__D_c": 1.0}, "id": "RPI", "gene_reaction_rule": "YOR095C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "Saccharopine dehydrogenase NADP L glutamate forming ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SACCD1"]}, "metabolites": {"h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "glu__L_c": -1.0, "saccrp__L_c": 1.0, "h_c": -1.0, "L2aadp6sa_c": -1.0}, "id": "SACCD1", "gene_reaction_rule": "YNR050C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "Saccharopine dehydrogenase NAD L lysine forming ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SACCD2"]}, "metabolites": {"akg_c": 1.0, "h2o_c": -1.0, "lys__L_c": 1.0, "saccrp__L_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "SACCD2", "gene_reaction_rule": "YIR034C"}, {"subsystem": "Cysteine Metabolism", "name": "Sulfate adenylyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SADT"]}, "metabolites": {"so4_c": -1.0, "ppi_c": 1.0, "h_c": -1.0, "atp_c": -1.0, "aps_c": 1.0}, "id": "SADT", "gene_reaction_rule": "YJR010W"}, {"subsystem": "Sterol Biosynthesis", "name": "S adenosyl methionine delta 24 sterol c methyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SAM24MT"]}, "metabolites": {"amet_c": -1.0, "ahcys_c": 1.0, "zymst_c": -1.0, "h_c": 1.0, "fecost_c": 1.0}, "id": "SAM24MT", "gene_reaction_rule": "YML008C"}, {"subsystem": "Sphingolipid Metabolism", "name": "SBPP1", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SBPP1"]}, "metabolites": {"sph1p_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "sphgn_c": 1.0}, "id": "SBPP1", "gene_reaction_rule": "YJL134W or YKR053C"}, {"subsystem": "Sphingolipid Metabolism", "name": "SBPP2", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SBPP2"]}, "metabolites": {"psphings_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "psph1p_c": -1.0}, "id": "SBPP2", "gene_reaction_rule": "YKR053C or YJL134W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "D sorbitol dehydrogenase D fructose producing ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SBTD_D2"]}, "metabolites": {"fru_c": 1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "sbt__D_c": -1.0}, "id": "SBTD_D2", "gene_reaction_rule": "YJR159W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "L sorbitol dehydrogenase L sorbose producing ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SBTD_L"]}, "metabolites": {"srb__L_c": 1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "sbt__L_c": -1.0}, "id": "SBTD_L", "gene_reaction_rule": "YJR159W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "D sorbitol reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SBTR"]}, "metabolites": {"glc__D_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "sbt__D_c": 1.0}, "id": "SBTR", "gene_reaction_rule": "YHR104W"}, {"subsystem": "Transport, Extracellular", "name": "D sorbitol transport via passive diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SBT_Dt"]}, "metabolites": {"sbt__D_e": -1.0, "sbt__D_c": 1.0}, "id": "SBT_Dt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L sorbitol transport via passive diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SBT_Lt"]}, "metabolites": {"sbt__L_e": -1.0, "sbt__L_c": 1.0}, "id": "SBT_Lt", "gene_reaction_rule": ""}, {"subsystem": "Cysteine Metabolism", "name": "Serine O-acetyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SERATi"]}, "metabolites": {"ser__L_c": -1.0, "acser_c": 1.0, "coa_c": 1.0, "accoa_c": -1.0}, "id": "SERAT", "gene_reaction_rule": ""}, {"subsystem": "Glycine and Serine Metabolism", "name": "L-serine deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SERD_L"]}, "metabolites": {"pyr_c": 1.0, "ser__L_c": -1.0, "nh4_c": 1.0}, "id": "SERD_L", "gene_reaction_rule": "YCL064C or YIL167W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Serine C palmitoyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SERPT"]}, "metabolites": {"3dsphgn_c": 1.0, "pmtcoa_c": -1.0, "ser__L_c": -1.0, "coa_c": 1.0, "h_c": -1.0, "co2_c": 1.0}, "id": "SERPT", "gene_reaction_rule": "YDR062W and YMR296C"}, {"subsystem": "Glycine and Serine Metabolism", "name": "Seryl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SERTRS"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "sertrna_c": 1.0, "ser__L_c": -1.0, "amp_c": 1.0, "trnaser_c": -1.0}, "id": "SERTRS", "gene_reaction_rule": "YHR011W or YDR023W"}, {"subsystem": "Transport, Mitochondrial", "name": "Serine mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SERt2m"]}, "metabolites": {"ser__L_c": -1.0, "h_m": 1.0, "ser__L_m": 1.0, "h_c": -1.0}, "id": "SERt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L serine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SERt2r"]}, "metabolites": {"ser__L_c": 1.0, "h_e": -1.0, "ser__L_e": -1.0, "h_c": 1.0}, "id": "SERt2r", "gene_reaction_rule": "YCL025C or YFL055W or YPL265W or YDR508C or YKR039W"}, {"subsystem": "Methane Metabolism", "name": "S-Formylglutathione hydralase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SFGTH"]}, "metabolites": {"h2o_c": -1.0, "gthrd_c": 1.0, "h_c": 1.0, "for_c": 1.0, "Sfglutth_c": -1.0}, "id": "SFGTHi", "gene_reaction_rule": "YJL068C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Shikimate dehydrogenase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SHK3D"]}, "metabolites": {"3dhsk_c": -1.0, "skm_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0}, "id": "SHK3Dr", "gene_reaction_rule": "YDR127W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Shikimate kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SHKK"]}, "metabolites": {"atp_c": -1.0, "skm_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "skm5p_c": 1.0}, "id": "SHKK", "gene_reaction_rule": "YDR127W"}, {"subsystem": "Methionine Metabolism", "name": "O-succinylhomoserine lyase (L-cysteine)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SHSL1"]}, "metabolites": {"cys__L_c": -1.0, "succ_c": 1.0, "suchms_c": -1.0, "h_c": 1.0, "cyst__L_c": 1.0}, "id": "SHSL1", "gene_reaction_rule": ""}, {"subsystem": "Methionine Metabolism", "name": "O succinylhomoserine lyase elimination reversible", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SHSL4r"]}, "metabolites": {"h2o_c": -1.0, "2obut_c": 1.0, "succ_c": 1.0, "suchms_c": -1.0, "h_c": 1.0, "nh4_c": 1.0}, "id": "SHSL4r", "gene_reaction_rule": "YML082W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Sphingolipid long chain base kinase sphinganine ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SLCBK1"]}, "metabolites": {"sph1p_c": 1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "sphgn_c": -1.0}, "id": "SLCBK1", "gene_reaction_rule": "YLR260W or YOR171C"}, {"subsystem": "Sphingolipid Metabolism", "name": "Sphingolipid long chain base kinase phytosphingosine ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SLCBK2"]}, "metabolites": {"psph1p_c": 1.0, "psphings_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "SLCBK2", "gene_reaction_rule": "YOR171C or YLR260W"}, {"subsystem": "Cysteine Metabolism", "name": "Sulfate adenylyltransferase ADP ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SLFAT"]}, "metabolites": {"so4_c": -1.0, "pi_c": 1.0, "h_c": -1.0, "adp_c": -1.0, "aps_c": 1.0}, "id": "SLFAT", "gene_reaction_rule": "YCL050C"}, {"subsystem": "Transport, Extracellular", "name": "Sulfate irreversible uniport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SO4ti"]}, "metabolites": {"so4_c": 1.0, "so4_e": -1.0}, "id": "SO4ti", "gene_reaction_rule": "YBR294W or YLR092W or YGR125W"}, {"subsystem": "Sphingolipid Metabolism", "name": "Sphinganine phosphate lyase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SPHPL"]}, "metabolites": {"sph1p_c": -1.0, "hxdcal_c": 1.0, "ethamp_c": 1.0}, "id": "SPHPL", "gene_reaction_rule": "YDR294C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Spermidine acetyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SPMDAT1"]}, "metabolites": {"spmd_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "accoa_c": -1.0, "N1aspmd_c": 1.0}, "id": "SPMDAT1", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "SPMDt2", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SPMDt2"]}, "metabolites": {"spmd_c": 1.0, "h_e": -1.0, "spmd_e": -1.0, "h_c": 1.0}, "id": "SPMDt2", "gene_reaction_rule": ""}, {"subsystem": "Arginine and Proline Metabolism", "name": "Spermidine synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SPMS"]}, "metabolites": {"ptrc_c": -1.0, "spmd_c": 1.0, "5mta_c": 1.0, "h_c": 1.0, "ametam_c": -1.0}, "id": "SPMS", "gene_reaction_rule": "YPR069C"}, {"subsystem": "Arginine and Proline Metabolism", "name": "Spermine synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SPRMS"]}, "metabolites": {"ametam_c": -1.0, "spmd_c": -1.0, "5mta_c": 1.0, "sprm_c": 1.0, "h_c": 1.0}, "id": "SPRMS", "gene_reaction_rule": "YLR146C"}, {"subsystem": "Transport, Extracellular", "name": "SPRMti", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SPRMti"]}, "metabolites": {"sprm_c": 1.0, "sprm_e": -1.0}, "id": "SPRMti", "gene_reaction_rule": ""}, {"subsystem": "Transport, Endoplasmic Reticular", "name": "Squalene 2 3 epoxide endoplamic reticular transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SQ23EPXter"]}, "metabolites": {"Ssq23epx_r": -1.0, "Ssq23epx_c": 1.0}, "id": "SQ23EPXter", "gene_reaction_rule": ""}, {"subsystem": "Sterol Biosynthesis", "name": "Squalene epoxidase endoplasmic reticular NADP ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SQLEr"]}, "metabolites": {"h_r": -1.0, "Ssq23epx_r": 1.0, "o2_r": -1.0, "nadp_r": 1.0, "h2o_r": 1.0, "nadph_r": -1.0, "sql_r": -1.0}, "id": "SQLEr", "gene_reaction_rule": "YGR175C"}, {"subsystem": "Sterol Biosynthesis", "name": "Squalene synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SQLS"]}, "metabolites": {"nadp_c": 1.0, "nadph_c": -1.0, "ppi_c": 2.0, "sql_c": 1.0, "h_c": -1.0, "frdp_c": -2.0}, "id": "SQLS", "gene_reaction_rule": "YHR190W"}, {"subsystem": "Transport, Endoplasmic Reticular", "name": "Squalene endoplamic reticular transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SQLter"]}, "metabolites": {"sql_r": 1.0, "sql_c": -1.0}, "id": "SQLter", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L sorbose reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SRB_Lt"]}, "metabolites": {"srb__L_c": 1.0, "srb__L_e": -1.0}, "id": "SRB_Lt", "gene_reaction_rule": ""}, {"subsystem": "Glutamate metabolism", "name": "Succinate-semialdehyde dehydrogenase (NADP)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SSALy"]}, "metabolites": {"h2o_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "sucsal_c": -1.0, "succ_c": 1.0, "h_c": 2.0}, "id": "SSALy", "gene_reaction_rule": "YBR006W"}, {"subsystem": "Transport, Extracellular", "name": "Succinate transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SUCCt2r"]}, "metabolites": {"succ_c": 1.0, "h_e": -1.0, "succ_e": -1.0, "h_c": 1.0}, "id": "SUCCt2r", "gene_reaction_rule": ""}, {"subsystem": "Transport, Mitochondrial", "name": "Succinate transport mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SUCCtm"]}, "metabolites": {"succ_c": -1.0, "pi_c": 1.0, "succ_m": 1.0, "pi_m": -1.0}, "id": "SUCCtm", "gene_reaction_rule": "YLR348C"}, {"subsystem": "Oxidative Phosphorylation", "name": "Succinate dehydrogenase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SUCD1m"]}, "metabolites": {"fad_m": -1.0, "fadh2_m": 1.0, "succ_m": -1.0, "fum_m": 1.0}, "id": "SUCD1m", "gene_reaction_rule": "(YKL141W and YDR178W and YLL041C and YJL045W) or (YKL141W and YDR178W and YLL041C and YKL148C) or (YDR178W and YLL041C and YMR118C and YKL148C) or (YLR164W and YKL141W and YLL041C and YKL148C)"}, {"subsystem": "Citric Acid Cycle", "name": "Succinate dehydrogenase ubiquinone 6 mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SUCD2_u6m"]}, "metabolites": {"q6_m": -1.0, "succ_m": -1.0, "fum_m": 1.0, "q6h2_m": 1.0}, "id": "SUCD2_u6m", "gene_reaction_rule": "(YKL141W and YDR178W and YLL041C and YJL045W) or (YKL141W and YDR178W and YLL041C and YKL148C) or (YDR178W and YLL041C and YMR118C and YKL148C) or (YLR164W and YKL141W and YLL041C and YKL148C)"}, {"subsystem": "Oxidative Phosphorylation", "name": "Succinate dehydrogenase ubiquinone 6 mitochondrial", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SUCD3_u6m"]}, "metabolites": {"fad_m": 1.0, "q6_m": -1.0, "fadh2_m": -1.0, "q6h2_m": 1.0}, "id": "SUCD3_u6m", "gene_reaction_rule": "(YKL141W and YDR178W and YLL041C and YJL045W) or (YKL141W and YDR178W and YLL041C and YKL148C) or (YDR178W and YLL041C and YMR118C and YKL148C) or (YLR164W and YKL141W and YLL041C and YKL148C)"}, {"subsystem": "Transport, Mitochondrial", "name": "Succinate fumarate transport mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SUCFUMtm"]}, "metabolites": {"succ_c": -1.0, "fum_c": 1.0, "succ_m": 1.0, "fum_m": -1.0}, "id": "SUCFUMtm", "gene_reaction_rule": "YJR095W"}, {"subsystem": "Citric Acid Cycle", "name": "Succinate CoA ligase ADP forming ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SUCOASm"]}, "metabolites": {"succoa_m": 1.0, "atp_m": -1.0, "pi_m": 1.0, "adp_m": 1.0, "coa_m": -1.0, "succ_m": -1.0}, "id": "SUCOASm", "gene_reaction_rule": "YOR142W and YGR244C"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Sucrose hydrolyzing enxyme extracellular", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SUCRe"]}, "metabolites": {"fru_e": 1.0, "h2o_e": -1.0, "sucr_e": -1.0, "glc__D_e": 1.0}, "id": "SUCRe", "gene_reaction_rule": "YIL162W"}, {"subsystem": "Transport, Extracellular", "name": "Sucrose transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["SUCRt2"]}, "metabolites": {"sucr_c": 1.0, "h_e": -1.0, "h_c": 1.0, "sucr_e": -1.0}, "id": "SUCRt2", "gene_reaction_rule": ""}, {"subsystem": "Cysteine Metabolism", "name": "Sulfite reductase NADPH2 ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["SULR"]}, "metabolites": {"h2o_c": -3.0, "nadp_c": -3.0, "nadph_c": 3.0, "so3_c": 1.0, "h2s_c": -1.0, "h_c": 5.0}, "id": "SULR", "gene_reaction_rule": "YJR137C or YFR030W"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Transaldolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TALA"]}, "metabolites": {"e4p_c": 1.0, "g3p_c": -1.0, "s7p_c": -1.0, "f6p_c": 1.0}, "id": "TALA", "gene_reaction_rule": "YLR354C or YGR043C"}, {"subsystem": "Folate Metabolism", "name": "Tetrahydrofolate aminomethyltransferase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THFATm"]}, "metabolites": {"h_m": 1.0, "h2o_m": -1.0, "5fthf_m": 1.0, "methf_m": -1.0}, "id": "THFATm", "gene_reaction_rule": "YDR019C and YMR189W and YAL044C and (YBR221C and YER178W)"}, {"subsystem": "Folate Metabolism", "name": "TetrahydrofolateL glutamate gamma ligase ADP forming ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["THFGLUS"]}, "metabolites": {"atp_c": -1.0, "thfglu_c": 1.0, "glu__L_c": -1.0, "thf_c": -1.0, "adp_c": 1.0, "pi_c": 1.0, "h_c": 1.0}, "id": "THFGLUS", "gene_reaction_rule": "YKL132C or YMR113W or YOR241W"}, {"subsystem": "Transport, Mitochondrial", "name": "THFtm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["THFtm"]}, "metabolites": {"thf_m": 1.0, "thf_c": -1.0}, "id": "THFtm", "gene_reaction_rule": ""}, {"subsystem": "Thiamine Metabolism", "name": "Thiamin diphosphatase extracellular", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THMDPe"]}, "metabolites": {"thm_e": 1.0, "h_e": 1.0, "h2o_e": -2.0, "pi_e": 2.0, "thmpp_e": -1.0}, "id": "THMDPe", "gene_reaction_rule": "YBR092C"}, {"subsystem": "Transport, Extracellular", "name": "Thymidine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THMDt2"]}, "metabolites": {"thymd_e": -1.0, "h_e": -1.0, "h_c": 1.0, "thymd_c": 1.0}, "id": "THMDt2", "gene_reaction_rule": ""}, {"subsystem": "Thiamine Metabolism", "name": "Thiamin phosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THMP"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "thm_c": 1.0, "thmmp_c": -1.0}, "id": "THMP", "gene_reaction_rule": ""}, {"subsystem": "Thiamine Metabolism", "name": "Thiamin phosphatase extracellular", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THMPe"]}, "metabolites": {"thmmp_e": -1.0, "h2o_e": -1.0, "thm_e": 1.0, "pi_e": 1.0}, "id": "THMPe", "gene_reaction_rule": "YBR092C"}, {"subsystem": "Transport, Extracellular", "name": "Thiamine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THMt2"]}, "metabolites": {"thm_c": 1.0, "h_e": -1.0, "thm_e": -1.0, "h_c": 1.0}, "id": "THMt2", "gene_reaction_rule": "YLR237W or YOR192C or YOR071C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "THRA", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THRA"]}, "metabolites": {"acald_c": -1.0, "thr__L_c": 1.0, "gly_c": -1.0}, "id": "THRA", "gene_reaction_rule": "YEL046C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "L-threonine deaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THRD_L"]}, "metabolites": {"thr__L_c": -1.0, "2obut_c": 1.0, "nh4_c": 1.0}, "id": "THRD_L", "gene_reaction_rule": "YCL064C or YKL218C"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "L threonine deaminase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THRD_Lm"]}, "metabolites": {"nh4_m": 1.0, "thr__L_m": -1.0, "2obut_m": 1.0}, "id": "THRD_Lm", "gene_reaction_rule": "YER086W"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "Threonine synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THRS"]}, "metabolites": {"phom_c": -1.0, "thr__L_c": 1.0, "pi_c": 1.0, "h2o_c": -1.0}, "id": "THRS", "gene_reaction_rule": "YCR053W"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "Threonyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THRTRS"]}, "metabolites": {"atp_c": -1.0, "thrtrna_c": 1.0, "ppi_c": 1.0, "amp_c": 1.0, "thr__L_c": -1.0, "trnathr_c": -1.0}, "id": "THRTRS", "gene_reaction_rule": "YIL078W"}, {"subsystem": "Threonine and Lysine Metabolism", "name": "Threonyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THRTRSm"]}, "metabolites": {"ppi_m": 1.0, "thrtrna_m": 1.0, "atp_m": -1.0, "trnathr_m": -1.0, "thr__L_m": -1.0, "amp_m": 1.0}, "id": "THRTRSm", "gene_reaction_rule": "YKL194C"}, {"subsystem": "Transport, Mitochondrial", "name": "Threonine mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["THRt2m"]}, "metabolites": {"thr__L_c": -1.0, "h_m": 1.0, "thr__L_m": 1.0, "h_c": -1.0}, "id": "THRt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L threonine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["THRt2r"]}, "metabolites": {"thr__L_c": 1.0, "h_e": -1.0, "thr__L_e": -1.0, "h_c": 1.0}, "id": "THRt2r", "gene_reaction_rule": "YCL025C or YBR069C or YKR039W or YDR508C"}, {"subsystem": "Transport, Extracellular", "name": "Thymine reversible transport via proton antiport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["THYMt3r"]}, "metabolites": {"thym_e": 1.0, "h_e": -1.0, "h_c": 1.0, "thym_c": -1.0}, "id": "THYMt3r", "gene_reaction_rule": ""}, {"subsystem": "Thiamine Metabolism", "name": "Thiazole phosphate synthesis xylulose 5 phosphate yeast specific", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THZPSN1_SC"]}, "metabolites": {"cys__L_c": -1.0, "h2o_c": 3.0, "4abut_c": 1.0, "4mpetz_c": 1.0, "pyr_c": 1.0, "xu5p__D_c": -1.0, "nh4_c": 1.0, "achms_c": -1.0, "ac_c": 1.0, "co2_c": 1.0, "gly_c": -1.0, "h_c": -1.0}, "id": "THZPSN1_SC", "gene_reaction_rule": ""}, {"subsystem": "Thiamine Metabolism", "name": "Thiazole phosphate synthesis ribose 5 phosphate yeast specifc", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["THZPSN2_SC"]}, "metabolites": {"cys__L_c": -1.0, "h2o_c": 3.0, "ac_c": 1.0, "4abut_c": 1.0, "4mpetz_c": 1.0, "pyr_c": 1.0, "nh4_c": 1.0, "achms_c": -1.0, "r5p_c": -1.0, "co2_c": 1.0, "gly_c": -1.0, "h_c": -1.0}, "id": "THZPSN2_SC", "gene_reaction_rule": ""}, {"subsystem": "Pentose Phosphate Pathway", "name": "Transketolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TKT1"]}, "metabolites": {"r5p_c": -1.0, "xu5p__D_c": -1.0, "s7p_c": 1.0, "g3p_c": 1.0}, "id": "TKT1", "gene_reaction_rule": "YBR117C or YPR074C"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Transketolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TKT2"]}, "metabolites": {"e4p_c": -1.0, "xu5p__D_c": -1.0, "g3p_c": 1.0, "f6p_c": 1.0}, "id": "TKT2", "gene_reaction_rule": "YPR074C or YBR117C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Thymidine kinase (ATP:thymidine)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TMDK1"]}, "metabolites": {"thymd_c": -1.0, "dtmp_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "TMDK1", "gene_reaction_rule": ""}, {"subsystem": "Thiamine Metabolism", "name": "Thiamine diphosphokinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TMDPK"]}, "metabolites": {"thmpp_c": 1.0, "thm_c": -1.0, "amp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "TMDPK", "gene_reaction_rule": "YOR143C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Thymidine phosphorylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TMDPP"]}, "metabolites": {"2dr1p_c": 1.0, "pi_c": -1.0, "thym_c": 1.0, "thymd_c": -1.0}, "id": "TMDPP", "gene_reaction_rule": "YLR209C"}, {"subsystem": "Thiamine Metabolism", "name": "Thiamine diphosphate kinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TMDPPK"]}, "metabolites": {"thmpp_c": -1.0, "thmtp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "TMDPPK", "gene_reaction_rule": "YOR143C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Thymidylate synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TMDS"]}, "metabolites": {"dtmp_c": 1.0, "dump_c": -1.0, "mlthf_c": -1.0, "dhf_c": 1.0}, "id": "TMDS", "gene_reaction_rule": "YOR074C"}, {"subsystem": "Thiamine Metabolism", "name": "Thiaminase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TMN"]}, "metabolites": {"4mhetz_c": 1.0, "thm_c": -1.0, "h_c": 1.0, "h2o_c": -1.0, "4ahmmp_c": 1.0}, "id": "TMN", "gene_reaction_rule": ""}, {"subsystem": "Thiamine Metabolism", "name": "Thiamine-phosphate kinase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TMPKr"]}, "metabolites": {"thmpp_c": 1.0, "atp_c": -1.0, "adp_c": 1.0, "thmmp_c": -1.0}, "id": "TMPK", "gene_reaction_rule": ""}, {"subsystem": "Thiamine Metabolism", "name": "Thiamine-phosphate diphosphorylase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TMPPP"]}, "metabolites": {"4mpetz_c": -1.0, "ppi_c": 1.0, "thmmp_c": 1.0, "2mahmp_c": -1.0, "h_c": -1.0}, "id": "TMPPP", "gene_reaction_rule": "YPL214C"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Triose-phosphate isomerase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TPI"]}, "metabolites": {"dhap_c": -1.0, "g3p_c": 1.0}, "id": "TPI", "gene_reaction_rule": "YDR050C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Thioredoxin reductase (NADPH)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TRDR"]}, "metabolites": {"trdox_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "trdrd_c": 1.0}, "id": "TRDR", "gene_reaction_rule": "YDR353W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Thioredoxin reductase NADPH ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TRDRm"]}, "metabolites": {"nadph_m": -1.0, "h_m": -1.0, "trdox_m": -1.0, "nadp_m": 1.0, "trdrd_m": 1.0}, "id": "TRDRm", "gene_reaction_rule": "YHR106W"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Trehalose-phosphatase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TRE6PP"]}, "metabolites": {"tre_c": 1.0, "tre6p_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0}, "id": "TRE6PP", "gene_reaction_rule": "(YDR074W and YBR126C and YML100W) or (YMR261C and YDR074W and YBR126C)"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Alpha,alpha-trehalose-phosphate synthase (UDP-forming)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TRE6PS"]}, "metabolites": {"tre6p_c": 1.0, "g6p_c": -1.0, "udpg_c": -1.0, "udp_c": 1.0, "h_c": 1.0}, "id": "TRE6PS", "gene_reaction_rule": "(YDR074W and YBR126C and YML100W) or (YMR261C and YDR074W and YBR126C)"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Alpha,alpha-trehalase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TREH"]}, "metabolites": {"tre_c": -1.0, "glc__D_c": 2.0, "h2o_c": -1.0}, "id": "TREH", "gene_reaction_rule": "YBR001C or YDR001C"}, {"subsystem": "Alternate Carbon Metabolism", "name": "Alpha alpha trehalase vacuolar ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TREHv"]}, "metabolites": {"glc__D_v": 2.0, "tre_v": -1.0, "h2o_v": -1.0}, "id": "TREHv", "gene_reaction_rule": "YPR026W"}, {"subsystem": "Transport, Extracellular", "name": "Trehalose transport in via proton symporter", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TREt2"]}, "metabolites": {"tre_c": 1.0, "h_e": -1.0, "h_c": 1.0, "tre_e": -1.0}, "id": "TREt2", "gene_reaction_rule": ""}, {"subsystem": "Transport, Vacuolar", "name": "Trehalose vacuolar transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TREt2v"]}, "metabolites": {"tre_c": -1.0, "h_v": 1.0, "h_c": -1.0, "tre_v": 1.0}, "id": "TREt2v", "gene_reaction_rule": ""}, {"subsystem": "Glycerolipid Metabolism", "name": "Triglycerol synthesis", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TRIGS_SC"]}, "metabolites": {"hdcoa_c": -0.17, "odecoa_c": -0.24, "12dgr_SC_c": -0.01, "ddcacoa_c": -0.06, "pmtcoa_c": -0.27, "stcoa_c": -0.05, "coa_c": 1.0, "triglyc_SC_c": 0.01, "ocdycacoa_c": -0.09, "dcacoa_c": -0.02, "tdcoa_c": -0.1}, "id": "TRIGS_SC", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "L Tryptophanoxygen 2 3 oxidoreductase decyclizing ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TRPO2"]}, "metabolites": {"Lfmkynr_c": 1.0, "o2_c": -1.0, "trp__L_c": -1.0}, "id": "TRPO2", "gene_reaction_rule": "YJR078W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Tryptophan synthase (indoleglycerol phosphate)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TRPS1"]}, "metabolites": {"h2o_c": 1.0, "ser__L_c": -1.0, "g3p_c": 1.0, "trp__L_c": 1.0, "3ig3p_c": -1.0}, "id": "TRPS1", "gene_reaction_rule": "YGL026C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Tryptophanyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TRPTRS"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "trnatrp_c": -1.0, "amp_c": 1.0, "trptrna_c": 1.0, "trp__L_c": -1.0}, "id": "TRPTRS", "gene_reaction_rule": "YOL097C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Tryptophanyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TRPTRSm"]}, "metabolites": {"trnatrp_m": -1.0, "ppi_m": 1.0, "atp_m": -1.0, "trp__L_m": -1.0, "trptrna_m": 1.0, "amp_m": 1.0}, "id": "TRPTRSm", "gene_reaction_rule": "YDR268W"}, {"subsystem": "Transport, Mitochondrial", "name": "Tryptophan mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TRPt2m"]}, "metabolites": {"trp__L_m": 1.0, "h_m": 1.0, "h_c": -1.0, "trp__L_c": -1.0}, "id": "TRPt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L tryptophan reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TRPt2r"]}, "metabolites": {"trp__L_e": -1.0, "h_e": -1.0, "h_c": 1.0, "trp__L_c": 1.0}, "id": "TRPt2r", "gene_reaction_rule": "YOL020W or YKR039W or YBR069C or YBR068C or YDR046C"}, {"subsystem": "Transport, Extracellular", "name": "Fatty acid transport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TTDCAt"]}, "metabolites": {"ttdca_e": -1.0, "ttdca_c": 1.0}, "id": "TTDCAtr", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Tyrosine transaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TYRTA"]}, "metabolites": {"akg_c": -1.0, "34hpp_c": 1.0, "glu__L_c": 1.0, "tyr__L_c": -1.0}, "id": "TYRTA", "gene_reaction_rule": "YLR027C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Tyrosine transaminase irreversible", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TYRTAi"]}, "metabolites": {"akg_c": 1.0, "glu__L_c": -1.0, "34hpp_c": -1.0, "tyr__L_c": 1.0}, "id": "TYRTAi", "gene_reaction_rule": "YHR137W or YGL202W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "TYRTAm", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TYRTAm"]}, "metabolites": {"glu__L_m": 1.0, "tyr__L_m": -1.0, "34hpp_m": 1.0, "akg_m": -1.0}, "id": "TYRTAm", "gene_reaction_rule": "YKL106W"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "TYRTAp", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TYRTAp"]}, "metabolites": {"glu__L_x": 1.0, "akg_x": -1.0, "tyr__L_x": -1.0, "34hpp_x": 1.0}, "id": "TYRTAp", "gene_reaction_rule": "YLR027C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Tyrosyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TYRTRS"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "tyrtrna_c": 1.0, "trnatyr_c": -1.0, "amp_c": 1.0, "tyr__L_c": -1.0}, "id": "TYRTRS", "gene_reaction_rule": "YGR185C"}, {"subsystem": "Tyrosine, Tryptophan, and Phenylalanine Metabolism", "name": "Tyrosyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["TYRTRSm"]}, "metabolites": {"ppi_m": 1.0, "tyrtrna_m": 1.0, "atp_m": -1.0, "tyr__L_m": -1.0, "amp_m": 1.0, "trnatyr_m": -1.0}, "id": "TYRTRSm", "gene_reaction_rule": "YPL097W"}, {"subsystem": "Transport, Mitochondrial", "name": "Tyrosine mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TYRt2m"]}, "metabolites": {"tyr__L_m": 1.0, "h_m": 1.0, "h_c": -1.0, "tyr__L_c": -1.0}, "id": "TYRt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Peroxisomal", "name": "Tyrosine peroxisomal transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TYRt2p"]}, "metabolites": {"tyr__L_x": 1.0, "h_c": -1.0, "h_x": 1.0, "tyr__L_c": -1.0}, "id": "TYRt2p", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L tyrosine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["TYRt2r"]}, "metabolites": {"tyr__L_e": -1.0, "h_e": -1.0, "h_c": 1.0, "tyr__L_c": 1.0}, "id": "TYRt2r", "gene_reaction_rule": "YBR068C or YDR046C or YBR069C or YOL020W or YCL025C or YKR039W"}, {"subsystem": "Glutamate metabolism", "name": "UDP N acetylglucosamine diphosphorylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["UDPACGLP"]}, "metabolites": {"ppi_c": 1.0, "utp_c": -1.0, "udpacgal_c": 1.0, "h_c": -1.0, "acgam1p_c": -1.0}, "id": "UDPACGLP", "gene_reaction_rule": "YDL103C"}, {"subsystem": "Galactose metabolism", "name": "UDPglucose 4-epimerase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["UDPG4E"]}, "metabolites": {"udpgal_c": 1.0, "udpg_c": -1.0}, "id": "UDPG4E", "gene_reaction_rule": "YBR019C"}, {"subsystem": "Galactose metabolism", "name": "UDPglucose--hexose-1-phosphate uridylyltransferase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["UGLT"]}, "metabolites": {"udpgal_c": 1.0, "udpg_c": -1.0, "gal1p_c": -1.0, "g1p_c": 1.0}, "id": "UGLT", "gene_reaction_rule": "YBR018C"}, {"subsystem": "Histidine Metabolism", "name": "Ureidoglycolate hydrolase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["UGLYCHr"]}, "metabolites": {"urdglyc_c": -1.0, "h2o_c": -1.0, "glx_c": 1.0, "h_c": -2.0, "co2_c": 1.0, "nh4_c": 2.0}, "id": "UGLYCH", "gene_reaction_rule": "YIR032C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "UMP kinase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["UMPK"]}, "metabolites": {"ump_c": -1.0, "udp_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "UMPK", "gene_reaction_rule": "YKL024C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "UMP kinase nuclear", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["UMPKn"]}, "metabolites": {"adp_n": 1.0, "ump_n": -1.0, "atp_n": -1.0, "udp_n": 1.0}, "id": "UMPKn", "gene_reaction_rule": "YKL024C"}, {"subsystem": "Transport, Nuclear", "name": "UMP nuclear transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["UMPtn"]}, "metabolites": {"ump_c": -1.0, "ump_n": 1.0}, "id": "UMPtn", "gene_reaction_rule": ""}, {"subsystem": "Porphyrin and Chlorophyll Metabolism", "name": "Uroporphyrinogen methyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["UPP3MT"]}, "metabolites": {"amet_c": -2.0, "dscl_c": 1.0, "ahcys_c": 2.0, "h_c": 1.0, "uppg3_c": -1.0}, "id": "UPP3MT", "gene_reaction_rule": "YKR069W"}, {"subsystem": "Porphyrin and Chlorophyll Metabolism", "name": "Uroporphyrinogen-III synthase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["UPP3S"]}, "metabolites": {"h2o_c": 1.0, "hmbil_c": -1.0, "uppg3_c": 1.0}, "id": "UPP3S", "gene_reaction_rule": "YOR278W"}, {"subsystem": "Porphyrin and Chlorophyll Metabolism", "name": "Uroporphyrinogen decarboxylase (uroporphyrinogen III)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["UPPDC1"]}, "metabolites": {"co2_c": 4.0, "h_c": -4.0, "uppg3_c": -1.0, "cpppg3_c": 1.0}, "id": "UPPDC1", "gene_reaction_rule": "YDR047W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Uracil phosphoribosyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["UPPRT"]}, "metabolites": {"ura_c": -1.0, "ppi_c": 1.0, "prpp_c": -1.0, "ump_c": 1.0}, "id": "UPPRT", "gene_reaction_rule": "YHR128W"}, {"subsystem": "Transport, Extracellular", "name": "Uracil transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["URAt2"]}, "metabolites": {"ura_c": 1.0, "h_e": -1.0, "h_c": 1.0, "ura_e": -1.0}, "id": "URAt2", "gene_reaction_rule": "YBR021W"}, {"subsystem": "Transport, Extracellular", "name": "Urea reversible transport via proton symport 2 H ", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["UREA2t2"]}, "metabolites": {"urea_c": 1.0, "h_e": -2.0, "urea_e": -1.0, "h_c": 2.0}, "id": "UREA2t2", "gene_reaction_rule": "YHL016C"}, {"subsystem": "Nitrogen Metabolism", "name": "Urea carboxylase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["UREASE"]}, "metabolites": {"urea_c": -1.0, "atp_c": -1.0, "hco3_c": -1.0, "allphn_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "UREASE", "gene_reaction_rule": "YBR208C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Uridylate kinase (dUMP)", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["URIDK2r"]}, "metabolites": {"dump_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "dudp_c": 1.0}, "id": "URIDK2r", "gene_reaction_rule": "YKL024C"}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Uridylate kinase dUMP nuclear", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["URIDK2rn"]}, "metabolites": {"dudp_n": 1.0, "dump_n": -1.0, "adp_n": 1.0, "atp_n": -1.0}, "id": "URIDK2rn", "gene_reaction_rule": "YKL024C"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Uridine kinase ATPUridine ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["URIK1"]}, "metabolites": {"ump_c": 1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "uri_c": -1.0}, "id": "URIK1", "gene_reaction_rule": "YNR012W"}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "Uridine kinase (GTP:Uridine)", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["URIK2"]}, "metabolites": {"uri_c": -1.0, "gtp_c": -1.0, "h_c": 1.0, "ump_c": 1.0, "gdp_c": 1.0}, "id": "URIK2", "gene_reaction_rule": "YNR012W"}, {"subsystem": "Transport, Extracellular", "name": "Uridine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["URIt2"]}, "metabolites": {"uri_c": 1.0, "h_e": -1.0, "h_c": 1.0, "uri_e": -1.0}, "id": "URIt2", "gene_reaction_rule": "YBL042C"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Valine transaminase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["VALTA"]}, "metabolites": {"akg_c": -1.0, "glu__L_c": 1.0, "3mob_c": 1.0, "val__L_c": -1.0}, "id": "VALTA", "gene_reaction_rule": "YJR148W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Valyl-tRNA synthetase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["VALTRS"]}, "metabolites": {"valtrna_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "trnaval_c": -1.0, "val__L_c": -1.0}, "id": "VALTRS", "gene_reaction_rule": "YGR094W"}, {"subsystem": "Valine, Leucine, and Isoleucine Metabolism", "name": "Valyl tRNA synthetase mitochondrial", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["VALTRSm"]}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "valtrna_m": 1.0, "val__L_m": -1.0, "trnaval_m": -1.0, "amp_m": 1.0}, "id": "VALTRSm", "gene_reaction_rule": "YGR094W"}, {"subsystem": "Transport, Mitochondrial", "name": "Valine reversible mitochondrial transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["VALt2m"]}, "metabolites": {"val__L_m": 1.0, "h_m": 1.0, "h_c": -1.0, "val__L_c": -1.0}, "id": "VALt2m", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "L valine reversible transport via proton symport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["VALt2r"]}, "metabolites": {"val__L_e": -1.0, "h_e": -1.0, "h_c": 1.0, "val__L_c": 1.0}, "id": "VALt2r", "gene_reaction_rule": "YDR046C or YCL025C or YKR039W or YBR069C or YBR068C"}, {"subsystem": "Transport, Extracellular", "name": "Xanthine reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["XANt"]}, "metabolites": {"xan_e": -1.0, "xan_c": 1.0}, "id": "XANt", "gene_reaction_rule": ""}, {"subsystem": "Nucleotide Salvage Pathway", "name": "Xanthine phosphoribosyltransferase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["XPPT"]}, "metabolites": {"xmp_c": 1.0, "ppi_c": 1.0, "xan_c": -1.0, "prpp_c": -1.0}, "id": "XPPT", "gene_reaction_rule": "YJR133W"}, {"subsystem": "Transport, Extracellular", "name": "Xanthosine transport in via proton symport", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["XTSNt2"]}, "metabolites": {"xtsn_e": -1.0, "h_e": -1.0, "h_c": 1.0, "xtsn_c": 1.0}, "id": "XTSNt2", "gene_reaction_rule": ""}, {"subsystem": "Xylose Metabolism", "name": "Xylulokinase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["XYLK"]}, "metabolites": {"xylu__D_c": -1.0, "xu5p__D_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "XYLK", "gene_reaction_rule": "YGR194C"}, {"subsystem": "Xylose Metabolism", "name": "Xylose reductase", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["XYLR"]}, "metabolites": {"xylt_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "xyl__D_c": -1.0}, "id": "XYLR", "gene_reaction_rule": "YHR104W"}, {"subsystem": "Xylose Metabolism", "name": "Xylitol dehydrogenase D xyulose forming ", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["XYLTD_D"]}, "metabolites": {"xylu__D_c": 1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "xylt_c": -1.0}, "id": "XYLTD_D", "gene_reaction_rule": "YLR070C"}, {"subsystem": "Transport, Extracellular", "name": "Xylitol transport via passive diffusion", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["XYLTt"]}, "metabolites": {"xylt_c": 1.0, "xylt_e": -1.0}, "id": "XYLTt", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "D xylose reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["XYLt"]}, "metabolites": {"xyl__D_e": -1.0, "xyl__D_c": 1.0}, "id": "XYLt", "gene_reaction_rule": ""}, {"subsystem": "Purine and Pyrimidine Biosynthesis", "name": "YUMP synthetase", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["YUMPS"]}, "metabolites": {"ura_c": -1.0, "h2o_c": 1.0, "psd5p_c": 1.0, "r5p_c": -1.0}, "id": "YUMPS", "gene_reaction_rule": "YGL063W or YPL212C or YFL001W or YNL292W"}, {"subsystem": "Transport, Extracellular", "name": "Zymosterol reversible transport", "upper_bound": 999999.0, "lower_bound": -999999.0, "notes": {"original_bigg_ids": ["ZYMSTt"]}, "metabolites": {"zymst_e": -1.0, "zymst_c": 1.0}, "id": "ZYMSTt", "gene_reaction_rule": "YOR011W"}, {"subsystem": "Biomass and maintenance functions", "name": "Biomass SC4 bal", "upper_bound": 999999.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["biomass_SC4_bal"]}, "metabolites": {"cys__L_c": -0.0066, "h2o_c": -59.276, "glycogen_c": -0.5185, "ile__L_c": -0.1927, "glu__L_c": -0.3018, "dgmp_c": -0.0024, "tre_c": -0.0234, "arg__L_c": -0.1607, "h_c": 58.7162, "ptd1ino_SC_c": -5.3e-05, "zymst_c": -0.0015, "trp__L_c": -0.0284, "val__L_c": -0.2646, "ump_c": -0.0599, "dtmp_c": -0.0036, "atp_c": -59.276, "cmp_c": -0.0447, "mannan_c": -0.8079, "pro__L_c": -0.1647, "13BDglcn_c": -1.1348, "so4_c": -0.02, "ser__L_c": -0.1854, "adp_c": 59.276, "pe_SC_c": -4.5e-05, "thr__L_c": -0.1914, "gly_c": -0.2904, "leu__L_c": -0.2964, "gmp_c": -0.046, "lys__L_c": -0.2862, "phe__L_c": -0.1339, "dcmp_c": -0.0024, "ala__L_c": -0.4588, "amp_c": -0.046, "met__L_c": -0.0507, "tyr__L_c": -0.102, "damp_c": -0.0036, "gln__L_c": -0.1054, "pa_SC_c": -6e-06, "asp__L_c": -0.2975, "ps_SC_c": -1.7e-05, "asn__L_c": -0.1017, "his__L_c": -0.0663, "triglyc_SC_c": -6.6e-05, "pc_SC_c": -6e-05, "pi_c": 59.305, "ergst_c": -0.0007}, "objective_coefficient": 1.0, "id": "BIOMASS_SC4_bal", "gene_reaction_rule": ""}], "genes": [{"notes": {"original_bigg_ids": ["YPL231W"]}, "name": "FAS2", "id": "YPL231W"}, {"notes": {"original_bigg_ids": ["YKL182W"]}, "name": "FAS1", "id": "YKL182W"}, {"notes": {"original_bigg_ids": ["YPL147W"]}, "name": "PXA1", "id": "YPL147W"}, {"notes": {"original_bigg_ids": ["YKL188C"]}, "name": "PXA2", "id": "YKL188C"}, {"notes": {"original_bigg_ids": ["YPL117C"]}, "name": "IDI1", "id": "YPL117C"}, {"notes": {"original_bigg_ids": ["YEL058W"]}, "name": "PCM1", "id": "YEL058W"}, {"notes": {"original_bigg_ids": ["YER069W"]}, "name": "ARG5,6", "id": "YER069W"}, {"notes": {"original_bigg_ids": ["YJL071W"]}, "name": "ARG2", "id": "YJL071W"}, {"notes": {"original_bigg_ids": ["YMR062C"]}, "name": "ARG7", "id": "YMR062C"}, {"notes": {"original_bigg_ids": ["YCL009C"]}, "name": "ILV6", "id": "YCL009C"}, {"notes": {"original_bigg_ids": ["YMR108W"]}, "name": "ILV2", "id": "YMR108W"}, {"notes": {"original_bigg_ids": ["YBL015W"]}, "name": "ACH1", "id": "YBL015W"}, {"notes": {"original_bigg_ids": ["YGL205W"]}, "name": "POX1", "id": "YGL205W"}, {"notes": {"original_bigg_ids": ["YER061C"]}, "name": "CEM1", "id": "YER061C"}, {"notes": {"original_bigg_ids": ["YLR304C"]}, "name": "ACO1", "id": "YLR304C"}, {"notes": {"original_bigg_ids": ["YJL200C"]}, "name": "ACO2", "id": "YJL200C"}, {"notes": {"original_bigg_ids": ["YOL140W"]}, "name": "ARG8", "id": "YOL140W"}, {"notes": {"original_bigg_ids": ["YAR071W"]}, "name": "PHO11", "id": "YAR071W"}, {"notes": {"original_bigg_ids": ["YPL148C"]}, "name": "PPT2", "id": "YPL148C"}, {"notes": {"original_bigg_ids": ["YLR153C"]}, "name": "ACS2", "id": "YLR153C"}, {"notes": {"original_bigg_ids": ["YAL054C"]}, "name": "ACS1", "id": "YAL054C"}, {"notes": {"original_bigg_ids": ["YCR032W"]}, "name": "BPH1", "id": "YCR032W"}, {"notes": {"original_bigg_ids": ["YNL141W"]}, "name": "AAH1", "id": "YNL141W"}, {"notes": {"original_bigg_ids": ["YNR033W"]}, "name": "ABZ1", "id": "YNR033W"}, {"notes": {"original_bigg_ids": ["YGL186C"]}, "name": "TPN1", "id": "YGL186C"}, {"notes": {"original_bigg_ids": ["YER056C"]}, "name": "FCY2", "id": "YER056C"}, {"notes": {"original_bigg_ids": ["YER060W"]}, "name": "FCY21", "id": "YER060W"}, {"notes": {"original_bigg_ids": ["YDR226W"]}, "name": "ADK1", "id": "YDR226W"}, {"notes": {"original_bigg_ids": ["YER170W"]}, "name": "ADK2", "id": "YER170W"}, {"notes": {"original_bigg_ids": ["YOL052C"]}, "name": "SPE2", "id": "YOL052C"}, {"notes": {"original_bigg_ids": ["YJL005W"]}, "name": "CYR1", "id": "YJL005W"}, {"notes": {"original_bigg_ids": ["YJR105W"]}, "name": "ADO1", "id": "YJR105W"}, {"notes": {"original_bigg_ids": ["YDR400W"]}, "name": "URH1", "id": "YDR400W"}, {"notes": {"original_bigg_ids": ["YDR441C"]}, "name": "APT2", "id": "YDR441C"}, {"notes": {"original_bigg_ids": ["YML022W"]}, "name": "APT1", "id": "YML022W"}, {"notes": {"original_bigg_ids": ["YKL001C"]}, "name": "MET14", "id": "YKL001C"}, {"notes": {"original_bigg_ids": ["YLR359W"]}, "name": "ADE13", "id": "YLR359W"}, {"notes": {"original_bigg_ids": ["YNL220W"]}, "name": "ADE12", "id": "YNL220W"}, {"notes": {"original_bigg_ids": ["YER055C"]}, "name": "HIS1", "id": "YER055C"}, {"notes": {"original_bigg_ids": ["YML035C"]}, "name": "AMD1", "id": "YML035C"}, {"notes": {"original_bigg_ids": ["YJL070C"]}, "name": "None", "id": "YJL070C"}, {"notes": {"original_bigg_ids": ["YBR284W"]}, "name": "None", "id": "YBR284W"}, {"notes": {"original_bigg_ids": ["YDR354W"]}, "name": "TRP4", "id": "YDR354W"}, {"notes": {"original_bigg_ids": ["YKL211C"]}, "name": "TRP3", "id": "YKL211C"}, {"notes": {"original_bigg_ids": ["YER090W"]}, "name": "TRP2", "id": "YER090W"}, {"notes": {"original_bigg_ids": ["YDR305C"]}, "name": "HNT2", "id": "YDR305C"}, {"notes": {"original_bigg_ids": ["YBR153W"]}, "name": "RIB7", "id": "YBR153W"}, {"notes": {"original_bigg_ids": ["YBR149W"]}, "name": "ARA1", "id": "YBR149W"}, {"notes": {"original_bigg_ids": ["YHR104W"]}, "name": "GRE3", "id": "YHR104W"}, {"notes": {"original_bigg_ids": ["YPL111W"]}, "name": "CAR1", "id": "YPL111W"}, {"notes": {"original_bigg_ids": ["YHR018C"]}, "name": "ARG4", "id": "YHR018C"}, {"notes": {"original_bigg_ids": ["YOL058W"]}, "name": "ARG1", "id": "YOL058W"}, {"notes": {"original_bigg_ids": ["YDR341C"]}, "name": "None", "id": "YDR341C"}, {"notes": {"original_bigg_ids": ["YHR091C"]}, "name": "MSR1", "id": "YHR091C"}, {"notes": {"original_bigg_ids": ["YKR039W"]}, "name": "GAP1", "id": "YKR039W"}, {"notes": {"original_bigg_ids": ["YNL270C"]}, "name": "ALP1", "id": "YNL270C"}, {"notes": {"original_bigg_ids": ["YEL063C"]}, "name": "CAN1", "id": "YEL063C"}, {"notes": {"original_bigg_ids": ["YBR034C"]}, "name": "HMT1", "id": "YBR034C"}, {"notes": {"original_bigg_ids": ["YDR158W"]}, "name": "HOM2", "id": "YDR158W"}, {"notes": {"original_bigg_ids": ["YDR321W"]}, "name": "ASP1", "id": "YDR321W"}, {"notes": {"original_bigg_ids": ["YLR157C"]}, "name": "ASP3-2", "id": "YLR157C"}, {"notes": {"original_bigg_ids": ["YLR158C"]}, "name": "ASP3-3", "id": "YLR158C"}, {"notes": {"original_bigg_ids": ["YLR160C"]}, "name": "ASP3-4", "id": "YLR160C"}, {"notes": {"original_bigg_ids": ["YLR155C"]}, "name": "ASP3-1", "id": "YLR155C"}, {"notes": {"original_bigg_ids": ["YML096W"]}, "name": "None", "id": "YML096W"}, {"notes": {"original_bigg_ids": ["YGR124W"]}, "name": "ASN2", "id": "YGR124W"}, {"notes": {"original_bigg_ids": ["YPR145W"]}, "name": "ASN1", "id": "YPR145W"}, {"notes": {"original_bigg_ids": ["YHR019C"]}, "name": "DED81", "id": "YHR019C"}, {"notes": {"original_bigg_ids": ["YCR024C"]}, "name": "SLM5", "id": "YCR024C"}, {"notes": {"original_bigg_ids": ["YPL265W"]}, "name": "DIP5", "id": "YPL265W"}, {"notes": {"original_bigg_ids": ["YCL025C"]}, "name": "AGP1", "id": "YCL025C"}, {"notes": {"original_bigg_ids": ["YDR508C"]}, "name": "GNP1", "id": "YDR508C"}, {"notes": {"original_bigg_ids": ["YJL130C"]}, "name": "URA2", "id": "YJL130C"}, {"notes": {"original_bigg_ids": ["YER052C"]}, "name": "HOM3", "id": "YER052C"}, {"notes": {"original_bigg_ids": ["YLR027C"]}, "name": "AAT2", "id": "YLR027C"}, {"notes": {"original_bigg_ids": ["YKL106W"]}, "name": "AAT1", "id": "YKL106W"}, {"notes": {"original_bigg_ids": ["YLL018C"]}, "name": "DPS1", "id": "YLL018C"}, {"notes": {"original_bigg_ids": ["YPL104W"]}, "name": "MSD1", "id": "YPL104W"}, {"notes": {"original_bigg_ids": ["YFL055W"]}, "name": "AGP3", "id": "YFL055W"}, {"notes": {"original_bigg_ids": ["YPR128C"]}, "name": "ANT1", "id": "YPR128C"}, {"notes": {"original_bigg_ids": ["YDR530C"]}, "name": "APA2", "id": "YDR530C"}, {"notes": {"original_bigg_ids": ["YCL050C"]}, "name": "APA1", "id": "YCL050C"}, {"notes": {"original_bigg_ids": ["YGR282C"]}, "name": "BGL2", "id": "YGR282C"}, {"notes": {"original_bigg_ids": ["YOR190W"]}, "name": "SPR1", "id": "YOR190W"}, {"notes": {"original_bigg_ids": ["YLR300W"]}, "name": "EXG1", "id": "YLR300W"}, {"notes": {"original_bigg_ids": ["YDR261C"]}, "name": "EXG2", "id": "YDR261C"}, {"notes": {"original_bigg_ids": ["YCR034W"]}, "name": "ELO2", "id": "YCR034W"}, {"notes": {"original_bigg_ids": ["YGR032W"]}, "name": "GSC2", "id": "YGR032W"}, {"notes": {"original_bigg_ids": ["YLR342W"]}, "name": "FKS1", "id": "YLR342W"}, {"notes": {"original_bigg_ids": ["YMR306W"]}, "name": "FKS3", "id": "YMR306W"}, {"notes": {"original_bigg_ids": ["YBR265W"]}, "name": "TSC10", "id": "YBR265W"}, {"notes": {"original_bigg_ids": ["YJR025C"]}, "name": "BNA1", "id": "YJR025C"}, {"notes": {"original_bigg_ids": ["YHR037W"]}, "name": "PUT2", "id": "YHR037W"}, {"notes": {"original_bigg_ids": ["YCR053W"]}, "name": "THR4", "id": "YCR053W"}, {"notes": {"original_bigg_ids": ["YDL210W"]}, "name": "UGA4", "id": "YDL210W"}, {"notes": {"original_bigg_ids": ["YBR115C"]}, "name": "LYS2", "id": "YBR115C"}, {"notes": {"original_bigg_ids": ["YGL154C"]}, "name": "LYS5", "id": "YGL154C"}, {"notes": {"original_bigg_ids": ["YGR019W"]}, "name": "UGA1", "id": "YGR019W"}, {"notes": {"original_bigg_ids": ["YOR374W"]}, "name": "ALD4", "id": "YOR374W"}, {"notes": {"original_bigg_ids": ["YER073W"]}, "name": "ALD5", "id": "YER073W"}, {"notes": {"original_bigg_ids": ["YOR348C"]}, "name": "PUT4", "id": "YOR348C"}, {"notes": {"original_bigg_ids": ["YPL028W"]}, "name": "ERG10", "id": "YPL028W"}, {"notes": {"original_bigg_ids": ["YIL160C"]}, "name": "POT1", "id": "YIL160C"}, {"notes": {"original_bigg_ids": ["YNR016C"]}, "name": "ACC1", "id": "YNR016C"}, {"notes": {"original_bigg_ids": ["YFL017C"]}, "name": "GNA1", "id": "YFL017C"}, {"notes": {"original_bigg_ids": ["YDL052C"]}, "name": "SLC1", "id": "YDL052C"}, {"notes": {"original_bigg_ids": ["YFL030W"]}, "name": "AGX1", "id": "YFL030W"}, {"notes": {"original_bigg_ids": ["YER043C"]}, "name": "SAH1", "id": "YER043C"}, {"notes": {"original_bigg_ids": ["YLR303W"]}, "name": "MET17", "id": "YLR303W"}, {"notes": {"original_bigg_ids": ["YMR120C"]}, "name": "ADE17", "id": "YMR120C"}, {"notes": {"original_bigg_ids": ["YLR028C"]}, "name": "ADE16", "id": "YLR028C"}, {"notes": {"original_bigg_ids": ["YOR128C"]}, "name": "ADE2", "id": "YOR128C"}, {"notes": {"original_bigg_ids": ["YDR148C"]}, "name": "KGD2", "id": "YDR148C"}, {"notes": {"original_bigg_ids": ["YIL125W"]}, "name": "KGD1", "id": "YIL125W"}, {"notes": {"original_bigg_ids": ["YFL018C"]}, "name": "LPD1", "id": "YFL018C"}, {"notes": {"original_bigg_ids": ["YDR481C"]}, "name": "PHO8", "id": "YDR481C"}, {"notes": {"original_bigg_ids": ["YDR232W"]}, "name": "HEM1", "id": "YDR232W"}, {"notes": {"original_bigg_ids": ["YDR111C"]}, "name": "ALT2", "id": "YDR111C"}, {"notes": {"original_bigg_ids": ["YLR089C"]}, "name": "ALT1", "id": "YLR089C"}, {"notes": {"original_bigg_ids": ["YOR335C"]}, "name": "ALA1", "id": "YOR335C"}, {"notes": {"original_bigg_ids": ["YOL020W"]}, "name": "TAT2", "id": "YOL020W"}, {"notes": {"original_bigg_ids": ["YMR083W"]}, "name": "ADH3", "id": "YMR083W"}, {"notes": {"original_bigg_ids": ["YMR303C"]}, "name": "ADH2", "id": "YMR303C"}, {"notes": {"original_bigg_ids": ["YDL168W"]}, "name": "SFA1", "id": "YDL168W"}, {"notes": {"original_bigg_ids": ["YOL086C"]}, "name": "ADH1", "id": "YOL086C"}, {"notes": {"original_bigg_ids": ["YGL256W"]}, "name": "ADH4", "id": "YGL256W"}, {"notes": {"original_bigg_ids": ["YBR145W"]}, "name": "ADH5", "id": "YBR145W"}, {"notes": {"original_bigg_ids": ["YMR170C"]}, "name": "ALD2", "id": "YMR170C"}, {"notes": {"original_bigg_ids": ["YMR169C"]}, "name": "ALD3", "id": "YMR169C"}, {"notes": {"original_bigg_ids": ["YPL061W"]}, "name": "ALD6", "id": "YPL061W"}, {"notes": {"original_bigg_ids": ["YIR029W"]}, "name": "DAL2", "id": "YIR029W"}, {"notes": {"original_bigg_ids": ["YIR027C"]}, "name": "DAL1", "id": "YIR027C"}, {"notes": {"original_bigg_ids": ["YIR028W"]}, "name": "DAL4", "id": "YIR028W"}, {"notes": {"original_bigg_ids": ["YJR152W"]}, "name": "DAL5", "id": "YJR152W"}, {"notes": {"original_bigg_ids": ["YBR208C"]}, "name": "DUR1,2", "id": "YBR208C"}, {"notes": {"original_bigg_ids": ["YNR058W"]}, "name": "BIO3", "id": "YNR058W"}, {"notes": {"original_bigg_ids": ["YPL274W"]}, "name": "SAM3", "id": "YPL274W"}, {"notes": {"original_bigg_ids": ["YDR242W"]}, "name": "AMD2", "id": "YDR242W"}, {"notes": {"original_bigg_ids": ["YMR293C"]}, "name": "HER2", "id": "YMR293C"}, {"notes": {"original_bigg_ids": ["YGL008C"]}, "name": "PMA1", "id": "YGL008C"}, {"notes": {"original_bigg_ids": ["YPL036W"]}, "name": "PMA2", "id": "YPL036W"}, {"notes": {"original_bigg_ids": ["YEL027W"]}, "name": "VMA3", "id": "YEL027W"}, {"notes": {"original_bigg_ids": ["YOR332W"]}, "name": "VMA4", "id": "YOR332W"}, {"notes": {"original_bigg_ids": ["YPR036W"]}, "name": "VMA13", "id": "YPR036W"}, {"notes": {"original_bigg_ids": ["YLR447C"]}, "name": "VMA6", "id": "YLR447C"}, {"notes": {"original_bigg_ids": ["YPL234C"]}, "name": "VMA11", "id": "YPL234C"}, {"notes": {"original_bigg_ids": ["YMR054W"]}, "name": "STV1", "id": "YMR054W"}, {"notes": {"original_bigg_ids": ["YGR020C"]}, "name": "VMA7", "id": "YGR020C"}, {"notes": {"original_bigg_ids": ["YBR127C"]}, "name": "VMA2", "id": "YBR127C"}, {"notes": {"original_bigg_ids": ["YEL051W"]}, "name": "VMA8", "id": "YEL051W"}, {"notes": {"original_bigg_ids": ["YDL185W"]}, "name": "VMA1", "id": "YDL185W"}, {"notes": {"original_bigg_ids": ["YHR026W"]}, "name": "VMA16", "id": "YHR026W"}, {"notes": {"original_bigg_ids": ["YKL080W"]}, "name": "VMA5", "id": "YKL080W"}, {"notes": {"original_bigg_ids": ["YDL004W"]}, "name": "ATP16", "id": "YDL004W"}, {"notes": {"original_bigg_ids": ["YBR039W"]}, "name": "ATP3", "id": "YBR039W"}, {"notes": {"original_bigg_ids": ["YPL271W"]}, "name": "ATP15", "id": "YPL271W"}, {"notes": {"original_bigg_ids": ["YDR377W"]}, "name": "ATP17", "id": "YDR377W"}, {"notes": {"original_bigg_ids": ["YDR298C"]}, "name": "ATP5", "id": "YDR298C"}, {"notes": {"original_bigg_ids": ["YPR020W"]}, "name": "ATP20", "id": "YPR020W"}, {"notes": {"original_bigg_ids": ["YBL099W"]}, "name": "ATP1", "id": "YBL099W"}, {"notes": {"original_bigg_ids": ["YJR121W"]}, "name": "ATP2", "id": "YJR121W"}, {"notes": {"original_bigg_ids": ["YDL181W"]}, "name": "INH1", "id": "YDL181W"}, {"notes": {"original_bigg_ids": ["Q0080"]}, "name": "None", "id": "Q0080"}, {"notes": {"original_bigg_ids": ["YKL016C"]}, "name": "ATP7", "id": "YKL016C"}, {"notes": {"original_bigg_ids": ["Q0085"]}, "name": "None", "id": "Q0085"}, {"notes": {"original_bigg_ids": ["YLR295C"]}, "name": "ATP14", "id": "YLR295C"}, {"notes": {"original_bigg_ids": ["YPL078C"]}, "name": "ATP4", "id": "YPL078C"}, {"notes": {"original_bigg_ids": ["Q0130"]}, "name": "None", "id": "Q0130"}, {"notes": {"original_bigg_ids": ["YOR270C"]}, "name": "VPH1", "id": "YOR270C"}, {"notes": {"original_bigg_ids": ["YBL030C"]}, "name": "PET9", "id": "YBL030C"}, {"notes": {"original_bigg_ids": ["YBR085W"]}, "name": "AAC3", "id": "YBR085W"}, {"notes": {"original_bigg_ids": ["YMR056C"]}, "name": "AAC1", "id": "YMR056C"}, {"notes": {"original_bigg_ids": ["YOL064C"]}, "name": "MET22", "id": "YOL064C"}, {"notes": {"original_bigg_ids": ["YGR065C"]}, "name": "VHT1", "id": "YGR065C"}, {"notes": {"original_bigg_ids": ["YNR056C"]}, "name": "BIO5", "id": "YNR056C"}, {"notes": {"original_bigg_ids": ["YGR286C"]}, "name": "BIO2", "id": "YGR286C"}, {"notes": {"original_bigg_ids": ["YNL280C"]}, "name": "ERG24", "id": "YNL280C"}, {"notes": {"original_bigg_ids": ["YMR015C"]}, "name": "ERG5", "id": "YMR015C"}, {"notes": {"original_bigg_ids": ["YGL012W"]}, "name": "ERG4", "id": "YGL012W"}, {"notes": {"original_bigg_ids": ["YGL001C"]}, "name": "ERG26", "id": "YGL001C"}, {"notes": {"original_bigg_ids": ["YLR100W"]}, "name": "ERG27", "id": "YLR100W"}, {"notes": {"original_bigg_ids": ["YGR060W"]}, "name": "ERG25", "id": "YGR060W"}, {"notes": {"original_bigg_ids": ["YLR056W"]}, "name": "ERG3", "id": "YLR056W"}, {"notes": {"original_bigg_ids": ["YMR202W"]}, "name": "ERG2", "id": "YMR202W"}, {"notes": {"original_bigg_ids": ["YGR088W"]}, "name": "CTT1", "id": "YGR088W"}, {"notes": {"original_bigg_ids": ["YDR256C"]}, "name": "CTA1", "id": "YDR256C"}, {"notes": {"original_bigg_ids": ["YJR109C"]}, "name": "CPA2", "id": "YJR109C"}, {"notes": {"original_bigg_ids": ["YOR303W"]}, "name": "CPA1", "id": "YOR303W"}, {"notes": {"original_bigg_ids": ["YCL004W"]}, "name": "PGS1", "id": "YCL004W"}, {"notes": {"original_bigg_ids": ["YDR297W"]}, "name": "SUR2", "id": "YDR297W"}, {"notes": {"original_bigg_ids": ["YMR272C"]}, "name": "SCS7", "id": "YMR272C"}, {"notes": {"original_bigg_ids": ["YGR202C"]}, "name": "PCT1", "id": "YGR202C"}, {"notes": {"original_bigg_ids": ["YGL077C"]}, "name": "HNM1", "id": "YGL077C"}, {"notes": {"original_bigg_ids": ["YLR133W"]}, "name": "CKI1", "id": "YLR133W"}, {"notes": {"original_bigg_ids": ["YPR060C"]}, "name": "ARO7", "id": "YPR060C"}, {"notes": {"original_bigg_ids": ["YGL148W"]}, "name": "ARO2", "id": "YGL148W"}, {"notes": {"original_bigg_ids": ["YLR308W"]}, "name": "CDA2", "id": "YLR308W"}, {"notes": {"original_bigg_ids": ["YLR307W"]}, "name": "CDA1", "id": "YLR307W"}, {"notes": {"original_bigg_ids": ["YBR038W"]}, "name": "CHS2", "id": "YBR038W"}, {"notes": {"original_bigg_ids": ["YBR023C"]}, "name": "CHS3", "id": "YBR023C"}, {"notes": {"original_bigg_ids": ["YNL192W"]}, "name": "CHS1", "id": "YNL192W"}, {"notes": {"original_bigg_ids": ["YBR291C"]}, "name": "CTP1", "id": "YBR291C"}, {"notes": {"original_bigg_ids": ["YDL142C"]}, "name": "CRD1", "id": "YDL142C"}, {"notes": {"original_bigg_ids": ["YDR044W"]}, "name": "HEM13", "id": "YDR044W"}, {"notes": {"original_bigg_ids": ["YOR100C"]}, "name": "CRC1", "id": "YOR100C"}, {"notes": {"original_bigg_ids": ["YBR132C"]}, "name": "AGP2", "id": "YBR132C"}, {"notes": {"original_bigg_ids": ["YAR035W"]}, "name": "YAT1", "id": "YAR035W"}, {"notes": {"original_bigg_ids": ["YML042W"]}, "name": "CAT2", "id": "YML042W"}, {"notes": {"original_bigg_ids": ["YPR062W"]}, "name": "FCY1", "id": "YPR062W"}, {"notes": {"original_bigg_ids": ["YNR001C"]}, "name": "CIT1", "id": "YNR001C"}, {"notes": {"original_bigg_ids": ["YPR001W"]}, "name": "CIT3", "id": "YPR001W"}, {"notes": {"original_bigg_ids": ["YCR005C"]}, "name": "CIT2", "id": "YCR005C"}, {"notes": {"original_bigg_ids": ["YJR103W"]}, "name": "URA8", "id": "YJR103W"}, {"notes": {"original_bigg_ids": ["YBL039C"]}, "name": "URA7", "id": "YBL039C"}, {"notes": {"original_bigg_ids": ["YGL187C"]}, "name": "COX4", "id": "YGL187C"}, {"notes": {"original_bigg_ids": ["Q0275"]}, "name": "None", "id": "Q0275"}, {"notes": {"original_bigg_ids": ["YLR038C"]}, "name": "COX12", "id": "YLR038C"}, {"notes": {"original_bigg_ids": ["YMR256C"]}, "name": "COX7", "id": "YMR256C"}, {"notes": {"original_bigg_ids": ["YIL111W"]}, "name": "COX5B", "id": "YIL111W"}, {"notes": {"original_bigg_ids": ["YGL191W"]}, "name": "COX13", "id": "YGL191W"}, {"notes": {"original_bigg_ids": ["Q0250"]}, "name": "None", "id": "Q0250"}, {"notes": {"original_bigg_ids": ["Q0045"]}, "name": "None", "id": "Q0045"}, {"notes": {"original_bigg_ids": ["YHR051W"]}, "name": "COX6", "id": "YHR051W"}, {"notes": {"original_bigg_ids": ["YDL067C"]}, "name": "COX9", "id": "YDL067C"}, {"notes": {"original_bigg_ids": ["YLR395C"]}, "name": "COX8", "id": "YLR395C"}, {"notes": {"original_bigg_ids": ["YNL052W"]}, "name": "COX5A", "id": "YNL052W"}, {"notes": {"original_bigg_ids": ["YBL045C"]}, "name": "COR1", "id": "YBL045C"}, {"notes": {"original_bigg_ids": ["YJL166W"]}, "name": "QCR8", "id": "YJL166W"}, {"notes": {"original_bigg_ids": ["YOR065W"]}, "name": "CYT1", "id": "YOR065W"}, {"notes": {"original_bigg_ids": ["YEL024W"]}, "name": "RIP1", "id": "YEL024W"}, {"notes": {"original_bigg_ids": ["YFR033C"]}, "name": "QCR6", "id": "YFR033C"}, {"notes": {"original_bigg_ids": ["YGR183C"]}, "name": "QCR9", "id": "YGR183C"}, {"notes": {"original_bigg_ids": ["YPR191W"]}, "name": "QCR2", "id": "YPR191W"}, {"notes": {"original_bigg_ids": ["YDR529C"]}, "name": "QCR7", "id": "YDR529C"}, {"notes": {"original_bigg_ids": ["Q0105"]}, "name": "None", "id": "Q0105"}, {"notes": {"original_bigg_ids": ["YGR012W"]}, "name": "None", "id": "YGR012W"}, {"notes": {"original_bigg_ids": ["YAL012W"]}, "name": "CYS3", "id": "YAL012W"}, {"notes": {"original_bigg_ids": ["YFR055W"]}, "name": "IRC7", "id": "YFR055W"}, {"notes": {"original_bigg_ids": ["YGL184C"]}, "name": "STR3", "id": "YGL184C"}, {"notes": {"original_bigg_ids": ["YNL247W"]}, "name": "None", "id": "YNL247W"}, {"notes": {"original_bigg_ids": ["YGR155W"]}, "name": "CYS4", "id": "YGR155W"}, {"notes": {"original_bigg_ids": ["YDR046C"]}, "name": "BAP3", "id": "YDR046C"}, {"notes": {"original_bigg_ids": ["YBR069C"]}, "name": "TAT1", "id": "YBR069C"}, {"notes": {"original_bigg_ids": ["YBR068C"]}, "name": "BAP2", "id": "YBR068C"}, {"notes": {"original_bigg_ids": ["YLR245C"]}, "name": "CDD1", "id": "YLR245C"}, {"notes": {"original_bigg_ids": ["YNR012W"]}, "name": "URK1", "id": "YNR012W"}, {"notes": {"original_bigg_ids": ["YHR123W"]}, "name": "EPT1", "id": "YHR123W"}, {"notes": {"original_bigg_ids": ["YNL130C"]}, "name": "CPT1", "id": "YNL130C"}, {"notes": {"original_bigg_ids": ["YDR503C"]}, "name": "LPP1", "id": "YDR503C"}, {"notes": {"original_bigg_ids": ["YDR284C"]}, "name": "DPP1", "id": "YDR284C"}, {"notes": {"original_bigg_ids": ["YBR029C"]}, "name": "CDS1", "id": "YBR029C"}, {"notes": {"original_bigg_ids": ["YNR057C"]}, "name": "BIO4", "id": "YNR057C"}, {"notes": {"original_bigg_ids": ["YHR144C"]}, "name": "DCD1", "id": "YHR144C"}, {"notes": {"original_bigg_ids": ["YBR249C"]}, "name": "ARO4", "id": "YBR249C"}, {"notes": {"original_bigg_ids": ["YDR035W"]}, "name": "ARO3", "id": "YDR035W"}, {"notes": {"original_bigg_ids": ["YGL055W"]}, "name": "OLE1", "id": "YGL055W"}, {"notes": {"original_bigg_ids": ["YJL221C"]}, "name": "IMA4", "id": "YJL221C"}, {"notes": {"original_bigg_ids": ["YDR454C"]}, "name": "GUK1", "id": "YDR454C"}, {"notes": {"original_bigg_ids": ["YJR016C"]}, "name": "ILV3", "id": "YJR016C"}, {"notes": {"original_bigg_ids": ["YML070W"]}, "name": "DAK1", "id": "YML070W"}, {"notes": {"original_bigg_ids": ["YFL053W"]}, "name": "DAK2", "id": "YFL053W"}, {"notes": {"original_bigg_ids": ["YOR236W"]}, "name": "DFR1", "id": "YOR236W"}, {"notes": {"original_bigg_ids": ["YNL256W"]}, "name": "FOL1", "id": "YNL256W"}, {"notes": {"original_bigg_ids": ["YKL216W"]}, "name": "URA1", "id": "YKL216W"}, {"notes": {"original_bigg_ids": ["YLR420W"]}, "name": "URA4", "id": "YLR420W"}, {"notes": {"original_bigg_ids": ["YDR127W"]}, "name": "ARO1", "id": "YDR127W"}, {"notes": {"original_bigg_ids": ["YLR348C"]}, "name": "DIC1", "id": "YLR348C"}, {"notes": {"original_bigg_ids": ["YLR172C"]}, "name": "DPH5", "id": "YLR172C"}, {"notes": {"original_bigg_ids": ["YJL167W"]}, "name": "ERG20", "id": "YJL167W"}, {"notes": {"original_bigg_ids": ["YOL096C"]}, "name": "COQ3", "id": "YOL096C"}, {"notes": {"original_bigg_ids": ["YDL100C"]}, "name": "GET3", "id": "YDL100C"}, {"notes": {"original_bigg_ids": ["YMR013C"]}, "name": "SEC59", "id": "YMR013C"}, {"notes": {"original_bigg_ids": ["YAL023C"]}, "name": "PMT2", "id": "YAL023C"}, {"notes": {"original_bigg_ids": ["YDL093W"]}, "name": "PMT5", "id": "YDL093W"}, {"notes": {"original_bigg_ids": ["YOR321W"]}, "name": "PMT3", "id": "YOR321W"}, {"notes": {"original_bigg_ids": ["YGR199W"]}, "name": "PMT6", "id": "YGR199W"}, {"notes": {"original_bigg_ids": ["YDL095W"]}, "name": "PMT1", "id": "YDL095W"}, {"notes": {"original_bigg_ids": ["YJR143C"]}, "name": "PMT4", "id": "YJR143C"}, {"notes": {"original_bigg_ids": ["YPR183W"]}, "name": "DPM1", "id": "YPR183W"}, {"notes": {"original_bigg_ids": ["YKL152C"]}, "name": "GPM1", "id": "YKL152C"}, {"notes": {"original_bigg_ids": ["YNR043W"]}, "name": "MVD1", "id": "YNR043W"}, {"notes": {"original_bigg_ids": ["YHR063C"]}, "name": "PAN5", "id": "YHR063C"}, {"notes": {"original_bigg_ids": ["YLR355C"]}, "name": "ILV5", "id": "YLR355C"}, {"notes": {"original_bigg_ids": ["YCR036W"]}, "name": "RBK1", "id": "YCR036W"}, {"notes": {"original_bigg_ids": ["YJR057W"]}, "name": "CDC8", "id": "YJR057W"}, {"notes": {"original_bigg_ids": ["YLR209C"]}, "name": "PNP1", "id": "YLR209C"}, {"notes": {"original_bigg_ids": ["YBR252W"]}, "name": "DUT1", "id": "YBR252W"}, {"notes": {"original_bigg_ids": ["YHR068W"]}, "name": "DYS1", "id": "YHR068W"}, {"notes": {"original_bigg_ids": ["YDL174C"]}, "name": "DLD1", "id": "YDL174C"}, {"notes": {"original_bigg_ids": ["YKR009C"]}, "name": "FOX2", "id": "YKR009C"}, {"notes": {"original_bigg_ids": ["YOR393W"]}, "name": "ERR1", "id": "YOR393W"}, {"notes": {"original_bigg_ids": ["YPL281C"]}, "name": "ERR2", "id": "YPL281C"}, {"notes": {"original_bigg_ids": ["YMR323W"]}, "name": "ERR3", "id": "YMR323W"}, {"notes": {"original_bigg_ids": ["YGR254W"]}, "name": "ENO1", "id": "YGR254W"}, {"notes": {"original_bigg_ids": ["YHR174W"]}, "name": "ENO2", "id": "YHR174W"}, {"notes": {"original_bigg_ids": ["YBR184W"]}, "name": "None", "id": "YBR184W"}, {"notes": {"original_bigg_ids": ["YOR011W"]}, "name": "AUS1", "id": "YOR011W"}, {"notes": {"original_bigg_ids": ["YDR147W"]}, "name": "EKI1", "id": "YDR147W"}, {"notes": {"original_bigg_ids": ["YBR041W"]}, "name": "FAT1", "id": "YBR041W"}, {"notes": {"original_bigg_ids": ["YER015W"]}, "name": "FAA2", "id": "YER015W"}, {"notes": {"original_bigg_ids": ["YMR246W"]}, "name": "FAA4", "id": "YMR246W"}, {"notes": {"original_bigg_ids": ["YOR317W"]}, "name": "FAA1", "id": "YOR317W"}, {"notes": {"original_bigg_ids": ["YIL009W"]}, "name": "FAA3", "id": "YIL009W"}, {"notes": {"original_bigg_ids": ["YIL134W"]}, "name": "FLX1", "id": "YIL134W"}, {"notes": {"original_bigg_ids": ["YGR037C"]}, "name": "ACB1", "id": "YGR037C"}, {"notes": {"original_bigg_ids": ["YKL192C"]}, "name": "ACP1", "id": "YKL192C"}, {"notes": {"original_bigg_ids": ["YKL055C"]}, "name": "OAR1", "id": "YKL055C"}, {"notes": {"original_bigg_ids": ["YOR221C"]}, "name": "MCT1", "id": "YOR221C"}, {"notes": {"original_bigg_ids": ["YER183C"]}, "name": "FAU1", "id": "YER183C"}, {"notes": {"original_bigg_ids": ["YLR372W"]}, "name": "ELO3", "id": "YLR372W"}, {"notes": {"original_bigg_ids": ["YKL060C"]}, "name": "FBA1", "id": "YKL060C"}, {"notes": {"original_bigg_ids": ["YLR377C"]}, "name": "FBP1", "id": "YLR377C"}, {"notes": {"original_bigg_ids": ["YJL155C"]}, "name": "FBP26", "id": "YJL155C"}, {"notes": {"original_bigg_ids": ["YOR176W"]}, "name": "HEM15", "id": "YOR176W"}, {"notes": {"original_bigg_ids": ["YPL276W"]}, "name": "None", "id": "YPL276W"}, {"notes": {"original_bigg_ids": ["YOR388C"]}, "name": "FDH1", "id": "YOR388C"}, {"notes": {"original_bigg_ids": ["YPL275W"]}, "name": "None", "id": "YPL275W"}, {"notes": {"original_bigg_ids": ["YBL013W"]}, "name": "FMT1", "id": "YBL013W"}, {"notes": {"original_bigg_ids": ["YDL045C"]}, "name": "FAD1", "id": "YDL045C"}, {"notes": {"original_bigg_ids": ["YEL047C"]}, "name": "FRD1", "id": "YEL047C"}, {"notes": {"original_bigg_ids": ["YJR051W"]}, "name": "OSM1", "id": "YJR051W"}, {"notes": {"original_bigg_ids": ["YHR094C"]}, "name": "HXT1", "id": "YHR094C"}, {"notes": {"original_bigg_ids": ["YOL156W"]}, "name": "HXT11", "id": "YOL156W"}, {"notes": {"original_bigg_ids": ["YDR342C"]}, "name": "HXT7", "id": "YDR342C"}, {"notes": {"original_bigg_ids": ["YJR158W"]}, "name": "HXT16", "id": "YJR158W"}, {"notes": {"original_bigg_ids": ["YNR072W"]}, "name": "HXT17", "id": "YNR072W"}, {"notes": {"original_bigg_ids": ["YJL214W"]}, "name": "HXT8", "id": "YJL214W"}, {"notes": {"original_bigg_ids": ["YHR092C"]}, "name": "HXT4", "id": "YHR092C"}, {"notes": {"original_bigg_ids": ["YEL069C"]}, "name": "HXT13", "id": "YEL069C"}, {"notes": {"original_bigg_ids": ["YDL245C"]}, "name": "HXT15", "id": "YDL245C"}, {"notes": {"original_bigg_ids": ["YMR011W"]}, "name": "HXT2", "id": "YMR011W"}, {"notes": {"original_bigg_ids": ["YDR345C"]}, "name": "HXT3", "id": "YDR345C"}, {"notes": {"original_bigg_ids": ["YJL219W"]}, "name": "HXT9", "id": "YJL219W"}, {"notes": {"original_bigg_ids": ["YDR343C"]}, "name": "HXT6", "id": "YDR343C"}, {"notes": {"original_bigg_ids": ["YHR096C"]}, "name": "HXT5", "id": "YHR096C"}, {"notes": {"original_bigg_ids": ["YFL011W"]}, "name": "HXT10", "id": "YFL011W"}, {"notes": {"original_bigg_ids": ["YGR204W"]}, "name": "ADE3", "id": "YGR204W"}, {"notes": {"original_bigg_ids": ["YBR084W"]}, "name": "MIS1", "id": "YBR084W"}, {"notes": {"original_bigg_ids": ["YPL262W"]}, "name": "FUM1", "id": "YPL262W"}, {"notes": {"original_bigg_ids": ["YOR099W"]}, "name": "KTR1", "id": "YOR099W"}, {"notes": {"original_bigg_ids": ["YBR199W"]}, "name": "KTR4", "id": "YBR199W"}, {"notes": {"original_bigg_ids": ["YPL053C"]}, "name": "KTR6", "id": "YPL053C"}, {"notes": {"original_bigg_ids": ["YDR483W"]}, "name": "KRE2", "id": "YDR483W"}, {"notes": {"original_bigg_ids": ["YJL139C"]}, "name": "YUR1", "id": "YJL139C"}, {"notes": {"original_bigg_ids": ["YKR061W"]}, "name": "KTR2", "id": "YKR061W"}, {"notes": {"original_bigg_ids": ["YBR205W"]}, "name": "KTR3", "id": "YBR205W"}, {"notes": {"original_bigg_ids": ["YNL029C"]}, "name": "KTR5", "id": "YNL029C"}, {"notes": {"original_bigg_ids": ["YDL022W"]}, "name": "GPD1", "id": "YDL022W"}, {"notes": {"original_bigg_ids": ["YOL059W"]}, "name": "GPD2", "id": "YOL059W"}, {"notes": {"original_bigg_ids": ["YIL155C"]}, "name": "GUT2", "id": "YIL155C"}, {"notes": {"original_bigg_ids": ["YER062C"]}, "name": "GPP2", "id": "YER062C"}, {"notes": {"original_bigg_ids": ["YIL053W"]}, "name": "GPP1", "id": "YIL053W"}, {"notes": {"original_bigg_ids": ["YOR323C"]}, "name": "PRO2", "id": "YOR323C"}, {"notes": {"original_bigg_ids": ["YNL241C"]}, "name": "ZWF1", "id": "YNL241C"}, {"notes": {"original_bigg_ids": ["YBR196C"]}, "name": "PGI1", "id": "YBR196C"}, {"notes": {"original_bigg_ids": ["YBR020W"]}, "name": "GAL1", "id": "YBR020W"}, {"notes": {"original_bigg_ids": ["YBR018C"]}, "name": "GAL7", "id": "YBR018C"}, {"notes": {"original_bigg_ids": ["YKL035W"]}, "name": "UGP1", "id": "YKL035W"}, {"notes": {"original_bigg_ids": ["YHL012W"]}, "name": "None", "id": "YHL012W"}, {"notes": {"original_bigg_ids": ["YLR081W"]}, "name": "GAL2", "id": "YLR081W"}, {"notes": {"original_bigg_ids": ["YDR536W"]}, "name": "STL1", "id": "YDR536W"}, {"notes": {"original_bigg_ids": ["YNL318C"]}, "name": "HXT14", "id": "YNL318C"}, {"notes": {"original_bigg_ids": ["YGR192C"]}, "name": "TDH3", "id": "YGR192C"}, {"notes": {"original_bigg_ids": ["YJL052W"]}, "name": "TDH1", "id": "YJL052W"}, {"notes": {"original_bigg_ids": ["YJR009C"]}, "name": "TDH2", "id": "YJR009C"}, {"notes": {"original_bigg_ids": ["YDR408C"]}, "name": "ADE8", "id": "YDR408C"}, {"notes": {"original_bigg_ids": ["YEL011W"]}, "name": "GLC3", "id": "YEL011W"}, {"notes": {"original_bigg_ids": ["YMR189W"]}, "name": "GCV2", "id": "YMR189W"}, {"notes": {"original_bigg_ids": ["YAL044C"]}, "name": "GCV3", "id": "YAL044C"}, {"notes": {"original_bigg_ids": ["YDR019C"]}, "name": "GCV1", "id": "YDR019C"}, {"notes": {"original_bigg_ids": ["YMR085W"]}, "name": "None", "id": "YMR085W"}, {"notes": {"original_bigg_ids": ["YMR084W"]}, "name": "None", "id": "YMR084W"}, {"notes": {"original_bigg_ids": ["YKL104C"]}, "name": "GFA1", "id": "YKL104C"}, {"notes": {"original_bigg_ids": ["YLR058C"]}, "name": "SHM2", "id": "YLR058C"}, {"notes": {"original_bigg_ids": ["YBR263W"]}, "name": "SHM1", "id": "YBR263W"}, {"notes": {"original_bigg_ids": ["YPR160W"]}, "name": "GPH1", "id": "YPR160W"}, {"notes": {"original_bigg_ids": ["YLR258W"]}, "name": "GSY2", "id": "YLR258W"}, {"notes": {"original_bigg_ids": ["YFR015C"]}, "name": "GSY1", "id": "YFR015C"}, {"notes": {"original_bigg_ids": ["YPR035W"]}, "name": "GLN1", "id": "YPR035W"}, {"notes": {"original_bigg_ids": ["YOR168W"]}, "name": "GLN4", "id": "YOR168W"}, {"notes": {"original_bigg_ids": ["YLR195C"]}, "name": "NMT1", "id": "YLR195C"}, {"notes": {"original_bigg_ids": ["YDR300C"]}, "name": "PRO1", "id": "YDR300C"}, {"notes": {"original_bigg_ids": ["YJL101C"]}, "name": "GSH1", "id": "YJL101C"}, {"notes": {"original_bigg_ids": ["YMR250W"]}, "name": "GAD1", "id": "YMR250W"}, {"notes": {"original_bigg_ids": ["YDL215C"]}, "name": "GDH2", "id": "YDL215C"}, {"notes": {"original_bigg_ids": ["YOR375C"]}, "name": "GDH1", "id": "YOR375C"}, {"notes": {"original_bigg_ids": ["YAL062W"]}, "name": "GDH3", "id": "YAL062W"}, {"notes": {"original_bigg_ids": ["YCL040W"]}, "name": "GLK1", "id": "YCL040W"}, {"notes": {"original_bigg_ids": ["YMR300C"]}, "name": "ADE4", "id": "YMR300C"}, {"notes": {"original_bigg_ids": ["YDL171C"]}, "name": "GLT1", "id": "YDL171C"}, {"notes": {"original_bigg_ids": ["YGL245W"]}, "name": "GUS1", "id": "YGL245W"}, {"notes": {"original_bigg_ids": ["YOL033W"]}, "name": "MSE1", "id": "YOL033W"}, {"notes": {"original_bigg_ids": ["YLL043W"]}, "name": "FPS1", "id": "YLL043W"}, {"notes": {"original_bigg_ids": ["YHL032C"]}, "name": "GUT1", "id": "YHL032C"}, {"notes": {"original_bigg_ids": ["YDR272W"]}, "name": "GLO2", "id": "YDR272W"}, {"notes": {"original_bigg_ids": ["YOR040W"]}, "name": "GLO4", "id": "YOR040W"}, {"notes": {"original_bigg_ids": ["YBR121C"]}, "name": "GRS1", "id": "YBR121C"}, {"notes": {"original_bigg_ids": ["YPR081C"]}, "name": "GRS2", "id": "YPR081C"}, {"notes": {"original_bigg_ids": ["YMR217W"]}, "name": "GUA1", "id": "YMR217W"}, {"notes": {"original_bigg_ids": ["YGR256W"]}, "name": "GND2", "id": "YGR256W"}, {"notes": {"original_bigg_ids": ["YHR183W"]}, "name": "GND1", "id": "YHR183W"}, {"notes": {"original_bigg_ids": ["YPL091W"]}, "name": "GLR1", "id": "YPL091W"}, {"notes": {"original_bigg_ids": ["YBR244W"]}, "name": "GPX2", "id": "YBR244W"}, {"notes": {"original_bigg_ids": ["YKL026C"]}, "name": "GPX1", "id": "YKL026C"}, {"notes": {"original_bigg_ids": ["YIR037W"]}, "name": "HYR1", "id": "YIR037W"}, {"notes": {"original_bigg_ids": ["YOL049W"]}, "name": "GSH2", "id": "YOL049W"}, {"notes": {"original_bigg_ids": ["YLR299W"]}, "name": "ECM38", "id": "YLR299W"}, {"notes": {"original_bigg_ids": ["YGR267C"]}, "name": "FOL2", "id": "YGR267C"}, {"notes": {"original_bigg_ids": ["YBL033C"]}, "name": "RIB1", "id": "YBL033C"}, {"notes": {"original_bigg_ids": ["YDR399W"]}, "name": "HPT1", "id": "YDR399W"}, {"notes": {"original_bigg_ids": ["YDR234W"]}, "name": "LYS4", "id": "YDR234W"}, {"notes": {"original_bigg_ids": ["YMR101C"]}, "name": "SRT1", "id": "YMR101C"}, {"notes": {"original_bigg_ids": ["YGL155W"]}, "name": "CDC43", "id": "YGL155W"}, {"notes": {"original_bigg_ids": ["YJL031C"]}, "name": "BET4", "id": "YJL031C"}, {"notes": {"original_bigg_ids": ["YDL090C"]}, "name": "RAM1", "id": "YDL090C"}, {"notes": {"original_bigg_ids": ["YPR176C"]}, "name": "BET2", "id": "YPR176C"}, {"notes": {"original_bigg_ids": ["YBR002C"]}, "name": "RER2", "id": "YBR002C"}, {"notes": {"original_bigg_ids": ["YKL019W"]}, "name": "RAM2", "id": "YKL019W"}, {"notes": {"original_bigg_ids": ["YNR041C"]}, "name": "COQ2", "id": "YNR041C"}, {"notes": {"original_bigg_ids": ["YBR003W"]}, "name": "COQ1", "id": "YBR003W"}, {"notes": {"original_bigg_ids": ["YPL172C"]}, "name": "COX10", "id": "YPL172C"}, {"notes": {"original_bigg_ids": ["YDL182W"]}, "name": "LYS20", "id": "YDL182W"}, {"notes": {"original_bigg_ids": ["YDL131W"]}, "name": "LYS21", "id": "YDL131W"}, {"notes": {"original_bigg_ids": ["YLL062C"]}, "name": "MHT1", "id": "YLL062C"}, {"notes": {"original_bigg_ids": ["YPL273W"]}, "name": "SAM4", "id": "YPL273W"}, {"notes": {"original_bigg_ids": ["YPL214C"]}, "name": "THI6", "id": "YPL214C"}, {"notes": {"original_bigg_ids": ["YGL253W"]}, "name": "HXK2", "id": "YGL253W"}, {"notes": {"original_bigg_ids": ["YFR053C"]}, "name": "HXK1", "id": "YFR053C"}, {"notes": {"original_bigg_ids": ["YIL094C"]}, "name": "LYS12", "id": "YIL094C"}, {"notes": {"original_bigg_ids": ["YCL030C"]}, "name": "HIS4", "id": "YCL030C"}, {"notes": {"original_bigg_ids": ["YFR025C"]}, "name": "HIS2", "id": "YFR025C"}, {"notes": {"original_bigg_ids": ["YPR033C"]}, "name": "HTS1", "id": "YPR033C"}, {"notes": {"original_bigg_ids": ["YGR191W"]}, "name": "HIP1", "id": "YGR191W"}, {"notes": {"original_bigg_ids": ["YLR231C"]}, "name": "BNA5", "id": "YLR231C"}, {"notes": {"original_bigg_ids": ["YDL205C"]}, "name": "HEM3", "id": "YDL205C"}, {"notes": {"original_bigg_ids": ["YLR450W"]}, "name": "HMG2", "id": "YLR450W"}, {"notes": {"original_bigg_ids": ["YML075C"]}, "name": "HMG1", "id": "YML075C"}, {"notes": {"original_bigg_ids": ["YML126C"]}, "name": "ERG13", "id": "YML126C"}, {"notes": {"original_bigg_ids": ["YPR121W"]}, "name": "THI22", "id": "YPR121W"}, {"notes": {"original_bigg_ids": ["YOL055C"]}, "name": "THI20", "id": "YOL055C"}, {"notes": {"original_bigg_ids": ["YPL258C"]}, "name": "THI21", "id": "YPL258C"}, {"notes": {"original_bigg_ids": ["YER023W"]}, "name": "PRO3", "id": "YER023W"}, {"notes": {"original_bigg_ids": ["YJR139C"]}, "name": "HOM6", "id": "YJR139C"}, {"notes": {"original_bigg_ids": ["YNL277W"]}, "name": "MET2", "id": "YNL277W"}, {"notes": {"original_bigg_ids": ["YHR025W"]}, "name": "THR1", "id": "YHR025W"}, {"notes": {"original_bigg_ids": ["YIL116W"]}, "name": "HIS5", "id": "YIL116W"}, {"notes": {"original_bigg_ids": ["YNL037C"]}, "name": "IDH1", "id": "YNL037C"}, {"notes": {"original_bigg_ids": ["YOR136W"]}, "name": "IDH2", "id": "YOR136W"}, {"notes": {"original_bigg_ids": ["YLR174W"]}, "name": "IDP2", "id": "YLR174W"}, {"notes": {"original_bigg_ids": ["YDL066W"]}, "name": "IDP1", "id": "YDL066W"}, {"notes": {"original_bigg_ids": ["YNL009W"]}, "name": "IDP3", "id": "YNL009W"}, {"notes": {"original_bigg_ids": ["YER065C"]}, "name": "ICL1", "id": "YER065C"}, {"notes": {"original_bigg_ids": ["YBR248C"]}, "name": "HIS7", "id": "YBR248C"}, {"notes": {"original_bigg_ids": ["YOR202W"]}, "name": "HIS3", "id": "YOR202W"}, {"notes": {"original_bigg_ids": ["YJR148W"]}, "name": "BAT2", "id": "YJR148W"}, {"notes": {"original_bigg_ids": ["YHR208W"]}, "name": "BAT1", "id": "YHR208W"}, {"notes": {"original_bigg_ids": ["YBL076C"]}, "name": "ILS1", "id": "YBL076C"}, {"notes": {"original_bigg_ids": ["YPL040C"]}, "name": "ISM1", "id": "YPL040C"}, {"notes": {"original_bigg_ids": ["YAR073W"]}, "name": "None", "id": "YAR073W"}, {"notes": {"original_bigg_ids": ["YML056C"]}, "name": "IMD4", "id": "YML056C"}, {"notes": {"original_bigg_ids": ["YLR432W"]}, "name": "IMD3", "id": "YLR432W"}, {"notes": {"original_bigg_ids": ["YHR216W"]}, "name": "IMD2", "id": "YHR216W"}, {"notes": {"original_bigg_ids": ["YAR075W"]}, "name": "None", "id": "YAR075W"}, {"notes": {"original_bigg_ids": ["YDR380W"]}, "name": "ARO10", "id": "YDR380W"}, {"notes": {"original_bigg_ids": ["YDR497C"]}, "name": "ITR1", "id": "YDR497C"}, {"notes": {"original_bigg_ids": ["YOL103W"]}, "name": "ITR2", "id": "YOL103W"}, {"notes": {"original_bigg_ids": ["YKL004W"]}, "name": "AUR1", "id": "YKL004W"}, {"notes": {"original_bigg_ids": ["YCL018W"]}, "name": "LEU2", "id": "YCL018W"}, {"notes": {"original_bigg_ids": ["YGL009C"]}, "name": "LEU1", "id": "YGL009C"}, {"notes": {"original_bigg_ids": ["YOR108W"]}, "name": "LEU9", "id": "YOR108W"}, {"notes": {"original_bigg_ids": ["YNL104C"]}, "name": "LEU4", "id": "YNL104C"}, {"notes": {"original_bigg_ids": ["YOR142W"]}, "name": "LSC1", "id": "YOR142W"}, {"notes": {"original_bigg_ids": ["YGR244C"]}, "name": "LSC2", "id": "YGR244C"}, {"notes": {"original_bigg_ids": ["YBL098W"]}, "name": "BNA4", "id": "YBL098W"}, {"notes": {"original_bigg_ids": ["YPL160W"]}, "name": "CDC60", "id": "YPL160W"}, {"notes": {"original_bigg_ids": ["YLR382C"]}, "name": "NAM2", "id": "YLR382C"}, {"notes": {"original_bigg_ids": ["YML004C"]}, "name": "GLO1", "id": "YML004C"}, {"notes": {"original_bigg_ids": ["YHR007C"]}, "name": "ERG11", "id": "YHR007C"}, {"notes": {"original_bigg_ids": ["YHR072W"]}, "name": "ERG7", "id": "YHR072W"}, {"notes": {"original_bigg_ids": ["YDR037W"]}, "name": "KRS1", "id": "YDR037W"}, {"notes": {"original_bigg_ids": ["YNL073W"]}, "name": "MSK1", "id": "YNL073W"}, {"notes": {"original_bigg_ids": ["YNL268W"]}, "name": "LYP1", "id": "YNL268W"}, {"notes": {"original_bigg_ids": ["YML054C"]}, "name": "CYB2", "id": "YML054C"}, {"notes": {"original_bigg_ids": ["YKL217W"]}, "name": "JEN1", "id": "YKL217W"}, {"notes": {"original_bigg_ids": ["YIR031C"]}, "name": "DAL7", "id": "YIR031C"}, {"notes": {"original_bigg_ids": ["YNL117W"]}, "name": "MLS1", "id": "YNL117W"}, {"notes": {"original_bigg_ids": ["YIL172C"]}, "name": "IMA3", "id": "YIL172C"}, {"notes": {"original_bigg_ids": ["YGR287C"]}, "name": "IMA1", "id": "YGR287C"}, {"notes": {"original_bigg_ids": ["YGR292W"]}, "name": "MAL12", "id": "YGR292W"}, {"notes": {"original_bigg_ids": ["YBR299W"]}, "name": "MAL32", "id": "YBR299W"}, {"notes": {"original_bigg_ids": ["YJL216C"]}, "name": "IMA5", "id": "YJL216C"}, {"notes": {"original_bigg_ids": ["YDL247W"]}, "name": "MPH2", "id": "YDL247W"}, {"notes": {"original_bigg_ids": ["YGR289C"]}, "name": "MAL11", "id": "YGR289C"}, {"notes": {"original_bigg_ids": ["YJR160C"]}, "name": "MPH3", "id": "YJR160C"}, {"notes": {"original_bigg_ids": ["YBR298C"]}, "name": "MAL31", "id": "YBR298C"}, {"notes": {"original_bigg_ids": ["YDL055C"]}, "name": "PSA1", "id": "YDL055C"}, {"notes": {"original_bigg_ids": ["YER003C"]}, "name": "PMI40", "id": "YER003C"}, {"notes": {"original_bigg_ids": ["YPR006C"]}, "name": "ICL2", "id": "YPR006C"}, {"notes": {"original_bigg_ids": ["YOL126C"]}, "name": "MDH2", "id": "YOL126C"}, {"notes": {"original_bigg_ids": ["YKL085W"]}, "name": "MDH1", "id": "YKL085W"}, {"notes": {"original_bigg_ids": ["YDL078C"]}, "name": "MDH3", "id": "YDL078C"}, {"notes": {"original_bigg_ids": ["YKL029C"]}, "name": "MAE1", "id": "YKL029C"}, {"notes": {"original_bigg_ids": ["YDR502C"]}, "name": "SAM2", "id": "YDR502C"}, {"notes": {"original_bigg_ids": ["YLR180W"]}, "name": "SAM1", "id": "YLR180W"}, {"notes": {"original_bigg_ids": ["YJR130C"]}, "name": "STR2", "id": "YJR130C"}, {"notes": {"original_bigg_ids": ["YER091C"]}, "name": "MET6", "id": "YER091C"}, {"notes": {"original_bigg_ids": ["YGR264C"]}, "name": "MES1", "id": "YGR264C"}, {"notes": {"original_bigg_ids": ["YGR171C"]}, "name": "MSM1", "id": "YGR171C"}, {"notes": {"original_bigg_ids": ["YHL036W"]}, "name": "MUP3", "id": "YHL036W"}, {"notes": {"original_bigg_ids": ["YGR055W"]}, "name": "MUP1", "id": "YGR055W"}, {"notes": {"original_bigg_ids": ["YMR208W"]}, "name": "ERG12", "id": "YMR208W"}, {"notes": {"original_bigg_ids": ["YJR073C"]}, "name": "OPI3", "id": "YJR073C"}, {"notes": {"original_bigg_ids": ["YHR046C"]}, "name": "INM1", "id": "YHR046C"}, {"notes": {"original_bigg_ids": ["YJL153C"]}, "name": "INO1", "id": "YJL153C"}, {"notes": {"original_bigg_ids": ["YDR072C"]}, "name": "IPT1", "id": "YDR072C"}, {"notes": {"original_bigg_ids": ["YBR036C"]}, "name": "CSG2", "id": "YBR036C"}, {"notes": {"original_bigg_ids": ["YPL057C"]}, "name": "SUR1", "id": "YPL057C"}, {"notes": {"original_bigg_ids": ["YLL061W"]}, "name": "MMP1", "id": "YLL061W"}, {"notes": {"original_bigg_ids": ["YBR176W"]}, "name": "ECM31", "id": "YBR176W"}, {"notes": {"original_bigg_ids": ["YKR080W"]}, "name": "MTD1", "id": "YKR080W"}, {"notes": {"original_bigg_ids": ["YPL023C"]}, "name": "MET12", "id": "YPL023C"}, {"notes": {"original_bigg_ids": ["YGL125W"]}, "name": "MET13", "id": "YGL125W"}, {"notes": {"original_bigg_ids": ["YGL067W"]}, "name": "NPY1", "id": "YGL067W"}, {"notes": {"original_bigg_ids": ["YDL085W"]}, "name": "NDE2", "id": "YDL085W"}, {"notes": {"original_bigg_ids": ["YMR145C"]}, "name": "NDE1", "id": "YMR145C"}, {"notes": {"original_bigg_ids": ["YML120C"]}, "name": "NDI1", "id": "YML120C"}, {"notes": {"original_bigg_ids": ["YEL041W"]}, "name": "YEF1", "id": "YEL041W"}, {"notes": {"original_bigg_ids": ["YPL188W"]}, "name": "POS5", "id": "YPL188W"}, {"notes": {"original_bigg_ids": ["YJR049C"]}, "name": "UTR1", "id": "YJR049C"}, {"notes": {"original_bigg_ids": ["YHR074W"]}, "name": "QNS1", "id": "YHR074W"}, {"notes": {"original_bigg_ids": ["YOR209C"]}, "name": "NPT1", "id": "YOR209C"}, {"notes": {"original_bigg_ids": ["YLR138W"]}, "name": "NHA1", "id": "YLR138W"}, {"notes": {"original_bigg_ids": ["YEL042W"]}, "name": "GDA1", "id": "YEL042W"}, {"notes": {"original_bigg_ids": ["YKL067W"]}, "name": "YNK1", "id": "YKL067W"}, {"notes": {"original_bigg_ids": ["YNL142W"]}, "name": "MEP2", "id": "YNL142W"}, {"notes": {"original_bigg_ids": ["YGR121C"]}, "name": "MEP1", "id": "YGR121C"}, {"notes": {"original_bigg_ids": ["YPR138C"]}, "name": "MEP3", "id": "YPR138C"}, {"notes": {"original_bigg_ids": ["YGR010W"]}, "name": "NMA2", "id": "YGR010W"}, {"notes": {"original_bigg_ids": ["YLR328W"]}, "name": "NMA1", "id": "YLR328W"}, {"notes": {"original_bigg_ids": ["YGL037C"]}, "name": "PNC1", "id": "YGL037C"}, {"notes": {"original_bigg_ids": ["YFR047C"]}, "name": "BNA6", "id": "YFR047C"}, {"notes": {"original_bigg_ids": ["YLR351C"]}, "name": "NIT3", "id": "YLR351C"}, {"notes": {"original_bigg_ids": ["YJL126W"]}, "name": "NIT2", "id": "YJL126W"}, {"notes": {"original_bigg_ids": ["YKL120W"]}, "name": "OAC1", "id": "YKL120W"}, {"notes": {"original_bigg_ids": ["YJL088W"]}, "name": "ARG3", "id": "YJL088W"}, {"notes": {"original_bigg_ids": ["YOR184W"]}, "name": "SER1", "id": "YOR184W"}, {"notes": {"original_bigg_ids": ["YPL266W"]}, "name": "DIM1", "id": "YPL266W"}, {"notes": {"original_bigg_ids": ["YML110C"]}, "name": "COQ5", "id": "YML110C"}, {"notes": {"original_bigg_ids": ["YGR255C"]}, "name": "COQ6", "id": "YGR255C"}, {"notes": {"original_bigg_ids": ["YEL021W"]}, "name": "URA3", "id": "YEL021W"}, {"notes": {"original_bigg_ids": ["YDR538W"]}, "name": "PAD1", "id": "YDR538W"}, {"notes": {"original_bigg_ids": ["YKL184W"]}, "name": "SPE1", "id": "YKL184W"}, {"notes": {"original_bigg_ids": ["YLR438W"]}, "name": "CAR2", "id": "YLR438W"}, {"notes": {"original_bigg_ids": ["YOR130C"]}, "name": "ORT1", "id": "YOR130C"}, {"notes": {"original_bigg_ids": ["YMR271C"]}, "name": "URA10", "id": "YMR271C"}, {"notes": {"original_bigg_ids": ["YML106W"]}, "name": "URA5", "id": "YML106W"}, {"notes": {"original_bigg_ids": ["YPL134C"]}, "name": "ODC1", "id": "YPL134C"}, {"notes": {"original_bigg_ids": ["YOR222W"]}, "name": "ODC2", "id": "YOR222W"}, {"notes": {"original_bigg_ids": ["YIL145C"]}, "name": "PAN6", "id": "YIL145C"}, {"notes": {"original_bigg_ids": ["YPR167C"]}, "name": "MET16", "id": "YPR167C"}, {"notes": {"original_bigg_ids": ["YBR218C"]}, "name": "PYC2", "id": "YBR218C"}, {"notes": {"original_bigg_ids": ["YGL062W"]}, "name": "PYC1", "id": "YGL062W"}, {"notes": {"original_bigg_ids": ["YOR360C"]}, "name": "PDE2", "id": "YOR360C"}, {"notes": {"original_bigg_ids": ["YGL248W"]}, "name": "PDE1", "id": "YGL248W"}, {"notes": {"original_bigg_ids": ["YER178W"]}, "name": "PDA1", "id": "YER178W"}, {"notes": {"original_bigg_ids": ["YNL071W"]}, "name": "LAT1", "id": "YNL071W"}, {"notes": {"original_bigg_ids": ["YBR221C"]}, "name": "PDB1", "id": "YBR221C"}, {"notes": {"original_bigg_ids": ["YBR035C"]}, "name": "PDX3", "id": "YBR035C"}, {"notes": {"original_bigg_ids": ["YDL040C"]}, "name": "NAT1", "id": "YDL040C"}, {"notes": {"original_bigg_ids": ["YGR147C"]}, "name": "NAT2", "id": "YGR147C"}, {"notes": {"original_bigg_ids": ["YKR093W"]}, "name": "PTR2", "id": "YKR093W"}, {"notes": {"original_bigg_ids": ["YGR007W"]}, "name": "ECT1", "id": "YGR007W"}, {"notes": {"original_bigg_ids": ["YGR157W"]}, "name": "CHO2", "id": "YGR157W"}, {"notes": {"original_bigg_ids": ["YMR205C"]}, "name": "PFK2", "id": "YMR205C"}, {"notes": {"original_bigg_ids": ["YGR240C"]}, "name": "PFK1", "id": "YGR240C"}, {"notes": {"original_bigg_ids": ["YOL136C"]}, "name": "PFK27", "id": "YOL136C"}, {"notes": {"original_bigg_ids": ["YIL107C"]}, "name": "PFK26", "id": "YIL107C"}, {"notes": {"original_bigg_ids": ["YER081W"]}, "name": "SER3", "id": "YER081W"}, {"notes": {"original_bigg_ids": ["YIL074C"]}, "name": "SER33", "id": "YIL074C"}, {"notes": {"original_bigg_ids": ["YCR012W"]}, "name": "PGK1", "id": "YCR012W"}, {"notes": {"original_bigg_ids": ["YNR034W"]}, "name": "SOL1", "id": "YNR034W"}, {"notes": {"original_bigg_ids": ["YGR248W"]}, "name": "SOL4", "id": "YGR248W"}, {"notes": {"original_bigg_ids": ["YHR163W"]}, "name": "SOL3", "id": "YHR163W"}, {"notes": {"original_bigg_ids": ["YDL021W"]}, "name": "GPM2", "id": "YDL021W"}, {"notes": {"original_bigg_ids": ["YOL056W"]}, "name": "GPM3", "id": "YOL056W"}, {"notes": {"original_bigg_ids": ["YMR105C"]}, "name": "PGM2", "id": "YMR105C"}, {"notes": {"original_bigg_ids": ["YKL127W"]}, "name": "PGM1", "id": "YKL127W"}, {"notes": {"original_bigg_ids": ["YHR137W"]}, "name": "ARO9", "id": "YHR137W"}, {"notes": {"original_bigg_ids": ["YLR060W"]}, "name": "FRS1", "id": "YLR060W"}, {"notes": {"original_bigg_ids": ["YFL022C"]}, "name": "FRS2", "id": "YFL022C"}, {"notes": {"original_bigg_ids": ["YPR047W"]}, "name": "MSF1", "id": "YPR047W"}, {"notes": {"original_bigg_ids": ["YPL268W"]}, "name": "PLC1", "id": "YPL268W"}, {"notes": {"original_bigg_ids": ["YFR019W"]}, "name": "FAB1", "id": "YFR019W"}, {"notes": {"original_bigg_ids": ["YDR208W"]}, "name": "MSS4", "id": "YDR208W"}, {"notes": {"original_bigg_ids": ["YLR240W"]}, "name": "VPS34", "id": "YLR240W"}, {"notes": {"original_bigg_ids": ["YKL203C"]}, "name": "TOR2", "id": "YKL203C"}, {"notes": {"original_bigg_ids": ["YJR066W"]}, "name": "TOR1", "id": "YJR066W"}, {"notes": {"original_bigg_ids": ["YNL267W"]}, "name": "PIK1", "id": "YNL267W"}, {"notes": {"original_bigg_ids": ["YLR305C"]}, "name": "STT4", "id": "YLR305C"}, {"notes": {"original_bigg_ids": ["YPR113W"]}, "name": "PIS1", "id": "YPR113W"}, {"notes": {"original_bigg_ids": ["YJR077C"]}, "name": "MIR1", "id": "YJR077C"}, {"notes": {"original_bigg_ids": ["YCR098C"]}, "name": "GIT1", "id": "YCR098C"}, {"notes": {"original_bigg_ids": ["YJL198W"]}, "name": "PHO90", "id": "YJL198W"}, {"notes": {"original_bigg_ids": ["YCR037C"]}, "name": "PHO87", "id": "YCR037C"}, {"notes": {"original_bigg_ids": ["YBR296C"]}, "name": "PHO89", "id": "YBR296C"}, {"notes": {"original_bigg_ids": ["YNR013C"]}, "name": "PHO91", "id": "YNR013C"}, {"notes": {"original_bigg_ids": ["YML123C"]}, "name": "PHO84", "id": "YML123C"}, {"notes": {"original_bigg_ids": ["YER053C"]}, "name": "PIC2", "id": "YER053C"}, {"notes": {"original_bigg_ids": ["YFL045C"]}, "name": "SEC53", "id": "YFL045C"}, {"notes": {"original_bigg_ids": ["YMR220W"]}, "name": "ERG8", "id": "YMR220W"}, {"notes": {"original_bigg_ids": ["YDR531W"]}, "name": "CAB1", "id": "YDR531W"}, {"notes": {"original_bigg_ids": ["YCR028C"]}, "name": "FEN2", "id": "YCR028C"}, {"notes": {"original_bigg_ids": ["YBR011C"]}, "name": "IPP1", "id": "YBR011C"}, {"notes": {"original_bigg_ids": ["YMR267W"]}, "name": "PPA2", "id": "YMR267W"}, {"notes": {"original_bigg_ids": ["YGL040C"]}, "name": "HEM2", "id": "YGL040C"}, {"notes": {"original_bigg_ids": ["YKR097W"]}, "name": "PCK1", "id": "YKR097W"}, {"notes": {"original_bigg_ids": ["YBR166C"]}, "name": "TYR1", "id": "YBR166C"}, {"notes": {"original_bigg_ids": ["YNL316C"]}, "name": "PHA2", "id": "YNL316C"}, {"notes": {"original_bigg_ids": ["YER014W"]}, "name": "HEM14", "id": "YER014W"}, {"notes": {"original_bigg_ids": ["YGL234W"]}, "name": "ADE5,7", "id": "YGL234W"}, {"notes": {"original_bigg_ids": ["YDR007W"]}, "name": "TRP1", "id": "YDR007W"}, {"notes": {"original_bigg_ids": ["YAR015W"]}, "name": "ADE1", "id": "YAR015W"}, {"notes": {"original_bigg_ids": ["YGR061C"]}, "name": "ADE6", "id": "YGR061C"}, {"notes": {"original_bigg_ids": ["YIL020C"]}, "name": "HIS6", "id": "YIL020C"}, {"notes": {"original_bigg_ids": ["YLR142W"]}, "name": "PUT1", "id": "YLR142W"}, {"notes": {"original_bigg_ids": ["YER087W"]}, "name": "AIM10", "id": "YER087W"}, {"notes": {"original_bigg_ids": ["YHR020W"]}, "name": "None", "id": "YHR020W"}, {"notes": {"original_bigg_ids": ["YKL181W"]}, "name": "PRS1", "id": "YKL181W"}, {"notes": {"original_bigg_ids": ["YER099C"]}, "name": "PRS2", "id": "YER099C"}, {"notes": {"original_bigg_ids": ["YBL068W"]}, "name": "PRS4", "id": "YBL068W"}, {"notes": {"original_bigg_ids": ["YOL061W"]}, "name": "PRS5", "id": "YOL061W"}, {"notes": {"original_bigg_ids": ["YHL011C"]}, "name": "PRS3", "id": "YHL011C"}, {"notes": {"original_bigg_ids": ["YGR170W"]}, "name": "PSD2", "id": "YGR170W"}, {"notes": {"original_bigg_ids": ["YNL169C"]}, "name": "PSD1", "id": "YNL169C"}, {"notes": {"original_bigg_ids": ["YER026C"]}, "name": "CHO1", "id": "YER026C"}, {"notes": {"original_bigg_ids": ["YDR294C"]}, "name": "DPL1", "id": "YDR294C"}, {"notes": {"original_bigg_ids": ["YGR208W"]}, "name": "SER2", "id": "YGR208W"}, {"notes": {"original_bigg_ids": ["YOR347C"]}, "name": "PYK2", "id": "YOR347C"}, {"notes": {"original_bigg_ids": ["YAL038W"]}, "name": "CDC19", "id": "YAL038W"}, {"notes": {"original_bigg_ids": ["YLR044C"]}, "name": "PDC1", "id": "YLR044C"}, {"notes": {"original_bigg_ids": ["YGR087C"]}, "name": "PDC6", "id": "YGR087C"}, {"notes": {"original_bigg_ids": ["YLR134W"]}, "name": "PDC5", "id": "YLR134W"}, {"notes": {"original_bigg_ids": ["YDR236C"]}, "name": "FMN1", "id": "YDR236C"}, {"notes": {"original_bigg_ids": ["YOL143C"]}, "name": "RIB4", "id": "YOL143C"}, {"notes": {"original_bigg_ids": ["YBR256C"]}, "name": "RIB5", "id": "YBR256C"}, {"notes": {"original_bigg_ids": ["YJL026W"]}, "name": "RNR2", "id": "YJL026W"}, {"notes": {"original_bigg_ids": ["YIL066C"]}, "name": "RNR3", "id": "YIL066C"}, {"notes": {"original_bigg_ids": ["YER070W"]}, "name": "RNR1", "id": "YER070W"}, {"notes": {"original_bigg_ids": ["YGR180C"]}, "name": "RNR4", "id": "YGR180C"}, {"notes": {"original_bigg_ids": ["YJL121C"]}, "name": "RPE1", "id": "YJL121C"}, {"notes": {"original_bigg_ids": ["YOR095C"]}, "name": "RKI1", "id": "YOR095C"}, {"notes": {"original_bigg_ids": ["YNR050C"]}, "name": "LYS9", "id": "YNR050C"}, {"notes": {"original_bigg_ids": ["YIR034C"]}, "name": "LYS1", "id": "YIR034C"}, {"notes": {"original_bigg_ids": ["YJR010W"]}, "name": "MET3", "id": "YJR010W"}, {"notes": {"original_bigg_ids": ["YML008C"]}, "name": "ERG6", "id": "YML008C"}, {"notes": {"original_bigg_ids": ["YKR053C"]}, "name": "YSR3", "id": "YKR053C"}, {"notes": {"original_bigg_ids": ["YJL134W"]}, "name": "LCB3", "id": "YJL134W"}, {"notes": {"original_bigg_ids": ["YJR159W"]}, "name": "SOR1", "id": "YJR159W"}, {"notes": {"original_bigg_ids": ["YIL168W"]}, "name": "SDL1", "id": "YIL167W"}, {"notes": {"original_bigg_ids": ["YCL064C"]}, "name": "CHA1", "id": "YCL064C"}, {"notes": {"original_bigg_ids": ["YDR062W"]}, "name": "LCB2", "id": "YDR062W"}, {"notes": {"original_bigg_ids": ["YMR296C"]}, "name": "LCB1", "id": "YMR296C"}, {"notes": {"original_bigg_ids": ["YDR023W"]}, "name": "SES1", "id": "YDR023W"}, {"notes": {"original_bigg_ids": ["YHR011W"]}, "name": "DIA4", "id": "YHR011W"}, {"notes": {"original_bigg_ids": ["YJL068C"]}, "name": "None", "id": "YJL068C"}, {"notes": {"original_bigg_ids": ["YML082W"]}, "name": "None", "id": "YML082W"}, {"notes": {"original_bigg_ids": ["YOR171C"]}, "name": "LCB4", "id": "YOR171C"}, {"notes": {"original_bigg_ids": ["YLR260W"]}, "name": "LCB5", "id": "YLR260W"}, {"notes": {"original_bigg_ids": ["YGR125W"]}, "name": "None", "id": "YGR125W"}, {"notes": {"original_bigg_ids": ["YLR092W"]}, "name": "SUL2", "id": "YLR092W"}, {"notes": {"original_bigg_ids": ["YBR294W"]}, "name": "SUL1", "id": "YBR294W"}, {"notes": {"original_bigg_ids": ["YPR069C"]}, "name": "SPE3", "id": "YPR069C"}, {"notes": {"original_bigg_ids": ["YLR146C"]}, "name": "SPE4", "id": "YLR146C"}, {"notes": {"original_bigg_ids": ["YGR175C"]}, "name": "ERG1", "id": "YGR175C"}, {"notes": {"original_bigg_ids": ["YHR190W"]}, "name": "ERG9", "id": "YHR190W"}, {"notes": {"original_bigg_ids": ["YBR006W"]}, "name": "UGA2", "id": "YBR006W"}, {"notes": {"original_bigg_ids": ["YDR178W"]}, "name": "SDH4", "id": "YDR178W"}, {"notes": {"original_bigg_ids": ["YLL041C"]}, "name": "SDH2", "id": "YLL041C"}, {"notes": {"original_bigg_ids": ["YMR118C"]}, "name": "SHH3", "id": "YMR118C"}, {"notes": {"original_bigg_ids": ["YKL141W"]}, "name": "SDH3", "id": "YKL141W"}, {"notes": {"original_bigg_ids": ["YJL045W"]}, "name": "None", "id": "YJL045W"}, {"notes": {"original_bigg_ids": ["YLR164W"]}, "name": "SHH4", "id": "YLR164W"}, {"notes": {"original_bigg_ids": ["YKL148C"]}, "name": "SDH1", "id": "YKL148C"}, {"notes": {"original_bigg_ids": ["YJR095W"]}, "name": "SFC1", "id": "YJR095W"}, {"notes": {"original_bigg_ids": ["YIL162W"]}, "name": "SUC2", "id": "YIL162W"}, {"notes": {"original_bigg_ids": ["YJR137C"]}, "name": "MET5", "id": "YJR137C"}, {"notes": {"original_bigg_ids": ["YFR030W"]}, "name": "MET10", "id": "YFR030W"}, {"notes": {"original_bigg_ids": ["YLR354C"]}, "name": "TAL1", "id": "YLR354C"}, {"notes": {"original_bigg_ids": ["YGR043C"]}, "name": "NQM1", "id": "YGR043C"}, {"notes": {"original_bigg_ids": ["YKL132C"]}, "name": "RMA1", "id": "YKL132C"}, {"notes": {"original_bigg_ids": ["YOR241W"]}, "name": "MET7", "id": "YOR241W"}, {"notes": {"original_bigg_ids": ["YMR113W"]}, "name": "FOL3", "id": "YMR113W"}, {"notes": {"original_bigg_ids": ["YBR092C"]}, "name": "PHO3", "id": "YBR092C"}, {"notes": {"original_bigg_ids": ["YOR192C"]}, "name": "THI72", "id": "YOR192C"}, {"notes": {"original_bigg_ids": ["YOR071C"]}, "name": "NRT1", "id": "YOR071C"}, {"notes": {"original_bigg_ids": ["YLR237W"]}, "name": "THI7", "id": "YLR237W"}, {"notes": {"original_bigg_ids": ["YEL046C"]}, "name": "GLY1", "id": "YEL046C"}, {"notes": {"original_bigg_ids": ["YKL218C"]}, "name": "SRY1", "id": "YKL218C"}, {"notes": {"original_bigg_ids": ["YER086W"]}, "name": "ILV1", "id": "YER086W"}, {"notes": {"original_bigg_ids": ["YIL078W"]}, "name": "THS1", "id": "YIL078W"}, {"notes": {"original_bigg_ids": ["YKL194C"]}, "name": "MST1", "id": "YKL194C"}, {"notes": {"original_bigg_ids": ["YPR074C"]}, "name": "TKL1", "id": "YPR074C"}, {"notes": {"original_bigg_ids": ["YBR117C"]}, "name": "TKL2", "id": "YBR117C"}, {"notes": {"original_bigg_ids": ["YOR143C"]}, "name": "THI80", "id": "YOR143C"}, {"notes": {"original_bigg_ids": ["YOR074C"]}, "name": "CDC21", "id": "YOR074C"}, {"notes": {"original_bigg_ids": ["YDR050C"]}, "name": "TPI1", "id": "YDR050C"}, {"notes": {"original_bigg_ids": ["YDR353W"]}, "name": "TRR1", "id": "YDR353W"}, {"notes": {"original_bigg_ids": ["YHR106W"]}, "name": "TRR2", "id": "YHR106W"}, {"notes": {"original_bigg_ids": ["YMR261C"]}, "name": "TPS3", "id": "YMR261C"}, {"notes": {"original_bigg_ids": ["YBR126C"]}, "name": "TPS1", "id": "YBR126C"}, {"notes": {"original_bigg_ids": ["YML100W"]}, "name": "TSL1", "id": "YML100W"}, {"notes": {"original_bigg_ids": ["YDR074W"]}, "name": "TPS2", "id": "YDR074W"}, {"notes": {"original_bigg_ids": ["YDR001C"]}, "name": "NTH1", "id": "YDR001C"}, {"notes": {"original_bigg_ids": ["YBR001C"]}, "name": "NTH2", "id": "YBR001C"}, {"notes": {"original_bigg_ids": ["YPR026W"]}, "name": "ATH1", "id": "YPR026W"}, {"notes": {"original_bigg_ids": ["YJR078W"]}, "name": "BNA2", "id": "YJR078W"}, {"notes": {"original_bigg_ids": ["YGL026C"]}, "name": "TRP5", "id": "YGL026C"}, {"notes": {"original_bigg_ids": ["YOL097C"]}, "name": "WRS1", "id": "YOL097C"}, {"notes": {"original_bigg_ids": ["YDR268W"]}, "name": "MSW1", "id": "YDR268W"}, {"notes": {"original_bigg_ids": ["YGL202W"]}, "name": "ARO8", "id": "YGL202W"}, {"notes": {"original_bigg_ids": ["YGR185C"]}, "name": "TYS1", "id": "YGR185C"}, {"notes": {"original_bigg_ids": ["YPL097W"]}, "name": "MSY1", "id": "YPL097W"}, {"notes": {"original_bigg_ids": ["YDL103C"]}, "name": "QRI1", "id": "YDL103C"}, {"notes": {"original_bigg_ids": ["YBR019C"]}, "name": "GAL10", "id": "YBR019C"}, {"notes": {"original_bigg_ids": ["YIR032C"]}, "name": "DAL3", "id": "YIR032C"}, {"notes": {"original_bigg_ids": ["YKL024C"]}, "name": "URA6", "id": "YKL024C"}, {"notes": {"original_bigg_ids": ["YKR069W"]}, "name": "MET1", "id": "YKR069W"}, {"notes": {"original_bigg_ids": ["YOR278W"]}, "name": "HEM4", "id": "YOR278W"}, {"notes": {"original_bigg_ids": ["YDR047W"]}, "name": "HEM12", "id": "YDR047W"}, {"notes": {"original_bigg_ids": ["YHR128W"]}, "name": "FUR1", "id": "YHR128W"}, {"notes": {"original_bigg_ids": ["YBR021W"]}, "name": "FUR4", "id": "YBR021W"}, {"notes": {"original_bigg_ids": ["YHL016C"]}, "name": "DUR3", "id": "YHL016C"}, {"notes": {"original_bigg_ids": ["YBL042C"]}, "name": "FUI1", "id": "YBL042C"}, {"notes": {"original_bigg_ids": ["YGR094W"]}, "name": "VAS1", "id": "YGR094W"}, {"notes": {"original_bigg_ids": ["YJR133W"]}, "name": "XPT1", "id": "YJR133W"}, {"notes": {"original_bigg_ids": ["YGR194C"]}, "name": "XKS1", "id": "YGR194C"}, {"notes": {"original_bigg_ids": ["YLR070C"]}, "name": "XYL2", "id": "YLR070C"}, {"notes": {"original_bigg_ids": ["YNL292W"]}, "name": "PUS4", "id": "YNL292W"}, {"notes": {"original_bigg_ids": ["YFL001W"]}, "name": "DEG1", "id": "YFL001W"}, {"notes": {"original_bigg_ids": ["YGL063W"]}, "name": "PUS2", "id": "YGL063W"}, {"notes": {"original_bigg_ids": ["YPL212C"]}, "name": "PUS1", "id": "YPL212C"}, {"notes": {"original_bigg_ids": ["YER060W-A"]}, "name": "FCY22", "id": "YER060W_A"}, {"notes": {"original_bigg_ids": ["YCR024C-A"]}, "name": "PMP1", "id": "YCR024C_A"}, {"notes": {"original_bigg_ids": ["YEL017C-A"]}, "name": "PMP2", "id": "YEL017C_A"}, {"notes": {"original_bigg_ids": ["YHR039C-A"]}, "name": "VMA10", "id": "YHR039C_A"}, {"notes": {"original_bigg_ids": ["YML081C-A"]}, "name": "ATP18", "id": "YML081C_A"}, {"notes": {"original_bigg_ids": ["YOL077W-A"]}, "name": "ATP19", "id": "YOL077W_A"}, {"notes": {"original_bigg_ids": ["YDR322C-A"]}, "name": "TIM11", "id": "YDR322C_A"}, {"notes": {"original_bigg_ids": ["YHR001W-A"]}, "name": "QCR10", "id": "YHR001W_A"}, {"notes": {"original_bigg_ids": ["YCR073W-A"]}, "name": "SOL2", "id": "YCR073W_A"}], "compartments": {"c": "cytosol", "e": "extracellular space", "g": "golgi apparatus", "m": "mitochondria", "n": "nucleus", "r": "endoplasmic reticulum", "v": "vacuole", "x": "peroxisome/glyoxysome"}, "metabolites": [{"name": "L-Alanine", "notes": {"original_bigg_ids": ["ala_DASH_L_e"]}, "charge": 0, "formula": "C3H7NO2", "compartment": "e", "id": "ala__L_e"}, {"name": "Allantoin", "notes": {"original_bigg_ids": ["alltn_e"]}, "charge": 0, "formula": "C4H6N4O3", "compartment": "e", "id": "alltn_e"}, {"name": "Allantoate", "notes": {"original_bigg_ids": ["alltt_e"]}, "charge": 0, "formula": "C4H7N4O4", "compartment": "e", "id": "alltt_e"}, {"name": "S-Adenosyl-L-methionine", "notes": {"original_bigg_ids": ["amet_e"]}, "charge": 0, "formula": "C15H23N6O5S", "compartment": "e", "id": "amet_e"}, {"name": "D Arabinose C5H10O5", "notes": {"original_bigg_ids": ["arab_DASH_D_e"]}, "charge": 0, "formula": "C5H10O5", "compartment": "e", "id": "arab__D_e"}, {"name": "L-Arabinose", "notes": {"original_bigg_ids": ["arab_DASH_L_e"]}, "charge": 0, "formula": "C5H10O5", "compartment": "e", "id": "arab__L_e"}, {"name": "L-Arginine", "notes": {"original_bigg_ids": ["arg_DASH_L_e"]}, "charge": 0, "formula": "C6H15N4O2", "compartment": "e", "id": "arg__L_e"}, {"name": "L-Asparagine", "notes": {"original_bigg_ids": ["asn_DASH_L_e"]}, "charge": 0, "formula": "C4H8N2O3", "compartment": "e", "id": "asn__L_e"}, {"name": "L-Aspartate", "notes": {"original_bigg_ids": ["asp_DASH_L_e"]}, "charge": 0, "formula": "C4H6NO4", "compartment": "e", "id": "asp__L_e"}, {"name": "Biotin", "notes": {"original_bigg_ids": ["btn_e"]}, "charge": 0, "formula": "C10H15N2O3S", "compartment": "e", "id": "btn_e"}, {"name": "Choline", "notes": {"original_bigg_ids": ["chol_e"]}, "charge": 0, "formula": "C5H14NO", "compartment": "e", "id": "chol_e"}, {"name": "Citrate", "notes": {"original_bigg_ids": ["cit_e"]}, "charge": 0, "formula": "C6H5O7", "compartment": "e", "id": "cit_e"}, {"name": "CO2", "notes": {"original_bigg_ids": ["co2_e"]}, "charge": 0, "formula": "CO2", "compartment": "e", "id": "co2_e"}, {"name": "L-Carnitine", "notes": {"original_bigg_ids": ["crn_e"]}, "charge": 0, "formula": "C7H15NO3", "compartment": "e", "id": "crn_e"}, {"name": "Cytosine", "notes": {"original_bigg_ids": ["csn_e"]}, "charge": 0, "formula": "C4H5N3O", "compartment": "e", "id": "csn_e"}, {"name": "L-Cysteine", "notes": {"original_bigg_ids": ["cys_DASH_L_e"]}, "charge": 0, "formula": "C3H7NO2S", "compartment": "e", "id": "cys__L_e"}, {"name": "Cytidine", "notes": {"original_bigg_ids": ["cytd_e"]}, "charge": 0, "formula": "C9H13N3O5", "compartment": "e", "id": "cytd_e"}, {"name": "Deoxyadenosine", "notes": {"original_bigg_ids": ["dad_DASH_2_e"]}, "charge": 0, "formula": "C10H13N5O3", "compartment": "e", "id": "dad_2_e"}, {"name": "7,8-Diaminononanoate", "notes": {"original_bigg_ids": ["dann_e"]}, "charge": 0, "formula": "C9H21N2O2", "compartment": "e", "id": "dann_e"}, {"name": "Deoxycytidine", "notes": {"original_bigg_ids": ["dcyt_e"]}, "charge": 0, "formula": "C9H13N3O4", "compartment": "e", "id": "dcyt_e"}, {"name": "Deoxyguanosine", "notes": {"original_bigg_ids": ["dgsn_e"]}, "charge": 0, "formula": "C10H13N5O4", "compartment": "e", "id": "dgsn_e"}, {"name": "Deoxyinosine", "notes": {"original_bigg_ids": ["din_e"]}, "charge": 0, "formula": "C10H12N4O4", "compartment": "e", "id": "din_e"}, {"name": "DTTP", "notes": {"original_bigg_ids": ["dttp_e"]}, "charge": 0, "formula": "C10H13N2O14P3", "compartment": "e", "id": "dttp_e"}, {"name": "Deoxyuridine", "notes": {"original_bigg_ids": ["duri_e"]}, "charge": 0, "formula": "C9H12N2O5", "compartment": "e", "id": "duri_e"}, {"name": "Ergosterol C28H44O", "notes": {"original_bigg_ids": ["ergst_e"]}, "charge": 0, "formula": "C28H44O", "compartment": "e", "id": "ergst_e"}, {"name": "Ethanol", "notes": {"original_bigg_ids": ["etoh_e"]}, "charge": 0, "formula": "C2H6O", "compartment": "e", "id": "etoh_e"}, {"name": "FMN", "notes": {"original_bigg_ids": ["fmn_e"]}, "charge": 0, "formula": "C17H19N4O9P", "compartment": "e", "id": "fmn_e"}, {"name": "Formate", "notes": {"original_bigg_ids": ["for_e"]}, "charge": 0, "formula": "CH1O2", "compartment": "e", "id": "for_e"}, {"name": "D-Fructose", "notes": {"original_bigg_ids": ["fru_e"]}, "charge": 0, "formula": "C6H12O6", "compartment": "e", "id": "fru_e"}, {"name": "Fumarate", "notes": {"original_bigg_ids": ["fum_e"]}, "charge": 0, "formula": "C4H2O4", "compartment": "e", "id": "fum_e"}, {"name": "D-Galactose", "notes": {"original_bigg_ids": ["gal_e"]}, "charge": 0, "formula": "C6H12O6", "compartment": "e", "id": "gal_e"}, {"name": "D-Glucosamine 6-phosphate", "notes": {"original_bigg_ids": ["gam6p_e"]}, "charge": 0, "formula": "C6H13NO8P", "compartment": "e", "id": "gam6p_e"}, {"name": "Glycolaldehyde", "notes": {"original_bigg_ids": ["gcald_e"]}, "charge": 0, "formula": "C2H4O2", "compartment": "e", "id": "gcald_e"}, {"name": "D-Glucose", "notes": {"original_bigg_ids": ["glc_DASH_D_e"]}, "charge": 0, "formula": "C6H12O6", "compartment": "e", "id": "glc__D_e"}, {"name": "L-Glutamine", "notes": {"original_bigg_ids": ["gln_DASH_L_e"]}, "charge": 0, "formula": "C5H10N2O3", "compartment": "e", "id": "gln__L_e"}, {"name": "L-Glutamate", "notes": {"original_bigg_ids": ["glu_DASH_L_e"]}, "charge": 0, "formula": "C5H8NO4", "compartment": "e", "id": "glu__L_e"}, {"name": "Glycine", "notes": {"original_bigg_ids": ["gly_e"]}, "charge": 0, "formula": "C2H5NO2", "compartment": "e", "id": "gly_e"}, {"name": "Glycerol", "notes": {"original_bigg_ids": ["glyc_e"]}, "charge": 0, "formula": "C3H8O3", "compartment": "e", "id": "glyc_e"}, {"name": "Guanosine", "notes": {"original_bigg_ids": ["gsn_e"]}, "charge": 0, "formula": "C10H13N5O5", "compartment": "e", "id": "gsn_e"}, {"name": "Oxidized glutathione", "notes": {"original_bigg_ids": ["gthox_e"]}, "charge": 0, "formula": "C20H30N6O12S2", "compartment": "e", "id": "gthox_e"}, {"name": "Guanine", "notes": {"original_bigg_ids": ["gua_e"]}, "charge": 0, "formula": "C5H5N5O", "compartment": "e", "id": "gua_e"}, {"name": "H2O", "notes": {"original_bigg_ids": ["h2o_e"]}, "charge": 0, "formula": "H2O", "compartment": "e", "id": "h2o_e"}, {"name": "H+", "notes": {"original_bigg_ids": ["h_e"]}, "charge": 0, "formula": "H", "compartment": "e", "id": "h_e"}, {"name": "Hexadecanoate (n-C16:0)", "notes": {"original_bigg_ids": ["hdca_e"]}, "charge": 0, "formula": "C16H31O2", "compartment": "e", "id": "hdca_e"}, {"name": "Hexadecenoate (n-C16:1)", "notes": {"original_bigg_ids": ["hdcea_e"]}, "charge": 0, "formula": "C16H29O2", "compartment": "e", "id": "hdcea_e"}, {"name": "L-Histidine", "notes": {"original_bigg_ids": ["his_DASH_L_e"]}, "charge": 0, "formula": "C6H9N3O2", "compartment": "e", "id": "his__L_e"}, {"name": "Hypoxanthine", "notes": {"original_bigg_ids": ["hxan_e"]}, "charge": 0, "formula": "C5H4N4O", "compartment": "e", "id": "hxan_e"}, {"name": "L-Isoleucine", "notes": {"original_bigg_ids": ["ile_DASH_L_e"]}, "charge": 0, "formula": "C6H13NO2", "compartment": "e", "id": "ile__L_e"}, {"name": "Myo-Inositol", "notes": {"original_bigg_ids": ["inost_e"]}, "charge": 0, "formula": "C6H12O6", "compartment": "e", "id": "inost_e"}, {"name": "Inosine", "notes": {"original_bigg_ids": ["ins_e"]}, "charge": 0, "formula": "C10H12N4O5", "compartment": "e", "id": "ins_e"}, {"name": "Potassium", "notes": {"original_bigg_ids": ["k_e"]}, "charge": 0, "formula": "K", "compartment": "e", "id": "k_e"}, {"name": "L-Lactate", "notes": {"original_bigg_ids": ["lac_DASH_L_e"]}, "charge": 0, "formula": "C3H5O3", "compartment": "e", "id": "lac__L_e"}, {"name": "L-Leucine", "notes": {"original_bigg_ids": ["leu_DASH_L_e"]}, "charge": 0, "formula": "C6H13NO2", "compartment": "e", "id": "leu__L_e"}, {"name": "L-Lysine", "notes": {"original_bigg_ids": ["lys_DASH_L_e"]}, "charge": 0, "formula": "C6H15N2O2", "compartment": "e", "id": "lys__L_e"}, {"name": "L-Malate", "notes": {"original_bigg_ids": ["mal_DASH_L_e"]}, "charge": 0, "formula": "C4H4O5", "compartment": "e", "id": "mal__L_e"}, {"name": "Maltose", "notes": {"original_bigg_ids": ["malt_e"]}, "charge": 0, "formula": "C12H22O11", "compartment": "e", "id": "malt_e"}, {"name": "D-Mannose", "notes": {"original_bigg_ids": ["man_e"]}, "charge": 0, "formula": "C6H12O6", "compartment": "e", "id": "man_e"}, {"name": "Melibiose", "notes": {"original_bigg_ids": ["melib_e"]}, "charge": 0, "formula": "C12H22O11", "compartment": "e", "id": "melib_e"}, {"name": "L-Methionine", "notes": {"original_bigg_ids": ["met_DASH_L_e"]}, "charge": 0, "formula": "C5H11NO2S", "compartment": "e", "id": "met__L_e"}, {"name": "S-Methyl-L-methionine", "notes": {"original_bigg_ids": ["mmet_e"]}, "charge": 0, "formula": "C6H14NO2S", "compartment": "e", "id": "mmet_e"}, {"name": "Sodium", "notes": {"original_bigg_ids": ["na1_e"]}, "charge": 0, "formula": "Na", "compartment": "e", "id": "na1_e"}, {"name": "Ammonium", "notes": {"original_bigg_ids": ["nh4_e"]}, "charge": 0, "formula": "H4N", "compartment": "e", "id": "nh4_e"}, {"name": "NMN", "notes": {"original_bigg_ids": ["nmn_e"]}, "charge": 0, "formula": "C11H14N2O8P", "compartment": "e", "id": "nmn_e"}, {"name": "O2", "notes": {"original_bigg_ids": ["o2_e"]}, "charge": 0, "formula": "O2", "compartment": "e", "id": "o2_e"}, {"name": "Octadecanoate (n-C18:0)", "notes": {"original_bigg_ids": ["ocdca_e"]}, "charge": 0, "formula": "C18H35O2", "compartment": "e", "id": "ocdca_e"}, {"name": "Octadecenoate (n-C18:1)", "notes": {"original_bigg_ids": ["ocdcea_e"]}, "charge": 0, "formula": "C18H33O2", "compartment": "e", "id": "ocdcea_e"}, {"name": "Octadecadienoate n C182 C18H31O2", "notes": {"original_bigg_ids": ["ocdcya_e"]}, "charge": 0, "formula": "C18H31O2", "compartment": "e", "id": "ocdcya_e"}, {"name": "Ornithine", "notes": {"original_bigg_ids": ["orn_e"]}, "charge": 0, "formula": "C5H13N2O2", "compartment": "e", "id": "orn_e"}, {"name": "Adenosine 3',5'-bisphosphate", "notes": {"original_bigg_ids": ["pap_e"]}, "charge": 0, "formula": "C10H11N5O10P2", "compartment": "e", "id": "pap_e"}, {"name": "Peptide C2H4NO2RC2H2NOR", "notes": {"original_bigg_ids": ["pepd_e"]}, "charge": 0, "formula": "C2H4NO2RC2H2NOR", "compartment": "e", "id": "pepd_e"}, {"name": "L-Phenylalanine", "notes": {"original_bigg_ids": ["phe_DASH_L_e"]}, "charge": 0, "formula": "C9H11NO2", "compartment": "e", "id": "phe__L_e"}, {"name": "Phosphate", "notes": {"original_bigg_ids": ["pi_e"]}, "charge": 0, "formula": "HO4P", "compartment": "e", "id": "pi_e"}, {"name": "(R)-Pantothenate", "notes": {"original_bigg_ids": ["pnto_DASH_R_e"]}, "charge": 0, "formula": "C9H16NO5", "compartment": "e", "id": "pnto__R_e"}, {"name": "L-Proline", "notes": {"original_bigg_ids": ["pro_DASH_L_e"]}, "charge": 0, "formula": "C5H9NO2", "compartment": "e", "id": "pro__L_e"}, {"name": "Putrescine", "notes": {"original_bigg_ids": ["ptrc_e"]}, "charge": 0, "formula": "C4H14N2", "compartment": "e", "id": "ptrc_e"}, {"name": "Pyruvate", "notes": {"original_bigg_ids": ["pyr_e"]}, "charge": 0, "formula": "C3H3O3", "compartment": "e", "id": "pyr_e"}, {"name": "D-Ribose", "notes": {"original_bigg_ids": ["rib_DASH_D_e"]}, "charge": 0, "formula": "C5H10O5", "compartment": "e", "id": "rib__D_e"}, {"name": "Riboflavin", "notes": {"original_bigg_ids": ["ribflv_e"]}, "charge": 0, "formula": "C17H20N4O6", "compartment": "e", "id": "ribflv_e"}, {"name": "D-Sorbitol", "notes": {"original_bigg_ids": ["sbt_DASH_D_e"]}, "charge": 0, "formula": "C6H14O6", "compartment": "e", "id": "sbt__D_e"}, {"name": "L Sorbitol C6H14O6", "notes": {"original_bigg_ids": ["sbt_DASH_L_e"]}, "charge": 0, "formula": "C6H14O6", "compartment": "e", "id": "sbt__L_e"}, {"name": "L-Serine", "notes": {"original_bigg_ids": ["ser_DASH_L_e"]}, "charge": 0, "formula": "C3H7NO3", "compartment": "e", "id": "ser__L_e"}, {"name": "Sulfate", "notes": {"original_bigg_ids": ["so4_e"]}, "charge": 0, "formula": "O4S", "compartment": "e", "id": "so4_e"}, {"name": "Spermidine", "notes": {"original_bigg_ids": ["spmd_e"]}, "charge": 0, "formula": "C7H22N3", "compartment": "e", "id": "spmd_e"}, {"name": "Spermine C10H30N4", "notes": {"original_bigg_ids": ["sprm_e"]}, "charge": 0, "formula": "C10H30N4", "compartment": "e", "id": "sprm_e"}, {"name": "L Sorbose C6H12O6", "notes": {"original_bigg_ids": ["srb_DASH_L_e"]}, "charge": 0, "formula": "C6H12O6", "compartment": "e", "id": "srb__L_e"}, {"name": "Succinate", "notes": {"original_bigg_ids": ["succ_e"]}, "charge": 0, "formula": "C4H4O4", "compartment": "e", "id": "succ_e"}, {"name": "Sucrose", "notes": {"original_bigg_ids": ["sucr_e"]}, "charge": 0, "formula": "C12H22O11", "compartment": "e", "id": "sucr_e"}, {"name": "Thiamin", "notes": {"original_bigg_ids": ["thm_e"]}, "charge": 0, "formula": "C12H17N4OS", "compartment": "e", "id": "thm_e"}, {"name": "Thiamin monophosphate", "notes": {"original_bigg_ids": ["thmmp_e"]}, "charge": 0, "formula": "C12H16N4O4PS", "compartment": "e", "id": "thmmp_e"}, {"name": "Thiamine diphosphate", "notes": {"original_bigg_ids": ["thmpp_e"]}, "charge": 0, "formula": "C12H16N4O7P2S", "compartment": "e", "id": "thmpp_e"}, {"name": "L-Threonine", "notes": {"original_bigg_ids": ["thr_DASH_L_e"]}, "charge": 0, "formula": "C4H9NO3", "compartment": "e", "id": "thr__L_e"}, {"name": "Thymine", "notes": {"original_bigg_ids": ["thym_e"]}, "charge": 0, "formula": "C5H6N2O2", "compartment": "e", "id": "thym_e"}, {"name": "Thymidine", "notes": {"original_bigg_ids": ["thymd_e"]}, "charge": 0, "formula": "C10H14N2O5", "compartment": "e", "id": "thymd_e"}, {"name": "Trehalose", "notes": {"original_bigg_ids": ["tre_e"]}, "charge": 0, "formula": "C12H22O11", "compartment": "e", "id": "tre_e"}, {"name": "L-Tryptophan", "notes": {"original_bigg_ids": ["trp_DASH_L_e"]}, "charge": 0, "formula": "C11H12N2O2", "compartment": "e", "id": "trp__L_e"}, {"name": "Tetradecanoate (n-C14:0)", "notes": {"original_bigg_ids": ["ttdca_e"]}, "charge": 0, "formula": "C14H27O2", "compartment": "e", "id": "ttdca_e"}, {"name": "L-Tyrosine", "notes": {"original_bigg_ids": ["tyr_DASH_L_e"]}, "charge": 0, "formula": "C9H11NO3", "compartment": "e", "id": "tyr__L_e"}, {"name": "Uracil", "notes": {"original_bigg_ids": ["ura_e"]}, "charge": 0, "formula": "C4H4N2O2", "compartment": "e", "id": "ura_e"}, {"name": "Urea", "notes": {"original_bigg_ids": ["urea_e"]}, "charge": 0, "formula": "CH4N2O", "compartment": "e", "id": "urea_e"}, {"name": "Uridine", "notes": {"original_bigg_ids": ["uri_e"]}, "charge": 0, "formula": "C9H12N2O6", "compartment": "e", "id": "uri_e"}, {"name": "L-Valine", "notes": {"original_bigg_ids": ["val_DASH_L_e"]}, "charge": 0, "formula": "C5H11NO2", "compartment": "e", "id": "val__L_e"}, {"name": "Xanthine", "notes": {"original_bigg_ids": ["xan_e"]}, "charge": 0, "formula": "C5H4N4O2", "compartment": "e", "id": "xan_e"}, {"name": "Xanthosine", "notes": {"original_bigg_ids": ["xtsn_e"]}, "charge": 0, "formula": "C10H12N4O6", "compartment": "e", "id": "xtsn_e"}, {"name": "D-Xylose", "notes": {"original_bigg_ids": ["xyl_DASH_D_e"]}, "charge": 0, "formula": "C5H10O5", "compartment": "e", "id": "xyl__D_e"}, {"name": "Xylitol C5H12O5", "notes": {"original_bigg_ids": ["xylt_e"]}, "charge": 0, "formula": "C5H12O5", "compartment": "e", "id": "xylt_e"}, {"name": "Zymosterol C27H44O", "notes": {"original_bigg_ids": ["zymst_e"]}, "charge": 0, "formula": "C27H44O", "compartment": "e", "id": "zymst_e"}, {"name": "Decanoate (n-C10:0)", "notes": {"original_bigg_ids": ["dca_x"]}, "charge": 0, "formula": "C10H19O2", "compartment": "x", "id": "dca_x"}, {"name": "Decanoate (n-C10:0)", "notes": {"original_bigg_ids": ["dca_c"]}, "charge": 0, "formula": "C10H19O2", "compartment": "c", "id": "dca_c"}, {"name": "H2O", "notes": {"original_bigg_ids": ["h2o_c"]}, "charge": 0, "formula": "H2O", "compartment": "c", "id": "h2o_c"}, {"name": "Dodecanoate (n-C12:0)", "notes": {"original_bigg_ids": ["ddca_c"]}, "charge": 0, "formula": "C12H23O2", "compartment": "c", "id": "ddca_c"}, {"name": "Dodecanoyl-ACP (n-C12:0ACP)", "notes": {"original_bigg_ids": ["ddcaACP_c"]}, "charge": 0, "formula": "C23H43N2O8PRS", "compartment": "c", "id": "ddcaACP_c"}, {"name": "H+", "notes": {"original_bigg_ids": ["h_c"]}, "charge": 0, "formula": "H", "compartment": "c", "id": "h_c"}, {"name": "Acyl carrier protein", "notes": {"original_bigg_ids": ["ACP_c"]}, "charge": 0, "formula": "C11H21N2O7PRS", "compartment": "c", "id": "ACP_c"}, {"name": "Dodecanoyl-ACP (n-C12:0ACP)", "notes": {"original_bigg_ids": ["ddcaACP_m"]}, "charge": 0, "formula": "C23H43N2O8PRS", "compartment": "m", "id": "ddcaACP_m"}, {"name": "Dodecanoate (n-C12:0)", "notes": {"original_bigg_ids": ["ddca_x"]}, "charge": 0, "formula": "C12H23O2", "compartment": "x", "id": "ddca_x"}, {"name": "Myristoyl-ACP (n-C14:0ACP)", "notes": {"original_bigg_ids": ["myrsACP_c"]}, "charge": 0, "formula": "C25H47N2O8PRS", "compartment": "c", "id": "myrsACP_c"}, {"name": "Tetradecanoate (n-C14:0)", "notes": {"original_bigg_ids": ["ttdca_c"]}, "charge": 0, "formula": "C14H27O2", "compartment": "c", "id": "ttdca_c"}, {"name": "Myristoyl-ACP (n-C14:0ACP)", "notes": {"original_bigg_ids": ["myrsACP_m"]}, "charge": 0, "formula": "C25H47N2O8PRS", "compartment": "m", "id": "myrsACP_m"}, {"name": "ADP", "notes": {"original_bigg_ids": ["adp_x"]}, "charge": 0, "formula": "C10H12N5O10P2", "compartment": "x", "id": "adp_x"}, {"name": "Tetradecanoyl-CoA (n-C14:0CoA)", "notes": {"original_bigg_ids": ["tdcoa_x"]}, "charge": 0, "formula": "C35H58N7O17P3S", "compartment": "x", "id": "tdcoa_x"}, {"name": "H+", "notes": {"original_bigg_ids": ["h_x"]}, "charge": 0, "formula": "H", "compartment": "x", "id": "h_x"}, {"name": "H2O", "notes": {"original_bigg_ids": ["h2o_x"]}, "charge": 0, "formula": "H2O", "compartment": "x", "id": "h2o_x"}, {"name": "Tetradecanoyl-CoA (n-C14:0CoA)", "notes": {"original_bigg_ids": ["tdcoa_c"]}, "charge": 0, "formula": "C35H58N7O17P3S", "compartment": "c", "id": "tdcoa_c"}, {"name": "Phosphate", "notes": {"original_bigg_ids": ["pi_x"]}, "charge": 0, "formula": "HO4P", "compartment": "x", "id": "pi_x"}, {"name": "ATP", "notes": {"original_bigg_ids": ["atp_x"]}, "charge": 0, "formula": "C10H12N5O13P3", "compartment": "x", "id": "atp_x"}, {"name": "Tetradecanoate (n-C14:0)", "notes": {"original_bigg_ids": ["ttdca_x"]}, "charge": 0, "formula": "C14H27O2", "compartment": "x", "id": "ttdca_x"}, {"name": "Cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)", "notes": {"original_bigg_ids": ["tdeACP_c"]}, "charge": 0, "formula": "C25H45N2O8PRS", "compartment": "c", "id": "tdeACP_c"}, {"name": "Tetradecenoate (n-C14:1)", "notes": {"original_bigg_ids": ["ttdcea_c"]}, "charge": 0, "formula": "C14H25O2", "compartment": "c", "id": "ttdcea_c"}, {"name": "Cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)", "notes": {"original_bigg_ids": ["tdeACP_m"]}, "charge": 0, "formula": "C25H45N2O8PRS", "compartment": "m", "id": "tdeACP_m"}, {"name": "Tetradecenoyl-CoA (n-C14:1CoA)", "notes": {"original_bigg_ids": ["tdecoa_c"]}, "charge": 0, "formula": "C35H56N7O17P3S", "compartment": "c", "id": "tdecoa_c"}, {"name": "Tetradecenoyl-CoA (n-C14:1CoA)", "notes": {"original_bigg_ids": ["tdecoa_x"]}, "charge": 0, "formula": "C35H56N7O17P3S", "compartment": "x", "id": "tdecoa_x"}, {"name": "Tetradecenoate (n-C14:1)", "notes": {"original_bigg_ids": ["ttdcea_x"]}, "charge": 0, "formula": "C14H25O2", "compartment": "x", "id": "ttdcea_x"}, {"name": "Palmitoyl-ACP (n-C16:0ACP)", "notes": {"original_bigg_ids": ["palmACP_c"]}, "charge": 0, "formula": "C27H51N2O8PRS", "compartment": "c", "id": "palmACP_c"}, {"name": "Hexadecanoate (n-C16:0)", "notes": {"original_bigg_ids": ["hdca_c"]}, "charge": 0, "formula": "C16H31O2", "compartment": "c", "id": "hdca_c"}, {"name": "Palmitoyl-ACP (n-C16:0ACP)", "notes": {"original_bigg_ids": ["palmACP_m"]}, "charge": 0, "formula": "C27H51N2O8PRS", "compartment": "m", "id": "palmACP_m"}, {"name": "Palmitoyl-CoA (n-C16:0CoA)", "notes": {"original_bigg_ids": ["pmtcoa_c"]}, "charge": 0, "formula": "C37H62N7O17P3S", "compartment": "c", "id": "pmtcoa_c"}, {"name": "Palmitoyl-CoA (n-C16:0CoA)", "notes": {"original_bigg_ids": ["pmtcoa_x"]}, "charge": 0, "formula": "C37H62N7O17P3S", "compartment": "x", "id": "pmtcoa_x"}, {"name": "Hexadecanoate (n-C16:0)", "notes": {"original_bigg_ids": ["hdca_x"]}, "charge": 0, "formula": "C16H31O2", "compartment": "x", "id": "hdca_x"}, {"name": "Cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)", "notes": {"original_bigg_ids": ["hdeACP_c"]}, "charge": 0, "formula": "C27H49N2O8PRS", "compartment": "c", "id": "hdeACP_c"}, {"name": "Hexadecenoate (n-C16:1)", "notes": {"original_bigg_ids": ["hdcea_c"]}, "charge": 0, "formula": "C16H29O2", "compartment": "c", "id": "hdcea_c"}, {"name": "Cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)", "notes": {"original_bigg_ids": ["hdeACP_m"]}, "charge": 0, "formula": "C27H49N2O8PRS", "compartment": "m", "id": "hdeACP_m"}, {"name": "Hexadecenoyl-CoA (n-C16:1CoA)", "notes": {"original_bigg_ids": ["hdcoa_x"]}, "charge": 0, "formula": "C37H60N7O17P3S", "compartment": "x", "id": "hdcoa_x"}, {"name": "Hexadecenoyl-CoA (n-C16:1CoA)", "notes": {"original_bigg_ids": ["hdcoa_c"]}, "charge": 0, "formula": "C37H60N7O17P3S", "compartment": "c", "id": "hdcoa_c"}, {"name": "Hexadecenoate (n-C16:1)", "notes": {"original_bigg_ids": ["hdcea_x"]}, "charge": 0, "formula": "C16H29O2", "compartment": "x", "id": "hdcea_x"}, {"name": "Octadecanoate (n-C18:0)", "notes": {"original_bigg_ids": ["ocdca_c"]}, "charge": 0, "formula": "C18H35O2", "compartment": "c", "id": "ocdca_c"}, {"name": "Octadecanoyl-ACP (n-C18:0ACP)", "notes": {"original_bigg_ids": ["ocdcaACP_c"]}, "charge": 0, "formula": "C29H55N2O8PRS", "compartment": "c", "id": "ocdcaACP_c"}, {"name": "Octadecanoyl-ACP (n-C18:0ACP)", "notes": {"original_bigg_ids": ["ocdcaACP_m"]}, "charge": 0, "formula": "C29H55N2O8PRS", "compartment": "m", "id": "ocdcaACP_m"}, {"name": "Stearoyl-CoA (n-C18:0CoA)", "notes": {"original_bigg_ids": ["stcoa_c"]}, "charge": 0, "formula": "C39H66N7O17P3S", "compartment": "c", "id": "stcoa_c"}, {"name": "Stearoyl-CoA (n-C18:0CoA)", "notes": {"original_bigg_ids": ["stcoa_x"]}, "charge": 0, "formula": "C39H66N7O17P3S", "compartment": "x", "id": "stcoa_x"}, {"name": "Cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)", "notes": {"original_bigg_ids": ["octeACP_c"]}, "charge": 0, "formula": "C29H53N2O8PRS", "compartment": "c", "id": "octeACP_c"}, {"name": "Octadecenoate (n-C18:1)", "notes": {"original_bigg_ids": ["ocdcea_c"]}, "charge": 0, "formula": "C18H33O2", "compartment": "c", "id": "ocdcea_c"}, {"name": "Cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)", "notes": {"original_bigg_ids": ["octeACP_m"]}, "charge": 0, "formula": "C29H53N2O8PRS", "compartment": "m", "id": "octeACP_m"}, {"name": "Octadecenoyl-CoA (n-C18:1CoA)", "notes": {"original_bigg_ids": ["odecoa_x"]}, "charge": 0, "formula": "C39H64N7O17P3S", "compartment": "x", "id": "odecoa_x"}, {"name": "Octadecenoyl-CoA (n-C18:1CoA)", "notes": {"original_bigg_ids": ["odecoa_c"]}, "charge": 0, "formula": "C39H64N7O17P3S", "compartment": "c", "id": "odecoa_c"}, {"name": "Octadecynoyl ACP n C182ACP C29H51N2O8PRS", "notes": {"original_bigg_ids": ["ocdcyaACP_c"]}, "charge": 0, "formula": "C29H51N2O8PRS", "compartment": "c", "id": "ocdcyaACP_c"}, {"name": "Octadecadienoate n C182 C18H31O2", "notes": {"original_bigg_ids": ["ocdcya_c"]}, "charge": 0, "formula": "C18H31O2", "compartment": "c", "id": "ocdcya_c"}, {"name": "Octadecynoyl ACP n C182ACP C29H51N2O8PRS", "notes": {"original_bigg_ids": ["ocdcyaACP_m"]}, "charge": 0, "formula": "C29H51N2O8PRS", "compartment": "m", "id": "ocdcyaACP_m"}, {"name": "Isopentenyl diphosphate", "notes": {"original_bigg_ids": ["ipdp_c"]}, "charge": 0, "formula": "C5H9O7P2", "compartment": "c", "id": "ipdp_c"}, {"name": "Dimethylallyl diphosphate", "notes": {"original_bigg_ids": ["dmpp_c"]}, "charge": 0, "formula": "C5H9O7P2", "compartment": "c", "id": "dmpp_c"}, {"name": "N-Acetyl-D-glucosamine 6-phosphate", "notes": {"original_bigg_ids": ["acgam6p_c"]}, "charge": 0, "formula": "C8H14NO9P", "compartment": "c", "id": "acgam6p_c"}, {"name": "N-Acetyl-D-glucosamine 1-phosphate", "notes": {"original_bigg_ids": ["acgam1p_c"]}, "charge": 0, "formula": "C8H14NO9P", "compartment": "c", "id": "acgam1p_c"}, {"name": "ADP", "notes": {"original_bigg_ids": ["adp_m"]}, "charge": 0, "formula": "C10H12N5O10P2", "compartment": "m", "id": "adp_m"}, {"name": "ATP", "notes": {"original_bigg_ids": ["atp_m"]}, "charge": 0, "formula": "C10H12N5O13P3", "compartment": "m", "id": "atp_m"}, {"name": "N-Acetyl-L-glutamate", "notes": {"original_bigg_ids": ["acglu_m"]}, "charge": 0, "formula": "C7H9NO5", "compartment": "m", "id": "acglu_m"}, {"name": "N-Acetyl-L-glutamyl 5-phosphate", "notes": {"original_bigg_ids": ["acg5p_m"]}, "charge": 0, "formula": "C7H9NO8P", "compartment": "m", "id": "acg5p_m"}, {"name": "H+", "notes": {"original_bigg_ids": ["h_m"]}, "charge": 0, "formula": "H", "compartment": "m", "id": "h_m"}, {"name": "Coenzyme A", "notes": {"original_bigg_ids": ["coa_m"]}, "charge": 0, "formula": "C21H32N7O16P3S", "compartment": "m", "id": "coa_m"}, {"name": "Acetyl-CoA", "notes": {"original_bigg_ids": ["accoa_m"]}, "charge": 0, "formula": "C23H34N7O17P3S", "compartment": "m", "id": "accoa_m"}, {"name": "L-Glutamate", "notes": {"original_bigg_ids": ["glu_DASH_L_m"]}, "charge": 0, "formula": "C5H8NO4", "compartment": "m", "id": "glu__L_m"}, {"name": "Pyruvate", "notes": {"original_bigg_ids": ["pyr_m"]}, "charge": 0, "formula": "C3H3O3", "compartment": "m", "id": "pyr_m"}, {"name": "2-Oxobutanoate", "notes": {"original_bigg_ids": ["2obut_m"]}, "charge": 0, "formula": "C4H5O3", "compartment": "m", "id": "2obut_m"}, {"name": "CO2", "notes": {"original_bigg_ids": ["co2_m"]}, "charge": 0, "formula": "CO2", "compartment": "m", "id": "co2_m"}, {"name": "(S)-2-Aceto-2-hydroxybutanoate", "notes": {"original_bigg_ids": ["2ahbut_m"]}, "charge": 0, "formula": "C6H9O4", "compartment": "m", "id": "2ahbut_m"}, {"name": "(S)-2-Acetolactate", "notes": {"original_bigg_ids": ["alac_DASH_S_m"]}, "charge": 0, "formula": "C5H7O4", "compartment": "m", "id": "alac__S_m"}, {"name": "Acetyl-CoA", "notes": {"original_bigg_ids": ["accoa_c"]}, "charge": 0, "formula": "C23H34N7O17P3S", "compartment": "c", "id": "accoa_c"}, {"name": "Acetate", "notes": {"original_bigg_ids": ["ac_c"]}, "charge": 0, "formula": "C2H3O2", "compartment": "c", "id": "ac_c"}, {"name": "Coenzyme A", "notes": {"original_bigg_ids": ["coa_c"]}, "charge": 0, "formula": "C21H32N7O16P3S", "compartment": "c", "id": "coa_c"}, {"name": "Hydrogen peroxide", "notes": {"original_bigg_ids": ["h2o2_x"]}, "charge": 0, "formula": "H2O2", "compartment": "x", "id": "h2o2_x"}, {"name": "O2", "notes": {"original_bigg_ids": ["o2_x"]}, "charge": 0, "formula": "O2", "compartment": "x", "id": "o2_x"}, {"name": "Decanoyl-CoA (n-C10:0CoA)", "notes": {"original_bigg_ids": ["dcacoa_x"]}, "charge": 0, "formula": "C31H50N7O17P3S", "compartment": "x", "id": "dcacoa_x"}, {"name": "Trans-Dec-2-enoyl-CoA", "notes": {"original_bigg_ids": ["dc2coa_x"]}, "charge": 0, "formula": "C31H48N7O17P3S", "compartment": "x", "id": "dc2coa_x"}, {"name": "Dodecanoyl-CoA (n-C12:0CoA)", "notes": {"original_bigg_ids": ["ddcacoa_x"]}, "charge": 0, "formula": "C33H54N7O17P3S", "compartment": "x", "id": "ddcacoa_x"}, {"name": "Trans-Dodec-2-enoyl-CoA", "notes": {"original_bigg_ids": ["dd2coa_x"]}, "charge": 0, "formula": "C33H52N7O17P3S", "compartment": "x", "id": "dd2coa_x"}, {"name": "Trans-Tetradec-2-enoyl-CoA", "notes": {"original_bigg_ids": ["td2coa_x"]}, "charge": 0, "formula": "C35H56N7O17P3S", "compartment": "x", "id": "td2coa_x"}, {"name": "Trans-Hexadec-2-enoyl-CoA", "notes": {"original_bigg_ids": ["hdd2coa_x"]}, "charge": 0, "formula": "C37H60N7O17P3S", "compartment": "x", "id": "hdd2coa_x"}, {"name": "Trans-Octadec-2-enoyl-CoA", "notes": {"original_bigg_ids": ["od2coa_x"]}, "charge": 0, "formula": "C39H64N7O17P3S", "compartment": "x", "id": "od2coa_x"}, {"name": "Hexacosanoyl CoA n C260CoA C47H82N7O17P3S", "notes": {"original_bigg_ids": ["hexccoa_x"]}, "charge": 0, "formula": "C47H82N7O17P3S", "compartment": "x", "id": "hexccoa_x"}, {"name": "Trans Hexacos 2 enoyl CoA C47H80N7O17P3S", "notes": {"original_bigg_ids": ["hxc2coa_x"]}, "charge": 0, "formula": "C47H80N7O17P3S", "compartment": "x", "id": "hxc2coa_x"}, {"name": "Acetyl-ACP", "notes": {"original_bigg_ids": ["acACP_c"]}, "charge": 0, "formula": "C13H23N2O8PRS", "compartment": "c", "id": "acACP_c"}, {"name": "Acyl carrier protein", "notes": {"original_bigg_ids": ["ACP_m"]}, "charge": 0, "formula": "C11H21N2O7PRS", "compartment": "m", "id": "ACP_m"}, {"name": "Acetyl-ACP", "notes": {"original_bigg_ids": ["acACP_m"]}, "charge": 0, "formula": "C13H23N2O8PRS", "compartment": "m", "id": "acACP_m"}, {"name": "Citrate", "notes": {"original_bigg_ids": ["cit_c"]}, "charge": 0, "formula": "C6H5O7", "compartment": "c", "id": "cit_c"}, {"name": "Isocitrate", "notes": {"original_bigg_ids": ["icit_c"]}, "charge": 0, "formula": "C6H5O7", "compartment": "c", "id": "icit_c"}, {"name": "Citrate", "notes": {"original_bigg_ids": ["cit_m"]}, "charge": 0, "formula": "C6H5O7", "compartment": "m", "id": "cit_m"}, {"name": "Isocitrate", "notes": {"original_bigg_ids": ["icit_m"]}, "charge": 0, "formula": "C6H5O7", "compartment": "m", "id": "icit_m"}, {"name": "N2-Acetyl-L-ornithine", "notes": {"original_bigg_ids": ["acorn_m"]}, "charge": 0, "formula": "C7H14N2O3", "compartment": "m", "id": "acorn_m"}, {"name": "2-Oxoglutarate", "notes": {"original_bigg_ids": ["akg_m"]}, "charge": 0, "formula": "C5H4O5", "compartment": "m", "id": "akg_m"}, {"name": "N-Acetyl-L-glutamate 5-semialdehyde", "notes": {"original_bigg_ids": ["acg5sa_m"]}, "charge": 0, "formula": "C7H10NO4", "compartment": "m", "id": "acg5sa_m"}, {"name": "Adenosine 3',5'-bisphosphate", "notes": {"original_bigg_ids": ["pap_m"]}, "charge": 0, "formula": "C10H11N5O10P2", "compartment": "m", "id": "pap_m"}, {"name": "Pantetheine 4'-phosphate", "notes": {"original_bigg_ids": ["pan4p_m"]}, "charge": 0, "formula": "C11H21N2O7PS", "compartment": "m", "id": "pan4p_m"}, {"name": "H2O", "notes": {"original_bigg_ids": ["h2o_m"]}, "charge": 0, "formula": "H2O", "compartment": "m", "id": "h2o_m"}, {"name": "O Acetylcarnitine C9H17NO4", "notes": {"original_bigg_ids": ["acrn_c"]}, "charge": 0, "formula": "C9H17NO4", "compartment": "c", "id": "acrn_c"}, {"name": "O Acetylcarnitine C9H17NO4", "notes": {"original_bigg_ids": ["acrn_m"]}, "charge": 0, "formula": "C9H17NO4", "compartment": "m", "id": "acrn_m"}, {"name": "O Acetylcarnitine C9H17NO4", "notes": {"original_bigg_ids": ["acrn_x"]}, "charge": 0, "formula": "C9H17NO4", "compartment": "x", "id": "acrn_x"}, {"name": "ATP", "notes": {"original_bigg_ids": ["atp_c"]}, "charge": 0, "formula": "C10H12N5O13P3", "compartment": "c", "id": "atp_c"}, {"name": "Diphosphate", "notes": {"original_bigg_ids": ["ppi_c"]}, "charge": 0, "formula": "HO7P2", "compartment": "c", "id": "ppi_c"}, {"name": "AMP", "notes": {"original_bigg_ids": ["amp_c"]}, "charge": 0, "formula": "C10H12N5O7P", "compartment": "c", "id": "amp_c"}, {"name": "Diphosphate", "notes": {"original_bigg_ids": ["ppi_m"]}, "charge": 0, "formula": "HO7P2", "compartment": "m", "id": "ppi_m"}, {"name": "AMP", "notes": {"original_bigg_ids": ["amp_m"]}, "charge": 0, "formula": "C10H12N5O7P", "compartment": "m", "id": "amp_m"}, {"name": "Acetate", "notes": {"original_bigg_ids": ["ac_m"]}, "charge": 0, "formula": "C2H3O2", "compartment": "m", "id": "ac_m"}, {"name": "AMP", "notes": {"original_bigg_ids": ["amp_x"]}, "charge": 0, "formula": "C10H12N5O7P", "compartment": "x", "id": "amp_x"}, {"name": "Coenzyme A", "notes": {"original_bigg_ids": ["coa_x"]}, "charge": 0, "formula": "C21H32N7O16P3S", "compartment": "x", "id": "coa_x"}, {"name": "Acetyl-CoA", "notes": {"original_bigg_ids": ["accoa_x"]}, "charge": 0, "formula": "C23H34N7O17P3S", "compartment": "x", "id": "accoa_x"}, {"name": "Acetate", "notes": {"original_bigg_ids": ["ac_x"]}, "charge": 0, "formula": "C2H3O2", "compartment": "x", "id": "ac_x"}, {"name": "Diphosphate", "notes": {"original_bigg_ids": ["ppi_x"]}, "charge": 0, "formula": "HO7P2", "compartment": "x", "id": "ppi_x"}, {"name": "Acetate", "notes": {"original_bigg_ids": ["ac_e"]}, "charge": 0, "formula": "C2H3O2", "compartment": "e", "id": "ac_e"}, {"name": "Inosine", "notes": {"original_bigg_ids": ["ins_c"]}, "charge": 0, "formula": "C10H12N4O5", "compartment": "c", "id": "ins_c"}, {"name": "Ammonium", "notes": {"original_bigg_ids": ["nh4_c"]}, "charge": 0, "formula": "H4N", "compartment": "c", "id": "nh4_c"}, {"name": "Adenosine", "notes": {"original_bigg_ids": ["adn_c"]}, "charge": 0, "formula": "C10H13N5O4", "compartment": "c", "id": "adn_c"}, {"name": "4-Aminobenzoate", "notes": {"original_bigg_ids": ["4abz_c"]}, "charge": 0, "formula": "C7H6NO2", "compartment": "c", "id": "4abz_c"}, {"name": "4-amino-4-deoxychorismate", "notes": {"original_bigg_ids": ["4adcho_c"]}, "charge": 0, "formula": "C10H10NO5", "compartment": "c", "id": "4adcho_c"}, {"name": "Pyruvate", "notes": {"original_bigg_ids": ["pyr_c"]}, "charge": 0, "formula": "C3H3O3", "compartment": "c", "id": "pyr_c"}, {"name": "Chorismate", "notes": {"original_bigg_ids": ["chor_c"]}, "charge": 0, "formula": "C10H8O6", "compartment": "c", "id": "chor_c"}, {"name": "L-Glutamine", "notes": {"original_bigg_ids": ["gln_DASH_L_c"]}, "charge": 0, "formula": "C5H10N2O3", "compartment": "c", "id": "gln__L_c"}, {"name": "L-Glutamate", "notes": {"original_bigg_ids": ["glu_DASH_L_c"]}, "charge": 0, "formula": "C5H8NO4", "compartment": "c", "id": "glu__L_c"}, {"name": "Hypoxanthine", "notes": {"original_bigg_ids": ["hxan_c"]}, "charge": 0, "formula": "C5H4N4O", "compartment": "c", "id": "hxan_c"}, {"name": "Adenine", "notes": {"original_bigg_ids": ["ade_c"]}, "charge": 0, "formula": "C5H5N5", "compartment": "c", "id": "ade_c"}, {"name": "Adenine", "notes": {"original_bigg_ids": ["ade_e"]}, "charge": 0, "formula": "C5H5N5", "compartment": "e", "id": "ade_e"}, {"name": "Adenine", "notes": {"original_bigg_ids": ["ade_m"]}, "charge": 0, "formula": "C5H5N5", "compartment": "m", "id": "ade_m"}, {"name": "1 Acyl sn glycerol 3 phosphate C1920H3622O700P100", "notes": {"original_bigg_ids": ["1ag3p_SC_c"]}, "charge": 0, "formula": "C1920H3622O700P100", "compartment": "c", "id": "1ag3p_SC_c"}, {"name": "Nicotinamide adenine dinucleotide phosphate - reduced", "notes": {"original_bigg_ids": ["nadph_c"]}, "charge": 0, "formula": "C21H26N7O17P3", "compartment": "c", "id": "nadph_c"}, {"name": "Nicotinamide adenine dinucleotide phosphate", "notes": {"original_bigg_ids": ["nadp_c"]}, "charge": 0, "formula": "C21H25N7O17P3", "compartment": "c", "id": "nadp_c"}, {"name": "1 Acyl glycerone 3 phosphate yeast specific C1920H3422O700P100", "notes": {"original_bigg_ids": ["1agly3p_SC_c"]}, "charge": 0, "formula": "C1920H3422O700P100", "compartment": "c", "id": "1agly3p_SC_c"}, {"name": "ADP", "notes": {"original_bigg_ids": ["adp_c"]}, "charge": 0, "formula": "C10H12N5O10P2", "compartment": "c", "id": "adp_c"}, {"name": "GDP", "notes": {"original_bigg_ids": ["gdp_c"]}, "charge": 0, "formula": "C10H12N5O11P2", "compartment": "c", "id": "gdp_c"}, {"name": "GTP", "notes": {"original_bigg_ids": ["gtp_c"]}, "charge": 0, "formula": "C10H12N5O14P3", "compartment": "c", "id": "gtp_c"}, {"name": "GTP", "notes": {"original_bigg_ids": ["gtp_m"]}, "charge": 0, "formula": "C10H12N5O14P3", "compartment": "m", "id": "gtp_m"}, {"name": "GDP", "notes": {"original_bigg_ids": ["gdp_m"]}, "charge": 0, "formula": "C10H12N5O11P2", "compartment": "m", "id": "gdp_m"}, {"name": "IDP", "notes": {"original_bigg_ids": ["idp_c"]}, "charge": 0, "formula": "C10H11N4O11P2", "compartment": "c", "id": "idp_c"}, {"name": "ITP", "notes": {"original_bigg_ids": ["itp_c"]}, "charge": 0, "formula": "C10H11N4O14P3", "compartment": "c", "id": "itp_c"}, {"name": "IDP", "notes": {"original_bigg_ids": ["idp_m"]}, "charge": 0, "formula": "C10H11N4O11P2", "compartment": "m", "id": "idp_m"}, {"name": "ITP", "notes": {"original_bigg_ids": ["itp_m"]}, "charge": 0, "formula": "C10H11N4O14P3", "compartment": "m", "id": "itp_m"}, {"name": "CO2", "notes": {"original_bigg_ids": ["co2_c"]}, "charge": 0, "formula": "CO2", "compartment": "c", "id": "co2_c"}, {"name": "S-Adenosylmethioninamine", "notes": {"original_bigg_ids": ["ametam_c"]}, "charge": 0, "formula": "C14H24N6O3S", "compartment": "c", "id": "ametam_c"}, {"name": "S-Adenosyl-L-methionine", "notes": {"original_bigg_ids": ["amet_c"]}, "charge": 0, "formula": "C15H23N6O5S", "compartment": "c", "id": "amet_c"}, {"name": "CAMP", "notes": {"original_bigg_ids": ["camp_c"]}, "charge": 0, "formula": "C10H11N5O6P", "compartment": "c", "id": "camp_c"}, {"name": "D-Ribose", "notes": {"original_bigg_ids": ["rib_DASH_D_c"]}, "charge": 0, "formula": "C5H10O5", "compartment": "c", "id": "rib__D_c"}, {"name": "Adenosine", "notes": {"original_bigg_ids": ["adn_e"]}, "charge": 0, "formula": "C10H13N5O4", "compartment": "e", "id": "adn_e"}, {"name": "5-Phospho-alpha-D-ribose 1-diphosphate", "notes": {"original_bigg_ids": ["prpp_c"]}, "charge": 0, "formula": "C5H8O14P3", "compartment": "c", "id": "prpp_c"}, {"name": "Adenosine 5'-phosphosulfate", "notes": {"original_bigg_ids": ["aps_c"]}, "charge": 0, "formula": "C10H12N5O10PS", "compartment": "c", "id": "aps_c"}, {"name": "3'-Phosphoadenylyl sulfate", "notes": {"original_bigg_ids": ["paps_c"]}, "charge": 0, "formula": "C10H11N5O13P2S", "compartment": "c", "id": "paps_c"}, {"name": "Fumarate", "notes": {"original_bigg_ids": ["fum_c"]}, "charge": 0, "formula": "C4H2O4", "compartment": "c", "id": "fum_c"}, {"name": "N6-(1,2-Dicarboxyethyl)-AMP", "notes": {"original_bigg_ids": ["dcamp_c"]}, "charge": 0, "formula": "C14H14N5O11P", "compartment": "c", "id": "dcamp_c"}, {"name": "(S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate", "notes": {"original_bigg_ids": ["25aics_c"]}, "charge": 0, "formula": "C13H15N4O12P", "compartment": "c", "id": "25aics_c"}, {"name": "5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide", "notes": {"original_bigg_ids": ["aicar_c"]}, "charge": 0, "formula": "C9H13N4O8P", "compartment": "c", "id": "aicar_c"}, {"name": "L-Aspartate", "notes": {"original_bigg_ids": ["asp_DASH_L_c"]}, "charge": 0, "formula": "C4H6NO4", "compartment": "c", "id": "asp__L_c"}, {"name": "IMP", "notes": {"original_bigg_ids": ["imp_c"]}, "charge": 0, "formula": "C10H11N4O8P", "compartment": "c", "id": "imp_c"}, {"name": "Phosphate", "notes": {"original_bigg_ids": ["pi_c"]}, "charge": 0, "formula": "HO4P", "compartment": "c", "id": "pi_c"}, {"name": "1-(5-Phosphoribosyl)-ATP", "notes": {"original_bigg_ids": ["prbatp_c"]}, "charge": 0, "formula": "C15H19N5O20P4", "compartment": "c", "id": "prbatp_c"}, {"name": "Alpha-D-Ribose 5-phosphate", "notes": {"original_bigg_ids": ["r5p_c"]}, "charge": 0, "formula": "C5H9O8P", "compartment": "c", "id": "r5p_c"}, {"name": "N-(5-Phospho-D-ribosyl)anthranilate", "notes": {"original_bigg_ids": ["pran_c"]}, "charge": 0, "formula": "C12H13NO9P", "compartment": "c", "id": "pran_c"}, {"name": "Anthranilate", "notes": {"original_bigg_ids": ["anth_c"]}, "charge": 0, "formula": "C7H6NO2", "compartment": "c", "id": "anth_c"}, {"name": "P1,P4-Bis(5'-adenosyl) tetraphosphate", "notes": {"original_bigg_ids": ["ap4a_c"]}, "charge": 0, "formula": "C20H24N10O19P4", "compartment": "c", "id": "ap4a_c"}, {"name": "5-Amino-6-(5'-phosphoribitylamino)uracil", "notes": {"original_bigg_ids": ["5aprbu_c"]}, "charge": 0, "formula": "C9H15N4O9P", "compartment": "c", "id": "5aprbu_c"}, {"name": "5-Amino-6-(5'-phosphoribosylamino)uracil", "notes": {"original_bigg_ids": ["5apru_c"]}, "charge": 0, "formula": "C9H13N4O9P", "compartment": "c", "id": "5apru_c"}, {"name": "Hydrogen peroxide", "notes": {"original_bigg_ids": ["h2o2_c"]}, "charge": 0, "formula": "H2O2", "compartment": "c", "id": "h2o2_c"}, {"name": "O2", "notes": {"original_bigg_ids": ["o2_c"]}, "charge": 0, "formula": "O2", "compartment": "c", "id": "o2_c"}, {"name": "N4 Acetylaminobutanal C6H11NO2", "notes": {"original_bigg_ids": ["n4abutn_c"]}, "charge": 0, "formula": "C6H11NO2", "compartment": "c", "id": "n4abutn_c"}, {"name": "N Acetylputrescine C6H15N2O", "notes": {"original_bigg_ids": ["aprut_c"]}, "charge": 0, "formula": "C6H15N2O", "compartment": "c", "id": "aprut_c"}, {"name": "Nicotinamide adenine dinucleotide", "notes": {"original_bigg_ids": ["nad_c"]}, "charge": 0, "formula": "C21H26N7O14P2", "compartment": "c", "id": "nad_c"}, {"name": "Nicotinamide adenine dinucleotide - reduced", "notes": {"original_bigg_ids": ["nadh_c"]}, "charge": 0, "formula": "C21H27N7O14P2", "compartment": "c", "id": "nadh_c"}, {"name": "D Arabinono 1 4 lactone C5H8O5", "notes": {"original_bigg_ids": ["Dara14lac_c"]}, "charge": 0, "formula": "C5H8O5", "compartment": "c", "id": "Dara14lac_c"}, {"name": "D Arabinose C5H10O5", "notes": {"original_bigg_ids": ["arab_DASH_D_c"]}, "charge": 0, "formula": "C5H10O5", "compartment": "c", "id": "arab__D_c"}, {"name": "L Arabinitol C5H12O5", "notes": {"original_bigg_ids": ["abt_c"]}, "charge": 0, "formula": "C5H12O5", "compartment": "c", "id": "abt_c"}, {"name": "L-Arabinose", "notes": {"original_bigg_ids": ["arab_DASH_L_c"]}, "charge": 0, "formula": "C5H10O5", "compartment": "c", "id": "arab__L_c"}, {"name": "Urea", "notes": {"original_bigg_ids": ["urea_c"]}, "charge": 0, "formula": "CH4N2O", "compartment": "c", "id": "urea_c"}, {"name": "Ornithine", "notes": {"original_bigg_ids": ["orn_c"]}, "charge": 0, "formula": "C5H13N2O2", "compartment": "c", "id": "orn_c"}, {"name": "L-Arginine", "notes": {"original_bigg_ids": ["arg_DASH_L_c"]}, "charge": 0, "formula": "C6H15N4O2", "compartment": "c", "id": "arg__L_c"}, {"name": "N(omega)-(L-Arginino)succinate", "notes": {"original_bigg_ids": ["argsuc_c"]}, "charge": 0, "formula": "C10H17N4O6", "compartment": "c", "id": "argsuc_c"}, {"name": "L-Citrulline", "notes": {"original_bigg_ids": ["citr_DASH_L_c"]}, "charge": 0, "formula": "C6H13N3O3", "compartment": "c", "id": "citr__L_c"}, {"name": "L-Arginyl-tRNA(Arg)", "notes": {"original_bigg_ids": ["argtrna_c"]}, "charge": 0, "formula": "C6H14N4OR", "compartment": "c", "id": "argtrna_c"}, {"name": "TRNA(Arg)", "notes": {"original_bigg_ids": ["trnaarg_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnaarg_c"}, {"name": "L-Arginyl-tRNA(Arg)", "notes": {"original_bigg_ids": ["argtrna_m"]}, "charge": 0, "formula": "C6H14N4OR", "compartment": "m", "id": "argtrna_m"}, {"name": "L-Arginine", "notes": {"original_bigg_ids": ["arg_DASH_L_m"]}, "charge": 0, "formula": "C6H15N4O2", "compartment": "m", "id": "arg__L_m"}, {"name": "TRNA(Arg)", "notes": {"original_bigg_ids": ["trnaarg_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnaarg_m"}, {"name": "N pai Methyl L histidine C7H11N3O2", "notes": {"original_bigg_ids": ["NPmehis_c"]}, "charge": 0, "formula": "C7H11N3O2", "compartment": "c", "id": "NPmehis_c"}, {"name": "S-Adenosyl-L-homocysteine", "notes": {"original_bigg_ids": ["ahcys_c"]}, "charge": 0, "formula": "C14H20N6O5S", "compartment": "c", "id": "ahcys_c"}, {"name": "L-Histidine", "notes": {"original_bigg_ids": ["his_DASH_L_c"]}, "charge": 0, "formula": "C6H9N3O2", "compartment": "c", "id": "his__L_c"}, {"name": "L-Aspartate 4-semialdehyde", "notes": {"original_bigg_ids": ["aspsa_c"]}, "charge": 0, "formula": "C4H7NO3", "compartment": "c", "id": "aspsa_c"}, {"name": "4-Phospho-L-aspartate", "notes": {"original_bigg_ids": ["4pasp_c"]}, "charge": 0, "formula": "C4H6NO7P", "compartment": "c", "id": "4pasp_c"}, {"name": "L-Asparagine", "notes": {"original_bigg_ids": ["asn_DASH_L_c"]}, "charge": 0, "formula": "C4H8N2O3", "compartment": "c", "id": "asn__L_c"}, {"name": "TRNA(Asn)", "notes": {"original_bigg_ids": ["trnaasn_c"]}, "charge": 0, "formula": "C10H17O10PR2", "compartment": "c", "id": "trnaasn_c"}, {"name": "L-Asparaginyl-tRNA(Asn)", "notes": {"original_bigg_ids": ["asntrna_c"]}, "charge": 0, "formula": "C14H24N2O12PR2", "compartment": "c", "id": "asntrna_c"}, {"name": "TRNA(Asn)", "notes": {"original_bigg_ids": ["trnaasn_m"]}, "charge": 0, "formula": "C10H17O10PR2", "compartment": "m", "id": "trnaasn_m"}, {"name": "L-Asparaginyl-tRNA(Asn)", "notes": {"original_bigg_ids": ["asntrna_m"]}, "charge": 0, "formula": "C14H24N2O12PR2", "compartment": "m", "id": "asntrna_m"}, {"name": "L-Asparagine", "notes": {"original_bigg_ids": ["asn_DASH_L_m"]}, "charge": 0, "formula": "C4H8N2O3", "compartment": "m", "id": "asn__L_m"}, {"name": "Beta-Alanine", "notes": {"original_bigg_ids": ["ala_DASH_B_c"]}, "charge": 0, "formula": "C3H7NO2", "compartment": "c", "id": "ala_B_c"}, {"name": "H+", "notes": {"original_bigg_ids": ["h_n"]}, "charge": 0, "formula": "H", "compartment": "n", "id": "h_n"}, {"name": "Phosphate", "notes": {"original_bigg_ids": ["pi_n"]}, "charge": 0, "formula": "HO4P", "compartment": "n", "id": "pi_n"}, {"name": "Carbamoyl phosphate", "notes": {"original_bigg_ids": ["cbp_n"]}, "charge": 0, "formula": "CH2NO5P", "compartment": "n", "id": "cbp_n"}, {"name": "L-Aspartate", "notes": {"original_bigg_ids": ["asp_DASH_L_n"]}, "charge": 0, "formula": "C4H6NO4", "compartment": "n", "id": "asp__L_n"}, {"name": "N-Carbamoyl-L-aspartate", "notes": {"original_bigg_ids": ["cbasp_n"]}, "charge": 0, "formula": "C5H6N2O5", "compartment": "n", "id": "cbasp_n"}, {"name": "L-Aspartate", "notes": {"original_bigg_ids": ["asp_DASH_L_x"]}, "charge": 0, "formula": "C4H6NO4", "compartment": "x", "id": "asp__L_x"}, {"name": "L-Glutamate", "notes": {"original_bigg_ids": ["glu_DASH_L_x"]}, "charge": 0, "formula": "C5H8NO4", "compartment": "x", "id": "glu__L_x"}, {"name": "Flavin adenine dinucleotide reduced", "notes": {"original_bigg_ids": ["fadh2_m"]}, "charge": 0, "formula": "C27H33N9O15P2", "compartment": "m", "id": "fadh2_m"}, {"name": "Flavin adenine dinucleotide oxidized", "notes": {"original_bigg_ids": ["fad_m"]}, "charge": 0, "formula": "C27H31N9O15P2", "compartment": "m", "id": "fad_m"}, {"name": "Iminoaspartate", "notes": {"original_bigg_ids": ["iasp_c"]}, "charge": 0, "formula": "C4H3NO4", "compartment": "c", "id": "iasp_c"}, {"name": "2-Oxoglutarate", "notes": {"original_bigg_ids": ["akg_c"]}, "charge": 0, "formula": "C5H4O5", "compartment": "c", "id": "akg_c"}, {"name": "Oxaloacetate", "notes": {"original_bigg_ids": ["oaa_c"]}, "charge": 0, "formula": "C4H2O5", "compartment": "c", "id": "oaa_c"}, {"name": "Oxaloacetate", "notes": {"original_bigg_ids": ["oaa_m"]}, "charge": 0, "formula": "C4H2O5", "compartment": "m", "id": "oaa_m"}, {"name": "L-Aspartate", "notes": {"original_bigg_ids": ["asp_DASH_L_m"]}, "charge": 0, "formula": "C4H6NO4", "compartment": "m", "id": "asp__L_m"}, {"name": "2-Oxoglutarate", "notes": {"original_bigg_ids": ["akg_x"]}, "charge": 0, "formula": "C5H4O5", "compartment": "x", "id": "akg_x"}, {"name": "Oxaloacetate", "notes": {"original_bigg_ids": ["oaa_x"]}, "charge": 0, "formula": "C4H2O5", "compartment": "x", "id": "oaa_x"}, {"name": "L-Aspartyl-tRNA(Asp)", "notes": {"original_bigg_ids": ["asptrna_c"]}, "charge": 0, "formula": "C4H5NO3R", "compartment": "c", "id": "asptrna_c"}, {"name": "TRNA(Asp)", "notes": {"original_bigg_ids": ["trnaasp_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnaasp_c"}, {"name": "TRNA(Asp)", "notes": {"original_bigg_ids": ["trnaasp_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnaasp_m"}, {"name": "L-Aspartyl-tRNA(Asp)", "notes": {"original_bigg_ids": ["asptrna_m"]}, "charge": 0, "formula": "C4H5NO3R", "compartment": "m", "id": "asptrna_m"}, {"name": "P1 5 adenosyl P4 5 guanosyl tetraphosphate C20H24N10O20P4", "notes": {"original_bigg_ids": ["ap4g_c"]}, "charge": 0, "formula": "C20H24N10O20P4", "compartment": "c", "id": "ap4g_c"}, {"name": "P1,P4-Bis(5'-guanosyl) tetraphosphate", "notes": {"original_bigg_ids": ["gp4g_c"]}, "charge": 0, "formula": "C20H24N10O21P4", "compartment": "c", "id": "gp4g_c"}, {"name": "1 3 beta D Glucan C6H10O5", "notes": {"original_bigg_ids": ["13BDglcn_c"]}, "charge": 0, "formula": "C6H10O5", "compartment": "c", "id": "13BDglcn_c"}, {"name": "D-Glucose", "notes": {"original_bigg_ids": ["glc_DASH_D_c"]}, "charge": 0, "formula": "C6H12O6", "compartment": "c", "id": "glc__D_c"}, {"name": "1 3 beta D Glucan C6H10O5", "notes": {"original_bigg_ids": ["13BDglcn_e"]}, "charge": 0, "formula": "C6H10O5", "compartment": "e", "id": "13BDglcn_e"}, {"name": "UDPglucose", "notes": {"original_bigg_ids": ["udpg_c"]}, "charge": 0, "formula": "C15H22N2O17P2", "compartment": "c", "id": "udpg_c"}, {"name": "UDP", "notes": {"original_bigg_ids": ["udp_c"]}, "charge": 0, "formula": "C9H11N2O12P2", "compartment": "c", "id": "udp_c"}, {"name": "2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate", "notes": {"original_bigg_ids": ["2dda7p_c"]}, "charge": 0, "formula": "C7H10O10P", "compartment": "c", "id": "2dda7p_c"}, {"name": "2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate", "notes": {"original_bigg_ids": ["2dda7p_m"]}, "charge": 0, "formula": "C7H10O10P", "compartment": "m", "id": "2dda7p_m"}, {"name": "2-Dehydropantoate", "notes": {"original_bigg_ids": ["2dhp_c"]}, "charge": 0, "formula": "C6H9O4", "compartment": "c", "id": "2dhp_c"}, {"name": "2-Dehydropantoate", "notes": {"original_bigg_ids": ["2dhp_m"]}, "charge": 0, "formula": "C6H9O4", "compartment": "m", "id": "2dhp_m"}, {"name": "2-Methylcitrate", "notes": {"original_bigg_ids": ["2mcit_c"]}, "charge": 0, "formula": "C7H7O7", "compartment": "c", "id": "2mcit_c"}, {"name": "2-Methylcitrate", "notes": {"original_bigg_ids": ["2mcit_m"]}, "charge": 0, "formula": "C7H7O7", "compartment": "m", "id": "2mcit_m"}, {"name": "2-Octaprenyl-6-hydroxyphenol (5 repeating units)", "notes": {"original_bigg_ids": ["2ohph_5_n"]}, "charge": 0, "formula": "C36H54O2", "compartment": "n", "id": "2ohph_5_n"}, {"name": "2-Octaprenyl-6-hydroxyphenol (5 repeating units)", "notes": {"original_bigg_ids": ["2ohph_5_c"]}, "charge": 0, "formula": "C36H54O2", "compartment": "c", "id": "2ohph_5_c"}, {"name": "2-Octaprenyl-6-methoxyphenol (5 repeating units)", "notes": {"original_bigg_ids": ["2omph_5_m"]}, "charge": 0, "formula": "C37H56O2", "compartment": "m", "id": "2omph_5_m"}, {"name": "2-Octaprenyl-6-methoxyphenol (5 repeating units)", "notes": {"original_bigg_ids": ["2omph_5_c"]}, "charge": 0, "formula": "C37H56O2", "compartment": "c", "id": "2omph_5_c"}, {"name": "2-Octaprenyl-6-methoxyphenol (5 repeating units)", "notes": {"original_bigg_ids": ["2omph_5_n"]}, "charge": 0, "formula": "C37H56O2", "compartment": "n", "id": "2omph_5_n"}, {"name": "2 Oxoadipate C6H6O5", "notes": {"original_bigg_ids": ["2oxoadp_m"]}, "charge": 0, "formula": "C6H6O5", "compartment": "m", "id": "2oxoadp_m"}, {"name": "2 Oxoadipate C6H6O5", "notes": {"original_bigg_ids": ["2oxoadp_c"]}, "charge": 0, "formula": "C6H6O5", "compartment": "c", "id": "2oxoadp_c"}, {"name": "3-(4-Hydroxyphenyl)pyruvate", "notes": {"original_bigg_ids": ["34hpp_c"]}, "charge": 0, "formula": "C9H7O4", "compartment": "c", "id": "34hpp_c"}, {"name": "Homogentisate C8H7O4", "notes": {"original_bigg_ids": ["hgentis_c"]}, "charge": 0, "formula": "C8H7O4", "compartment": "c", "id": "hgentis_c"}, {"name": "3-(4-Hydroxyphenyl)pyruvate", "notes": {"original_bigg_ids": ["34hpp_m"]}, "charge": 0, "formula": "C9H7O4", "compartment": "m", "id": "34hpp_m"}, {"name": "3-(4-Hydroxyphenyl)pyruvate", "notes": {"original_bigg_ids": ["34hpp_x"]}, "charge": 0, "formula": "C9H7O4", "compartment": "x", "id": "34hpp_x"}, {"name": "3-Carboxy-3-hydroxy-4-methylpentanoate", "notes": {"original_bigg_ids": ["3c3hmp_c"]}, "charge": 0, "formula": "C7H10O5", "compartment": "c", "id": "3c3hmp_c"}, {"name": "3-Carboxy-3-hydroxy-4-methylpentanoate", "notes": {"original_bigg_ids": ["3c3hmp_m"]}, "charge": 0, "formula": "C7H10O5", "compartment": "m", "id": "3c3hmp_m"}, {"name": "3-Carboxy-4-methyl-2-oxopentanoate", "notes": {"original_bigg_ids": ["3c4mop_c"]}, "charge": 0, "formula": "C7H8O5", "compartment": "c", "id": "3c4mop_c"}, {"name": "3-Carboxy-4-methyl-2-oxopentanoate", "notes": {"original_bigg_ids": ["3c4mop_m"]}, "charge": 0, "formula": "C7H8O5", "compartment": "m", "id": "3c4mop_m"}, {"name": "Sphinganine C18H40NO2", "notes": {"original_bigg_ids": ["sphgn_c"]}, "charge": 0, "formula": "C18H40NO2", "compartment": "c", "id": "sphgn_c"}, {"name": "3 Dehydrosphinganine C18H38NO2", "notes": {"original_bigg_ids": ["3dsphgn_c"]}, "charge": 0, "formula": "C18H38NO2", "compartment": "c", "id": "3dsphgn_c"}, {"name": "3 Hydroxyanthranilate C7H7NO3", "notes": {"original_bigg_ids": ["3hanthrn_c"]}, "charge": 0, "formula": "C7H7NO3", "compartment": "c", "id": "3hanthrn_c"}, {"name": "2 Amino 3 carboxymuconate semialdehyde C7H6NO5", "notes": {"original_bigg_ids": ["cmusa_c"]}, "charge": 0, "formula": "C7H6NO5", "compartment": "c", "id": "cmusa_c"}, {"name": "3-Methyl-2-oxobutanoate", "notes": {"original_bigg_ids": ["3mob_m"]}, "charge": 0, "formula": "C5H7O3", "compartment": "m", "id": "3mob_m"}, {"name": "3-Methyl-2-oxobutanoate", "notes": {"original_bigg_ids": ["3mob_c"]}, "charge": 0, "formula": "C5H7O3", "compartment": "c", "id": "3mob_c"}, {"name": "(S)-3-Methyl-2-oxopentanoate", "notes": {"original_bigg_ids": ["3mop_c"]}, "charge": 0, "formula": "C6H9O3", "compartment": "c", "id": "3mop_c"}, {"name": "(S)-3-Methyl-2-oxopentanoate", "notes": {"original_bigg_ids": ["3mop_m"]}, "charge": 0, "formula": "C6H9O3", "compartment": "m", "id": "3mop_m"}, {"name": "3 Hexaprenyl 4 hydroxybenzoate C37H53O3", "notes": {"original_bigg_ids": ["3ophb_5_m"]}, "charge": 0, "formula": "C37H53O3", "compartment": "m", "id": "3ophb_5_m"}, {"name": "3 Hexaprenyl 4 hydroxybenzoate C37H53O3", "notes": {"original_bigg_ids": ["3ophb_5_c"]}, "charge": 0, "formula": "C37H53O3", "compartment": "c", "id": "3ophb_5_c"}, {"name": "4-Aminobutanal", "notes": {"original_bigg_ids": ["4abutn_m"]}, "charge": 0, "formula": "C4H10NO", "compartment": "m", "id": "4abutn_m"}, {"name": "4-Aminobutanal", "notes": {"original_bigg_ids": ["4abutn_c"]}, "charge": 0, "formula": "C4H10NO", "compartment": "c", "id": "4abutn_c"}, {"name": "4-Aminobutanoate", "notes": {"original_bigg_ids": ["4abut_m"]}, "charge": 0, "formula": "C4H9NO2", "compartment": "m", "id": "4abut_m"}, {"name": "4-Aminobutanoate", "notes": {"original_bigg_ids": ["4abut_c"]}, "charge": 0, "formula": "C4H9NO2", "compartment": "c", "id": "4abut_c"}, {"name": "4-Aminobenzoate", "notes": {"original_bigg_ids": ["4abz_m"]}, "charge": 0, "formula": "C7H6NO2", "compartment": "m", "id": "4abz_m"}, {"name": "4 Hydroxy 2 oxoglutarate C5H4O6", "notes": {"original_bigg_ids": ["4h2oglt_m"]}, "charge": 0, "formula": "C5H4O6", "compartment": "m", "id": "4h2oglt_m"}, {"name": "4 Hydroxy 2 oxoglutarate C5H4O6", "notes": {"original_bigg_ids": ["4h2oglt_c"]}, "charge": 0, "formula": "C5H4O6", "compartment": "c", "id": "4h2oglt_c"}, {"name": "4 Hydroxy 2 oxoglutarate C5H4O6", "notes": {"original_bigg_ids": ["4h2oglt_x"]}, "charge": 0, "formula": "C5H4O6", "compartment": "x", "id": "4h2oglt_x"}, {"name": "4-Hydroxybenzoate", "notes": {"original_bigg_ids": ["4hbz_c"]}, "charge": 0, "formula": "C7H5O3", "compartment": "c", "id": "4hbz_c"}, {"name": "4-Hydroxybenzoate", "notes": {"original_bigg_ids": ["4hbz_m"]}, "charge": 0, "formula": "C7H5O3", "compartment": "m", "id": "4hbz_m"}, {"name": "L 4 Hydroxyglutamate semialdehyde C5H9NO4", "notes": {"original_bigg_ids": ["4hglusa_m"]}, "charge": 0, "formula": "C5H9NO4", "compartment": "m", "id": "4hglusa_m"}, {"name": "L erythro 4 Hydroxyglutamate C5H8NO5", "notes": {"original_bigg_ids": ["e4hglu_m"]}, "charge": 0, "formula": "C5H8NO5", "compartment": "m", "id": "e4hglu_m"}, {"name": "Nicotinamide adenine dinucleotide - reduced", "notes": {"original_bigg_ids": ["nadh_m"]}, "charge": 0, "formula": "C21H27N7O14P2", "compartment": "m", "id": "nadh_m"}, {"name": "Nicotinamide adenine dinucleotide", "notes": {"original_bigg_ids": ["nad_m"]}, "charge": 0, "formula": "C21H26N7O14P2", "compartment": "m", "id": "nad_m"}, {"name": "Trans 4 Hydroxy L proline C5H9NO3", "notes": {"original_bigg_ids": ["4hpro_DASH_LT_m"]}, "charge": 0, "formula": "C5H9NO3", "compartment": "m", "id": "4hpro_LT_m"}, {"name": "Trans 4 Hydroxy L proline C5H9NO3", "notes": {"original_bigg_ids": ["4hpro_DASH_LT_c"]}, "charge": 0, "formula": "C5H9NO3", "compartment": "c", "id": "4hpro_LT_c"}, {"name": "O-Phospho-4-hydroxy-L-threonine", "notes": {"original_bigg_ids": ["phthr_c"]}, "charge": 0, "formula": "C4H8NO7P", "compartment": "c", "id": "phthr_c"}, {"name": "4-Hydroxy-L-threonine", "notes": {"original_bigg_ids": ["4hthr_c"]}, "charge": 0, "formula": "C4H9NO4", "compartment": "c", "id": "4hthr_c"}, {"name": "5-Amino-4-oxopentanoate", "notes": {"original_bigg_ids": ["5aop_e"]}, "charge": 0, "formula": "C5H9NO3", "compartment": "e", "id": "5aop_e"}, {"name": "5-Amino-4-oxopentanoate", "notes": {"original_bigg_ids": ["5aop_c"]}, "charge": 0, "formula": "C5H9NO3", "compartment": "c", "id": "5aop_c"}, {"name": "5-Amino-4-oxopentanoate", "notes": {"original_bigg_ids": ["5aop_m"]}, "charge": 0, "formula": "C5H9NO3", "compartment": "m", "id": "5aop_m"}, {"name": "5-Methyltetrahydrofolate", "notes": {"original_bigg_ids": ["5mthf_c"]}, "charge": 0, "formula": "C20H24N7O6", "compartment": "c", "id": "5mthf_c"}, {"name": "5-Methyltetrahydrofolate", "notes": {"original_bigg_ids": ["5mthf_m"]}, "charge": 0, "formula": "C20H24N7O6", "compartment": "m", "id": "5mthf_m"}, {"name": "6-phospho-D-glucono-1,5-lactone", "notes": {"original_bigg_ids": ["6pgl_r"]}, "charge": 0, "formula": "C6H9O9P", "compartment": "r", "id": "6pgl_r"}, {"name": "6-phospho-D-glucono-1,5-lactone", "notes": {"original_bigg_ids": ["6pgl_c"]}, "charge": 0, "formula": "C6H9O9P", "compartment": "c", "id": "6pgl_c"}, {"name": "8-Amino-7-oxononanoate", "notes": {"original_bigg_ids": ["8aonn_c"]}, "charge": 0, "formula": "C9H17NO3", "compartment": "c", "id": "8aonn_c"}, {"name": "8-Amino-7-oxononanoate", "notes": {"original_bigg_ids": ["8aonn_e"]}, "charge": 0, "formula": "C9H17NO3", "compartment": "e", "id": "8aonn_e"}, {"name": "4 Acetamidobutanoate C6H10NO3", "notes": {"original_bigg_ids": ["4aabutn_c"]}, "charge": 0, "formula": "C6H10NO3", "compartment": "c", "id": "4aabutn_c"}, {"name": "L 2 Aminoadipate 6 semialdehyde C6H11NO3", "notes": {"original_bigg_ids": ["L2aadp6sa_c"]}, "charge": 0, "formula": "C6H11NO3", "compartment": "c", "id": "L2aadp6sa_c"}, {"name": "L 2 Aminoadipate C6H10NO4", "notes": {"original_bigg_ids": ["L2aadp_c"]}, "charge": 0, "formula": "C6H10NO4", "compartment": "c", "id": "L2aadp_c"}, {"name": "Succinic semialdehyde", "notes": {"original_bigg_ids": ["sucsal_c"]}, "charge": 0, "formula": "C4H5O3", "compartment": "c", "id": "sucsal_c"}, {"name": "L Arabinitol C5H12O5", "notes": {"original_bigg_ids": ["abt_e"]}, "charge": 0, "formula": "C5H12O5", "compartment": "e", "id": "abt_e"}, {"name": "4-Aminobutanoate", "notes": {"original_bigg_ids": ["4abut_e"]}, "charge": 0, "formula": "C4H9NO2", "compartment": "e", "id": "4abut_e"}, {"name": "Acetoacetyl-CoA", "notes": {"original_bigg_ids": ["aacoa_c"]}, "charge": 0, "formula": "C25H36N7O18P3S", "compartment": "c", "id": "aacoa_c"}, {"name": "Acetoacetyl-CoA", "notes": {"original_bigg_ids": ["aacoa_m"]}, "charge": 0, "formula": "C25H36N7O18P3S", "compartment": "m", "id": "aacoa_m"}, {"name": "Octanoyl-CoA (n-C8:0CoA)", "notes": {"original_bigg_ids": ["occoa_x"]}, "charge": 0, "formula": "C29H46N7O17P3S", "compartment": "x", "id": "occoa_x"}, {"name": "3-Oxodecanoyl-CoA", "notes": {"original_bigg_ids": ["3odcoa_x"]}, "charge": 0, "formula": "C31H48N7O18P3S", "compartment": "x", "id": "3odcoa_x"}, {"name": "3-Oxododecanoyl-CoA", "notes": {"original_bigg_ids": ["3oddcoa_x"]}, "charge": 0, "formula": "C33H52N7O18P3S", "compartment": "x", "id": "3oddcoa_x"}, {"name": "3-Oxotetradecanoyl-CoA", "notes": {"original_bigg_ids": ["3otdcoa_x"]}, "charge": 0, "formula": "C35H56N7O18P3S", "compartment": "x", "id": "3otdcoa_x"}, {"name": "3-Oxohexadecanoyl-CoA", "notes": {"original_bigg_ids": ["3ohdcoa_x"]}, "charge": 0, "formula": "C37H60N7O18P3S", "compartment": "x", "id": "3ohdcoa_x"}, {"name": "3 Oxooctadecanoyl CoA C39H64N7O18P3S", "notes": {"original_bigg_ids": ["3ohodcoa_x"]}, "charge": 0, "formula": "C39H64N7O18P3S", "compartment": "x", "id": "3ohodcoa_x"}, {"name": "3 Oxohexacosyl CoA C47H80N7O18P3S", "notes": {"original_bigg_ids": ["3ohxccoa_x"]}, "charge": 0, "formula": "C47H80N7O18P3S", "compartment": "x", "id": "3ohxccoa_x"}, {"name": "Tetracosanoyl CoA n C240CoA C45H78N7O17P3S", "notes": {"original_bigg_ids": ["ttccoa_x"]}, "charge": 0, "formula": "C45H78N7O17P3S", "compartment": "x", "id": "ttccoa_x"}, {"name": "Acetaldehyde", "notes": {"original_bigg_ids": ["acald_c"]}, "charge": 0, "formula": "C2H4O", "compartment": "c", "id": "acald_c"}, {"name": "Acetaldehyde", "notes": {"original_bigg_ids": ["acald_e"]}, "charge": 0, "formula": "C2H4O", "compartment": "e", "id": "acald_e"}, {"name": "Malonyl-CoA", "notes": {"original_bigg_ids": ["malcoa_c"]}, "charge": 0, "formula": "C24H33N7O19P3S", "compartment": "c", "id": "malcoa_c"}, {"name": "Bicarbonate", "notes": {"original_bigg_ids": ["hco3_c"]}, "charge": 0, "formula": "CHO3", "compartment": "c", "id": "hco3_c"}, {"name": "D-Glucosamine 6-phosphate", "notes": {"original_bigg_ids": ["gam6p_c"]}, "charge": 0, "formula": "C6H13NO8P", "compartment": "c", "id": "gam6p_c"}, {"name": "Decanoyl-CoA (n-C10:0CoA)", "notes": {"original_bigg_ids": ["dcacoa_c"]}, "charge": 0, "formula": "C31H50N7O17P3S", "compartment": "c", "id": "dcacoa_c"}, {"name": "Dodecanoyl-CoA (n-C12:0CoA)", "notes": {"original_bigg_ids": ["ddcacoa_c"]}, "charge": 0, "formula": "C33H54N7O17P3S", "compartment": "c", "id": "ddcacoa_c"}, {"name": "Phosphatidate yeast specific C3540H6544O800P100", "notes": {"original_bigg_ids": ["pa_SC_c"]}, "charge": 0, "formula": "C3540H6544O800P100", "compartment": "c", "id": "pa_SC_c"}, {"name": "Octadecynoyl CoA n C182CoA C39H62N7O17P3S", "notes": {"original_bigg_ids": ["ocdycacoa_c"]}, "charge": 0, "formula": "C39H62N7O17P3S", "compartment": "c", "id": "ocdycacoa_c"}, {"name": "Phosphate", "notes": {"original_bigg_ids": ["pi_m"]}, "charge": 0, "formula": "HO4P", "compartment": "m", "id": "pi_m"}, {"name": "Nicotinamide adenine dinucleotide phosphate - reduced", "notes": {"original_bigg_ids": ["nadph_m"]}, "charge": 0, "formula": "C21H26N7O17P3", "compartment": "m", "id": "nadph_m"}, {"name": "Nicotinamide adenine dinucleotide phosphate", "notes": {"original_bigg_ids": ["nadp_m"]}, "charge": 0, "formula": "C21H25N7O17P3", "compartment": "m", "id": "nadp_m"}, {"name": "Glycine", "notes": {"original_bigg_ids": ["gly_c"]}, "charge": 0, "formula": "C2H5NO2", "compartment": "c", "id": "gly_c"}, {"name": "Glyoxylate", "notes": {"original_bigg_ids": ["glx_c"]}, "charge": 0, "formula": "C2H1O3", "compartment": "c", "id": "glx_c"}, {"name": "L-Alanine", "notes": {"original_bigg_ids": ["ala_DASH_L_c"]}, "charge": 0, "formula": "C3H7NO2", "compartment": "c", "id": "ala__L_c"}, {"name": "S-Adenosyl-L-homocysteine", "notes": {"original_bigg_ids": ["ahcys_m"]}, "charge": 0, "formula": "C14H20N6O5S", "compartment": "m", "id": "ahcys_m"}, {"name": "S-Adenosyl-L-homocysteine", "notes": {"original_bigg_ids": ["ahcys_n"]}, "charge": 0, "formula": "C14H20N6O5S", "compartment": "n", "id": "ahcys_n"}, {"name": "L-Homocysteine", "notes": {"original_bigg_ids": ["hcys_DASH_L_c"]}, "charge": 0, "formula": "C4H9NO2S", "compartment": "c", "id": "hcys__L_c"}, {"name": "4-Amino-5-hydroxymethyl-2-methylpyrimidine", "notes": {"original_bigg_ids": ["4ahmmp_c"]}, "charge": 0, "formula": "C6H9N3O", "compartment": "c", "id": "4ahmmp_c"}, {"name": "Glycolaldehyde", "notes": {"original_bigg_ids": ["gcald_c"]}, "charge": 0, "formula": "C2H4O2", "compartment": "c", "id": "gcald_c"}, {"name": "5-amino-1-(5-phospho-D-ribosyl)imidazole", "notes": {"original_bigg_ids": ["air_c"]}, "charge": 0, "formula": "C8H12N3O7P", "compartment": "c", "id": "air_c"}, {"name": "Methanethiol CH4S", "notes": {"original_bigg_ids": ["ch4s_c"]}, "charge": 0, "formula": "CH4S", "compartment": "c", "id": "ch4s_c"}, {"name": "O Acetyl L homoserine C6H11NO4", "notes": {"original_bigg_ids": ["achms_c"]}, "charge": 0, "formula": "C6H11NO4", "compartment": "c", "id": "achms_c"}, {"name": "L-Methionine", "notes": {"original_bigg_ids": ["met_DASH_L_c"]}, "charge": 0, "formula": "C5H11NO2S", "compartment": "c", "id": "met__L_c"}, {"name": "Hydrogen sulfide", "notes": {"original_bigg_ids": ["h2s_c"]}, "charge": 0, "formula": "H2S", "compartment": "c", "id": "h2s_c"}, {"name": "5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide", "notes": {"original_bigg_ids": ["fprica_c"]}, "charge": 0, "formula": "C10H13N4O9P", "compartment": "c", "id": "fprica_c"}, {"name": "10-Formyltetrahydrofolate", "notes": {"original_bigg_ids": ["10fthf_c"]}, "charge": 0, "formula": "C20H21N7O7", "compartment": "c", "id": "10fthf_c"}, {"name": "5,6,7,8-Tetrahydrofolate", "notes": {"original_bigg_ids": ["thf_c"]}, "charge": 0, "formula": "C19H21N7O6", "compartment": "c", "id": "thf_c"}, {"name": "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate", "notes": {"original_bigg_ids": ["5aizc_c"]}, "charge": 0, "formula": "C9H11N3O9P", "compartment": "c", "id": "5aizc_c"}, {"name": "S Succinyldihydrolipoamide C12H20NO4S2", "notes": {"original_bigg_ids": ["sdhlam_m"]}, "charge": 0, "formula": "C12H20NO4S2", "compartment": "m", "id": "sdhlam_m"}, {"name": "Lipoamide C8H15NOS2", "notes": {"original_bigg_ids": ["lpam_m"]}, "charge": 0, "formula": "C8H15NOS2", "compartment": "m", "id": "lpam_m"}, {"name": "Dihydrolipoamide C8H17NOS2", "notes": {"original_bigg_ids": ["dhlam_m"]}, "charge": 0, "formula": "C8H17NOS2", "compartment": "m", "id": "dhlam_m"}, {"name": "Succinyl-CoA", "notes": {"original_bigg_ids": ["succoa_m"]}, "charge": 0, "formula": "C25H35N7O19P3S", "compartment": "m", "id": "succoa_m"}, {"name": "L-Malate", "notes": {"original_bigg_ids": ["mal_DASH_L_c"]}, "charge": 0, "formula": "C4H4O5", "compartment": "c", "id": "mal__L_c"}, {"name": "2-Oxoglutarate", "notes": {"original_bigg_ids": ["akg_e"]}, "charge": 0, "formula": "C5H4O5", "compartment": "e", "id": "akg_e"}, {"name": "2-Oxoglutarate", "notes": {"original_bigg_ids": ["akg_n"]}, "charge": 0, "formula": "C5H4O5", "compartment": "n", "id": "akg_n"}, {"name": "Dihydroneopterin", "notes": {"original_bigg_ids": ["dhnpt_c"]}, "charge": 0, "formula": "C9H13N5O4", "compartment": "c", "id": "dhnpt_c"}, {"name": "2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate", "notes": {"original_bigg_ids": ["ahdt_c"]}, "charge": 0, "formula": "C9H12N5O13P3", "compartment": "c", "id": "ahdt_c"}, {"name": "Glycine", "notes": {"original_bigg_ids": ["gly_m"]}, "charge": 0, "formula": "C2H5NO2", "compartment": "m", "id": "gly_m"}, {"name": "L-Alanine", "notes": {"original_bigg_ids": ["ala_DASH_L_m"]}, "charge": 0, "formula": "C3H7NO2", "compartment": "m", "id": "ala__L_m"}, {"name": "TRNA(Ala)", "notes": {"original_bigg_ids": ["trnaala_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnaala_c"}, {"name": "L-Alanyl-tRNA(Ala)", "notes": {"original_bigg_ids": ["alatrna_c"]}, "charge": 0, "formula": "C3H6NOR", "compartment": "c", "id": "alatrna_c"}, {"name": "D-Glyceraldehyde", "notes": {"original_bigg_ids": ["glyald_c"]}, "charge": 0, "formula": "C3H6O3", "compartment": "c", "id": "glyald_c"}, {"name": "Glycerol", "notes": {"original_bigg_ids": ["glyc_c"]}, "charge": 0, "formula": "C3H8O3", "compartment": "c", "id": "glyc_c"}, {"name": "Ethanol", "notes": {"original_bigg_ids": ["etoh_m"]}, "charge": 0, "formula": "C2H6O", "compartment": "m", "id": "etoh_m"}, {"name": "Acetaldehyde", "notes": {"original_bigg_ids": ["acald_m"]}, "charge": 0, "formula": "C2H4O", "compartment": "m", "id": "acald_m"}, {"name": "Ethanol", "notes": {"original_bigg_ids": ["etoh_c"]}, "charge": 0, "formula": "C2H6O", "compartment": "c", "id": "etoh_c"}, {"name": "Phenylacetic acid", "notes": {"original_bigg_ids": ["pac_c"]}, "charge": 0, "formula": "C8H7O2", "compartment": "c", "id": "pac_c"}, {"name": "Phenylacetaldehyde", "notes": {"original_bigg_ids": ["pacald_c"]}, "charge": 0, "formula": "C8H8O", "compartment": "c", "id": "pacald_c"}, {"name": "Indole 3 acetaldehyde C10H9NO", "notes": {"original_bigg_ids": ["id3acald_m"]}, "charge": 0, "formula": "C10H9NO", "compartment": "m", "id": "id3acald_m"}, {"name": "Indole 3 acetate C10H8NO2", "notes": {"original_bigg_ids": ["ind3ac_m"]}, "charge": 0, "formula": "C10H8NO2", "compartment": "m", "id": "ind3ac_m"}, {"name": "Indole 3 acetaldehyde C10H9NO", "notes": {"original_bigg_ids": ["id3acald_c"]}, "charge": 0, "formula": "C10H9NO", "compartment": "c", "id": "id3acald_c"}, {"name": "Indole 3 acetate C10H8NO2", "notes": {"original_bigg_ids": ["ind3ac_c"]}, "charge": 0, "formula": "C10H8NO2", "compartment": "c", "id": "ind3ac_c"}, {"name": "Allantoate", "notes": {"original_bigg_ids": ["alltt_c"]}, "charge": 0, "formula": "C4H7N4O4", "compartment": "c", "id": "alltt_c"}, {"name": "(-)-Ureidoglycolate", "notes": {"original_bigg_ids": ["urdglyc_c"]}, "charge": 0, "formula": "C3H5N2O4", "compartment": "c", "id": "urdglyc_c"}, {"name": "Allantoin", "notes": {"original_bigg_ids": ["alltn_c"]}, "charge": 0, "formula": "C4H6N4O3", "compartment": "c", "id": "alltn_c"}, {"name": "Allophanate C2H3N2O3", "notes": {"original_bigg_ids": ["allphn_c"]}, "charge": 0, "formula": "C2H3N2O3", "compartment": "c", "id": "allphn_c"}, {"name": "2-Aminomuconate", "notes": {"original_bigg_ids": ["amuco_c"]}, "charge": 0, "formula": "C6H6NO4", "compartment": "c", "id": "amuco_c"}, {"name": "2-Aminomuconate 6-semialdehyde", "notes": {"original_bigg_ids": ["am6sa_c"]}, "charge": 0, "formula": "C6H7NO3", "compartment": "c", "id": "am6sa_c"}, {"name": "S-Adenosyl-4-methylthio-2-oxobutanoate", "notes": {"original_bigg_ids": ["amob_c"]}, "charge": 0, "formula": "C15H19N5O6S", "compartment": "c", "id": "amob_c"}, {"name": "7,8-Diaminononanoate", "notes": {"original_bigg_ids": ["dann_c"]}, "charge": 0, "formula": "C9H21N2O2", "compartment": "c", "id": "dann_c"}, {"name": "S-Adenosyl-L-methionine", "notes": {"original_bigg_ids": ["amet_m"]}, "charge": 0, "formula": "C15H23N6O5S", "compartment": "m", "id": "amet_m"}, {"name": "S-Adenosyl-L-methionine", "notes": {"original_bigg_ids": ["amet_n"]}, "charge": 0, "formula": "C15H23N6O5S", "compartment": "n", "id": "amet_n"}, {"name": "4 Guanidinobutanoate C5H11N3O2", "notes": {"original_bigg_ids": ["4gudbutn_c"]}, "charge": 0, "formula": "C5H11N3O2", "compartment": "c", "id": "4gudbutn_c"}, {"name": "4 Guanidinobutanamide C5H13N4O", "notes": {"original_bigg_ids": ["4gudbd_c"]}, "charge": 0, "formula": "C5H13N4O", "compartment": "c", "id": "4gudbd_c"}, {"name": "2 Phenylacetamide C8H9NO", "notes": {"original_bigg_ids": ["pad_c"]}, "charge": 0, "formula": "C8H9NO", "compartment": "c", "id": "pad_c"}, {"name": "Indole 3 acetamide C10H10N2O", "notes": {"original_bigg_ids": ["iad_c"]}, "charge": 0, "formula": "C10H10N2O", "compartment": "c", "id": "iad_c"}, {"name": "Phosphate", "notes": {"original_bigg_ids": ["pi_g"]}, "charge": 0, "formula": "HO4P", "compartment": "g", "id": "pi_g"}, {"name": "H+", "notes": {"original_bigg_ids": ["h_g"]}, "charge": 0, "formula": "H", "compartment": "g", "id": "h_g"}, {"name": "ADP", "notes": {"original_bigg_ids": ["adp_g"]}, "charge": 0, "formula": "C10H12N5O10P2", "compartment": "g", "id": "adp_g"}, {"name": "H2O", "notes": {"original_bigg_ids": ["h2o_g"]}, "charge": 0, "formula": "H2O", "compartment": "g", "id": "h2o_g"}, {"name": "ATP", "notes": {"original_bigg_ids": ["atp_g"]}, "charge": 0, "formula": "C10H12N5O13P3", "compartment": "g", "id": "atp_g"}, {"name": "ADP", "notes": {"original_bigg_ids": ["adp_v"]}, "charge": 0, "formula": "C10H12N5O10P2", "compartment": "v", "id": "adp_v"}, {"name": "H2O", "notes": {"original_bigg_ids": ["h2o_v"]}, "charge": 0, "formula": "H2O", "compartment": "v", "id": "h2o_v"}, {"name": "ATP", "notes": {"original_bigg_ids": ["atp_v"]}, "charge": 0, "formula": "C10H12N5O13P3", "compartment": "v", "id": "atp_v"}, {"name": "Phosphate", "notes": {"original_bigg_ids": ["pi_v"]}, "charge": 0, "formula": "HO4P", "compartment": "v", "id": "pi_v"}, {"name": "H+", "notes": {"original_bigg_ids": ["h_v"]}, "charge": 0, "formula": "H", "compartment": "v", "id": "h_v"}, {"name": "Adenosine 3',5'-bisphosphate", "notes": {"original_bigg_ids": ["pap_c"]}, "charge": 0, "formula": "C10H11N5O10P2", "compartment": "c", "id": "pap_c"}, {"name": "Biotin", "notes": {"original_bigg_ids": ["btn_c"]}, "charge": 0, "formula": "C10H15N2O3S", "compartment": "c", "id": "btn_c"}, {"name": "Sulfur", "notes": {"original_bigg_ids": ["s_c"]}, "charge": 0, "formula": "S", "compartment": "c", "id": "s_c"}, {"name": "Dethiobiotin", "notes": {"original_bigg_ids": ["dtbt_c"]}, "charge": 0, "formula": "C10H17N2O3", "compartment": "c", "id": "dtbt_c"}, {"name": "4 4 dimethylzymosterol C29H48O", "notes": {"original_bigg_ids": ["44mzym_c"]}, "charge": 0, "formula": "C29H48O", "compartment": "c", "id": "44mzym_c"}, {"name": "4 4 dimethylcholesta 8 14 24 trienol C29H46O", "notes": {"original_bigg_ids": ["44mctr_c"]}, "charge": 0, "formula": "C29H46O", "compartment": "c", "id": "44mctr_c"}, {"name": "Ergosta 5 7 24 28 trienol C28H44O", "notes": {"original_bigg_ids": ["ergtrol_c"]}, "charge": 0, "formula": "C28H44O", "compartment": "c", "id": "ergtrol_c"}, {"name": "Ergosta 5 7 22 24 28 tetraen 3beta ol C28H42O", "notes": {"original_bigg_ids": ["ergtetrol_c"]}, "charge": 0, "formula": "C28H42O", "compartment": "c", "id": "ergtetrol_c"}, {"name": "Nicotinamide adenine dinucleotide phosphate", "notes": {"original_bigg_ids": ["nadp_r"]}, "charge": 0, "formula": "C21H25N7O17P3", "compartment": "r", "id": "nadp_r"}, {"name": "H+", "notes": {"original_bigg_ids": ["h_r"]}, "charge": 0, "formula": "H", "compartment": "r", "id": "h_r"}, {"name": "Nicotinamide adenine dinucleotide phosphate - reduced", "notes": {"original_bigg_ids": ["nadph_r"]}, "charge": 0, "formula": "C21H26N7O17P3", "compartment": "r", "id": "nadph_r"}, {"name": "Ergosta 5 7 22 24 28 tetraen 3beta ol C28H42O", "notes": {"original_bigg_ids": ["ergtetrol_r"]}, "charge": 0, "formula": "C28H42O", "compartment": "r", "id": "ergtetrol_r"}, {"name": "Ergosterol C28H44O", "notes": {"original_bigg_ids": ["ergst_r"]}, "charge": 0, "formula": "C28H44O", "compartment": "r", "id": "ergst_r"}, {"name": "4 Methylzymosterol intermediate 1 C29H46O3", "notes": {"original_bigg_ids": ["4mzym_int1_c"]}, "charge": 0, "formula": "C29H46O3", "compartment": "c", "id": "4mzym_int1_c"}, {"name": "4 Methylzymosterol intermediate 2 C28H44O", "notes": {"original_bigg_ids": ["4mzym_int2_c"]}, "charge": 0, "formula": "C28H44O", "compartment": "c", "id": "4mzym_int2_c"}, {"name": "Zymosterol intermediate 2 C27H42O", "notes": {"original_bigg_ids": ["zym_int2_c"]}, "charge": 0, "formula": "C27H42O", "compartment": "c", "id": "zym_int2_c"}, {"name": "Zymosterol intermediate 1 C28H44O3", "notes": {"original_bigg_ids": ["zym_int1_c"]}, "charge": 0, "formula": "C28H44O3", "compartment": "c", "id": "zym_int1_c"}, {"name": "4 methylzymosterol C28H46O", "notes": {"original_bigg_ids": ["4mzym_c"]}, "charge": 0, "formula": "C28H46O", "compartment": "c", "id": "4mzym_c"}, {"name": "Zymosterol C27H44O", "notes": {"original_bigg_ids": ["zymst_c"]}, "charge": 0, "formula": "C27H44O", "compartment": "c", "id": "zymst_c"}, {"name": "Episterol C28H46O", "notes": {"original_bigg_ids": ["epist_c"]}, "charge": 0, "formula": "C28H46O", "compartment": "c", "id": "epist_c"}, {"name": "Fecosterol C28H46O", "notes": {"original_bigg_ids": ["fecost_c"]}, "charge": 0, "formula": "C28H46O", "compartment": "c", "id": "fecost_c"}, {"name": "N-Carbamoyl-L-aspartate", "notes": {"original_bigg_ids": ["cbasp_c"]}, "charge": 0, "formula": "C5H6N2O5", "compartment": "c", "id": "cbasp_c"}, {"name": "Carbamoyl phosphate", "notes": {"original_bigg_ids": ["cbp_c"]}, "charge": 0, "formula": "CH2NO5P", "compartment": "c", "id": "cbp_c"}, {"name": "L-Glutamine", "notes": {"original_bigg_ids": ["gln_DASH_L_n"]}, "charge": 0, "formula": "C5H10N2O3", "compartment": "n", "id": "gln__L_n"}, {"name": "ADP", "notes": {"original_bigg_ids": ["adp_n"]}, "charge": 0, "formula": "C10H12N5O10P2", "compartment": "n", "id": "adp_n"}, {"name": "ATP", "notes": {"original_bigg_ids": ["atp_n"]}, "charge": 0, "formula": "C10H12N5O13P3", "compartment": "n", "id": "atp_n"}, {"name": "H2O", "notes": {"original_bigg_ids": ["h2o_n"]}, "charge": 0, "formula": "H2O", "compartment": "n", "id": "h2o_n"}, {"name": "Bicarbonate", "notes": {"original_bigg_ids": ["hco3_n"]}, "charge": 0, "formula": "CHO3", "compartment": "n", "id": "hco3_n"}, {"name": "L-Glutamate", "notes": {"original_bigg_ids": ["glu_DASH_L_n"]}, "charge": 0, "formula": "C5H8NO4", "compartment": "n", "id": "glu__L_n"}, {"name": "CDPdiacylglycerol yeast specific C4440H7744N300O1500P200", "notes": {"original_bigg_ids": ["cdpdag_SC_m"]}, "charge": 0, "formula": "C4440H7744N300O1500P200", "compartment": "m", "id": "cdpdag_SC_m"}, {"name": "Phosphatidylglycerophosphate yeast specific C3840H7144O1300P200", "notes": {"original_bigg_ids": ["pgp_SC_m"]}, "charge": 0, "formula": "C3840H7144O1300P200", "compartment": "m", "id": "pgp_SC_m"}, {"name": "CMP", "notes": {"original_bigg_ids": ["cmp_m"]}, "charge": 0, "formula": "C9H12N3O8P", "compartment": "m", "id": "cmp_m"}, {"name": "Glycerol 3-phosphate", "notes": {"original_bigg_ids": ["glyc3p_m"]}, "charge": 0, "formula": "C3H7O6P", "compartment": "m", "id": "glyc3p_m"}, {"name": "CDP", "notes": {"original_bigg_ids": ["cdp_c"]}, "charge": 0, "formula": "C9H12N3O11P2", "compartment": "c", "id": "cdp_c"}, {"name": "CDP", "notes": {"original_bigg_ids": ["cdp_n"]}, "charge": 0, "formula": "C9H12N3O11P2", "compartment": "n", "id": "cdp_n"}, {"name": "Ceramide 1 Sphinganinen C240 C42H85NO3", "notes": {"original_bigg_ids": ["cer1_24_c"]}, "charge": 0, "formula": "C42H85NO3", "compartment": "c", "id": "cer1_24_c"}, {"name": "Ceramide 2 Phytosphingosinen C240 C42H85NO4", "notes": {"original_bigg_ids": ["cer2_24_c", "cer2_APOS__24_c"]}, "charge": 0, "formula": "C42H85NO4", "compartment": "c", "id": "cer2_24_c"}, {"name": "Ceramide 1 Sphinganinen C260 C44H89NO3", "notes": {"original_bigg_ids": ["cer1_26_c"]}, "charge": 0, "formula": "C44H89NO3", "compartment": "c", "id": "cer1_26_c"}, {"name": "Ceramide 2 Phytosphingosinen C260 C44H89NO4", "notes": {"original_bigg_ids": ["cer2_26_c", "cer2_APOS__26_c"]}, "charge": 0, "formula": "C44H89NO4", "compartment": "c", "id": "cer2_26_c"}, {"name": "Tetracosanoyl CoA n C240CoA C45H78N7O17P3S", "notes": {"original_bigg_ids": ["ttccoa_c"]}, "charge": 0, "formula": "C45H78N7O17P3S", "compartment": "c", "id": "ttccoa_c"}, {"name": "Hexacosanoyl CoA n C260CoA C47H82N7O17P3S", "notes": {"original_bigg_ids": ["hexccoa_c"]}, "charge": 0, "formula": "C47H82N7O17P3S", "compartment": "c", "id": "hexccoa_c"}, {"name": "Phytosphingosine C18H40NO3", "notes": {"original_bigg_ids": ["psphings_c"]}, "charge": 0, "formula": "C18H40NO3", "compartment": "c", "id": "psphings_c"}, {"name": "Ceramide 3 Phytosphingosinen C240OH C42H85NO5", "notes": {"original_bigg_ids": ["cer3_24_c"]}, "charge": 0, "formula": "C42H85NO5", "compartment": "c", "id": "cer3_24_c"}, {"name": "Ceramide 3 Phytosphingosinen C260OH C44H89NO5", "notes": {"original_bigg_ids": ["cer3_26_c"]}, "charge": 0, "formula": "C44H89NO5", "compartment": "c", "id": "cer3_26_c"}, {"name": "Choline phosphate C5H13NO4P", "notes": {"original_bigg_ids": ["cholp_c"]}, "charge": 0, "formula": "C5H13NO4P", "compartment": "c", "id": "cholp_c"}, {"name": "CTP", "notes": {"original_bigg_ids": ["ctp_c"]}, "charge": 0, "formula": "C9H12N3O14P3", "compartment": "c", "id": "ctp_c"}, {"name": "CDPcholine C14H25N4O11P2", "notes": {"original_bigg_ids": ["cdpchol_c"]}, "charge": 0, "formula": "C14H25N4O11P2", "compartment": "c", "id": "cdpchol_c"}, {"name": "Choline", "notes": {"original_bigg_ids": ["chol_c"]}, "charge": 0, "formula": "C5H14NO", "compartment": "c", "id": "chol_c"}, {"name": "Prephenate", "notes": {"original_bigg_ids": ["pphn_c"]}, "charge": 0, "formula": "C10H8O6", "compartment": "c", "id": "pphn_c"}, {"name": "5-O-(1-Carboxyvinyl)-3-phosphoshikimate", "notes": {"original_bigg_ids": ["3psme_c"]}, "charge": 0, "formula": "C10H9O10P", "compartment": "c", "id": "3psme_c"}, {"name": "Chitin monomer C8H13NO5", "notes": {"original_bigg_ids": ["chitin_c"]}, "charge": 0, "formula": "C8H13NO5", "compartment": "c", "id": "chitin_c"}, {"name": "Chitosan C6H11NO4", "notes": {"original_bigg_ids": ["chitos_c"]}, "charge": 0, "formula": "C6H11NO4", "compartment": "c", "id": "chitos_c"}, {"name": "UDP-N-acetyl-D-galactosamine", "notes": {"original_bigg_ids": ["udpacgal_c"]}, "charge": 0, "formula": "C17H25N3O17P2", "compartment": "c", "id": "udpacgal_c"}, {"name": "L-Malate", "notes": {"original_bigg_ids": ["mal_DASH_L_m"]}, "charge": 0, "formula": "C4H4O5", "compartment": "m", "id": "mal__L_m"}, {"name": "Citrate", "notes": {"original_bigg_ids": ["cit_x"]}, "charge": 0, "formula": "C6H5O7", "compartment": "x", "id": "cit_x"}, {"name": "L-Malate", "notes": {"original_bigg_ids": ["mal_DASH_L_x"]}, "charge": 0, "formula": "C4H4O5", "compartment": "x", "id": "mal__L_x"}, {"name": "Phosphoenolpyruvate", "notes": {"original_bigg_ids": ["pep_c"]}, "charge": 0, "formula": "C3H2O6P", "compartment": "c", "id": "pep_c"}, {"name": "Phosphoenolpyruvate", "notes": {"original_bigg_ids": ["pep_m"]}, "charge": 0, "formula": "C3H2O6P", "compartment": "m", "id": "pep_m"}, {"name": "Isocitrate", "notes": {"original_bigg_ids": ["icit_x"]}, "charge": 0, "formula": "C6H5O7", "compartment": "x", "id": "icit_x"}, {"name": "Cardiolipin yeast specific C7380H13688O1700P200", "notes": {"original_bigg_ids": ["clpn_SC_m"]}, "charge": 0, "formula": "C7380H13688O1700P200", "compartment": "m", "id": "clpn_SC_m"}, {"name": "Phosphatidylglycerol yeast specific C3840H7244O1000P100", "notes": {"original_bigg_ids": ["pg_SC_m"]}, "charge": 0, "formula": "C3840H7244O1000P100", "compartment": "m", "id": "pg_SC_m"}, {"name": "CMP", "notes": {"original_bigg_ids": ["cmp_c"]}, "charge": 0, "formula": "C9H12N3O8P", "compartment": "c", "id": "cmp_c"}, {"name": "Cytosine", "notes": {"original_bigg_ids": ["csn_c"]}, "charge": 0, "formula": "C4H5N3O", "compartment": "c", "id": "csn_c"}, {"name": "CO2", "notes": {"original_bigg_ids": ["co2_g"]}, "charge": 0, "formula": "CO2", "compartment": "g", "id": "co2_g"}, {"name": "CO2", "notes": {"original_bigg_ids": ["co2_n"]}, "charge": 0, "formula": "CO2", "compartment": "n", "id": "co2_n"}, {"name": "CO2", "notes": {"original_bigg_ids": ["co2_x"]}, "charge": 0, "formula": "CO2", "compartment": "x", "id": "co2_x"}, {"name": "CO2", "notes": {"original_bigg_ids": ["co2_v"]}, "charge": 0, "formula": "CO2", "compartment": "v", "id": "co2_v"}, {"name": "Protoporphyrinogen IX", "notes": {"original_bigg_ids": ["pppg9_c"]}, "charge": 0, "formula": "C34H38N4O4", "compartment": "c", "id": "pppg9_c"}, {"name": "Coproporphyrinogen III", "notes": {"original_bigg_ids": ["cpppg3_c"]}, "charge": 0, "formula": "C36H40N4O8", "compartment": "c", "id": "cpppg3_c"}, {"name": "L-Carnitine", "notes": {"original_bigg_ids": ["crn_m"]}, "charge": 0, "formula": "C7H15NO3", "compartment": "m", "id": "crn_m"}, {"name": "L-Carnitine", "notes": {"original_bigg_ids": ["crn_c"]}, "charge": 0, "formula": "C7H15NO3", "compartment": "c", "id": "crn_c"}, {"name": "L-Carnitine", "notes": {"original_bigg_ids": ["crn_x"]}, "charge": 0, "formula": "C7H15NO3", "compartment": "x", "id": "crn_x"}, {"name": "Uracil", "notes": {"original_bigg_ids": ["ura_c"]}, "charge": 0, "formula": "C4H4N2O2", "compartment": "c", "id": "ura_c"}, {"name": "UTP", "notes": {"original_bigg_ids": ["utp_c"]}, "charge": 0, "formula": "C9H11N2O15P3", "compartment": "c", "id": "utp_c"}, {"name": "O2", "notes": {"original_bigg_ids": ["o2_m"]}, "charge": 0, "formula": "O2", "compartment": "m", "id": "o2_m"}, {"name": "Ferricytochrome c C42H52FeN8O6S2", "notes": {"original_bigg_ids": ["ficytc_m"]}, "charge": 0, "formula": "C42H52FeN8O6S2", "compartment": "m", "id": "ficytc_m"}, {"name": "Ferrocytochrome c C42H53FeN8O6S2", "notes": {"original_bigg_ids": ["focytc_m"]}, "charge": 0, "formula": "C42H53FeN8O6S2", "compartment": "m", "id": "focytc_m"}, {"name": "Ubiquinol 6 C39H60O4", "notes": {"original_bigg_ids": ["q6h2_m"]}, "charge": 0, "formula": "C39H60O4", "compartment": "m", "id": "q6h2_m"}, {"name": "Ubiquinone 6 C39H58O4", "notes": {"original_bigg_ids": ["q6_m"]}, "charge": 0, "formula": "C39H58O4", "compartment": "m", "id": "q6_m"}, {"name": "L-Cysteine", "notes": {"original_bigg_ids": ["cys_DASH_L_c"]}, "charge": 0, "formula": "C3H7NO2S", "compartment": "c", "id": "cys__L_c"}, {"name": "O-Acetyl-L-serine", "notes": {"original_bigg_ids": ["acser_c"]}, "charge": 0, "formula": "C5H9NO4", "compartment": "c", "id": "acser_c"}, {"name": "L-Cystathionine", "notes": {"original_bigg_ids": ["cyst_DASH_L_c"]}, "charge": 0, "formula": "C7H14N2O4S", "compartment": "c", "id": "cyst__L_c"}, {"name": "2-Oxobutanoate", "notes": {"original_bigg_ids": ["2obut_c"]}, "charge": 0, "formula": "C4H5O3", "compartment": "c", "id": "2obut_c"}, {"name": "L-Cystathionine", "notes": {"original_bigg_ids": ["cyst_DASH_L_x"]}, "charge": 0, "formula": "C7H14N2O4S", "compartment": "x", "id": "cyst__L_x"}, {"name": "Pyruvate", "notes": {"original_bigg_ids": ["pyr_x"]}, "charge": 0, "formula": "C3H3O3", "compartment": "x", "id": "pyr_x"}, {"name": "L-Homocysteine", "notes": {"original_bigg_ids": ["hcys_DASH_L_x"]}, "charge": 0, "formula": "C4H9NO2S", "compartment": "x", "id": "hcys__L_x"}, {"name": "Ammonium", "notes": {"original_bigg_ids": ["nh4_x"]}, "charge": 0, "formula": "H4N", "compartment": "x", "id": "nh4_x"}, {"name": "L-Cysteinyl-tRNA(Cys)", "notes": {"original_bigg_ids": ["cystrna_c"]}, "charge": 0, "formula": "C3H6NOSR", "compartment": "c", "id": "cystrna_c"}, {"name": "TRNA(Cys)", "notes": {"original_bigg_ids": ["trnacys_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnacys_c"}, {"name": "L-Serine", "notes": {"original_bigg_ids": ["ser_DASH_L_c"]}, "charge": 0, "formula": "C3H7NO3", "compartment": "c", "id": "ser__L_c"}, {"name": "Cytidine", "notes": {"original_bigg_ids": ["cytd_c"]}, "charge": 0, "formula": "C9H13N3O5", "compartment": "c", "id": "cytd_c"}, {"name": "Uridine", "notes": {"original_bigg_ids": ["uri_c"]}, "charge": 0, "formula": "C9H12N2O6", "compartment": "c", "id": "uri_c"}, {"name": "DCDP", "notes": {"original_bigg_ids": ["dcdp_c"]}, "charge": 0, "formula": "C9H12N3O10P2", "compartment": "c", "id": "dcdp_c"}, {"name": "DCMP", "notes": {"original_bigg_ids": ["dcmp_c"]}, "charge": 0, "formula": "C9H12N3O7P", "compartment": "c", "id": "dcmp_c"}, {"name": "Deoxyinosine", "notes": {"original_bigg_ids": ["din_c"]}, "charge": 0, "formula": "C10H12N4O4", "compartment": "c", "id": "din_c"}, {"name": "Deoxyadenosine", "notes": {"original_bigg_ids": ["dad_DASH_2_c"]}, "charge": 0, "formula": "C10H13N5O3", "compartment": "c", "id": "dad_2_c"}, {"name": "DAMP", "notes": {"original_bigg_ids": ["damp_c"]}, "charge": 0, "formula": "C10H12N5O6P", "compartment": "c", "id": "damp_c"}, {"name": "DADP", "notes": {"original_bigg_ids": ["dadp_c"]}, "charge": 0, "formula": "C10H12N5O9P2", "compartment": "c", "id": "dadp_c"}, {"name": "DADP", "notes": {"original_bigg_ids": ["dadp_n"]}, "charge": 0, "formula": "C10H12N5O9P2", "compartment": "n", "id": "dadp_n"}, {"name": "1 2 Diacylglycerol yeast specific C3540H6644O500", "notes": {"original_bigg_ids": ["12dgr_SC_c"]}, "charge": 0, "formula": "C3540H6644O500", "compartment": "c", "id": "12dgr_SC_c"}, {"name": "Phosphatidylcholine yeast specific C4040H7844N100O800P100", "notes": {"original_bigg_ids": ["pc_SC_c"]}, "charge": 0, "formula": "C4040H7844N100O800P100", "compartment": "c", "id": "pc_SC_c"}, {"name": "CDPdiacylglycerol yeast specific C4440H7744N300O1500P200", "notes": {"original_bigg_ids": ["cdpdag_SC_c"]}, "charge": 0, "formula": "C4440H7744N300O1500P200", "compartment": "c", "id": "cdpdag_SC_c"}, {"name": "Phosphatidate yeast specific C3540H6544O800P100", "notes": {"original_bigg_ids": ["pa_SC_m"]}, "charge": 0, "formula": "C3540H6544O800P100", "compartment": "m", "id": "pa_SC_m"}, {"name": "CTP", "notes": {"original_bigg_ids": ["ctp_m"]}, "charge": 0, "formula": "C9H12N3O14P3", "compartment": "m", "id": "ctp_m"}, {"name": "D-Ribulose 5-phosphate", "notes": {"original_bigg_ids": ["ru5p_DASH_D_c"]}, "charge": 0, "formula": "C5H9O8P", "compartment": "c", "id": "ru5p__D_c"}, {"name": "3,4-dihydroxy-2-butanone 4-phosphate", "notes": {"original_bigg_ids": ["db4p_c"]}, "charge": 0, "formula": "C4H7O6P", "compartment": "c", "id": "db4p_c"}, {"name": "Formate", "notes": {"original_bigg_ids": ["for_c"]}, "charge": 0, "formula": "CH1O2", "compartment": "c", "id": "for_c"}, {"name": "DCDP", "notes": {"original_bigg_ids": ["dcdp_n"]}, "charge": 0, "formula": "C9H12N3O10P2", "compartment": "n", "id": "dcdp_n"}, {"name": "DUMP", "notes": {"original_bigg_ids": ["dump_c"]}, "charge": 0, "formula": "C9H11N2O8P", "compartment": "c", "id": "dump_c"}, {"name": "DUTP", "notes": {"original_bigg_ids": ["dutp_c"]}, "charge": 0, "formula": "C9H11N2O14P3", "compartment": "c", "id": "dutp_c"}, {"name": "DCTP", "notes": {"original_bigg_ids": ["dctp_c"]}, "charge": 0, "formula": "C9H12N3O13P3", "compartment": "c", "id": "dctp_c"}, {"name": "Deoxyuridine", "notes": {"original_bigg_ids": ["duri_c"]}, "charge": 0, "formula": "C9H12N2O5", "compartment": "c", "id": "duri_c"}, {"name": "Deoxycytidine", "notes": {"original_bigg_ids": ["dcyt_c"]}, "charge": 0, "formula": "C9H13N3O4", "compartment": "c", "id": "dcyt_c"}, {"name": "D-Erythrose 4-phosphate", "notes": {"original_bigg_ids": ["e4p_c"]}, "charge": 0, "formula": "C4H7O7P", "compartment": "c", "id": "e4p_c"}, {"name": "D-Erythrose 4-phosphate", "notes": {"original_bigg_ids": ["e4p_m"]}, "charge": 0, "formula": "C4H7O7P", "compartment": "m", "id": "e4p_m"}, {"name": "DGDP", "notes": {"original_bigg_ids": ["dgdp_c"]}, "charge": 0, "formula": "C10H12N5O10P2", "compartment": "c", "id": "dgdp_c"}, {"name": "DGDP", "notes": {"original_bigg_ids": ["dgdp_n"]}, "charge": 0, "formula": "C10H12N5O10P2", "compartment": "n", "id": "dgdp_n"}, {"name": "D-Galactose", "notes": {"original_bigg_ids": ["gal_c"]}, "charge": 0, "formula": "C6H12O6", "compartment": "c", "id": "gal_c"}, {"name": "D Gal alpha 1 6D Glucose C12H22O11", "notes": {"original_bigg_ids": ["6dg_c"]}, "charge": 0, "formula": "C12H22O11", "compartment": "c", "id": "6dg_c"}, {"name": "DGMP", "notes": {"original_bigg_ids": ["dgmp_c"]}, "charge": 0, "formula": "C10H12N5O7P", "compartment": "c", "id": "dgmp_c"}, {"name": "Deoxyguanosine", "notes": {"original_bigg_ids": ["dgsn_c"]}, "charge": 0, "formula": "C10H13N5O4", "compartment": "c", "id": "dgsn_c"}, {"name": "(R)-2,3-Dihydroxy-3-methylbutanoate", "notes": {"original_bigg_ids": ["23dhmb_m"]}, "charge": 0, "formula": "C5H9O4", "compartment": "m", "id": "23dhmb_m"}, {"name": "(R)-2,3-Dihydroxy-3-methylpentanoate", "notes": {"original_bigg_ids": ["23dhmp_m"]}, "charge": 0, "formula": "C6H11O4", "compartment": "m", "id": "23dhmp_m"}, {"name": "Dihydroxyacetone phosphate", "notes": {"original_bigg_ids": ["dhap_c"]}, "charge": 0, "formula": "C3H5O6P", "compartment": "c", "id": "dhap_c"}, {"name": "Dihydroxyacetone", "notes": {"original_bigg_ids": ["dha_c"]}, "charge": 0, "formula": "C3H6O3", "compartment": "c", "id": "dha_c"}, {"name": "Dihydroxyacetone phosphate", "notes": {"original_bigg_ids": ["dhap_m"]}, "charge": 0, "formula": "C3H5O6P", "compartment": "m", "id": "dhap_m"}, {"name": "7,8-Dihydrofolate", "notes": {"original_bigg_ids": ["dhf_c"]}, "charge": 0, "formula": "C19H19N7O6", "compartment": "c", "id": "dhf_c"}, {"name": "7,8-Dihydrofolate", "notes": {"original_bigg_ids": ["dhf_m"]}, "charge": 0, "formula": "C19H19N7O6", "compartment": "m", "id": "dhf_m"}, {"name": "5,6,7,8-Tetrahydrofolate", "notes": {"original_bigg_ids": ["thf_m"]}, "charge": 0, "formula": "C19H21N7O6", "compartment": "m", "id": "thf_m"}, {"name": "Dihydropteroate", "notes": {"original_bigg_ids": ["dhpt_c"]}, "charge": 0, "formula": "C14H13N6O3", "compartment": "c", "id": "dhpt_c"}, {"name": "Dihydroneopterin", "notes": {"original_bigg_ids": ["dhnpt_m"]}, "charge": 0, "formula": "C9H13N5O4", "compartment": "m", "id": "dhnpt_m"}, {"name": "2 Amino 4 hydroxy 6 hydroxymethyl 7 8 dihydropteridine C7H9N5O2", "notes": {"original_bigg_ids": ["2ahhmp_m"]}, "charge": 0, "formula": "C7H9N5O2", "compartment": "m", "id": "2ahhmp_m"}, {"name": "Glycolaldehyde", "notes": {"original_bigg_ids": ["gcald_m"]}, "charge": 0, "formula": "C2H4O2", "compartment": "m", "id": "gcald_m"}, {"name": "(S)-Dihydroorotate", "notes": {"original_bigg_ids": ["dhor_DASH_S_c"]}, "charge": 0, "formula": "C5H5N2O4", "compartment": "c", "id": "dhor__S_c"}, {"name": "Orotate", "notes": {"original_bigg_ids": ["orot_c"]}, "charge": 0, "formula": "C5H3N2O4", "compartment": "c", "id": "orot_c"}, {"name": "(S)-Dihydroorotate", "notes": {"original_bigg_ids": ["dhor_DASH_S_n"]}, "charge": 0, "formula": "C5H5N2O4", "compartment": "n", "id": "dhor__S_n"}, {"name": "2 5 Diamino 6 hydroxy 4 5 phosphoribosylamino pyrimidine C9H14N5O8P", "notes": {"original_bigg_ids": ["25dhpp_c"]}, "charge": 0, "formula": "C9H14N5O8P", "compartment": "c", "id": "25dhpp_c"}, {"name": "Dihydropteroate", "notes": {"original_bigg_ids": ["dhpt_m"]}, "charge": 0, "formula": "C14H13N6O3", "compartment": "m", "id": "dhpt_m"}, {"name": "3-Dehydroquinate", "notes": {"original_bigg_ids": ["3dhq_c"]}, "charge": 0, "formula": "C7H9O6", "compartment": "c", "id": "3dhq_c"}, {"name": "3-Dehydroshikimate", "notes": {"original_bigg_ids": ["3dhsk_c"]}, "charge": 0, "formula": "C7H7O5", "compartment": "c", "id": "3dhsk_c"}, {"name": "Spermine C10H30N4", "notes": {"original_bigg_ids": ["sprm_c"]}, "charge": 0, "formula": "C10H30N4", "compartment": "c", "id": "sprm_c"}, {"name": "N1 Acetylspermine C12H31N4O", "notes": {"original_bigg_ids": ["N1sprm_c"]}, "charge": 0, "formula": "C12H31N4O", "compartment": "c", "id": "N1sprm_c"}, {"name": "Succinate", "notes": {"original_bigg_ids": ["succ_m"]}, "charge": 0, "formula": "C4H4O4", "compartment": "m", "id": "succ_m"}, {"name": "Succinate", "notes": {"original_bigg_ids": ["succ_c"]}, "charge": 0, "formula": "C4H4O4", "compartment": "c", "id": "succ_c"}, {"name": "2 3 Carboxy 3 aminopropyl L histidine C10H16N4O4", "notes": {"original_bigg_ids": ["caphis_c"]}, "charge": 0, "formula": "C10H16N4O4", "compartment": "c", "id": "caphis_c"}, {"name": "2 3 Carboxy 3 methylammonio propyl L histidine C11H18N4O4", "notes": {"original_bigg_ids": ["cmaphis_c"]}, "charge": 0, "formula": "C11H18N4O4", "compartment": "c", "id": "cmaphis_c"}, {"name": "Geranyl diphosphate", "notes": {"original_bigg_ids": ["grdp_c"]}, "charge": 0, "formula": "C10H17O7P2", "compartment": "c", "id": "grdp_c"}, {"name": "2-Octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol (5 repeating units)", "notes": {"original_bigg_ids": ["2omhmbl_5_m"]}, "charge": 0, "formula": "C38H58O4", "compartment": "m", "id": "2omhmbl_5_m"}, {"name": "Dihydroneopterin monophosphate", "notes": {"original_bigg_ids": ["dhpmp_c"]}, "charge": 0, "formula": "C9H12N5O7P", "compartment": "c", "id": "dhpmp_c"}, {"name": "Dolichol phosphate C15H27O4P", "notes": {"original_bigg_ids": ["dolp_c"]}, "charge": 0, "formula": "C15H27O4P", "compartment": "c", "id": "dolp_c"}, {"name": "Dolichol C15H28O", "notes": {"original_bigg_ids": ["dolichol_c"]}, "charge": 0, "formula": "C15H28O", "compartment": "c", "id": "dolichol_c"}, {"name": "Dolichol phosphate C15H27O4P", "notes": {"original_bigg_ids": ["dolp_r"]}, "charge": 0, "formula": "C15H27O4P", "compartment": "r", "id": "dolp_r"}, {"name": "Dolichyl phosphate D mannose C21H38O9P", "notes": {"original_bigg_ids": ["dolmanp_r"]}, "charge": 0, "formula": "C21H38O9P", "compartment": "r", "id": "dolmanp_r"}, {"name": "Mannan C6H10O5", "notes": {"original_bigg_ids": ["mannan_r"]}, "charge": 0, "formula": "C6H10O5", "compartment": "r", "id": "mannan_r"}, {"name": "GDP-D-mannose", "notes": {"original_bigg_ids": ["gdpmann_c"]}, "charge": 0, "formula": "C16H23N5O16P2", "compartment": "c", "id": "gdpmann_c"}, {"name": "Dephospho-CoA", "notes": {"original_bigg_ids": ["dpcoa_c"]}, "charge": 0, "formula": "C21H33N7O13P2S", "compartment": "c", "id": "dpcoa_c"}, {"name": "Dephospho-CoA", "notes": {"original_bigg_ids": ["dpcoa_m"]}, "charge": 0, "formula": "C21H33N7O13P2S", "compartment": "m", "id": "dpcoa_m"}, {"name": "3-Phospho-D-glyceroyl phosphate", "notes": {"original_bigg_ids": ["13dpg_c"]}, "charge": 0, "formula": "C3H4O10P2", "compartment": "c", "id": "13dpg_c"}, {"name": "2 3 Disphospho D glycerate C3H3O10P2", "notes": {"original_bigg_ids": ["23dpg_c"]}, "charge": 0, "formula": "C3H3O10P2", "compartment": "c", "id": "23dpg_c"}, {"name": " R 5 Diphosphomevalonate C6H10O10P2", "notes": {"original_bigg_ids": ["5dpmev_c"]}, "charge": 0, "formula": "C6H10O10P2", "compartment": "c", "id": "5dpmev_c"}, {"name": "(R)-Pantoate", "notes": {"original_bigg_ids": ["pant_DASH_R_c"]}, "charge": 0, "formula": "C6H11O4", "compartment": "c", "id": "pant__R_c"}, {"name": "(R)-Pantoate", "notes": {"original_bigg_ids": ["pant_DASH_R_m"]}, "charge": 0, "formula": "C6H11O4", "compartment": "m", "id": "pant__R_m"}, {"name": "2-Deoxy-D-ribose 5-phosphate", "notes": {"original_bigg_ids": ["2dr5p_c"]}, "charge": 0, "formula": "C5H9O7P", "compartment": "c", "id": "2dr5p_c"}, {"name": "Deoxyribose C5H10O4", "notes": {"original_bigg_ids": ["drib_c"]}, "charge": 0, "formula": "C5H10O4", "compartment": "c", "id": "drib_c"}, {"name": "DTDP", "notes": {"original_bigg_ids": ["dtdp_c"]}, "charge": 0, "formula": "C10H13N2O11P2", "compartment": "c", "id": "dtdp_c"}, {"name": "DTMP", "notes": {"original_bigg_ids": ["dtmp_c"]}, "charge": 0, "formula": "C10H13N2O8P", "compartment": "c", "id": "dtmp_c"}, {"name": "DTTP", "notes": {"original_bigg_ids": ["dttp_c"]}, "charge": 0, "formula": "C10H13N2O14P3", "compartment": "c", "id": "dttp_c"}, {"name": "DUMP", "notes": {"original_bigg_ids": ["dump_n"]}, "charge": 0, "formula": "C9H11N2O8P", "compartment": "n", "id": "dump_n"}, {"name": "2-Deoxy-D-ribose 1-phosphate", "notes": {"original_bigg_ids": ["2dr1p_c"]}, "charge": 0, "formula": "C5H9O7P", "compartment": "c", "id": "2dr1p_c"}, {"name": "Spermidine", "notes": {"original_bigg_ids": ["spmd_c"]}, "charge": 0, "formula": "C7H22N3", "compartment": "c", "id": "spmd_c"}, {"name": "1 3 Diaminopropane C3H12N2", "notes": {"original_bigg_ids": ["13dampp_c"]}, "charge": 0, "formula": "C3H12N2", "compartment": "c", "id": "13dampp_c"}, {"name": "D-Lactate", "notes": {"original_bigg_ids": ["lac_DASH_D_m"]}, "charge": 0, "formula": "C3H5O3", "compartment": "m", "id": "lac__D_m"}, {"name": "D-Lactate", "notes": {"original_bigg_ids": ["lac_DASH_D_c"]}, "charge": 0, "formula": "C3H5O3", "compartment": "c", "id": "lac__D_c"}, {"name": "L erythro 4 Hydroxyglutamate C5H8NO5", "notes": {"original_bigg_ids": ["e4hglu_c"]}, "charge": 0, "formula": "C5H8NO5", "compartment": "c", "id": "e4hglu_c"}, {"name": "L erythro 4 Hydroxyglutamate C5H8NO5", "notes": {"original_bigg_ids": ["e4hglu_x"]}, "charge": 0, "formula": "C5H8NO5", "compartment": "x", "id": "e4hglu_x"}, {"name": " S 3 Hydroxyhexacosyl CoA C47H82N7O18P3S", "notes": {"original_bigg_ids": ["3hxccoa_x"]}, "charge": 0, "formula": "C47H82N7O18P3S", "compartment": "x", "id": "3hxccoa_x"}, {"name": "(S)-3-Hydroxydecanoyl-CoA", "notes": {"original_bigg_ids": ["3hdcoa_x"]}, "charge": 0, "formula": "C31H50N7O18P3S", "compartment": "x", "id": "3hdcoa_x"}, {"name": "(S)-3-Hydroxydodecanoyl-CoA", "notes": {"original_bigg_ids": ["3hddcoa_x"]}, "charge": 0, "formula": "C33H54N7O18P3S", "compartment": "x", "id": "3hddcoa_x"}, {"name": "(S)-3-Hydroxytetradecanoyl-CoA", "notes": {"original_bigg_ids": ["3htdcoa_x"]}, "charge": 0, "formula": "C35H58N7O18P3S", "compartment": "x", "id": "3htdcoa_x"}, {"name": "(S)-3-Hydroxyhexadecanoyl-CoA", "notes": {"original_bigg_ids": ["3hhdcoa_x"]}, "charge": 0, "formula": "C37H62N7O18P3S", "compartment": "x", "id": "3hhdcoa_x"}, {"name": "(S)-3-Hydroxyoctadecanoyl-CoA", "notes": {"original_bigg_ids": ["3hodcoa_x"]}, "charge": 0, "formula": "C39H66N7O18P3S", "compartment": "x", "id": "3hodcoa_x"}, {"name": "D-Glycerate 2-phosphate", "notes": {"original_bigg_ids": ["2pg_c"]}, "charge": 0, "formula": "C3H4O7P", "compartment": "c", "id": "2pg_c"}, {"name": "D-Mannose", "notes": {"original_bigg_ids": ["man_c"]}, "charge": 0, "formula": "C6H12O6", "compartment": "c", "id": "man_c"}, {"name": "Epimelibiose C12H22O11", "notes": {"original_bigg_ids": ["epm_c"]}, "charge": 0, "formula": "C12H22O11", "compartment": "c", "id": "epm_c"}, {"name": "Ergosterol C28H44O", "notes": {"original_bigg_ids": ["ergst_c"]}, "charge": 0, "formula": "C28H44O", "compartment": "c", "id": "ergst_c"}, {"name": "Ethanolamine", "notes": {"original_bigg_ids": ["etha_c"]}, "charge": 0, "formula": "C2H8NO", "compartment": "c", "id": "etha_c"}, {"name": "Ethanolamine phosphate C2H7NO4P", "notes": {"original_bigg_ids": ["ethamp_c"]}, "charge": 0, "formula": "C2H7NO4P", "compartment": "c", "id": "ethamp_c"}, {"name": "CDPethanolamine C11H19N4O11P2", "notes": {"original_bigg_ids": ["cdpea_c"]}, "charge": 0, "formula": "C11H19N4O11P2", "compartment": "c", "id": "cdpea_c"}, {"name": "Phosphatidylethanolamine yeast specific C3740H7244N100O800P100", "notes": {"original_bigg_ids": ["pe_SC_c"]}, "charge": 0, "formula": "C3740H7244N100O800P100", "compartment": "c", "id": "pe_SC_c"}, {"name": "Octadecynoyl CoA n C182CoA C39H62N7O17P3S", "notes": {"original_bigg_ids": ["ocdycacoa_x"]}, "charge": 0, "formula": "C39H62N7O17P3S", "compartment": "x", "id": "ocdycacoa_x"}, {"name": "Tetracosanoate n C240 C24H47O2", "notes": {"original_bigg_ids": ["ttc_x"]}, "charge": 0, "formula": "C24H47O2", "compartment": "x", "id": "ttc_x"}, {"name": "Tetracosanoate n C240 C24H47O2", "notes": {"original_bigg_ids": ["ttc_c"]}, "charge": 0, "formula": "C24H47O2", "compartment": "c", "id": "ttc_c"}, {"name": "Hexacosanoate n C260 C26H51O2", "notes": {"original_bigg_ids": ["hexc_x"]}, "charge": 0, "formula": "C26H51O2", "compartment": "x", "id": "hexc_x"}, {"name": "Hexacosanoate n C260 C26H51O2", "notes": {"original_bigg_ids": ["hexc_c"]}, "charge": 0, "formula": "C26H51O2", "compartment": "c", "id": "hexc_c"}, {"name": "Octanoate (n-C8:0)", "notes": {"original_bigg_ids": ["octa_c"]}, "charge": 0, "formula": "C8H15O2", "compartment": "c", "id": "octa_c"}, {"name": "Octanoate (n-C8:0)", "notes": {"original_bigg_ids": ["octa_x"]}, "charge": 0, "formula": "C8H15O2", "compartment": "x", "id": "octa_x"}, {"name": "FMN", "notes": {"original_bigg_ids": ["fmn_m"]}, "charge": 0, "formula": "C17H19N4O9P", "compartment": "m", "id": "fmn_m"}, {"name": "FMN", "notes": {"original_bigg_ids": ["fmn_c"]}, "charge": 0, "formula": "C17H19N4O9P", "compartment": "c", "id": "fmn_c"}, {"name": "Flavin adenine dinucleotide oxidized", "notes": {"original_bigg_ids": ["fad_c"]}, "charge": 0, "formula": "C27H31N9O15P2", "compartment": "c", "id": "fad_c"}, {"name": "S-Formylglutathione", "notes": {"original_bigg_ids": ["Sfglutth_c"]}, "charge": 0, "formula": "C11H16N3O7S", "compartment": "c", "id": "Sfglutth_c"}, {"name": "Formaldehyde", "notes": {"original_bigg_ids": ["fald_c"]}, "charge": 0, "formula": "CH2O", "compartment": "c", "id": "fald_c"}, {"name": "Reduced glutathione", "notes": {"original_bigg_ids": ["gthrd_c"]}, "charge": 0, "formula": "C10H16N3O6S", "compartment": "c", "id": "gthrd_c"}, {"name": "Nicotinamide adenine dinucleotide phosphate", "notes": {"original_bigg_ids": ["nadp_x"]}, "charge": 0, "formula": "C21H25N7O17P3", "compartment": "x", "id": "nadp_x"}, {"name": "Nicotinamide adenine dinucleotide - reduced", "notes": {"original_bigg_ids": ["nadh_x"]}, "charge": 0, "formula": "C21H27N7O14P2", "compartment": "x", "id": "nadh_x"}, {"name": "Nicotinamide adenine dinucleotide", "notes": {"original_bigg_ids": ["nad_x"]}, "charge": 0, "formula": "C21H26N7O14P2", "compartment": "x", "id": "nad_x"}, {"name": "Nicotinamide adenine dinucleotide phosphate - reduced", "notes": {"original_bigg_ids": ["nadph_x"]}, "charge": 0, "formula": "C21H26N7O17P3", "compartment": "x", "id": "nadph_x"}, {"name": "Malonyl-[acyl-carrier protein]", "notes": {"original_bigg_ids": ["malACP_m"]}, "charge": 0, "formula": "C14H22N2O10PRS", "compartment": "m", "id": "malACP_m"}, {"name": "Octanoyl-ACP (n-C8:0ACP)", "notes": {"original_bigg_ids": ["ocACP_m"]}, "charge": 0, "formula": "C19H35N2O8PRS", "compartment": "m", "id": "ocACP_m"}, {"name": "Decanoyl-ACP (n-C10:0ACP)", "notes": {"original_bigg_ids": ["dcaACP_m"]}, "charge": 0, "formula": "C21H39N2O8PRS", "compartment": "m", "id": "dcaACP_m"}, {"name": "Octanoyl-CoA (n-C8:0CoA)", "notes": {"original_bigg_ids": ["occoa_c"]}, "charge": 0, "formula": "C29H46N7O17P3S", "compartment": "c", "id": "occoa_c"}, {"name": "5,10-Methenyltetrahydrofolate", "notes": {"original_bigg_ids": ["methf_c"]}, "charge": 0, "formula": "C20H20N7O6", "compartment": "c", "id": "methf_c"}, {"name": "5-Formyltetrahydrofolate", "notes": {"original_bigg_ids": ["5fthf_c"]}, "charge": 0, "formula": "C20H21N7O7", "compartment": "c", "id": "5fthf_c"}, {"name": "D-Fructose 1,6-bisphosphate", "notes": {"original_bigg_ids": ["fdp_c"]}, "charge": 0, "formula": "C6H10O12P2", "compartment": "c", "id": "fdp_c"}, {"name": "Glyceraldehyde 3-phosphate", "notes": {"original_bigg_ids": ["g3p_c"]}, "charge": 0, "formula": "C3H5O6P", "compartment": "c", "id": "g3p_c"}, {"name": "D-Fructose 1-phosphate", "notes": {"original_bigg_ids": ["f1p_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "f1p_c"}, {"name": "Sedoheptulose 1,7-bisphosphate", "notes": {"original_bigg_ids": ["s17bp_c"]}, "charge": 0, "formula": "C7H12O13P2", "compartment": "c", "id": "s17bp_c"}, {"name": "D-Fructose 6-phosphate", "notes": {"original_bigg_ids": ["f6p_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "f6p_c"}, {"name": "D Fructose 2 6 bisphosphate C6H10O12P2", "notes": {"original_bigg_ids": ["f26bp_c"]}, "charge": 0, "formula": "C6H10O12P2", "compartment": "c", "id": "f26bp_c"}, {"name": "Fe2+", "notes": {"original_bigg_ids": ["fe2_m"]}, "charge": 0, "formula": "Fe", "compartment": "m", "id": "fe2_m"}, {"name": "Protoheme", "notes": {"original_bigg_ids": ["pheme_m"]}, "charge": 0, "formula": "C34H30FeN4O4", "compartment": "m", "id": "pheme_m"}, {"name": "Protoporphyrin", "notes": {"original_bigg_ids": ["ppp9_m"]}, "charge": 0, "formula": "C34H32N4O4", "compartment": "m", "id": "ppp9_m"}, {"name": "L Kynurenine C10H12N2O3", "notes": {"original_bigg_ids": ["Lkynr_c"]}, "charge": 0, "formula": "C10H12N2O3", "compartment": "c", "id": "Lkynr_c"}, {"name": "L Formylkynurenine C11H12N2O4", "notes": {"original_bigg_ids": ["Lfmkynr_c"]}, "charge": 0, "formula": "C11H12N2O4", "compartment": "c", "id": "Lfmkynr_c"}, {"name": "L-Methionyl-tRNA (Met)", "notes": {"original_bigg_ids": ["mettrna_m"]}, "charge": 0, "formula": "C5H10NOSR", "compartment": "m", "id": "mettrna_m"}, {"name": "N-Formylmethionyl-tRNA", "notes": {"original_bigg_ids": ["fmettrna_m"]}, "charge": 0, "formula": "C6H9NO2SR", "compartment": "m", "id": "fmettrna_m"}, {"name": "10-Formyltetrahydrofolate", "notes": {"original_bigg_ids": ["10fthf_m"]}, "charge": 0, "formula": "C20H21N7O7", "compartment": "m", "id": "10fthf_m"}, {"name": "2 Amino 4 hydroxy 6 hydroxymethyl 7 8 dihydropteridine diphosphate C7H8N5O8P2", "notes": {"original_bigg_ids": ["2ahhmd_m"]}, "charge": 0, "formula": "C7H8N5O8P2", "compartment": "m", "id": "2ahhmd_m"}, {"name": "Formate", "notes": {"original_bigg_ids": ["for_m"]}, "charge": 0, "formula": "CH1O2", "compartment": "m", "id": "for_m"}, {"name": "Fumarate", "notes": {"original_bigg_ids": ["fum_m"]}, "charge": 0, "formula": "C4H2O4", "compartment": "m", "id": "fum_m"}, {"name": "D-Fructose", "notes": {"original_bigg_ids": ["fru_c"]}, "charge": 0, "formula": "C6H12O6", "compartment": "c", "id": "fru_c"}, {"name": "5-Formyltetrahydrofolate", "notes": {"original_bigg_ids": ["5fthf_m"]}, "charge": 0, "formula": "C20H21N7O7", "compartment": "m", "id": "5fthf_m"}, {"name": "5,10-Methenyltetrahydrofolate", "notes": {"original_bigg_ids": ["methf_m"]}, "charge": 0, "formula": "C20H20N7O6", "compartment": "m", "id": "methf_m"}, {"name": "Acetoacetate", "notes": {"original_bigg_ids": ["acac_c"]}, "charge": 0, "formula": "C4H5O3", "compartment": "c", "id": "acac_c"}, {"name": "4 Fumarylacetoacetate C8H6O6", "notes": {"original_bigg_ids": ["4fumacac_c"]}, "charge": 0, "formula": "C8H6O6", "compartment": "c", "id": "4fumacac_c"}, {"name": " alpha D mannosyl 2 beta D mannosyl diacetylchitobiosyldiphosphodolichol C49H84N2O32P2", "notes": {"original_bigg_ids": ["m2macchitppdol_g"]}, "charge": 0, "formula": "C49H84N2O32P2", "compartment": "g", "id": "m2macchitppdol_g"}, {"name": "GDP-D-mannose", "notes": {"original_bigg_ids": ["gdpmann_g"]}, "charge": 0, "formula": "C16H23N5O16P2", "compartment": "g", "id": "gdpmann_g"}, {"name": " alpha D mannosyl 3 beta D mannosyl diacetylchitodiphosphodolichol C55H94N2O37P2", "notes": {"original_bigg_ids": ["m3macchitppdol_g"]}, "charge": 0, "formula": "C55H94N2O37P2", "compartment": "g", "id": "m3macchitppdol_g"}, {"name": "GDP", "notes": {"original_bigg_ids": ["gdp_g"]}, "charge": 0, "formula": "C10H12N5O11P2", "compartment": "g", "id": "gdp_g"}, {"name": " alpha D Mannosyl 4 beta D mannosyl diacetylchitobiosyldiphosphodolichol C61H104N2O42P2", "notes": {"original_bigg_ids": ["m4macchitppdol_g"]}, "charge": 0, "formula": "C61H104N2O42P2", "compartment": "g", "id": "m4macchitppdol_g"}, {"name": "Beta D Mannosyldiacetylchitobiosyldiphosphodolichol C37H64N2O22P2", "notes": {"original_bigg_ids": ["macchitppdol_g"]}, "charge": 0, "formula": "C37H64N2O22P2", "compartment": "g", "id": "macchitppdol_g"}, {"name": "Alpha D mannosyl beta D mannosyl diacylchitobiosyldiphosphodolichol C43H74N2O27P2", "notes": {"original_bigg_ids": ["m1macchitppdol_g"]}, "charge": 0, "formula": "C43H74N2O27P2", "compartment": "g", "id": "m1macchitppdol_g"}, {"name": "Glycerol 3-phosphate", "notes": {"original_bigg_ids": ["glyc3p_c"]}, "charge": 0, "formula": "C3H7O6P", "compartment": "c", "id": "glyc3p_c"}, {"name": "1-Pyrroline-5-carboxylate", "notes": {"original_bigg_ids": ["1pyr5c_c"]}, "charge": 0, "formula": "C5H6NO2", "compartment": "c", "id": "1pyr5c_c"}, {"name": "L-Glutamate 5-semialdehyde", "notes": {"original_bigg_ids": ["glu5sa_c"]}, "charge": 0, "formula": "C5H9NO3", "compartment": "c", "id": "glu5sa_c"}, {"name": "L-Glutamate 5-semialdehyde", "notes": {"original_bigg_ids": ["glu5sa_m"]}, "charge": 0, "formula": "C5H9NO3", "compartment": "m", "id": "glu5sa_m"}, {"name": "1-Pyrroline-5-carboxylate", "notes": {"original_bigg_ids": ["1pyr5c_m"]}, "charge": 0, "formula": "C5H6NO2", "compartment": "m", "id": "1pyr5c_m"}, {"name": "L-Glutamate 5-phosphate", "notes": {"original_bigg_ids": ["glu5p_c"]}, "charge": 0, "formula": "C5H8NO7P", "compartment": "c", "id": "glu5p_c"}, {"name": "D-Glucose 6-phosphate", "notes": {"original_bigg_ids": ["g6p_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "g6p_c"}, {"name": "D-Glucose 6-phosphate", "notes": {"original_bigg_ids": ["g6p_r"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "r", "id": "g6p_r"}, {"name": "Beta D glucose 6 phosphate C6H11O9P", "notes": {"original_bigg_ids": ["g6p_DASH_B_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "g6p_B_c"}, {"name": "Beta-D-Fructose 6-phosphate", "notes": {"original_bigg_ids": ["f6p_DASH_B_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "f6p_B_c"}, {"name": "1 alpha D Galactosyl myo inositol C12H22O11", "notes": {"original_bigg_ids": ["1Dgali_c"]}, "charge": 0, "formula": "C12H22O11", "compartment": "c", "id": "1Dgali_c"}, {"name": "Myo-Inositol", "notes": {"original_bigg_ids": ["inost_c"]}, "charge": 0, "formula": "C6H12O6", "compartment": "c", "id": "inost_c"}, {"name": "Alpha-D-Galactose 1-phosphate", "notes": {"original_bigg_ids": ["gal1p_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "gal1p_c"}, {"name": "Melibiose", "notes": {"original_bigg_ids": ["melib_c"]}, "charge": 0, "formula": "C12H22O11", "compartment": "c", "id": "melib_c"}, {"name": "UDPgalactose", "notes": {"original_bigg_ids": ["udpgal_c"]}, "charge": 0, "formula": "C15H22N2O17P2", "compartment": "c", "id": "udpgal_c"}, {"name": "D-Glucose 1-phosphate", "notes": {"original_bigg_ids": ["g1p_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "g1p_c"}, {"name": "N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide", "notes": {"original_bigg_ids": ["fgam_c"]}, "charge": 0, "formula": "C8H13N2O9P", "compartment": "c", "id": "fgam_c"}, {"name": "N1-(5-Phospho-D-ribosyl)glycinamide", "notes": {"original_bigg_ids": ["gar_c"]}, "charge": 0, "formula": "C7H14N2O8P", "compartment": "c", "id": "gar_c"}, {"name": " 1 4 alpha D Glucosyl n C6H12O6", "notes": {"original_bigg_ids": ["14glun_c"]}, "charge": 0, "formula": "C6H12O6", "compartment": "c", "id": "14glun_c"}, {"name": "Glycogen", "notes": {"original_bigg_ids": ["glycogen_c"]}, "charge": 0, "formula": "C6H10O5", "compartment": "c", "id": "glycogen_c"}, {"name": "S aminomethyldihydrolipoamide C9H21N2OS2", "notes": {"original_bigg_ids": ["alpam_m"]}, "charge": 0, "formula": "C9H21N2OS2", "compartment": "m", "id": "alpam_m"}, {"name": "5,10-Methylenetetrahydrofolate", "notes": {"original_bigg_ids": ["mlthf_m"]}, "charge": 0, "formula": "C20H21N7O6", "compartment": "m", "id": "mlthf_m"}, {"name": "Ammonium", "notes": {"original_bigg_ids": ["nh4_m"]}, "charge": 0, "formula": "H4N", "compartment": "m", "id": "nh4_m"}, {"name": "S Aminomethyldihydrolipoylprotein CH6NS2X", "notes": {"original_bigg_ids": ["alpro_m"]}, "charge": 0, "formula": "CH6NS2X", "compartment": "m", "id": "alpro_m"}, {"name": "Lipoylprotein S2X", "notes": {"original_bigg_ids": ["lpro_m"]}, "charge": 0, "formula": "S2X", "compartment": "m", "id": "lpro_m"}, {"name": "Dihydrolipolprotein H2S2X", "notes": {"original_bigg_ids": ["dhlpro_m"]}, "charge": 0, "formula": "H2S2X", "compartment": "m", "id": "dhlpro_m"}, {"name": "Guanosine", "notes": {"original_bigg_ids": ["gsn_c"]}, "charge": 0, "formula": "C10H13N5O5", "compartment": "c", "id": "gsn_c"}, {"name": "Guanine", "notes": {"original_bigg_ids": ["gua_c"]}, "charge": 0, "formula": "C5H5N5O", "compartment": "c", "id": "gua_c"}, {"name": "GDP", "notes": {"original_bigg_ids": ["gdp_n"]}, "charge": 0, "formula": "C10H12N5O11P2", "compartment": "n", "id": "gdp_n"}, {"name": "Galactosylglycerol C9H18O8", "notes": {"original_bigg_ids": ["ggl_c"]}, "charge": 0, "formula": "C9H18O8", "compartment": "c", "id": "ggl_c"}, {"name": "5,10-Methylenetetrahydrofolate", "notes": {"original_bigg_ids": ["mlthf_c"]}, "charge": 0, "formula": "C20H21N7O6", "compartment": "c", "id": "mlthf_c"}, {"name": "L-Serine", "notes": {"original_bigg_ids": ["ser_DASH_L_m"]}, "charge": 0, "formula": "C3H7NO3", "compartment": "m", "id": "ser__L_m"}, {"name": "GMP", "notes": {"original_bigg_ids": ["gmp_c"]}, "charge": 0, "formula": "C10H12N5O8P", "compartment": "c", "id": "gmp_c"}, {"name": "DATP", "notes": {"original_bigg_ids": ["datp_c"]}, "charge": 0, "formula": "C10H12N5O12P3", "compartment": "c", "id": "datp_c"}, {"name": "D-Glucose", "notes": {"original_bigg_ids": ["glc_DASH_D_v"]}, "charge": 0, "formula": "C6H12O6", "compartment": "v", "id": "glc__D_v"}, {"name": "TRNA(Gln)", "notes": {"original_bigg_ids": ["trnagln_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnagln_c"}, {"name": "L-Glutaminyl-tRNA(Gln)", "notes": {"original_bigg_ids": ["glntrna_c"]}, "charge": 0, "formula": "C5H9N2O2R", "compartment": "c", "id": "glntrna_c"}, {"name": "N Tetradecanoylglycylpeptide C18H32N2O4R", "notes": {"original_bigg_ids": ["tglp_c"]}, "charge": 0, "formula": "C18H32N2O4R", "compartment": "c", "id": "tglp_c"}, {"name": "Glycylpeptide C4H7N2O3R", "notes": {"original_bigg_ids": ["glp_c"]}, "charge": 0, "formula": "C4H7N2O3R", "compartment": "c", "id": "glp_c"}, {"name": "Gamma-L-Glutamyl-L-cysteine", "notes": {"original_bigg_ids": ["glucys_c"]}, "charge": 0, "formula": "C8H13N2O5S", "compartment": "c", "id": "glucys_c"}, {"name": "5-Phospho-beta-D-ribosylamine", "notes": {"original_bigg_ids": ["pram_c"]}, "charge": 0, "formula": "C5H11NO7P", "compartment": "c", "id": "pram_c"}, {"name": "L-Glutamyl-tRNA(Glu)", "notes": {"original_bigg_ids": ["glutrna_c"]}, "charge": 0, "formula": "C5H7NO3R", "compartment": "c", "id": "glutrna_c"}, {"name": "TRNA (Glu)", "notes": {"original_bigg_ids": ["trnaglu_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnaglu_c"}, {"name": "L-Glutamyl-tRNA(Glu)", "notes": {"original_bigg_ids": ["glutrna_m"]}, "charge": 0, "formula": "C5H7NO3R", "compartment": "m", "id": "glutrna_m"}, {"name": "TRNA (Glu)", "notes": {"original_bigg_ids": ["trnaglu_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnaglu_m"}, {"name": "Hydroxide ion HO", "notes": {"original_bigg_ids": ["oh1_m"]}, "charge": 0, "formula": "HO", "compartment": "m", "id": "oh1_m"}, {"name": "Hydroxide ion HO", "notes": {"original_bigg_ids": ["oh1_c"]}, "charge": 0, "formula": "HO", "compartment": "c", "id": "oh1_c"}, {"name": "Glyoxylate", "notes": {"original_bigg_ids": ["glx_x"]}, "charge": 0, "formula": "C2H1O3", "compartment": "x", "id": "glx_x"}, {"name": "(R)-S-Lactoylglutathione", "notes": {"original_bigg_ids": ["lgt_DASH_S_c"]}, "charge": 0, "formula": "C13H20N3O8S", "compartment": "c", "id": "lgt__S_c"}, {"name": "Reduced glutathione", "notes": {"original_bigg_ids": ["gthrd_m"]}, "charge": 0, "formula": "C10H16N3O6S", "compartment": "m", "id": "gthrd_m"}, {"name": "(R)-S-Lactoylglutathione", "notes": {"original_bigg_ids": ["lgt_DASH_S_m"]}, "charge": 0, "formula": "C13H20N3O8S", "compartment": "m", "id": "lgt__S_m"}, {"name": "Glycyl-tRNA(Gly)", "notes": {"original_bigg_ids": ["glytrna_c"]}, "charge": 0, "formula": "C2H4NOR", "compartment": "c", "id": "glytrna_c"}, {"name": "TRNA(Gly)", "notes": {"original_bigg_ids": ["trnagly_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnagly_c"}, {"name": "Xanthosine 5'-phosphate", "notes": {"original_bigg_ids": ["xmp_c"]}, "charge": 0, "formula": "C10H11N4O9P", "compartment": "c", "id": "xmp_c"}, {"name": "6-Phospho-D-gluconate", "notes": {"original_bigg_ids": ["6pgc_c"]}, "charge": 0, "formula": "C6H10O10P", "compartment": "c", "id": "6pgc_c"}, {"name": "Farnesyl diphosphate", "notes": {"original_bigg_ids": ["frdp_c"]}, "charge": 0, "formula": "C15H25O7P2", "compartment": "c", "id": "frdp_c"}, {"name": "Guanosine", "notes": {"original_bigg_ids": ["gsn_m"]}, "charge": 0, "formula": "C10H13N5O5", "compartment": "m", "id": "gsn_m"}, {"name": "Oxidized glutathione", "notes": {"original_bigg_ids": ["gthox_c"]}, "charge": 0, "formula": "C20H30N6O12S2", "compartment": "c", "id": "gthox_c"}, {"name": "Cys-Gly", "notes": {"original_bigg_ids": ["cgly_c"]}, "charge": 0, "formula": "C5H10N2O3S", "compartment": "c", "id": "cgly_c"}, {"name": "5 L Glutamyl L alanine C8H13N2O5", "notes": {"original_bigg_ids": ["gluala_c"]}, "charge": 0, "formula": "C8H13N2O5", "compartment": "c", "id": "gluala_c"}, {"name": "Guanine", "notes": {"original_bigg_ids": ["gua_m"]}, "charge": 0, "formula": "C5H5N5O", "compartment": "m", "id": "gua_m"}, {"name": "H2O", "notes": {"original_bigg_ids": ["h2o_r"]}, "charge": 0, "formula": "H2O", "compartment": "r", "id": "h2o_r"}, {"name": "(S)-3-Hydroxyacyl-CoA", "notes": {"original_bigg_ids": ["3hacoa_x"]}, "charge": 0, "formula": "C24H35N7O18P3RS", "compartment": "x", "id": "3hacoa_x"}, {"name": "3-Oxoacyl-CoA", "notes": {"original_bigg_ids": ["3oacoa_x"]}, "charge": 0, "formula": "C24H33N7O18P3RS", "compartment": "x", "id": "3oacoa_x"}, {"name": "But 1 ene 1 2 4 tricarboxylate C7H5O6", "notes": {"original_bigg_ids": ["b124tc_m"]}, "charge": 0, "formula": "C7H5O6", "compartment": "m", "id": "b124tc_m"}, {"name": "Homoisocitrate C7H7O7", "notes": {"original_bigg_ids": ["hicit_m"]}, "charge": 0, "formula": "C7H7O7", "compartment": "m", "id": "hicit_m"}, {"name": "All-trans-Octaprenyl diphosphate (5 repeating units)", "notes": {"original_bigg_ids": ["octdp_5_c"]}, "charge": 0, "formula": "C30H49O7P2", "compartment": "c", "id": "octdp_5_c"}, {"name": "All-trans-Octaprenyl diphosphate (5 repeating units)", "notes": {"original_bigg_ids": ["octdp_5_m"]}, "charge": 0, "formula": "C30H49O7P2", "compartment": "m", "id": "octdp_5_m"}, {"name": "2 Hydroxybutane 1 2 4 tricarboxylate C7H7O7", "notes": {"original_bigg_ids": ["hcit_m"]}, "charge": 0, "formula": "C7H7O7", "compartment": "m", "id": "hcit_m"}, {"name": "Coenzyme A", "notes": {"original_bigg_ids": ["coa_n"]}, "charge": 0, "formula": "C21H32N7O16P3S", "compartment": "n", "id": "coa_n"}, {"name": "Acetyl-CoA", "notes": {"original_bigg_ids": ["accoa_n"]}, "charge": 0, "formula": "C23H34N7O17P3S", "compartment": "n", "id": "accoa_n"}, {"name": "2 Hydroxybutane 1 2 4 tricarboxylate C7H7O7", "notes": {"original_bigg_ids": ["hcit_n"]}, "charge": 0, "formula": "C7H7O7", "compartment": "n", "id": "hcit_n"}, {"name": "Bicarbonate", "notes": {"original_bigg_ids": ["hco3_m"]}, "charge": 0, "formula": "CHO3", "compartment": "m", "id": "hco3_m"}, {"name": "4-Methyl-5-(2-phosphoethyl)-thiazole", "notes": {"original_bigg_ids": ["4mpetz_c"]}, "charge": 0, "formula": "C6H8NO4PS", "compartment": "c", "id": "4mpetz_c"}, {"name": "4-Methyl-5-(2-hydroxyethyl)-thiazole", "notes": {"original_bigg_ids": ["4mhetz_c"]}, "charge": 0, "formula": "C6H9NOS", "compartment": "c", "id": "4mhetz_c"}, {"name": "D-Mannose 6-phosphate", "notes": {"original_bigg_ids": ["man6p_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "man6p_c"}, {"name": "4 Maleylacetoacetate C8H6O6", "notes": {"original_bigg_ids": ["4mlacac_c"]}, "charge": 0, "formula": "C8H6O6", "compartment": "c", "id": "4mlacac_c"}, {"name": "Oxaloglutarate C7H5O7", "notes": {"original_bigg_ids": ["oxag_m"]}, "charge": 0, "formula": "C7H5O7", "compartment": "m", "id": "oxag_m"}, {"name": "L-Histidinol", "notes": {"original_bigg_ids": ["histd_c"]}, "charge": 0, "formula": "C6H12N3O", "compartment": "c", "id": "histd_c"}, {"name": "L-Histidinol phosphate", "notes": {"original_bigg_ids": ["hisp_c"]}, "charge": 0, "formula": "C6H11N3O4P", "compartment": "c", "id": "hisp_c"}, {"name": "TRNA(His)", "notes": {"original_bigg_ids": ["trnahis_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnahis_c"}, {"name": "L-Histidyl-tRNA(His)", "notes": {"original_bigg_ids": ["histrna_c"]}, "charge": 0, "formula": "C6H8N3OR", "compartment": "c", "id": "histrna_c"}, {"name": "TRNA(His)", "notes": {"original_bigg_ids": ["trnahis_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnahis_m"}, {"name": "L-Histidyl-tRNA(His)", "notes": {"original_bigg_ids": ["histrna_m"]}, "charge": 0, "formula": "C6H8N3OR", "compartment": "m", "id": "histrna_m"}, {"name": "L-Histidine", "notes": {"original_bigg_ids": ["his_DASH_L_m"]}, "charge": 0, "formula": "C6H9N3O2", "compartment": "m", "id": "his__L_m"}, {"name": "3 Hydroxy L kynurenine C10H12N2O4", "notes": {"original_bigg_ids": ["hLkynr_c"]}, "charge": 0, "formula": "C10H12N2O4", "compartment": "c", "id": "hLkynr_c"}, {"name": "Hydroxymethylbilane", "notes": {"original_bigg_ids": ["hmbil_c"]}, "charge": 0, "formula": "C40H38N4O17", "compartment": "c", "id": "hmbil_c"}, {"name": "Porphobilinogen", "notes": {"original_bigg_ids": ["ppbng_c"]}, "charge": 0, "formula": "C10H13N2O4", "compartment": "c", "id": "ppbng_c"}, {"name": " R Mevalonate C6H11O4", "notes": {"original_bigg_ids": ["mev_DASH_R_c"]}, "charge": 0, "formula": "C6H11O4", "compartment": "c", "id": "mev__R_c"}, {"name": "Hydroxymethylglutaryl CoA C27H39N7O20P3S", "notes": {"original_bigg_ids": ["hmgcoa_c"]}, "charge": 0, "formula": "C27H39N7O20P3S", "compartment": "c", "id": "hmgcoa_c"}, {"name": "Hydroxymethylglutaryl CoA C27H39N7O20P3S", "notes": {"original_bigg_ids": ["hmgcoa_m"]}, "charge": 0, "formula": "C27H39N7O20P3S", "compartment": "m", "id": "hmgcoa_m"}, {"name": "4-Amino-2-methyl-5-phosphomethylpyrimidine", "notes": {"original_bigg_ids": ["4ampm_c"]}, "charge": 0, "formula": "C6H8N3O4P", "compartment": "c", "id": "4ampm_c"}, {"name": "L 1 Pyrroline 3 hydroxy 5 carboxylate C5H6NO3", "notes": {"original_bigg_ids": ["1p3h5c_c"]}, "charge": 0, "formula": "C5H6NO3", "compartment": "c", "id": "1p3h5c_c"}, {"name": "L 1 Pyrroline 3 hydroxy 5 carboxylate C5H6NO3", "notes": {"original_bigg_ids": ["1p3h5c_m"]}, "charge": 0, "formula": "C5H6NO3", "compartment": "m", "id": "1p3h5c_m"}, {"name": "L-Homoserine", "notes": {"original_bigg_ids": ["hom_DASH_L_c"]}, "charge": 0, "formula": "C4H9NO3", "compartment": "c", "id": "hom__L_c"}, {"name": "O-Phospho-L-homoserine", "notes": {"original_bigg_ids": ["phom_c"]}, "charge": 0, "formula": "C4H8NO6P", "compartment": "c", "id": "phom_c"}, {"name": "3-(Imidazol-4-yl)-2-oxopropyl phosphate", "notes": {"original_bigg_ids": ["imacp_c"]}, "charge": 0, "formula": "C6H7N2O5P", "compartment": "c", "id": "imacp_c"}, {"name": "Pyridoxamine", "notes": {"original_bigg_ids": ["pydam_c"]}, "charge": 0, "formula": "C8H13N2O2", "compartment": "c", "id": "pydam_c"}, {"name": "Pyridoxamine 5'-phosphate", "notes": {"original_bigg_ids": ["pyam5p_c"]}, "charge": 0, "formula": "C8H12N2O5P", "compartment": "c", "id": "pyam5p_c"}, {"name": "5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide", "notes": {"original_bigg_ids": ["prlp_c"]}, "charge": 0, "formula": "C15H21N5O15P2", "compartment": "c", "id": "prlp_c"}, {"name": "D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate", "notes": {"original_bigg_ids": ["eig3p_c"]}, "charge": 0, "formula": "C6H9N2O6P", "compartment": "c", "id": "eig3p_c"}, {"name": "C'-(3-Indolyl)-glycerol 3-phosphate", "notes": {"original_bigg_ids": ["3ig3p_c"]}, "charge": 0, "formula": "C11H12NO6P", "compartment": "c", "id": "3ig3p_c"}, {"name": "1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate", "notes": {"original_bigg_ids": ["2cpr5p_c"]}, "charge": 0, "formula": "C12H13NO9P", "compartment": "c", "id": "2cpr5p_c"}, {"name": "L-Isoleucine", "notes": {"original_bigg_ids": ["ile_DASH_L_c"]}, "charge": 0, "formula": "C6H13NO2", "compartment": "c", "id": "ile__L_c"}, {"name": "L-Isoleucine", "notes": {"original_bigg_ids": ["ile_DASH_L_m"]}, "charge": 0, "formula": "C6H13NO2", "compartment": "m", "id": "ile__L_m"}, {"name": "L-Isoleucyl-tRNA(Ile)", "notes": {"original_bigg_ids": ["iletrna_c"]}, "charge": 0, "formula": "C6H12NOR", "compartment": "c", "id": "iletrna_c"}, {"name": "TRNA(Ile)", "notes": {"original_bigg_ids": ["trnaile_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnaile_c"}, {"name": "TRNA(Ile)", "notes": {"original_bigg_ids": ["trnaile_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnaile_m"}, {"name": "L-Isoleucyl-tRNA(Ile)", "notes": {"original_bigg_ids": ["iletrna_m"]}, "charge": 0, "formula": "C6H12NOR", "compartment": "m", "id": "iletrna_m"}, {"name": "Indolepyruvate C11H8NO3", "notes": {"original_bigg_ids": ["indpyr_c"]}, "charge": 0, "formula": "C11H8NO3", "compartment": "c", "id": "indpyr_c"}, {"name": "Phosphatidyl 1D myo inositol yeast specific C4140H7644O1300P100", "notes": {"original_bigg_ids": ["ptd1ino_SC_c"]}, "charge": 0, "formula": "C4140H7644O1300P100", "compartment": "c", "id": "ptd1ino_SC_c"}, {"name": "Inositol phosphorylceramide ceramide 1 24C yeast specific C4800H9500N100O1100P100", "notes": {"original_bigg_ids": ["ipc124_SC_c"]}, "charge": 0, "formula": "C4800H9500N100O1100P100", "compartment": "c", "id": "ipc124_SC_c"}, {"name": "Inositol phosphorylceramide ceramide 1 26C yeast specific C5000H9900N100O1100P100", "notes": {"original_bigg_ids": ["ipc126_SC_c"]}, "charge": 0, "formula": "C5000H9900N100O1100P100", "compartment": "c", "id": "ipc126_SC_c"}, {"name": "Inositol phosphorylceramide ceramide 2 24C yeast specific C4800H9500N100O1200P100", "notes": {"original_bigg_ids": ["ipc224_SC_c"]}, "charge": 0, "formula": "C4800H9500N100O1200P100", "compartment": "c", "id": "ipc224_SC_c"}, {"name": "Inositol phosphorylceramide ceramide 2 26C yeast specific C5000H9900N100O1200P100", "notes": {"original_bigg_ids": ["ipc226_SC_c"]}, "charge": 0, "formula": "C5000H9900N100O1200P100", "compartment": "c", "id": "ipc226_SC_c"}, {"name": "Inositol phosphorylceramide ceramide 3 24C yeast specific C4800H9500N100O1300P100", "notes": {"original_bigg_ids": ["ipc324_SC_c"]}, "charge": 0, "formula": "C4800H9500N100O1300P100", "compartment": "c", "id": "ipc324_SC_c"}, {"name": "Inositol phosphorylceramide ceramide 3 26C yeast specific C5000H9900N100O1300P100", "notes": {"original_bigg_ids": ["ipc326_SC_c"]}, "charge": 0, "formula": "C5000H9900N100O1300P100", "compartment": "c", "id": "ipc326_SC_c"}, {"name": "3-Carboxy-2-hydroxy-4-methylpentanoate", "notes": {"original_bigg_ids": ["3c2hmp_c"]}, "charge": 0, "formula": "C7H10O5", "compartment": "c", "id": "3c2hmp_c"}, {"name": "2-Isopropylmaleate", "notes": {"original_bigg_ids": ["2ippm_c"]}, "charge": 0, "formula": "C7H8O4", "compartment": "c", "id": "2ippm_c"}, {"name": "Itaconyl CoA C26H35N7O19P3S", "notes": {"original_bigg_ids": ["itaccoa_m"]}, "charge": 0, "formula": "C26H35N7O19P3S", "compartment": "m", "id": "itaccoa_m"}, {"name": "Itaconate C5H4O4", "notes": {"original_bigg_ids": ["itacon_m"]}, "charge": 0, "formula": "C5H4O4", "compartment": "m", "id": "itacon_m"}, {"name": "Acyl-CoA", "notes": {"original_bigg_ids": ["acoa_x"]}, "charge": 0, "formula": "C22H31N7O17P3RS", "compartment": "x", "id": "acoa_x"}, {"name": "Potassium", "notes": {"original_bigg_ids": ["k_c"]}, "charge": 0, "formula": "K", "compartment": "c", "id": "k_c"}, {"name": "L-Lactate", "notes": {"original_bigg_ids": ["lac_DASH_L_m"]}, "charge": 0, "formula": "C3H5O3", "compartment": "m", "id": "lac__L_m"}, {"name": "L-Lactaldehyde", "notes": {"original_bigg_ids": ["lald_DASH_L_m"]}, "charge": 0, "formula": "C3H6O2", "compartment": "m", "id": "lald__L_m"}, {"name": "4-Methyl-2-oxopentanoate", "notes": {"original_bigg_ids": ["4mop_c"]}, "charge": 0, "formula": "C6H9O3", "compartment": "c", "id": "4mop_c"}, {"name": "L-Leucine", "notes": {"original_bigg_ids": ["leu_DASH_L_c"]}, "charge": 0, "formula": "C6H13NO2", "compartment": "c", "id": "leu__L_c"}, {"name": "L-Leucine", "notes": {"original_bigg_ids": ["leu_DASH_L_m"]}, "charge": 0, "formula": "C6H13NO2", "compartment": "m", "id": "leu__L_m"}, {"name": "4-Methyl-2-oxopentanoate", "notes": {"original_bigg_ids": ["4mop_m"]}, "charge": 0, "formula": "C6H9O3", "compartment": "m", "id": "4mop_m"}, {"name": "L-Leucyl-tRNA(Leu)", "notes": {"original_bigg_ids": ["leutrna_c"]}, "charge": 0, "formula": "C6H12NOR", "compartment": "c", "id": "leutrna_c"}, {"name": "TRNA(Leu)", "notes": {"original_bigg_ids": ["trnaleu_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnaleu_c"}, {"name": "L-Leucyl-tRNA(Leu)", "notes": {"original_bigg_ids": ["leutrna_m"]}, "charge": 0, "formula": "C6H12NOR", "compartment": "m", "id": "leutrna_m"}, {"name": "TRNA(Leu)", "notes": {"original_bigg_ids": ["trnaleu_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnaleu_m"}, {"name": "Methylglyoxal", "notes": {"original_bigg_ids": ["mthgxl_c"]}, "charge": 0, "formula": "C3H4O2", "compartment": "c", "id": "mthgxl_c"}, {"name": "Lanosterol C30H50O", "notes": {"original_bigg_ids": ["lanost_c"]}, "charge": 0, "formula": "C30H50O", "compartment": "c", "id": "lanost_c"}, {"name": " S Squalene 2 3 epoxide C30H50O", "notes": {"original_bigg_ids": ["Ssq23epx_c"]}, "charge": 0, "formula": "C30H50O", "compartment": "c", "id": "Ssq23epx_c"}, {"name": "Diacylglycerol pyrophosphate yeast specific C3540H6544O1100P200", "notes": {"original_bigg_ids": ["dagpy_SC_c"]}, "charge": 0, "formula": "C3540H6544O1100P200", "compartment": "c", "id": "dagpy_SC_c"}, {"name": "L-Lysine", "notes": {"original_bigg_ids": ["lys_DASH_L_c"]}, "charge": 0, "formula": "C6H15N2O2", "compartment": "c", "id": "lys__L_c"}, {"name": "TRNA(Lys)", "notes": {"original_bigg_ids": ["trnalys_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnalys_c"}, {"name": "L-Lysine-tRNA (Lys)", "notes": {"original_bigg_ids": ["lystrna_c"]}, "charge": 0, "formula": "C6H14N2OR", "compartment": "c", "id": "lystrna_c"}, {"name": "L-Lysine", "notes": {"original_bigg_ids": ["lys_DASH_L_m"]}, "charge": 0, "formula": "C6H15N2O2", "compartment": "m", "id": "lys__L_m"}, {"name": "L-Lysine-tRNA (Lys)", "notes": {"original_bigg_ids": ["lystrna_m"]}, "charge": 0, "formula": "C6H14N2OR", "compartment": "m", "id": "lystrna_m"}, {"name": "TRNA(Lys)", "notes": {"original_bigg_ids": ["trnalys_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnalys_m"}, {"name": "L-Lactate", "notes": {"original_bigg_ids": ["lac_DASH_L_c"]}, "charge": 0, "formula": "C3H5O3", "compartment": "c", "id": "lac__L_c"}, {"name": "D-Mannitol 1-phosphate", "notes": {"original_bigg_ids": ["mnl1p_c"]}, "charge": 0, "formula": "C6H13O9P", "compartment": "c", "id": "mnl1p_c"}, {"name": "Maltose", "notes": {"original_bigg_ids": ["malt_c"]}, "charge": 0, "formula": "C12H22O11", "compartment": "c", "id": "malt_c"}, {"name": "D-Mannose 1-phosphate", "notes": {"original_bigg_ids": ["man1p_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "man1p_c"}, {"name": "Mannan C6H10O5", "notes": {"original_bigg_ids": ["mannan_c"]}, "charge": 0, "formula": "C6H10O5", "compartment": "c", "id": "mannan_c"}, {"name": "Propanoyl-CoA", "notes": {"original_bigg_ids": ["ppcoa_c"]}, "charge": 0, "formula": "C24H36N7O17P3S", "compartment": "c", "id": "ppcoa_c"}, {"name": "Malonyl-[acyl-carrier protein]", "notes": {"original_bigg_ids": ["malACP_c"]}, "charge": 0, "formula": "C14H22N2O10PRS", "compartment": "c", "id": "malACP_c"}, {"name": "Malonyl-CoA", "notes": {"original_bigg_ids": ["malcoa_m"]}, "charge": 0, "formula": "C24H33N7O19P3S", "compartment": "m", "id": "malcoa_m"}, {"name": "D-Sorbitol", "notes": {"original_bigg_ids": ["sbt_DASH_D_c"]}, "charge": 0, "formula": "C6H14O6", "compartment": "c", "id": "sbt__D_c"}, {"name": "Melibiitol C12H24O11", "notes": {"original_bigg_ids": ["melt_c"]}, "charge": 0, "formula": "C12H24O11", "compartment": "c", "id": "melt_c"}, {"name": "L-Methionyl-tRNA (Met)", "notes": {"original_bigg_ids": ["mettrna_c"]}, "charge": 0, "formula": "C5H10NOSR", "compartment": "c", "id": "mettrna_c"}, {"name": "TRNA(Met)", "notes": {"original_bigg_ids": ["trnamet_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnamet_c"}, {"name": "TRNA(Met)", "notes": {"original_bigg_ids": ["trnamet_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnamet_m"}, {"name": "L-Methionine", "notes": {"original_bigg_ids": ["met_DASH_L_m"]}, "charge": 0, "formula": "C5H11NO2S", "compartment": "m", "id": "met__L_m"}, {"name": " R 5 Phosphomevalonate C6H10O7P", "notes": {"original_bigg_ids": ["5pmev_c"]}, "charge": 0, "formula": "C6H10O7P", "compartment": "c", "id": "5pmev_c"}, {"name": "Phosphatidyl N methylethanolamine yeast specific C3840H7444N100O800P100", "notes": {"original_bigg_ids": ["ptdmeeta_SC_c"]}, "charge": 0, "formula": "C3840H7444N100O800P100", "compartment": "c", "id": "ptdmeeta_SC_c"}, {"name": "Phosphatidyl N dimethylethanolamine C3940H7644N100O800P100", "notes": {"original_bigg_ids": ["ptd2meeta_SC_c"]}, "charge": 0, "formula": "C3940H7644N100O800P100", "compartment": "c", "id": "ptd2meeta_SC_c"}, {"name": "Tetrahydropteroyltri L glutamate C24H34N8O12", "notes": {"original_bigg_ids": ["hpglu_c"]}, "charge": 0, "formula": "C24H34N8O12", "compartment": "c", "id": "hpglu_c"}, {"name": "5 Methyltetrahydropteroyltri L glutamate C25H36N8O12", "notes": {"original_bigg_ids": ["mhpglu_c"]}, "charge": 0, "formula": "C25H36N8O12", "compartment": "c", "id": "mhpglu_c"}, {"name": "1D-myo-Inositol 1-phosphate", "notes": {"original_bigg_ids": ["mi1p_DASH_D_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "mi1p__D_c"}, {"name": "Mannose inositol P 2 ceramide ceramide 1 24C yeast specific C6000H11500N100O2400P200", "notes": {"original_bigg_ids": ["mip2c124_SC_c"]}, "charge": 0, "formula": "C6000H11500N100O2400P200", "compartment": "c", "id": "mip2c124_SC_c"}, {"name": "Mannose inositol phosphorylceramide ceramide 1 24C yeast specific C5400H10500N100O1600P100", "notes": {"original_bigg_ids": ["mipc124_SC_c"]}, "charge": 0, "formula": "C5400H10500N100O1600P100", "compartment": "c", "id": "mipc124_SC_c"}, {"name": "Mannose inositol phosphorylceramide ceramide 1 26C yeast specific C5600H10900N100O1600P100", "notes": {"original_bigg_ids": ["mipc126_SC_c"]}, "charge": 0, "formula": "C5600H10900N100O1600P100", "compartment": "c", "id": "mipc126_SC_c"}, {"name": "Mannose inositol P 2 ceramide ceramide 1 26C yeast specific C6200H11900N100O2400P200", "notes": {"original_bigg_ids": ["mip2c126_SC_c"]}, "charge": 0, "formula": "C6200H11900N100O2400P200", "compartment": "c", "id": "mip2c126_SC_c"}, {"name": "Mannose inositol phosphorylceramide ceramide 2 24C yeast specific C5400H10500N100O1700P100", "notes": {"original_bigg_ids": ["mipc224_SC_c"]}, "charge": 0, "formula": "C5400H10500N100O1700P100", "compartment": "c", "id": "mipc224_SC_c"}, {"name": "Mannose inositol P 2 ceramide ceramide 2 24C yeast specific C6000H11500N100O2500P200", "notes": {"original_bigg_ids": ["mip2c224_SC_c"]}, "charge": 0, "formula": "C6000H11500N100O2500P200", "compartment": "c", "id": "mip2c224_SC_c"}, {"name": "Mannose inositol phosphorylceramide ceramide 2 26C yeast specific C5600H10900N100O1700P100", "notes": {"original_bigg_ids": ["mipc226_SC_c"]}, "charge": 0, "formula": "C5600H10900N100O1700P100", "compartment": "c", "id": "mipc226_SC_c"}, {"name": "Mannose inositol P 2 ceramide ceramide 2 26C yeast specific C6200H11900N100O2500P200", "notes": {"original_bigg_ids": ["mip2c226_SC_c"]}, "charge": 0, "formula": "C6200H11900N100O2500P200", "compartment": "c", "id": "mip2c226_SC_c"}, {"name": "Mannose inositol P 2 ceramide ceramide 3 24C yeast specific C6000H11500N100O2600P200", "notes": {"original_bigg_ids": ["mip2c324_SC_c"]}, "charge": 0, "formula": "C6000H11500N100O2600P200", "compartment": "c", "id": "mip2c324_SC_c"}, {"name": "Mannose inositol phosphorylceramide ceramide 3 24C yeast specific C5400H10500N100O1800P100", "notes": {"original_bigg_ids": ["mipc324_SC_c"]}, "charge": 0, "formula": "C5400H10500N100O1800P100", "compartment": "c", "id": "mipc324_SC_c"}, {"name": "Mannose inositol phosphorylceramide ceramide 3 26C C5600H10900N100O1800P100", "notes": {"original_bigg_ids": ["mipc326_SC_c"]}, "charge": 0, "formula": "C5600H10900N100O1800P100", "compartment": "c", "id": "mipc326_SC_c"}, {"name": "Mannose inositol P 2 ceramide ceramide 3 26C yeast specific C6200H11900N100O2600P200", "notes": {"original_bigg_ids": ["mip2c326_SC_c"]}, "charge": 0, "formula": "C6200H11900N100O2600P200", "compartment": "c", "id": "mip2c326_SC_c"}, {"name": "S-Methyl-L-methionine", "notes": {"original_bigg_ids": ["mmet_c"]}, "charge": 0, "formula": "C6H14NO2S", "compartment": "c", "id": "mmet_c"}, {"name": "NMN", "notes": {"original_bigg_ids": ["nmn_x"]}, "charge": 0, "formula": "C11H14N2O8P", "compartment": "x", "id": "nmn_x"}, {"name": "Nicotinamide", "notes": {"original_bigg_ids": ["ncam_c"]}, "charge": 0, "formula": "C6H6N2O", "compartment": "c", "id": "ncam_c"}, {"name": "ADPribose", "notes": {"original_bigg_ids": ["adprib_c"]}, "charge": 0, "formula": "C15H21N5O14P2", "compartment": "c", "id": "adprib_c"}, {"name": "Nicotinamide", "notes": {"original_bigg_ids": ["ncam_m"]}, "charge": 0, "formula": "C6H6N2O", "compartment": "m", "id": "ncam_m"}, {"name": "ADPribose", "notes": {"original_bigg_ids": ["adprib_m"]}, "charge": 0, "formula": "C15H21N5O14P2", "compartment": "m", "id": "adprib_m"}, {"name": "Deamino-NAD+", "notes": {"original_bigg_ids": ["dnad_c"]}, "charge": 0, "formula": "C21H24N6O15P2", "compartment": "c", "id": "dnad_c"}, {"name": "Deamino-NAD+", "notes": {"original_bigg_ids": ["dnad_m"]}, "charge": 0, "formula": "C21H24N6O15P2", "compartment": "m", "id": "dnad_m"}, {"name": "Nicotinate", "notes": {"original_bigg_ids": ["nac_c"]}, "charge": 0, "formula": "C6H4NO2", "compartment": "c", "id": "nac_c"}, {"name": "Nicotinate D-ribonucleotide", "notes": {"original_bigg_ids": ["nicrnt_c"]}, "charge": 0, "formula": "C11H12NO9P", "compartment": "c", "id": "nicrnt_c"}, {"name": "Nicotinate", "notes": {"original_bigg_ids": ["nac_m"]}, "charge": 0, "formula": "C6H4NO2", "compartment": "m", "id": "nac_m"}, {"name": "Nicotinate D-ribonucleotide", "notes": {"original_bigg_ids": ["nicrnt_m"]}, "charge": 0, "formula": "C11H12NO9P", "compartment": "m", "id": "nicrnt_m"}, {"name": "5-Phospho-alpha-D-ribose 1-diphosphate", "notes": {"original_bigg_ids": ["prpp_m"]}, "charge": 0, "formula": "C5H8O14P3", "compartment": "m", "id": "prpp_m"}, {"name": "Sodium", "notes": {"original_bigg_ids": ["na1_c"]}, "charge": 0, "formula": "Na", "compartment": "c", "id": "na1_c"}, {"name": "GMP", "notes": {"original_bigg_ids": ["gmp_g"]}, "charge": 0, "formula": "C10H12N5O8P", "compartment": "g", "id": "gmp_g"}, {"name": "DGTP", "notes": {"original_bigg_ids": ["dgtp_c"]}, "charge": 0, "formula": "C10H12N5O13P3", "compartment": "c", "id": "dgtp_c"}, {"name": "DUDP", "notes": {"original_bigg_ids": ["dudp_c"]}, "charge": 0, "formula": "C9H11N2O11P2", "compartment": "c", "id": "dudp_c"}, {"name": "NMN", "notes": {"original_bigg_ids": ["nmn_c"]}, "charge": 0, "formula": "C11H14N2O8P", "compartment": "c", "id": "nmn_c"}, {"name": "NMN", "notes": {"original_bigg_ids": ["nmn_m"]}, "charge": 0, "formula": "C11H14N2O8P", "compartment": "m", "id": "nmn_m"}, {"name": "Quinolinate", "notes": {"original_bigg_ids": ["quln_c"]}, "charge": 0, "formula": "C7H3NO4", "compartment": "c", "id": "quln_c"}, {"name": "Quinolinate", "notes": {"original_bigg_ids": ["quln_m"]}, "charge": 0, "formula": "C7H3NO4", "compartment": "m", "id": "quln_m"}, {"name": "Xanthosine", "notes": {"original_bigg_ids": ["xtsn_c"]}, "charge": 0, "formula": "C10H12N4O6", "compartment": "c", "id": "xtsn_c"}, {"name": "UMP", "notes": {"original_bigg_ids": ["ump_c"]}, "charge": 0, "formula": "C9H11N2O9P", "compartment": "c", "id": "ump_c"}, {"name": "Thymidine", "notes": {"original_bigg_ids": ["thymd_c"]}, "charge": 0, "formula": "C10H14N2O5", "compartment": "c", "id": "thymd_c"}, {"name": "Indole 3 acetonitrile C10H8N2", "notes": {"original_bigg_ids": ["ind3acnl_c"]}, "charge": 0, "formula": "C10H8N2", "compartment": "c", "id": "ind3acnl_c"}, {"name": "Alpha Aminopropiononitrile C3H7N2", "notes": {"original_bigg_ids": ["aprop_c"]}, "charge": 0, "formula": "C3H7N2", "compartment": "c", "id": "aprop_c"}, {"name": "Gamma Amino gamma cyanobutanoate C5H8N2O2", "notes": {"original_bigg_ids": ["acybut_c"]}, "charge": 0, "formula": "C5H8N2O2", "compartment": "c", "id": "acybut_c"}, {"name": "O2", "notes": {"original_bigg_ids": ["o2_r"]}, "charge": 0, "formula": "O2", "compartment": "r", "id": "o2_r"}, {"name": "2-Oxo-3-hydroxy-4-phosphobutanoate", "notes": {"original_bigg_ids": ["ohpb_c"]}, "charge": 0, "formula": "C4H4O8P", "compartment": "c", "id": "ohpb_c"}, {"name": "2-Octaprenyl-6-methoxy-1,4-benzoquinol (5 repeating units)", "notes": {"original_bigg_ids": ["2ombzl_5_m"]}, "charge": 0, "formula": "C37H56O3", "compartment": "m", "id": "2ombzl_5_m"}, {"name": "2-Octaprenyl3-methyl-6-methoxy-1,4-benzoquinol (5 repeating units)", "notes": {"original_bigg_ids": ["2ommbl_5_m"]}, "charge": 0, "formula": "C38H58O3", "compartment": "m", "id": "2ommbl_5_m"}, {"name": "Orotidine 5'-phosphate", "notes": {"original_bigg_ids": ["orot5p_c"]}, "charge": 0, "formula": "C10H10N2O11P", "compartment": "c", "id": "orot5p_c"}, {"name": "2-Octaprenylphenol (5 repeating units)", "notes": {"original_bigg_ids": ["2oph_5_c"]}, "charge": 0, "formula": "C36H54O", "compartment": "c", "id": "2oph_5_c"}, {"name": "Putrescine", "notes": {"original_bigg_ids": ["ptrc_c"]}, "charge": 0, "formula": "C4H14N2", "compartment": "c", "id": "ptrc_c"}, {"name": "Ornithine", "notes": {"original_bigg_ids": ["orn_m"]}, "charge": 0, "formula": "C5H13N2O2", "compartment": "m", "id": "orn_m"}, {"name": "Oxaloglutarate C7H5O7", "notes": {"original_bigg_ids": ["oxag_c"]}, "charge": 0, "formula": "C7H5O7", "compartment": "c", "id": "oxag_c"}, {"name": "L-Proline", "notes": {"original_bigg_ids": ["pro_DASH_L_c"]}, "charge": 0, "formula": "C5H9NO2", "compartment": "c", "id": "pro__L_c"}, {"name": "Pantetheine 4'-phosphate", "notes": {"original_bigg_ids": ["pan4p_c"]}, "charge": 0, "formula": "C11H21N2O7PS", "compartment": "c", "id": "pan4p_c"}, {"name": "(R)-Pantothenate", "notes": {"original_bigg_ids": ["pnto_DASH_R_c"]}, "charge": 0, "formula": "C9H16NO5", "compartment": "c", "id": "pnto__R_c"}, {"name": "Reduced thioredoxin", "notes": {"original_bigg_ids": ["trdrd_c"]}, "charge": 0, "formula": "XH2", "compartment": "c", "id": "trdrd_c"}, {"name": "Oxidized thioredoxin", "notes": {"original_bigg_ids": ["trdox_c"]}, "charge": 0, "formula": "X", "compartment": "c", "id": "trdox_c"}, {"name": "Sulfite", "notes": {"original_bigg_ids": ["so3_c"]}, "charge": 0, "formula": "O3S", "compartment": "c", "id": "so3_c"}, {"name": "3 5 Cyclic dAMP C10H11N5O5P", "notes": {"original_bigg_ids": ["35cdamp_c"]}, "charge": 0, "formula": "C10H11N5O5P", "compartment": "c", "id": "35cdamp_c"}, {"name": "3 5 Cyclic IMP C10H10N4O7P", "notes": {"original_bigg_ids": ["35cimp_c"]}, "charge": 0, "formula": "C10H10N4O7P", "compartment": "c", "id": "35cimp_c"}, {"name": "3',5'-Cyclic GMP", "notes": {"original_bigg_ids": ["35cgmp_c"]}, "charge": 0, "formula": "C10H11N5O7P", "compartment": "c", "id": "35cgmp_c"}, {"name": "3 5 Cyclic CMP C9H11N3O7P", "notes": {"original_bigg_ids": ["35ccmp_c"]}, "charge": 0, "formula": "C9H11N3O7P", "compartment": "c", "id": "35ccmp_c"}, {"name": "Pyridoxine 5'-phosphate", "notes": {"original_bigg_ids": ["pdx5p_c"]}, "charge": 0, "formula": "C8H10NO6P", "compartment": "c", "id": "pdx5p_c"}, {"name": "Pyridoxal 5'-phosphate", "notes": {"original_bigg_ids": ["pydx5p_c"]}, "charge": 0, "formula": "C8H8NO6P", "compartment": "c", "id": "pydx5p_c"}, {"name": "Peptide C2H4NO2RC2H2NOR", "notes": {"original_bigg_ids": ["pepd_c"]}, "charge": 0, "formula": "C2H4NO2RC2H2NOR", "compartment": "c", "id": "pepd_c"}, {"name": "Nalpha Acetylpeptide C6H7N2O4R2", "notes": {"original_bigg_ids": ["apep_c"]}, "charge": 0, "formula": "C6H7N2O4R2", "compartment": "c", "id": "apep_c"}, {"name": "Phosphatidylethanolamine yeast specific C3740H7244N100O800P100", "notes": {"original_bigg_ids": ["pe_SC_g"]}, "charge": 0, "formula": "C3740H7244N100O800P100", "compartment": "g", "id": "pe_SC_g"}, {"name": "Phosphatidylethanolamine yeast specific C3740H7244N100O800P100", "notes": {"original_bigg_ids": ["pe_SC_m"]}, "charge": 0, "formula": "C3740H7244N100O800P100", "compartment": "m", "id": "pe_SC_m"}, {"name": "Phosphatidylethanolamine yeast specific C3740H7244N100O800P100", "notes": {"original_bigg_ids": ["pe_SC_v"]}, "charge": 0, "formula": "C3740H7244N100O800P100", "compartment": "v", "id": "pe_SC_v"}, {"name": "D-Tagatose 6-phosphate", "notes": {"original_bigg_ids": ["tag6p_DASH_D_c"]}, "charge": 0, "formula": "C6H11O9P", "compartment": "c", "id": "tag6p__D_c"}, {"name": "D-Tagatose 1,6-biphosphate", "notes": {"original_bigg_ids": ["tagdp_DASH_D_c"]}, "charge": 0, "formula": "C6H10O12P2", "compartment": "c", "id": "tagdp__D_c"}, {"name": "Sedoheptulose 7-phosphate", "notes": {"original_bigg_ids": ["s7p_c"]}, "charge": 0, "formula": "C7H13O10P", "compartment": "c", "id": "s7p_c"}, {"name": "D-Glucosamine 1-phosphate", "notes": {"original_bigg_ids": ["gam1p_c"]}, "charge": 0, "formula": "C6H13NO8P", "compartment": "c", "id": "gam1p_c"}, {"name": "3-Phospho-D-glycerate", "notes": {"original_bigg_ids": ["3pg_c"]}, "charge": 0, "formula": "C3H4O7P", "compartment": "c", "id": "3pg_c"}, {"name": "3-Phosphohydroxypyruvate", "notes": {"original_bigg_ids": ["3php_c"]}, "charge": 0, "formula": "C3H2O7P", "compartment": "c", "id": "3php_c"}, {"name": "Phenylpyruvate", "notes": {"original_bigg_ids": ["phpyr_c"]}, "charge": 0, "formula": "C9H7O3", "compartment": "c", "id": "phpyr_c"}, {"name": "L-Phenylalanine", "notes": {"original_bigg_ids": ["phe_DASH_L_c"]}, "charge": 0, "formula": "C9H11NO2", "compartment": "c", "id": "phe__L_c"}, {"name": "L-Phenylalanyl-tRNA(Phe)", "notes": {"original_bigg_ids": ["phetrna_c"]}, "charge": 0, "formula": "C9H10NOR", "compartment": "c", "id": "phetrna_c"}, {"name": "TRNA(Phe)", "notes": {"original_bigg_ids": ["trnaphe_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnaphe_c"}, {"name": "L-Phenylalanyl-tRNA(Phe)", "notes": {"original_bigg_ids": ["phetrna_m"]}, "charge": 0, "formula": "C9H10NOR", "compartment": "m", "id": "phetrna_m"}, {"name": "TRNA(Phe)", "notes": {"original_bigg_ids": ["trnaphe_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnaphe_m"}, {"name": "L-Phenylalanine", "notes": {"original_bigg_ids": ["phe_DASH_L_m"]}, "charge": 0, "formula": "C9H11NO2", "compartment": "m", "id": "phe__L_m"}, {"name": "Phosphatidyl 1D myo 3 inositol yeast specific C4140H7544O1600P200", "notes": {"original_bigg_ids": ["ptd3ino_SC_c"]}, "charge": 0, "formula": "C4140H7544O1600P200", "compartment": "c", "id": "ptd3ino_SC_c"}, {"name": "Phosphatidyl 1D myo inositol 3 4 bisphosphate yeast specific C4140H7444O1900P300", "notes": {"original_bigg_ids": ["ptd134bp_SC_c"]}, "charge": 0, "formula": "C4140H7444O1900P300", "compartment": "c", "id": "ptd134bp_SC_c"}, {"name": "1 Phosphatidyl D myo inositol 4 5 bisphosphate yeast specific C4140H7444O1900P300", "notes": {"original_bigg_ids": ["ptd145bp_SC_c"]}, "charge": 0, "formula": "C4140H7444O1900P300", "compartment": "c", "id": "ptd145bp_SC_c"}, {"name": "1D myo Inositol 1 4 5 trisphosphate C6H9O15P3", "notes": {"original_bigg_ids": ["mi145p_c"]}, "charge": 0, "formula": "C6H9O15P3", "compartment": "c", "id": "mi145p_c"}, {"name": "Phosphatidyl 1D myo 4 inositol yeast specific C4140H7544O1600P200", "notes": {"original_bigg_ids": ["ptd4ino_SC_c"]}, "charge": 0, "formula": "C4140H7544O1600P200", "compartment": "c", "id": "ptd4ino_SC_c"}, {"name": "Phosphatidyl 1D myo inositol yeast specific C4140H7644O1300P100", "notes": {"original_bigg_ids": ["ptd1ino_SC_n"]}, "charge": 0, "formula": "C4140H7644O1300P100", "compartment": "n", "id": "ptd1ino_SC_n"}, {"name": "Phosphatidyl 1D myo 4 inositol yeast specific C4140H7544O1600P200", "notes": {"original_bigg_ids": ["ptd4ino_SC_n"]}, "charge": 0, "formula": "C4140H7544O1600P200", "compartment": "n", "id": "ptd4ino_SC_n"}, {"name": "4-(1-D-Ribitylamino)-5-aminouracil", "notes": {"original_bigg_ids": ["4r5au_c"]}, "charge": 0, "formula": "C9H16N4O6", "compartment": "c", "id": "4r5au_c"}, {"name": "2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate", "notes": {"original_bigg_ids": ["2mahmp_c"]}, "charge": 0, "formula": "C6H8N3O7P2", "compartment": "c", "id": "2mahmp_c"}, {"name": "D-4'-Phosphopantothenate", "notes": {"original_bigg_ids": ["4ppan_c"]}, "charge": 0, "formula": "C9H15NO8P", "compartment": "c", "id": "4ppan_c"}, {"name": "N1-Acetylspermidine", "notes": {"original_bigg_ids": ["N1aspmd_c"]}, "charge": 0, "formula": "C9H23N3O", "compartment": "c", "id": "N1aspmd_c"}, {"name": "3 Aminopropanal C3H8NO", "notes": {"original_bigg_ids": ["aproa_c"]}, "charge": 0, "formula": "C3H8NO", "compartment": "c", "id": "aproa_c"}, {"name": "N-((R)-4-Phosphopantothenoyl)-L-cysteine", "notes": {"original_bigg_ids": ["4ppcys_c"]}, "charge": 0, "formula": "C12H20N2O9PS", "compartment": "c", "id": "4ppcys_c"}, {"name": "Alpha-D-Ribose 1-phosphate", "notes": {"original_bigg_ids": ["r1p_c"]}, "charge": 0, "formula": "C5H9O8P", "compartment": "c", "id": "r1p_c"}, {"name": "Protoporphyrinogen IX", "notes": {"original_bigg_ids": ["pppg9_m"]}, "charge": 0, "formula": "C34H38N4O4", "compartment": "m", "id": "pppg9_m"}, {"name": "2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine", "notes": {"original_bigg_ids": ["fpram_c"]}, "charge": 0, "formula": "C8H15N3O8P", "compartment": "c", "id": "fpram_c"}, {"name": "1-(5-Phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide", "notes": {"original_bigg_ids": ["prfp_c"]}, "charge": 0, "formula": "C15H21N5O15P2", "compartment": "c", "id": "prfp_c"}, {"name": "1-(5-Phosphoribosyl)-AMP", "notes": {"original_bigg_ids": ["prbamp_c"]}, "charge": 0, "formula": "C15H19N5O14P2", "compartment": "c", "id": "prbamp_c"}, {"name": "L-Proline", "notes": {"original_bigg_ids": ["pro_DASH_L_m"]}, "charge": 0, "formula": "C5H9NO2", "compartment": "m", "id": "pro__L_m"}, {"name": "TRNA(Pro)", "notes": {"original_bigg_ids": ["trnapro_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnapro_c"}, {"name": "L-Prolyl-tRNA(Pro)", "notes": {"original_bigg_ids": ["protrna_c"]}, "charge": 0, "formula": "C5H8NOR", "compartment": "c", "id": "protrna_c"}, {"name": "Shikimate 5-phosphate", "notes": {"original_bigg_ids": ["skm5p_c"]}, "charge": 0, "formula": "C7H8O8P", "compartment": "c", "id": "skm5p_c"}, {"name": "Phosphatidylserine yeast specific C3840H7144N100O1000P100", "notes": {"original_bigg_ids": ["ps_SC_g"]}, "charge": 0, "formula": "C3840H7144N100O1000P100", "compartment": "g", "id": "ps_SC_g"}, {"name": "Phosphatidylserine yeast specific C3840H7144N100O1000P100", "notes": {"original_bigg_ids": ["ps_SC_m"]}, "charge": 0, "formula": "C3840H7144N100O1000P100", "compartment": "m", "id": "ps_SC_m"}, {"name": "Phosphatidylserine yeast specific C3840H7144N100O1000P100", "notes": {"original_bigg_ids": ["ps_SC_v"]}, "charge": 0, "formula": "C3840H7144N100O1000P100", "compartment": "v", "id": "ps_SC_v"}, {"name": "Phosphatidylserine yeast specific C3840H7144N100O1000P100", "notes": {"original_bigg_ids": ["ps_SC_c"]}, "charge": 0, "formula": "C3840H7144N100O1000P100", "compartment": "c", "id": "ps_SC_c"}, {"name": "O-Phospho-L-serine", "notes": {"original_bigg_ids": ["pser_DASH_L_c"]}, "charge": 0, "formula": "C3H6NO6P", "compartment": "c", "id": "pser__L_c"}, {"name": "Phytosphingosine 1 phosphate C18H39NO6P", "notes": {"original_bigg_ids": ["psph1p_c"]}, "charge": 0, "formula": "C18H39NO6P", "compartment": "c", "id": "psph1p_c"}, {"name": "2 Hydroxy hexadecanal C16H32O2", "notes": {"original_bigg_ids": ["2hhxdal_c"]}, "charge": 0, "formula": "C16H32O2", "compartment": "c", "id": "2hhxdal_c"}, {"name": "Adenosine", "notes": {"original_bigg_ids": ["adn_m"]}, "charge": 0, "formula": "C10H13N5O4", "compartment": "m", "id": "adn_m"}, {"name": "Alpha-D-Ribose 1-phosphate", "notes": {"original_bigg_ids": ["r1p_m"]}, "charge": 0, "formula": "C5H9O8P", "compartment": "m", "id": "r1p_m"}, {"name": "Xanthine", "notes": {"original_bigg_ids": ["xan_c"]}, "charge": 0, "formula": "C5H4N4O2", "compartment": "c", "id": "xan_c"}, {"name": "Pyridoxal", "notes": {"original_bigg_ids": ["pydx_c"]}, "charge": 0, "formula": "C8H9NO3", "compartment": "c", "id": "pydx_c"}, {"name": "Pyridoxine", "notes": {"original_bigg_ids": ["pydxn_c"]}, "charge": 0, "formula": "C8H11NO3", "compartment": "c", "id": "pydxn_c"}, {"name": "Raffinose C18H32O16", "notes": {"original_bigg_ids": ["raffin_c"]}, "charge": 0, "formula": "C18H32O16", "compartment": "c", "id": "raffin_c"}, {"name": "Sucrose", "notes": {"original_bigg_ids": ["sucr_c"]}, "charge": 0, "formula": "C12H22O11", "compartment": "c", "id": "sucr_c"}, {"name": "Riboflavin", "notes": {"original_bigg_ids": ["ribflv_c"]}, "charge": 0, "formula": "C17H20N4O6", "compartment": "c", "id": "ribflv_c"}, {"name": "Riboflavin", "notes": {"original_bigg_ids": ["ribflv_m"]}, "charge": 0, "formula": "C17H20N4O6", "compartment": "m", "id": "ribflv_m"}, {"name": "6,7-Dimethyl-8-(1-D-ribityl)lumazine", "notes": {"original_bigg_ids": ["dmlz_c"]}, "charge": 0, "formula": "C13H18N4O6", "compartment": "c", "id": "dmlz_c"}, {"name": "Reduced thioredoxin", "notes": {"original_bigg_ids": ["trdrd_n"]}, "charge": 0, "formula": "XH2", "compartment": "n", "id": "trdrd_n"}, {"name": "Oxidized thioredoxin", "notes": {"original_bigg_ids": ["trdox_n"]}, "charge": 0, "formula": "X", "compartment": "n", "id": "trdox_n"}, {"name": "DUDP", "notes": {"original_bigg_ids": ["dudp_n"]}, "charge": 0, "formula": "C9H11N2O11P2", "compartment": "n", "id": "dudp_n"}, {"name": "UDP", "notes": {"original_bigg_ids": ["udp_n"]}, "charge": 0, "formula": "C9H11N2O12P2", "compartment": "n", "id": "udp_n"}, {"name": "D-Xylulose 5-phosphate", "notes": {"original_bigg_ids": ["xu5p_DASH_D_c"]}, "charge": 0, "formula": "C5H9O8P", "compartment": "c", "id": "xu5p__D_c"}, {"name": "L Saccharopine C11H19N2O6", "notes": {"original_bigg_ids": ["saccrp_DASH_L_c"]}, "charge": 0, "formula": "C11H19N2O6", "compartment": "c", "id": "saccrp__L_c"}, {"name": "Sulfate", "notes": {"original_bigg_ids": ["so4_c"]}, "charge": 0, "formula": "O4S", "compartment": "c", "id": "so4_c"}, {"name": "Sphinganine 1 phosphate C18H39NO5P", "notes": {"original_bigg_ids": ["sph1p_c"]}, "charge": 0, "formula": "C18H39NO5P", "compartment": "c", "id": "sph1p_c"}, {"name": "L Sorbose C6H12O6", "notes": {"original_bigg_ids": ["srb_DASH_L_c"]}, "charge": 0, "formula": "C6H12O6", "compartment": "c", "id": "srb__L_c"}, {"name": "L Sorbitol C6H14O6", "notes": {"original_bigg_ids": ["sbt_DASH_L_c"]}, "charge": 0, "formula": "C6H14O6", "compartment": "c", "id": "sbt__L_c"}, {"name": "TRNA(Ser)", "notes": {"original_bigg_ids": ["trnaser_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnaser_c"}, {"name": "L-Seryl-tRNA(Ser)", "notes": {"original_bigg_ids": ["sertrna_c"]}, "charge": 0, "formula": "C3H6NO2R", "compartment": "c", "id": "sertrna_c"}, {"name": "Shikimate", "notes": {"original_bigg_ids": ["skm_c"]}, "charge": 0, "formula": "C7H9O5", "compartment": "c", "id": "skm_c"}, {"name": "O-Succinyl-L-homoserine", "notes": {"original_bigg_ids": ["suchms_c"]}, "charge": 0, "formula": "C8H12NO6", "compartment": "c", "id": "suchms_c"}, {"name": "Hexadecanal C16H32O", "notes": {"original_bigg_ids": ["hxdcal_c"]}, "charge": 0, "formula": "C16H32O", "compartment": "c", "id": "hxdcal_c"}, {"name": "5-Methylthioadenosine", "notes": {"original_bigg_ids": ["5mta_c"]}, "charge": 0, "formula": "C11H15N5O3S", "compartment": "c", "id": "5mta_c"}, {"name": " S Squalene 2 3 epoxide C30H50O", "notes": {"original_bigg_ids": ["Ssq23epx_r"]}, "charge": 0, "formula": "C30H50O", "compartment": "r", "id": "Ssq23epx_r"}, {"name": "Squalene C30H50", "notes": {"original_bigg_ids": ["sql_r"]}, "charge": 0, "formula": "C30H50", "compartment": "r", "id": "sql_r"}, {"name": "Squalene C30H50", "notes": {"original_bigg_ids": ["sql_c"]}, "charge": 0, "formula": "C30H50", "compartment": "c", "id": "sql_c"}, {"name": "Tetrahydrofolyl Glu 2 C24H27N8O9", "notes": {"original_bigg_ids": ["thfglu_c"]}, "charge": 0, "formula": "C24H27N8O9", "compartment": "c", "id": "thfglu_c"}, {"name": "Thiamin", "notes": {"original_bigg_ids": ["thm_c"]}, "charge": 0, "formula": "C12H17N4OS", "compartment": "c", "id": "thm_c"}, {"name": "Thiamin monophosphate", "notes": {"original_bigg_ids": ["thmmp_c"]}, "charge": 0, "formula": "C12H16N4O4PS", "compartment": "c", "id": "thmmp_c"}, {"name": "L-Threonine", "notes": {"original_bigg_ids": ["thr_DASH_L_c"]}, "charge": 0, "formula": "C4H9NO3", "compartment": "c", "id": "thr__L_c"}, {"name": "L-Threonine", "notes": {"original_bigg_ids": ["thr_DASH_L_m"]}, "charge": 0, "formula": "C4H9NO3", "compartment": "m", "id": "thr__L_m"}, {"name": "L-Threonyl-tRNA(Thr)", "notes": {"original_bigg_ids": ["thrtrna_c"]}, "charge": 0, "formula": "C4H8NO2R", "compartment": "c", "id": "thrtrna_c"}, {"name": "TRNA(Thr)", "notes": {"original_bigg_ids": ["trnathr_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnathr_c"}, {"name": "TRNA(Thr)", "notes": {"original_bigg_ids": ["trnathr_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnathr_m"}, {"name": "L-Threonyl-tRNA(Thr)", "notes": {"original_bigg_ids": ["thrtrna_m"]}, "charge": 0, "formula": "C4H8NO2R", "compartment": "m", "id": "thrtrna_m"}, {"name": "Thymine", "notes": {"original_bigg_ids": ["thym_c"]}, "charge": 0, "formula": "C5H6N2O2", "compartment": "c", "id": "thym_c"}, {"name": "Thiamine diphosphate", "notes": {"original_bigg_ids": ["thmpp_c"]}, "charge": 0, "formula": "C12H16N4O7P2S", "compartment": "c", "id": "thmpp_c"}, {"name": "Thiamin triphosphate C12H16N4O10P3S", "notes": {"original_bigg_ids": ["thmtp_c"]}, "charge": 0, "formula": "C12H16N4O10P3S", "compartment": "c", "id": "thmtp_c"}, {"name": "Reduced thioredoxin", "notes": {"original_bigg_ids": ["trdrd_m"]}, "charge": 0, "formula": "XH2", "compartment": "m", "id": "trdrd_m"}, {"name": "Oxidized thioredoxin", "notes": {"original_bigg_ids": ["trdox_m"]}, "charge": 0, "formula": "X", "compartment": "m", "id": "trdox_m"}, {"name": "Trehalose", "notes": {"original_bigg_ids": ["tre_c"]}, "charge": 0, "formula": "C12H22O11", "compartment": "c", "id": "tre_c"}, {"name": "Alpha,alpha'-Trehalose 6-phosphate", "notes": {"original_bigg_ids": ["tre6p_c"]}, "charge": 0, "formula": "C12H21O14P", "compartment": "c", "id": "tre6p_c"}, {"name": "Trehalose", "notes": {"original_bigg_ids": ["tre_v"]}, "charge": 0, "formula": "C12H22O11", "compartment": "v", "id": "tre_v"}, {"name": "Triglyceride yeast specific C5160H9566O600", "notes": {"original_bigg_ids": ["triglyc_SC_c"]}, "charge": 0, "formula": "C5160H9566O600", "compartment": "c", "id": "triglyc_SC_c"}, {"name": "L-Tryptophan", "notes": {"original_bigg_ids": ["trp_DASH_L_c"]}, "charge": 0, "formula": "C11H12N2O2", "compartment": "c", "id": "trp__L_c"}, {"name": "TRNA(Trp)", "notes": {"original_bigg_ids": ["trnatrp_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnatrp_c"}, {"name": "L-Tryptophanyl-tRNA(Trp)", "notes": {"original_bigg_ids": ["trptrna_c"]}, "charge": 0, "formula": "C11H11N2OR", "compartment": "c", "id": "trptrna_c"}, {"name": "L-Tryptophanyl-tRNA(Trp)", "notes": {"original_bigg_ids": ["trptrna_m"]}, "charge": 0, "formula": "C11H11N2OR", "compartment": "m", "id": "trptrna_m"}, {"name": "L-Tryptophan", "notes": {"original_bigg_ids": ["trp_DASH_L_m"]}, "charge": 0, "formula": "C11H12N2O2", "compartment": "m", "id": "trp__L_m"}, {"name": "TRNA(Trp)", "notes": {"original_bigg_ids": ["trnatrp_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnatrp_m"}, {"name": "L-Tyrosine", "notes": {"original_bigg_ids": ["tyr_DASH_L_c"]}, "charge": 0, "formula": "C9H11NO3", "compartment": "c", "id": "tyr__L_c"}, {"name": "L-Tyrosine", "notes": {"original_bigg_ids": ["tyr_DASH_L_m"]}, "charge": 0, "formula": "C9H11NO3", "compartment": "m", "id": "tyr__L_m"}, {"name": "L-Tyrosine", "notes": {"original_bigg_ids": ["tyr_DASH_L_x"]}, "charge": 0, "formula": "C9H11NO3", "compartment": "x", "id": "tyr__L_x"}, {"name": "L-Tyrosyl-tRNA(Tyr)", "notes": {"original_bigg_ids": ["tyrtrna_c"]}, "charge": 0, "formula": "C9H10NO2R", "compartment": "c", "id": "tyrtrna_c"}, {"name": "TRNA(Tyr)", "notes": {"original_bigg_ids": ["trnatyr_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnatyr_c"}, {"name": "L-Tyrosyl-tRNA(Tyr)", "notes": {"original_bigg_ids": ["tyrtrna_m"]}, "charge": 0, "formula": "C9H10NO2R", "compartment": "m", "id": "tyrtrna_m"}, {"name": "TRNA(Tyr)", "notes": {"original_bigg_ids": ["trnatyr_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnatyr_m"}, {"name": "UMP", "notes": {"original_bigg_ids": ["ump_n"]}, "charge": 0, "formula": "C9H11N2O9P", "compartment": "n", "id": "ump_n"}, {"name": "Dihydrosirohydrochlorin", "notes": {"original_bigg_ids": ["dscl_c"]}, "charge": 0, "formula": "C42H41N4O16", "compartment": "c", "id": "dscl_c"}, {"name": "Uroporphyrinogen III", "notes": {"original_bigg_ids": ["uppg3_c"]}, "charge": 0, "formula": "C40H36N4O16", "compartment": "c", "id": "uppg3_c"}, {"name": "L-Valine", "notes": {"original_bigg_ids": ["val_DASH_L_c"]}, "charge": 0, "formula": "C5H11NO2", "compartment": "c", "id": "val__L_c"}, {"name": "L-Valyl-tRNA(Val)", "notes": {"original_bigg_ids": ["valtrna_c"]}, "charge": 0, "formula": "C5H10NOR", "compartment": "c", "id": "valtrna_c"}, {"name": "TRNA(Val)", "notes": {"original_bigg_ids": ["trnaval_c"]}, "charge": 0, "formula": "R", "compartment": "c", "id": "trnaval_c"}, {"name": "L-Valyl-tRNA(Val)", "notes": {"original_bigg_ids": ["valtrna_m"]}, "charge": 0, "formula": "C5H10NOR", "compartment": "m", "id": "valtrna_m"}, {"name": "TRNA(Val)", "notes": {"original_bigg_ids": ["trnaval_m"]}, "charge": 0, "formula": "R", "compartment": "m", "id": "trnaval_m"}, {"name": "L-Valine", "notes": {"original_bigg_ids": ["val_DASH_L_m"]}, "charge": 0, "formula": "C5H11NO2", "compartment": "m", "id": "val__L_m"}, {"name": "D-Xylulose", "notes": {"original_bigg_ids": ["xylu_DASH_D_c"]}, "charge": 0, "formula": "C5H10O5", "compartment": "c", "id": "xylu__D_c"}, {"name": "Xylitol C5H12O5", "notes": {"original_bigg_ids": ["xylt_c"]}, "charge": 0, "formula": "C5H12O5", "compartment": "c", "id": "xylt_c"}, {"name": "D-Xylose", "notes": {"original_bigg_ids": ["xyl_DASH_D_c"]}, "charge": 0, "formula": "C5H10O5", "compartment": "c", "id": "xyl__D_c"}, {"name": "Pseudouridine 5 phosphate C9H11N2O9P", "notes": {"original_bigg_ids": ["psd5p_c"]}, "charge": 0, "formula": "C9H11N2O9P", "compartment": "c", "id": "psd5p_c"}], "version": 1, "id": "iND750"}